[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anesthesia-intravenous\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anesthesia-intravenous":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,49,89,114],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100634556","the-impact-of-multiple-antihypertensive-therapy-on-post-induction-hypotension-burden-in-cardiac-surgery-patients-100634556",false,"NCT07541222","The Impact of Multiple Antihypertensive Therapy on Post-Induction Hypotension Burden in Cardiac Surgery Patients","The Impact of Multiple Antihypertensive Therapy on Post-Induction Hypotension Burden in Cardiac Surgery Patients: A Prospective Observational Cohort Study","Inclusion Criteria:\n\n* Adult patients aged 40 years and older\n* Undergoing elective cardiac surgery (e.g., isolated CABG, isolated valve surgery, or combined CABG+valve surgery via sternotomy)\n* Regular use of at least one antihypertensive medication for at least 4 weeks prior to the operation date\n* Voluntary participation and signed informed consent\n\nExclusion Criteria:\n\n* Emergency surgery\n* Preoperative shock or requirement for high-dose inotropic\u002Fvasopressor therapy\n* End-stage liver or kidney failure\n* Uncontrolled hypertension\n* Difficult intubation or prolonged induction process\n* Ejection fraction less than 35%","ALL","40 Years",{"count":19,"type":20},160,"ESTIMATED","OBSERVATIONAL","This study aims to investigate the impact of multiple preoperative antihyperstensive drug use on the burden of post-induction hypotension (PIH) in patients undergoing elective cardiac surgery. The researchers will observe whether the combination of different antihypertensive classes (such as ACE inhibitors, ARBs, beta-blockers, and calcium channel blockers) leads to a higher incidence and severity of blood pressure drops and increased need for vasoactive support during the period between anesthesia induction and surgical incision.",[24,25,26,27,28],"Hypotension on Induction","Cardiac Surgery","Antihypertensive Agents","Anesthesia, Intravenous","Hemodynamics",[30,31,32,33,34,35],"Post-induction hypotension","Cardiac surgery","Antihypertensive drugs","Hypotension burden","Mean arterial pressure","Anesthesia induction","RECRUITING","2026-05-05",{"date":39,"type":40},"2026-05-06","ACTUAL",{"date":42,"type":40},"2026-05-01",{"date":44,"type":20},"2026-12-01",{"name":46,"class":47},"Konya City Hospital","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":57,"minAge":4,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":88},"100612247","hemodynamic-effects-of-remimazolam-vs-propofol-during-robot-assisted-gynecologic-surgery-100612247","NCT07251101","Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery","A Randomized, Parallel, Open-label With Blinded Assessment Study Comparing Hemodynamic Profiles Between Remimazolam- and Propofol-based Total Intravenous Anesthesia in Patients Undergoing Robot-assisted Gynecologic Surgery","By_HD","Inclusion Criteria:\n\n* Female patients \\\u003C65 years of age\n* American Society of Anesthesiologists (ASA) physical status I-II\n* Scheduled to undergo robotic hysterectomy under general anesthesia\n\nExclusion Criteria:\n\n* Body mass index (BMI) \\> 35 kg\u002Fm²\n* Baseline hypotension (systolic blood pressure \\\u003C100 mmHg) or bradycardia (heart rate \\\u003C60 bpm)\n* History of ischemic heart disease or cardiac conduction block\n* Significant cardiopulmonary disease, including hypoxemia (SpO₂ \\\u003C90%), uncontrolled asthma, or chronic obstructive pulmonary disease (COPD)\n* Use of inhalational anesthetics during anesthesia\n* Conversion from robotic\u002Flaparoscopic surgery to open laparotomy","FEMALE","65 Years",{"count":60,"type":20},58,"INTERVENTIONAL",[63],"NA","This single-center study at CHA Ilsan Medical Center compares intraoperative hemodynamics between remimazolam- and propofol-based total intravenous anesthesia (TIVA) in patients undergoing robot-assisted gynecologic surgery requiring pneumoperitoneum and steep Trendelenburg positioning.",[27,66,67],"Hemodynamic Stability","Gynecologic Surgery",[69,70,71,72,73,74,75,76,77],"remimazolam","propofol","hemodynamics","laparoscopic surgery","general anesthesia","Trendelenburg position","pneumoperitoneum","gynecologic surgery","total intravenous anesthesia (TIVA)","NOT_YET_RECRUITING","2026-03-23",{"date":81,"type":40},"2026-03-27",{"date":83,"type":20},"2026-05-02",{"date":85,"type":20},"2027-12-30",{"name":87,"class":47},"Ilsan Cha hospital",2,{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":4,"eligibilityCriteria":95,"healthyVolunteers":11,"sex":16,"minAge":96,"maxAge":97,"enrollmentInfo":98,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":100,"conditions":101,"keywords":103,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":4},"100614146","respiratory-monitoring-in-supraglottic-airway-anesthesia-100614146","NCT07275801","Respiratory Monitoring in Supraglottic Airway Anesthesia","Continuous Breath Sound Monitoring Applied to Intravenous Anesthesia and Laryngeal Mask Airway Respiratory Monitoring: A Clinical Outcome Study","Inclusion Criteria:\n\n1. Scheduled to undergo elective breast surgery\n2. with anesthetic plan of intravenous anesthesia with supraglottic airway and spontaneous breathing\n\nExclusion Criteria:\n\n1. Emergency surgical cases\n2. with known or predicted difficult airways","18 Years","70 Years",{"count":99,"type":20},60,"This prospective observational study evaluates the feasibility and clinical utility of AI-enhanced continuous respiratory sound monitoring during intravenous anesthesia with supraglottic airway placement. With the increasing volume of surgical procedures requiring anesthesia, continuous respiratory monitoring has become essential. While standard monitors track anesthetic depth, end-tidal CO₂, oxygen saturation, and respiratory rate, real-time respiratory sound analysis offers additional clinical value. This study aims to verify whether continuous respiratory sound monitoring using the Airmod electronic stethoscope can detect respiratory depression and airway obstruction before hypoxemia develops, thereby improving the safety of supraglottic airway anesthesia. The protocol involves collecting 60 patients undergoing elective breast surgery with supraglottic airway anesthesia (inclusion criteria: age ≥18 years, BMI \\\u003C35; exclusion criteria: emergency cases, anticipated difficult airways, age \\\u003C18, BMI \\>35). During surgery, an electronic stethoscope patch provides continuous respiratory sound recording, converted to spectral data and analyzed by artificial intelligence, while standard anesthetic monitoring includes blood pressure, heart rate, bispectral index (BIS), SpO₂, and EtCO₂. Researchers document specific intraoperative events including airway positioning, oxygen flow adjustments, ventilation parameter changes, oxygen desaturation episodes, and abnormalities detected via auscultation. Anesthetic records, surgical notes, and recovery records are compiled in Excel format integrated with electronic medical records, with statistical analysis performed using SigmaPlot software. This research builds upon the Airmod electronic stethoscope approved for marketing in February 2025, aiming to establish device-specific respiratory monitoring protocols while enhancing patient safety during non-intubated anesthesia procedures.",[27,102],"Spontaneous Breathing",[104],"respiration, monitoring","2025-12-07",{"date":107,"type":40},"2025-12-10",{"date":109,"type":20},"2026-01-02",{"date":111,"type":20},"2026-08-31",{"name":113,"class":47},"National Taiwan University Hospital",{"id":115,"slug":116,"hasResults":11,"nctId":117,"briefTitle":118,"officialTitle":119,"acronym":4,"eligibilityCriteria":120,"healthyVolunteers":11,"sex":16,"minAge":96,"maxAge":121,"enrollmentInfo":122,"targetDuration":4,"studyType":61,"phases":124,"briefSummary":125,"conditions":126,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":88},"100534305","remifentanil-effect-on-burst-suppression-ratio-100534305","NCT06237101","Remifentanil Effect on Burst Suppression Ratio","Influence of Variable Plasma Concentrations of Remifentanil on Burst Suppression (BS) Event Rate in Electroencephalographic (EEG) Recordings of Human Subjects Undergoing Total Intravenous General Anesthesia (TIVA) Under Propofol","Inclusion Criteria:\n\n* American Society of Anesthesiology I or II\n* Elective surgery of low or intermediate risk\n\nExclusion Criteria:\n\n* Neurological disease\n* Psychiatric disease\n* Use of psychoactive drugs or opioids\n* Altered basal state of consciousness\n* Allergy to propofol\n* Body mass index \\> 35 kg\u002Fm2\n* Pre-existing renal, cardiac and\u002For hepatic dysfunction\n* Patient's refusal to participate","60 Years",{"count":123,"type":20},20,[63],"The goal of this clinical trial is to determine whether remifentanil has a facilitating effect on the generation of burst suppression by propofol in adult patients (18-60 years) candidates for elective surgery who require remifentanil and American Society of Anesthesiology (ASA) classification I or II. The main question it aims to answer are:\n\n• To determine whether remifentanil has a facilitating effect on the generation of burst suppression by propofol.\n\nParticipants will undergo general anesthesia with remifentanil and propofol sequentially. After loss of consciousness, remifentanil will be adjusted to a medium or high concentration randomly and it will be determined at what concentration of propofol the burst suppressions are generated.\n\nThen, the concentrations of propofol that generate burst suppression associated with either a medium or high concentration of remifentanil will be compared.",[27,127,128],"Electroencephalography","Burst Suppression","2025-11-17",{"date":131,"type":40},"2025-11-20",{"date":133,"type":40},"2024-03-01",{"date":135,"type":20},"2026-09-30",{"name":137,"class":47},"University of Chile"]