[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"analgesic-consumption\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:analgesic-consumption":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100635048","analgesic-consumption-in-the-early-postoperative-period-a-prospective-observational-pacu-study-100635048",false,"NCT07547618","Analgesic Consumption in the Early Postoperative Period: A Prospective Observational PACU Study","Factors Influencing Analgesic Consumption in the Early Postoperative Period: A Prospective Observational Study in the Post-Anesthesia Care Unit","Inclusion Criteria:\n\n* Adults aged 18 years and older\n* Undergoing elective surgical procedures\n* Admitted to the post-anesthesia care unit (PACU) after surgery\n* Receiving general and\u002For regional anesthesia\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Patients younger than 18 years\n* Emergency surgical procedures\n* Patients transferred directly to the intensive care unit postoperatively\n* PACU stay shorter than 30 minutes\n* Patients unable to communicate or assess pain\n* Incomplete clinical records\n* Refusal to participate in the study","ALL","18 Years",{"count":19,"type":20},254,"ESTIMATED","OBSERVATIONAL","Postoperative pain remains a significant clinical challenge that directly affects patient recovery, functional outcomes, and overall quality of care. Inadequate pain control in the early postoperative period is associated with delayed mobilization, increased risk of complications, prolonged hospital stay, and the development of chronic pain. The post-anesthesia care unit (PACU) represents a critical phase in which pain is actively assessed and managed, and analgesic consumption during this period serves as an objective indicator of analgesic requirements and effectiveness of perioperative pain strategies.\n\nThis prospective observational study aims to identify patient-related, surgical, and anesthesia-related factors influencing analgesic consumption in the early postoperative period among adult patients admitted to the PACU following elective surgery. No additional interventions will be performed, and all perioperative management will follow routine clinical practice. Data will be collected prospectively from clinical records, anesthesia charts, and PACU monitoring forms.\n\nThe primary outcome is total analgesic consumption during the PACU stay. Secondary outcomes include pain intensity assessed using a standardized pain scale at PACU admission and discharge, requirement for rescue analgesia, incidence of postoperative nausea and vomiting, and length of stay in the PACU.\n\nThe findings of this study are expected to contribute to the identification of patients at higher risk for increased analgesic requirements and to support the development of individualized pain management strategies, ultimately improving perioperative care quality and patient outcomes.",[24,25,26],"Postoperative Pain","Analgesic Consumption","Pain Management","RECRUITING","2026-04-26",{"date":30,"type":31},"2026-04-30","ACTUAL",{"date":33,"type":31},"2026-04-05",{"date":35,"type":20},"2026-07-20",{"name":37,"class":38},"Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":16,"minAge":17,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":51,"conditions":52,"keywords":54,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":39},"100628144","postoperative-pain-and-analgesic-use-after-total-knee-arthroplasty-100628144","NCT07457814","Postoperative Pain and Analgesic Use After Total Knee Arthroplasty","Postoperative Pain and Analgesic Consumption in Patients Undergoing Total Knee Arthroplasty Under General Anesthesia With Peripheral Nerve Block Versus Spinal Anesthesia With Peripheral Nerve Block","Inclusion Criteria:\n\n* Age 18-100 years\n* Primary total knee arthroplasty (TKA)\n* ASA physical status I-III\n* Glasgow Coma Scale (GCS) score of 15\n* Ability to understand study procedures and provide informed consent\n* Ability to cooperate during pre-anesthetic evaluation\n* No severe sensory impairment (e.g., blindness, deafness)\n\nExclusion Criteria:\n\n* Revision or reoperation of TKA\n* ASA score IV or higher\n* Refusal to participate or inability to provide informed consent\n* GCS ≤ 14\n* Limited legal capacity\n* Active psychiatric disorder\n* Chronic use of strong opioid analgesics\n* Neurological disease affecting pain perception or cooperation\n* Cognitive impairment or language barrier preventing questionnaire completion\n* Use of anesthesia techniques other than GA + PNB or SA + PNB (e.g., epidural anesthesia, local infiltration without PNB)",true,"100 Years",{"count":50,"type":20},50,"This prospective observational study evaluates postoperative pain intensity and analgesic consumption in patients undergoing total knee arthroplasty (TKA) under different anesthesia techniques. Patients receive either general anesthesia with peripheral nerve block, spinal anesthesia with peripheral nerve block, spinal anesthesia alone, or general anesthesia with an epidural catheter. Pain scores (NRS), analgesic use, adverse effects, patient satisfaction, and the need for therapeutic interventions are assessed during the first 48 hours after surgery. The study aims to identify differences in postoperative pain control and factors associated with hypotension and other complications.",[53,24,25],"Postoperative Pain After Total Knee Arthroplasty",[55,24,56,25,57,58,59,60,26],"Total Knee Arthroplasty","Anesthesia Techniques","Epidural Analgesia","Opioid Use","General Anesthesia","Spinal Anesthesia","NOT_YET_RECRUITING","2026-03-04",{"date":64,"type":31},"2026-03-09",{"date":66,"type":20},"2026-03-01",{"date":68,"type":20},"2027-06-15",{"name":70,"class":38},"Tomas Bata Hospital, Czech Republic"]