[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anesthesia-complication\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anesthesia-complication":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,43,72,107,135,167,196,220,246],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100636275","determinants-of-technical-success-and-safety-in-therapeutic-ercp-for-obstructive-jaundice-100636275",false,"NCT07563569","Determinants of Technical Success and Safety in Therapeutic ERCP for Obstructive Jaundice","Determinants of Technical Success and Safety in Therapeutic ERCP for Obstructive Jaundice: A Prospective Comparative Study.","ERCP","Inclusion Criteria:\n\n* Adult patients above 18 years old.\n* Patient with obstructive jaundice as an indication for therapeutic ERCP.\n* Provided written informed consent.\n\nExclusion Criteria:\n\n* Patients below 18 years old.\n* Indications for ERCP other than obstructive jaundice.\n* with coagulopathy not corrected prior to procedure.\n* severe active cardiopulmonary comorbidities.\n* Previous altered upper GIT anatomy (e.g gastric by-pass).\n* Pregnancy","ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","compare the impact of type of anesthesia on ERCP including technical success, rate of complications, peri procedural safety, patient and endoscopist satisfaction in adult patients with obstructive jaundice",[27,15,28,29],"Obstructive Jaundice","Anesthesia Complication","Anesthesia Effectiveness",[15],"NOT_YET_RECRUITING","2026-04-25",{"date":34,"type":35},"2026-05-04","ACTUAL",{"date":37,"type":21},"2026-05-20",{"date":39,"type":21},"2027-05-20",{"name":41,"class":42},"Sohag University","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":18,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":56,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":71},"100585737","complications-related-to-the-anaesthesia-during-airway-endoscopy-in-children-with-tracheostomy-100585737","NCT06906263","Complications Related to the Anaesthesia During Airway Endoscopy in Children With Tracheostomy.","All patients:\n\nunder the age of 18 years with tracheostomy undergoing surveillance airway endoscopy approved for anesthesia\n\nwill be included within the time frame of the study (3 years). Patients may be included multiple times during the study period.\n\nExclusion Criteria:\n\nPatients will be excluded from the study if the airway endoscopy is a non-elective emergency procedure.\n\nPatients undergoing concurrent major surgery during the same session will be included in the study but excluded from analysis of postoperative symptoms (secondary outcome measure). This is because postoperative well-being cannot be reliably attributed to the airway endoscopy alone when major surgery is performed simultaneously.\n\nThe same patient may be eligible for inclusion at multiple time points during the inclusion period if subject to subsequent airway endoscopies that meet the inclusion criteria.",{"count":50,"type":21},80,"OBSERVATIONAL","The goal of this observational study is to investigate the incidence of severe anaesthesiologic complications during anaesthesia in children with tracheostomy undergoing surveillance airway endoscopy. The main question it aims to answer is how common severe anaesteshiologic complications are in these patients and investigate if there is an association between severe anaesthesiologic complications and patient related factors.\n\nPrimary outcome: The incidence of severe anaesthesiologic complications in children with tracheostomy undergoing surveillance airway endoscopy.\n\nSecondary outcome: The association between severe anaesthesiologic complications and patient related factors: age at tracheostomy, age at surveillance endoscopy, ventilator dependence, current and previously diagnosed tracheostomy related airway complications.\n\nAll children under 18 yrs. of age with a tracheostomy accepted for general anaesthesia undergoing surveillance airway endoscopy at the Long term Intensive Care unit at Karolinska University Hospital Stockholm Sweden will be eligable for inclusion. The anaesthesia will be conducted according to current practise and complications will recorded by the anaesthesiologist in charge. Participants may only be included several times during the study period.",[28,54,55],"Tracheostomy Complications","Children Receiving General Anesthesia",[57,58,59,60],"Tracheostomy","Pediatric","Anesthesia complication","general anesthesia","RECRUITING","2026-03-17",{"date":64,"type":35},"2026-03-20",{"date":66,"type":35},"2025-03-31",{"date":68,"type":21},"2028-03-31",{"name":70,"class":42},"Karolinska Institutet",1,{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":22,"phases":81,"briefSummary":83,"conditions":84,"keywords":90,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":71},"100466807","phase-3-propofol-and-etomidate-admixtures-comparisons-trial-peac-trial-100466807","NCT05358535","Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)","PEAC","Inclusion Criteria:\n\n1. Adult patients (age ≥18 years old)\n2. Having endoscopic procedure at CUH with anesthesia\n3. ASA 3 or above\n4. Ejection Fraction test result available\n\nExclusion Criteria:\n\n1. Known allergies or adverse reactions to study drugs or study drug components or preservatives\n2. Patient refusal\n3. Clinician refusal\n4. Documented cognitive impairments precluding subject ability to consent for themselves unless a surrogate documented legally acceptable decision maker consents for patient participation\n5. Prisoner or incarcerated or patients held by law enforcement officials in custody\n6. Pregnancy or patient refusal for pregnancy testing or screening (standard UTSW policy and protocol requires pregnancy testing for appropriate patients prior to anesthesia)",{"count":80,"type":21},200,[82],"PHASE3","The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%\u002F75% (P2E7), and one using an admixture of propofol and etomidate at a ratio by volume of 75%\u002F25% (P7E2), for anesthesia during endoscopic procedures at the Clements University Hospital (CUH) endoscopy lab (Endo).",[85,86,87,28,88,89],"Anesthesia","Propofol Adverse Reaction","Etomidate Adverse Reaction","Anesthesia; Adverse Effect","Anesthesia; Reaction",[91,92,93,94,95,96,97],"anesthesia","anesthesiology","adverse drug reaction","drug side effect","sedation","cardiopulmonary","hemodynamics","2026-01-16",{"date":100,"type":35},"2026-01-20",{"date":102,"type":35},"2022-09-19",{"date":104,"type":21},"2027-03",{"name":106,"class":42},"University of Texas Southwestern Medical Center",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":111,"acronym":112,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":114,"targetDuration":4,"studyType":22,"phases":116,"briefSummary":117,"conditions":118,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":134},"100515434","trajectories-of-recovery-after-intravenous-propofol-versus-inhaled-volatile-anesthesia-trial-100515434","NCT05991453","Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial","THRIVE","Inclusion Criteria\n\nEach patient must meet all of the following criteria:\n\n1. Aged 18 years or older\n2. Undergoing elective non-cardiac surgery expected to last ≥ 60 min requiring general anesthesia with a tracheal tube or laryngeal mask airway (or similar supra-glottic device)\n\nExclusion Criteria\n\nPatients will not be enrolled if any of the following criteria are met:\n\n1. Inability to provide informed consent in English (at all study sites) or Spanish (at sites where Spanish consent is provided as an option)\n2. Pregnancy (based on patient report or positive test on the day of surgery)\n3. Surgical procedure requiring general, regional, neuraxial anesthesia administered by an anesthesia clinician (anesthesiologist, CRNA, anesthesiology assistant) occurring within 30 days prior to or planned to occur within 30 days after surgery date\n4. Contraindication to propofol TIVA or INVA (for example, documented allergy to propofol, history of severe postoperative nausea or vomiting, concern for or history of malignant hyperthermia) based on self-report\n5. Surgical procedures requiring a specific general anesthesia technique (for example, TIVA required for neuromonitoring).\n6. Locally approved, written protocol mandating a particular anesthetic technique\n7. History of possible or definite intraoperative awareness during general anesthesia based on patient self-report\n8. Planned postoperative intubation\n9. Current incarceration",{"count":115,"type":21},13000,[24],"The investigators will conduct a 13,000-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries",[119,28,120,85,121,122,123,124],"Surgery-Complications","Anesthesia Awareness","Surgery","Quality of Life","Pain, Postoperative","Anesthesia Morbidity","2025-07-30",{"date":127,"type":35},"2025-08-05",{"date":129,"type":35},"2023-09-13",{"date":131,"type":21},"2028-07-31",{"name":133,"class":42},"Washington University School of Medicine",20,{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":141,"eligibilityCriteria":142,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":143,"targetDuration":145,"studyType":51,"phases":4,"briefSummary":146,"conditions":147,"keywords":152,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":166},"100387938","perioperative-management-evaluation-in-patients-with-cied-100387938","NCT04331249","Perioperative Management Evaluation in Patients With CIED","Perioperative Management Evaluation in Patients With Implanted Cardiac Electronic Devices","EVINCE","Inclusion Criteria:\n\n* implanted CIED (e.g. pacemaker, ICD, CRT),\n* performed (non-CIED related) surgical or catheter-based procedure,\n* data from peri-procedural CIED interrogation available\n* age \\>18 years\n\nExclusion Criteria:\n\n* no implanted CIED,\n* no data from any peri-interventional CIED interrogation available",{"count":144,"type":21},500,"1 Month","Background: Recommendations for peri-operative management in patients with implanted cardiac electronic devices (CIED) are often based on older data from case reports and small collectives.\n\nObjective: To evaluate the peri-operative management and outcome of patients with implanted CIED undergoing non-CIED related surgery or catheter-interventional procedures in clinical routine.\n\nStudy design: bi-center, non-randomized, observational registry, retrospective data-collection, on-going prospective patient enrollment, descriptive statistics\n\nPrimary endpoint: number and type of peri-operative adverse device related events (ADE) Secondary endpoints: pre-interventional data (patient characteristics, data from CIED interrogation); peri-interventional data (type of surgery\u002Fintervention, anesthesiology techniques, any AE), postinterventional data (data from post-interventional CIED interrogation, need for reprogramming \u002F device revision).\n\nInclusion criteria: implanted CIED, non-CIED related surgical or catheter-based intervention, peri-procedural CIED interrogation, age \\>18 years Exclusion criteria: no implanted CIED, no data from any peri-procedural CIED interrogation available\n\nPatient enrollment: retrospectively beginning from 2008, further on-going prospective inclusion Sample size: For the observational study, there is no pre-specified sample size. Data from more than 500 patients undergoing \\> 700 interventions are expected.",[148,149,150,28,151],"Cardiac Pacemaker Malfunction","ICD Malfunction","Cardiac Pacemaker Electrical Interference","Surgery--Complications",[153,154,155,156],"pacemaker","implanted cardioverter defibrillator","cardiac resynchronisation therapy","management, peri-operative","2024-10-11",{"date":159,"type":35},"2024-10-15",{"date":161,"type":35},"2018-11-27",{"date":163,"type":21},"2030-12-31",{"name":165,"class":42},"Klinikum-Fuerth",2,{"id":168,"slug":169,"hasResults":11,"nctId":170,"briefTitle":171,"officialTitle":172,"acronym":173,"eligibilityCriteria":174,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":175,"enrollmentInfo":176,"targetDuration":4,"studyType":22,"phases":178,"briefSummary":179,"conditions":180,"keywords":183,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":188,"lastUpdatePostDateStruct":189,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":71},"100565250","preoperative-blood-volume-optimization-using-transthoracic-echocardiography-100565250","NCT06639737","Preoperative Blood Volume Optimization Using Transthoracic Echocardiography","Effect of Preoperative Stroke Volume Optimization Using Transthoracic Echocardiography on Arterial Hypotension Following Induction of Intravenous Anesthesia. A Prospective, Double Blinded Randomized Study.","EchOptimal","Inclusion Criteria:\n\n* Patient aged 18 years or older,\n* Affiliated with social security,\n* Informed about the study and having signed the informed consent form,\n* Requires surgical intervention under general anesthesia,\n* Intermediate or high risk of cardiovascular events within 30 days,\n* ASA phyiscal status Classification 3 or 4\n\nExclusion Criteria:\n\n\\- Pregnant or breastfeeding women,\n\n* Patients under guardianship, curatorship, judicial protection, or legal protection,\n* Minors,\n* Patients with contraindications to intravenous induction with Propofol and Remifentanil,\n* Patients not fasting at the time of surgery,\n* Patients with an immediate life-threatening emergency or requiring surgery without delay to ensure survival,\n* Patients with contraindications for placing an arterial pressure catheter in the radial artery: bilateral negative Allen's test indicating absence of ulnar collateral circulation, Raynaud's syndrome, Buerger's disease, severe dyslipidemias,\n* Patients with characteristics making the measurement of ITVSAo uninterpretable: atrial fibrillation, non-sinus electrocardiogram, severe valvulopathy, documented right or left heart failure,\n* Patients under general anesthesia before arrival in the operating room,\n* Patients receiving aminergic support before anesthetic induction,\n* Patients requiring rapid sequence induction,\n* Patients treated with ACE inhibitors\u002FARBs who have not discontinued the treatment on the day of the procedure","99 Years",{"count":177,"type":21},220,[24],"Immediately following the induction of general anesthesia, arterial hypotension may occur with an incidence of about 40% in patients classified as ASA 3 or 4. Perioperative arterial hypotension is associated with increased perioperative morbidity and mortality. The increased mortality associated with perioperative arterial hypotension has been reported up to 30 and 90 days after surgery. This association appears to be both dose-dependent and time-dependent (severity and duration of arterial hypotension).\n\nEchOptimal study aims to determine whether non invasive preoperative stroke volume optimization using transthoracic echocardiography (TTE) can reduce the incidence and severity arterial hypotension following induction of general anesthesia.\n\nThis is prospective, randomized, controlled, double blinded study approved by ethics comittee.\n\nThe primary objective of this study is to compare the incidence of arterial hypotension (mean arterial pressure \\\u003C 65 mmHg) within the first 15 minutes following the induction of general anesthesia, between 2 groups :\n\n* standard current care (stroke volume optimized after induction of general anesthesia using oesophageal doppler) and\n* preopertaive stroke volume optimization using transthoracic echocardiography measument of subaortic velocity time integral.",[85,28,181,182],"Anesthesia Induction","Arterial Hypotension",[184,185,60,186,187],"preoperative stroke volume optimization echocardiography","arterial hypotension","transoesophageal doppler","sub aortic velocity time integral","2024-10-10",{"date":159,"type":35},{"date":191,"type":35},"2024-10-04",{"date":193,"type":21},"2027-12-30",{"name":195,"class":42},"University Hospital, Caen",{"id":197,"slug":198,"hasResults":11,"nctId":199,"briefTitle":200,"officialTitle":201,"acronym":4,"eligibilityCriteria":202,"healthyVolunteers":11,"sex":17,"minAge":203,"maxAge":204,"enrollmentInfo":205,"targetDuration":4,"studyType":22,"phases":207,"briefSummary":208,"conditions":209,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":211,"lastUpdatePostDateStruct":212,"startDateStruct":214,"completionDateStruct":216,"leadSponsor":218,"locationsCount":71},"100534937","pcv-vg-in-pediatric-laparoscopic-surgery-100534937","NCT06245317","PCV-VG in Pediatric Laparoscopic Surgery","Effects of Pressure Controlled-volume Guarantee Ventilation on Respiratory Mechanics in Pediatric Laparoscopic Surgery","Inclusion Criteria:\n\n* ASA physical status I-II.\n* Both sexes.\n* Age: 1-8 years old.\n* Scheduled for elective abdominal or urologic laparoscopic surgery.\n* BMI between the 5th and 95th percentiles.\n\nExclusion Criteria:\n\n* ASA physical status more than II.\n* Pre-existing lung disease.\n* Pre-operative chest infection.\n* Any thoracic deformities.\n* Unsatisfactory pre-operative arterial oxygen saturation or haemoglobin level.\n* Patients with cardiac, hepatic, or renal diseases.\n* BMI above and below the 95th and 5th percentile respectively.","1 Year","8 Years",{"count":206,"type":21},75,[24],"This Study will aim to compare the effects of Pressure Controlled Ventilation - Volume Guarantee (PCV-VG) mode with volume control ventilation (VCV) and pressure control ventilation (PCV) modes on respiratory mechanics (including the dynamic compliance, PIP, mean airway pressure, driving pressure..etc) and oxygenation in pediatric laparoscopic surgery.",[28,210],"Mechanical Ventilation Complication","2024-07-29",{"date":213,"type":35},"2024-07-30",{"date":215,"type":35},"2024-02-01",{"date":217,"type":21},"2025-01",{"name":219,"class":42},"Assiut University",{"id":221,"slug":222,"hasResults":11,"nctId":223,"briefTitle":224,"officialTitle":225,"acronym":226,"eligibilityCriteria":227,"healthyVolunteers":228,"sex":17,"minAge":229,"maxAge":230,"enrollmentInfo":231,"targetDuration":4,"studyType":22,"phases":233,"briefSummary":234,"conditions":235,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":240,"completionDateStruct":242,"leadSponsor":244,"locationsCount":4},"100552446","this-study-assess-some-physiological-parameters-blood-picture-and-hemodynamic-parameters-blood-pressure-respiratory-assess-by-spo2-during-different-periods-in-laparoscopic-surgery-100552446","NCT06473194","This Study Assess Some Physiological Parameters, Blood Picture, and Hemodynamic Parameters, Blood Pressure, Respiratory Assess by SPO2, During Different Periods in Laparoscopic Surgery","Physiological and Biochemical Effects of Laparoscopic Anesthesia and Surgery","laparoscopy","Inclusion Criteria:\n\n1. elective abdominal surgery\n2. a healthy, fit person\n3. use of general anesthetics\n4. use of pneumoperitoneum and CO2 insufflation\n\nExclusion Criteria:\n\n1. emergency condition\n2. patient with cardiovascular disease",true,"20 Years","60 Years",{"count":232,"type":21},60,[24],"Laparoscopic surgery is widely used now. These benefits included many items, e.g. reducing post-operative pain, cosmetic the result was improved, and the patient also had more satisfaction for the patient and reduced hospital stay. This surgery involved insufflation of gas into the peritoneal cavity, producing pneumoperitoneum, and causing an increase in intra-abdominal pressure. The raised intraabdominal pressure of the pneumoperitoneum, the patient's position alteration, and the absorption of carbon dioxide into the abdomen have a direct effect on causing a change in physiology, especially in the cardiovascular and respiratory systems. These effects, as well as a direct effect of gas insufflation, may have significant effects on the patient especially if the patient has a comorbidity or is elderly.",[28,236],"Physiological Parameter","2024-06-21",{"date":239,"type":35},"2024-06-25",{"date":241,"type":21},"2024-10-01",{"date":243,"type":21},"2026-11-01",{"name":245,"class":42},"Mohammed Abdulhameed",{"id":247,"slug":248,"hasResults":11,"nctId":249,"briefTitle":250,"officialTitle":251,"acronym":252,"eligibilityCriteria":253,"healthyVolunteers":228,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":254,"targetDuration":203,"studyType":51,"phases":4,"briefSummary":256,"conditions":257,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":260,"lastUpdatePostDateStruct":261,"startDateStruct":263,"completionDateStruct":265,"leadSponsor":267,"locationsCount":71},"100506068","registry-of-anesthesia-and-perioperative-medicine-100506068","NCT05869578","Registry of Anesthesia and Perioperative Medicine","Registry of Patients Subjected to the Perioperative Care of the Anesthesia Service of Clinica Alemana of Santiago Chile","RAMP","Inclusion Criteria:\n\n* All individuals\n* Individuals agreeing to participate in the study by signing a consent\n\nExclusion Criteria:\n\n* The subjects who had insufficient data in their files",{"count":255,"type":21},10000,"To assess mortality and morbidity associated to anesthesia interventions",[258,259,124,88,28,89],"Perioperative Complication","Perioperative\u002FPostoperative Complications","2023-05-19",{"date":262,"type":35},"2023-05-22",{"date":264,"type":21},"2023-06-01",{"date":266,"type":21},"2045-01-01",{"name":268,"class":42},"Clinica Alemana de Santiago"]