[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anesthesia-adverse-effect\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anesthesia-adverse-effect":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,53,80,110],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":32,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100466807","phase-3-propofol-and-etomidate-admixtures-comparisons-trial-peac-trial-100466807",false,"NCT05358535","Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)","PEAC","Inclusion Criteria:\n\n1. Adult patients (age ≥18 years old)\n2. Having endoscopic procedure at CUH with anesthesia\n3. ASA 3 or above\n4. Ejection Fraction test result available\n\nExclusion Criteria:\n\n1. Known allergies or adverse reactions to study drugs or study drug components or preservatives\n2. Patient refusal\n3. Clinician refusal\n4. Documented cognitive impairments precluding subject ability to consent for themselves unless a surrogate documented legally acceptable decision maker consents for patient participation\n5. Prisoner or incarcerated or patients held by law enforcement officials in custody\n6. Pregnancy or patient refusal for pregnancy testing or screening (standard UTSW policy and protocol requires pregnancy testing for appropriate patients prior to anesthesia)","ALL","18 Years",{"count":19,"type":20},200,"ESTIMATED","INTERVENTIONAL",[23],"PHASE3","The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%\u002F75% (P2E7), and one using an admixture of propofol and etomidate at a ratio by volume of 75%\u002F25% (P7E2), for anesthesia during endoscopic procedures at the Clements University Hospital (CUH) endoscopy lab (Endo).",[26,27,28,29,30,31],"Anesthesia","Propofol Adverse Reaction","Etomidate Adverse Reaction","Anesthesia Complication","Anesthesia; Adverse Effect","Anesthesia; Reaction",[33,34,35,36,37,38,39],"anesthesia","anesthesiology","adverse drug reaction","drug side effect","sedation","cardiopulmonary","hemodynamics","RECRUITING","2026-01-16",{"date":43,"type":44},"2026-01-20","ACTUAL",{"date":46,"type":44},"2022-09-19",{"date":48,"type":20},"2027-03",{"name":50,"class":51},"University of Texas Southwestern Medical Center","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":16,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":21,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":52},"100541061","language-during-inhalational-induction-100541061","NCT06324955","Language During Inhalational Induction","A Prospective Randomized Study Comparing Positive Language vs Common Language During Inhalational Induction","Inclusion Criteria:\n\n* ASA 1 and 2 (Healthy Patients)\n* Non-emergent cases\n* 5-10 year olds\n* Patients receiving inhalational induction\n\nExclusion Criteria:\n\n* Non-English speaking\n* History of prior inhalational inductions\n* Hearing difficulty\n* Behavioral difficulty (Autism, Oppositional Defiant Disorder)\n* Patients receiving premedication other than midazolam","5 Years","10 Years",{"count":63,"type":20},128,[65],"NA","The aim of this study is to compare the impact of common (standard of care) language vs positive language used by clinicians during inhalational induction of anesthesia on anxiety and negative behaviors in children. This is a prospective randomized parallel group trial. Patients will be randomized 1:1 to the common\u002Fstandard language group or the positive language group.",[68,30],"Emergence Delirium",[70],"Anesthesia induction","2026-01-08",{"date":73,"type":44},"2026-01-09",{"date":75,"type":44},"2024-04-08",{"date":77,"type":20},"2027-04",{"name":79,"class":51},"Boston Children's Hospital",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":16,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":4,"studyType":21,"phases":90,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":52},"100560396","apnoeic-oxygenation-during-pediatric-tracheal-intubation-100560396","NCT06576596","Apnoeic Oxygenation During Pediatric Tracheal Intubation","Apnoeic Oxygenation During Pediatric Tracheal Intubation: a Study Protocol for a Single-center, Cluster Randomized Clinical Trial (ApOx-Pedi-Trial)","Inclusion Criteria:\n\n* children 0-6 years\n* ASA status I-III\n* Elective surgery\u002Fintervention under general anaesthesia\n\nExclusion Criteria:\n\n* refusal to participate in the study by the patients or their legal guardians\n* ASA classification IV = patients with life-threatening disease\n* Existing oxygen therapy prior to surgery\n* Surgery\u002Fintervention in the ENT area with contraindication for oxygen goggles\n* Injuries\u002Ftrauma in the ENT and mouth\u002Fnose area\n* Anatomical anomalies\u002Fmalformations in the ENT and mouth\u002Fnose area\n* Chronical hypoxemia (e.g. patients with cyanotic heart diseases)\n* language barrier (parent\u002Fguardian)\n* emergency interventions\n* refusal by the attending physician\n* lack of presence of the pediatric anesthesiology consultant\n* Situational inability to perform apnoeic oxygenation or inability to obtain baseline NIRS values at room air within 60 seconds from the first attempt due to agitation of the patient","0 Years","6 Years",{"count":19,"type":20},[65],"The goal of this randomized, controlled, single-blinded clinical trial is to evaluate the effectiveness of apnoeic Oxygenation in pediatric anesthesia. The main question it aims to answer are:\n\nprimary outcome measure: The primary outcome will be the lowest SpO₂ value recorded during the apnoeic period.\n\nsecondary outcome measure:\n\n* Differences in intubation first-pass-success (key secondary objective)\n* Temporal differences to achieve successful intubation\n* Differences in time to oxygen desaturation\n* Differences in heart rate and mean arterial blood pressure decrease\n* Differences in the incidence of anesthesia-related adverse events\n\nThe study participants are randomized two age dependents groups. Either in the control group without the use of apnoeic oxygenation or in the intervention group with the use of apnoeic oxygenation.\n\nThe study population will be divided into two independent cohorts, each consisting of 100 patients. The first cohort, designated as \"infants\" will include all patients aged up to 24 months, while the second cohort, termed \"children\" will comprise patients aged older than 24 months and up to six years.\n\nWithin each cohort, patients will be randomized into an intervention group and a control group, with 50 patients assigned to each. This randomization will ensure that, for both the Infant and Children Groups, half of the participants (n=50) will receive the intervention, while the other half (n=50) will serve as controls.\n\nStatistical analysis of primary and secondary endpoints will be conducted independently for each cohort. This stratified approach will allow for targeted evaluation of age-specific effects of the intervention, as well as comparison between intervention and control outcomes within each age-defined cohort.",[26,93,30],"Airway Complication of Anesthesia",[95,96,97,98,99,100],"Airway Management","Pediatric Anesthesia","Apnoeic Oxygenation","Apneic Oxygenation","Oxygen","Tracheal Intubation","2025-02-26",{"date":103,"type":44},"2025-03-03",{"date":105,"type":44},"2024-09-09",{"date":107,"type":20},"2025-08-31",{"name":109,"class":51},"University Hospital Heidelberg",{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":118,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":119,"targetDuration":121,"studyType":122,"phases":4,"briefSummary":123,"conditions":124,"keywords":4,"overallStatus":128,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":52},"100506068","registry-of-anesthesia-and-perioperative-medicine-100506068","NCT05869578","Registry of Anesthesia and Perioperative Medicine","Registry of Patients Subjected to the Perioperative Care of the Anesthesia Service of Clinica Alemana of Santiago Chile","RAMP","Inclusion Criteria:\n\n* All individuals\n* Individuals agreeing to participate in the study by signing a consent\n\nExclusion Criteria:\n\n* The subjects who had insufficient data in their files",true,{"count":120,"type":20},10000,"1 Year","OBSERVATIONAL","To assess mortality and morbidity associated to anesthesia interventions",[125,126,127,30,29,31],"Perioperative Complication","Perioperative\u002FPostoperative Complications","Anesthesia Morbidity","NOT_YET_RECRUITING","2023-05-19",{"date":131,"type":44},"2023-05-22",{"date":133,"type":20},"2023-06-01",{"date":135,"type":20},"2045-01-01",{"name":137,"class":51},"Clinica Alemana de Santiago"]