[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anesthesia-and-analgesia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anesthesia-and-analgesia":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,56,86],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":55},"100611379","peng-block--lia-for-endoprosthesis-surgery-100611379",false,"NCT07239817","PENG Block + LIA For Endoprosthesis Surgery","PENG 360°: PENG Block + LIA Nella Endoprotesi di Anca.","PENG 360°","Inclusion Criteria:\n\n* Provision of signed and dated informed consent form.\n* Scheduled for hip endoprosthesis surgery for femoral fracture with an anterior approach.\n* Age 18 years or older.\n* Willing and able to comply with the study protocol.\n\nExclusion Criteria:\n\n* Failure to provide informed consent.\n* Age less than 18 years.\n* Known allergy to local anesthetics or other medications used in the protocol.\n* Presence of infection at the planned injection site.\n* Pre-existing hip prosthesis or prior major surgery on the same hip (e.g., revision surgery).\n* ASA physical status class \\> IV.\n* Administration of intraoperative opiates or conversion to general anesthesia.","ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to learn if a new local anesthesia technique can control pain as well as the standard spinal anesthesia for adults having hip endoprosthesis surgery. The main questions it aims to answer are:\n\n* Is the new local anesthesia technique as effective as standard spinal anesthesia in managing pain during the first two days after surgery?\n* Does the new technique allow participants to move their leg sooner after the operation?\n\nResearchers will compare the new local anesthesia technique (numbing medicine injected directly around the hip joint) to standard spinal anesthesia (a numbing injection in the back) to see if the new technique works just as well for pain control while possibly causing fewer side effects like nausea.\n\nParticipants who join this study will be randomly placed into one of two groups.\n\nOne group will receive the standard spinal anesthesia before their surgery.\n\nThe other group will receive the new local anesthesia technique before their surgery.\n\nAfter the operation, researchers will track the amount of extra pain medicine each participant uses and will check their ability to move their hip, knee, and foot.",[27,28,29,30,31,32],"Hip Fractures","Arthroplasty, Replacement, Hip","Pain, Postoperative","Anesthesia and Analgesia","Nerve Block","Local Anesthesia Infiltration",[34,35,36,37,38,39,40,41,42],"Pericapsular Nerve Group Block","PENG block","Local Infiltration Analgesia","Spinal Anesthesia","Hip Arthroplasty","Postoperative Pain","Femoral Fractures","Ultrasound Guidance","Early Mobilization","RECRUITING","2026-06-10",{"date":46,"type":47},"2026-06-12","ACTUAL",{"date":49,"type":47},"2025-12-09",{"date":51,"type":21},"2026-12-30",{"name":53,"class":54},"ASST Gaetano Pini-CTO","OTHER",1,{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":64,"enrollmentInfo":65,"targetDuration":4,"studyType":22,"phases":67,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":55},"100577071","comparison-of-the-efficacy-of-celiac-plexus-blockade-esp-and-lidocaine-infusion-under-ofa-100577071","NCT06793527","Comparison of the Efficacy of Celiac Plexus Blockade, ESP and Lidocaine Infusion Under OFA","Comparison of the Efficacy of Celiac Plexus Blockade, Erector Spinae Compartment Blockade (ESP), and Intravenous Lidocaine Infusion Under Opioid-free Anesthesia in Patients Undergoing Bariatric Surgery","LECO","Inclusion Criteria:\n\n* Patients over 18 years who underwent laparoscopic bariatric surgery\n* Must be able to sign agreement for study\n\nExclusion Criteria:\n\n* Patients with a history of allergic reactions to drugs\n* Patients with a history of drug addiction\n* Patients with chronic pain who require analgesics\n* History of hospitalization for psychiatric disorders\n* Preoperative pulse oximetry (SpO2) \\\u003C 95 %\n* bradycardia (HR\\\u003C50bpm)\n* hypotension\n* atrioventricular block\n* intraventricular or sinus block\n* Blood clotting disorders\n* Pregnant\u002Flactating women\n* Cognitive impairment\n* Unable to read consent","75 Years",{"count":66,"type":21},300,[24],"Modern anesthesiology, in search of alternatives to opioid-based pain management, is turning to low-opioid and non-opioid protocols. Replacing opioids with non-opioid analgesics, co-analgesics, and regional and local anesthesia techniques allows avoiding the adverse effects of opioids while maintaining satisfactory analgesia. This is of particular importance in bariatric surgery, where reducing the incidence of respiratory depression, sedation, opioid hyperalgesia, and postoperative nausea and vomiting is a priority. Standard non-opioid anesthesia (OFA) includes ketamine, lidocaine, and dexmedetomidine infusions, while regional techniques additionally reduce the need for analgesics. Despite the widespread use of these methods, there is no clear data on the superiority of any of them in bariatric procedures.",[70,30],"Regional Anaesthesia",[72,73,74,75,76],"ESP","celiac plexus block","OFA","erector spinal plane block","opioid free anesthesia","2025-04-02",{"date":79,"type":47},"2025-04-04",{"date":81,"type":47},"2025-02-06",{"date":83,"type":21},"2026-12-31",{"name":85,"class":54},"Jagiellonian University",{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":4,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":17,"minAge":93,"maxAge":94,"enrollmentInfo":95,"targetDuration":4,"studyType":97,"phases":4,"briefSummary":98,"conditions":99,"keywords":4,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":55},"100388345","diaphragmatic-breathing-exercises-in-total-knee-arthroplasty-patients-100388345","NCT04336579","Diaphragmatic Breathing Exercises in Total Knee Arthroplasty Patients","Diaphragmatic Breathing Exercises As An Analgesia Adjunct in Total Knee Arthroplasty Patients in the Perioperative Period","Inclusion Criteria:\n\n* Patients (participants) undergoing total knee arthroplasty with a continuous peripheral nerve block catheter\n\nExclusion Criteria:\n\n* Inability to perform or learn diaphragmatic breathing exercises or do not wish to participate in diaphragmatic breathing or study protocol\n* Pregnant patients\n* Patients without continuous peripheral nerve block catheter","50 Years","90 Years",{"count":96,"type":21},50,"OBSERVATIONAL","Rationale: While total knee replacements (TKA) are one of the most commonly performed surgical procedures in the United States, this procedure can also be very painful. Postoperative mobilization and rehabilitation is vital to a patient's recovery, but inadequate pain control can impede patients' progress. Diaphragmatic breathing is an additional non-pharmacological and non-invasive tool with no adverse effects that could aid in recovery. This will serve as a pilot study for a possible larger controlled trials.",[30],"2024-08-25",{"date":102,"type":47},"2024-08-27",{"date":104,"type":47},"2024-06-10",{"date":106,"type":21},"2024-10-01",{"name":108,"class":54},"University of Southern California"]