[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anesthesia-awareness\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anesthesia-awareness":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,41,71,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100635959","fear-and-anxiety-in-anesthesia-nave-patients-pre-operatively-vs-post-operatively-100635959",false,"NCT07559461","Fear and Anxiety in Anesthesia-Naïve Patients Pre-operatively vs Post-operatively","Fear and Anesthesia: How Anxiety and Fear in Anesthesia-Naïve Patients Changes From Preop to Postop","Inclusion Criteria:\n\n* 18 years old or over\n* Patients scheduled to undergo surgeries such as but not limited to:\n\ncholecystectomies, appendectomies, hernia repairs, breast surgeries, plastic surgeries, thyroidectomy, parathyroidectomy, tonsillectomy, adenoidectomy, lithotripsy, stent placement, kidney stone surgeries, cystoscopies, bladder tumors, ovarian cystectomies, hysterectomies, tubal ligation, hysteroscopy, Intrauterine Device (IUD) insertion, knee replacement, hip replacement, fracture pinning, sports injury surgery such as knee and shoulder scopes. OR patients undergoing procedures such as but not limited to: colonoscopies and endoscopies\n\n* Patient undergoing anesthesia for the first time\n* Patients who are not pregnant by self report\n\nExclusion Criteria:\n\n* Patients under 18\n* Patients who are pregnant\n* Patients undergoing high-risk surgeries\n* Patients undergoing cancer-related procedures\n* Non-English speaking patients\n* Patients that experience mental status change postoperatively as determined by the medical teams caring for the patient\n* Patients with an existing anxiety disorder, or psychiatric diagnoses\n* Patients on benzodiazepines, antidepressants, chronic opioids","ALL","18 Years",{"count":19,"type":20},40,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to understand how fear and anxiety felt by anesthesia-naive patients compares before versus after their scheduled surgery. Patients who are scheduled to undergo a low-risk surgery\u002Fprocedure and have never had anesthesia before will be asked to:\n\n1. Fill out a survey before their surgery in the perioperative setting\n2. Answer follow-up questions over the phone a few days after their surgery.",[24,25],"Anxiety","Anesthesia Awareness",[27,24],"Anesthesia-naïve","RECRUITING","2026-04-29",{"date":31,"type":32},"2026-05-05","ACTUAL",{"date":34,"type":32},"2026-02-12",{"date":36,"type":20},"2027-02",{"name":38,"class":39},"Stony Brook University","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":49,"targetDuration":51,"studyType":21,"phases":4,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":40},"100634172","deep-learning-framework-for-continuous-depth-of-anesthesia-forecasting-100634172","NCT07536230","Deep Learning Framework for Continuous Depth of Anesthesia Forecasting","Validation of a Deep Learning Framework for Continuous Forecasting of Pharmacodynamic Responses and Physiological Trajectories During General Anesthesia","Inclusion Criteria:\n\n* Patients scheduled for elective surgery requiring general anesthesia.\n* Procedures requiring continuous depth of anesthesia monitoring (BIS).\n\nExclusion Criteria:\n\n\\- Procedures where the primary anesthetic plan does not involve continuous electronic data capture.",true,{"count":50,"type":20},115,"1 Day","The integration of Artificial Intelligence (AI) in anesthesiology offers the potential to shift patient monitoring from reactive to predictive. Deep learning architectures, specifically Long Short-Term Memory (LSTM) networks, excel at processing complex, time-series data to forecast future clinical states.\n\nWhile standard PK\u002FPD models (such as the state of the art Eleveld model for Propofol and Remifentanil) estimate target-site drug concentrations (Ce), they do not account for real-time, patient-specific dynamic responses. This study aims to deploy an AI framework designed to predict future physiological states.",[54,55,56,57,58,59,25,60],"BIS","BIS-EEG","Artifical Intelligence","Intraoperative","Machine Learning","Anesthesia","Predictive Model","NOT_YET_RECRUITING","2026-04-10",{"date":64,"type":32},"2026-04-17",{"date":66,"type":20},"2026-06-01",{"date":68,"type":20},"2026-09-01",{"name":70,"class":39},"Universitair Ziekenhuis Brussel",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":100},"100515434","trajectories-of-recovery-after-intravenous-propofol-versus-inhaled-volatile-anesthesia-trial-100515434","NCT05991453","Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial","THRIVE","Inclusion Criteria\n\nEach patient must meet all of the following criteria:\n\n1. Aged 18 years or older\n2. Undergoing elective non-cardiac surgery expected to last ≥ 60 min requiring general anesthesia with a tracheal tube or laryngeal mask airway (or similar supra-glottic device)\n\nExclusion Criteria\n\nPatients will not be enrolled if any of the following criteria are met:\n\n1. Inability to provide informed consent in English (at all study sites) or Spanish (at sites where Spanish consent is provided as an option)\n2. Pregnancy (based on patient report or positive test on the day of surgery)\n3. Surgical procedure requiring general, regional, neuraxial anesthesia administered by an anesthesia clinician (anesthesiologist, CRNA, anesthesiology assistant) occurring within 30 days prior to or planned to occur within 30 days after surgery date\n4. Contraindication to propofol TIVA or INVA (for example, documented allergy to propofol, history of severe postoperative nausea or vomiting, concern for or history of malignant hyperthermia) based on self-report\n5. Surgical procedures requiring a specific general anesthesia technique (for example, TIVA required for neuromonitoring).\n6. Locally approved, written protocol mandating a particular anesthetic technique\n7. History of possible or definite intraoperative awareness during general anesthesia based on patient self-report\n8. Planned postoperative intubation\n9. Current incarceration",{"count":79,"type":20},13000,"INTERVENTIONAL",[82],"NA","The investigators will conduct a 13,000-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries",[85,86,25,59,87,88,89,90],"Surgery-Complications","Anesthesia Complication","Surgery","Quality of Life","Pain, Postoperative","Anesthesia Morbidity","2025-07-30",{"date":93,"type":32},"2025-08-05",{"date":95,"type":32},"2023-09-13",{"date":97,"type":20},"2028-07-31",{"name":99,"class":39},"Washington University School of Medicine",20,{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":80,"phases":110,"briefSummary":111,"conditions":112,"keywords":113,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":40},"100322308","manual-versus-targer-controll-infusion-in-reduction-of-awareness-and-dreaming-100322308","NCT03476213","Manual Versus Targer-controll Infusion in Reduction of Awareness and Dreaming","Reduction of Awareness and Dreaming During Neurosurgical Procedures Using Target- Controlled Infusion, Comparison With Manual Total Intravenous Anesthesia TIVA.","Inclusion Criteria:\n\n* Glasgow Coma scale 15\n* ASA Physical Status Classification System I - III\n* planed surgery for brain tumor to 5 hours\n* postoperative awakening\n\nExclusion Criteria:\n\n* NYHA III, IV\n* abuse of stimulating drugs, grass, alcohol dependence\n* BMI over 40 in females and over 35 in men\n* propofol alergie\n* awake operations\n* postoperative arteficial ventilation",{"count":109,"type":20},80,[82],"This study compares manual total intravenous anesthesia (TIVA) and target-controll infusion (TCI) in reduction of awareness and dreaming, and the haemodynamical stability during operation. Half of patients will be anesthetized using manual TIVA and other half using TCI.",[25],[25,114,115,116],"Dreaming in anesthesia","Total intravenous anesthesia","Target-controll infusion","2024-05-09",{"date":119,"type":32},"2024-05-10",{"date":121,"type":32},"2018-03-16",{"date":123,"type":20},"2027-06-30",{"name":125,"class":39},"University Hospital Hradec Kralove"]