[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anesthesia-recovery-period\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anesthesia-recovery-period":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100618529","site-of-tracheal-extubation-and-operating-room-efficiency-during-robot-assisted-surgery-100618529",false,"NCT07332806","Site of Tracheal Extubation and Operating Room Efficiency During Robot-assisted Surgery","Impact of Site of Tracheal Extubation on Operating Room Efficiency During Robot-assisted Surgery: a Randomized Trial","Inclusion Criteria:\n\n1. Aged ≥18 years;\n2. Scheduled to undergo elective robot-assisted laparoscopic surgery under general anesthesia;\n3. Expected tracheal extubation during daytime working hours (before 4:00 PM).\n\nExclusion Criteria:\n\n1. Refuse to participate in the study;\n2. Morbid obesity (body mass index ≥35 kg\u002Fm²);\n3. Preoperatively diagnosed obstructive sleep apnea, or patients with a STOP-Bang score ≥3 in combination with serum bicarbonate (HCO₃-) ≥28 mmol\u002FL;\n4. Patients at high risk of difficult airway (anticipated difficult intubation and\u002For extubation during preoperative assessment);\n5. Preexisting sick sinus syndrome, severe sinus bradycardia (heart rate \\\u003C 50 beats\u002Fmin), or second-degree or higher atrioventricular block without pacemaker implantation; congenital heart disease with any type of arrhythmia; or other severe cardiovascular diseases with New York Heart Association (NYHA) functional class ≥III;\n6. Significant pulmonary function impairment (FEV₁\u002FFVC ratio \\\u003C 70%, and total lung capacity \\[TLC\\] and vital capacity \\[VC\\] \\\u003C 80% of predicted values);\n7. Severe hepatic dysfunction (Child-Pugh class C); severe renal dysfunction (estimated glomerular filtration rate \\\u003C 30 mL\u002Fmin\u002F1.73 m²); or American Society of Anesthesiologists (ASA) physical status classification ≥IV;\n8. Preoperative diagnoses of schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis;\n9. Inability to communicate due to coma, severe dementia, or language impairment;\n10. Planned postoperative admission to the intensive care unit;\n11. Any other conditions that are deemed for study participation.","ALL","18 Years",{"count":19,"type":20},218,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to evaluate the impact of different extubation strategy on the occupancy time of operating room (OR) and the incidence of adverse events and quality of recovery after robotic-assisted surgery. The investigators hypothesize that extubation in the post-anesthesia care unit (PACU) may reduce OR occupancy time without increasing adverse events or worsening quality of recovery early after robotic-assisted surgery. This strategy may enhance perioperative efficiency while maintaining clinical safety.",[26,27,28,29,30],"Robotic Surgical Procedures","Airway Extubation","Operating Rooms","Anesthesia Recovery Period","Postoperative Complications",[26,27,28,29,30],"RECRUITING","2026-01-13",{"date":35,"type":36},"2026-01-15","ACTUAL",{"date":38,"type":36},"2026-01-12",{"date":40,"type":20},"2026-04",{"name":42,"class":43},"Peking University First Hospital","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":62,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":44},"100585667","guiding-opioid-administration-by-nociception-level-index-nol-in-patients-with-regional-anesthesia-100585667","NCT06905340","Guiding Opioid Administration by Nociception Level Index (NOL) in Patients With Regional Anesthesia","Nociception Level Index-Guided Intraoperative Opioids in Patients With a Combination of General and Regional Anesthesia","NORA","Inclusion Criteria:\n\n\\- Patients undergoing elective trauma or orthopedic surgery with a combination of general and regional anesthesia\n\nExclusion Criteria:\n\n* Preexisting therapy with cardiac glycosides or pacemakers\n* Cardiac arrhythmia (atrial fibrillation, atrioventricular block \\> I°)\n* Chronic opioid misuse\n* Intraoperative treatment with ketamine, beta-adrenergic agonists, or clonidine\n* Serious peripheral or cardiac autonomic neuropathy\n* Inability to specify the postoperative pain level\n* Postoperative treatment in an ICU",{"count":54,"type":20},240,[23],"General anesthesia consists of a combination of hypnotic drugs to achieve unconsciousness and opioid analgesics to ensure antinociception. An alternative approach to the intraoperative administration of high-potency opioids to achieve antinociception during surgery is combining general anesthesia with regional anesthesia. Modern general anesthesia aims to avoid an overdose of opioid analgesics and reduce side effects of opioid administration. Quality and safety of general anesthesia are of major clinical importance and can be improved by adjusting the opioid analgesics to the optimal individual dose needed.\n\nIn current clinical practice, opioid dosage is usually determined by clinical judgment. However, different monitoring devices estimating the effect of nociception during unconsciousness have become commercially available. One of the most recent commercially available nociception indices is the Nociception Level Index (NOL). Until today, there is conflicting evidence on whether guiding sufentanil administration by NOL monitoring, which is the intended use of the nociception index, affects postoperative pain level in the postanesthesia care unit (PACU), the amount of postoperatively administered opioids, and the quality of postoperative recovery in patients with a combination of general and regional anesthesia. This study aims to investigate the clinical performance of intraoperative NOL monitoring and determine whether guiding sufentanil administration by NOL monitoring - compared to routine care - reduces either postoperative pain level in the PACU, postoperative opioid consumption in the PACU or postoperative opioid consumption in the first 24 hours after the operation in patients having trauma and orthopedic surgery with combined general and regional anesthesia.",[58,59,60,29,61],"Nociceptive Pain","Pain, Postoperative","Analgesia, Postoperative","Opioid Use",[63,64,65,66],"General anesthesia","Regional anesthesia","Analgesia Monitoring","Opioids","2025-06-04",{"date":69,"type":36},"2025-06-08",{"date":71,"type":36},"2025-05-12",{"date":73,"type":20},"2026-01",{"name":75,"class":43},"Universitätsklinikum Hamburg-Eppendorf",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":21,"phases":87,"briefSummary":88,"conditions":89,"keywords":4,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":4},"100584419","comparing-effect-of-opioid-sparing-versus-conventional-anesthesia-on-quality-of-recovery-after-emergency-laparotomy-100584419","NCT06889090","Comparing Effect of Opioid-sparing Versus Conventional Anesthesia on Quality of Recovery After Emergency Laparotomy","Comparing Effect of Opioid-sparing Versus Conventional Anesthesia on Quality of Recovery After Emergency Laparotomy: a Randomized Controlled Trial","O-S Anesthesia","Inclusion Criteria:\n\n* Adult patients (18-65 years)\n* ASA I-III undergoing emergency laparotomy with midline incision.\n\nExclusion Criteria:\n\n* Severe cardiac morbidities (impaired contractility with ejection fraction \\\u003C 45%, heart block, arrhythmias, tight valvular lesions) and patients on beta-blockers\n* Patients on vasopressor infusion, patients with high shock index (heart rate \u002F systolic blood pressure \\>1)\n* Body mass index \\\u003C18 or \\> 35 Kg\u002Fm2,\n\n  * Pregnant or lactating women,","65 Years",{"count":86,"type":20},120,[23],"Aim of the Work The investigators aim to compare lidocaine-based anesthesia versus conventional anesthesia in the presence of multimodal analgesia protocol in terms of early quality of recovery and analgesic efficacy.\n\nObjectives To compare quality of recovery using the Quality of recovery-15 (QoR-15) score between lidocaine-based anesthesia in relation to conventional anesthesia in patients undergoing emergency laparotomy.\n\nHypothesis the investigators hypothesize that lidocaine-based regimen would be effective in reducing opioid use and provide superior quality of recovery compared to conventional opioid-routine anesthesia in emergency laparotomy.",[29],"NOT_YET_RECRUITING","2025-03-21",{"date":93,"type":36},"2025-03-26",{"date":95,"type":20},"2025-04-20",{"date":97,"type":20},"2026-05-12",{"name":99,"class":43},"Cairo University"]