[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"aneurysm-abdominal\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:aneurysm-abdominal":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,45,90,117],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":4},"100616972","occurrence-of-abdominal-aortic-aneurysms-in-patients-with-aneurysmal-subarachnoid-hemorrhage-100616972",false,"NCT07312565","Occurrence of Abdominal Aortic Aneurysms in Patients With Aneurysmal Subarachnoid Hemorrhage","The Occurrence of Abdominal Aortic Aneurysms in Patients With Ruptured Intracranial Aneurysms","TRACE-aSAH","Inclusion Criteria:\n\nIn order to be eligible to participate in this study, a participant must meet all of the following criteria:\n\n* Patient is a study subject of the trial: Study on Prognosis of Acutely RupTured Aneurysms (SPARTA)(12)\n* Inclusion at least one year after aSAH\n* Written informed consent\n\nBy being a study subject of the SPARTA trial, the following criteria are applicable:\n\n* Confirmed diagnosis of SAH on CT-scan or lumbar puncture (in the presence of a negative CT-scan)\n* IA related SAH as confirmed with radiological imaging\n* Age 18 years or older at presentation\n* Written informed consent for the SPARTA-trial\n\nExclusion Criteria:\n\nA potential participant who meets any of the following criteria will be excluded from participation in this study:\n\n* Patient is not a study subject of the SPARTA trial\n* Patient has Loeys-Dietz-, Marfan- or Ehlers-Danlos syndrome","ALL","18 Years",{"count":20,"type":21},233,"ESTIMATED","OBSERVATIONAL","Rationale: Aneurysms of different types are known to be associated. In literature, concurrence of intracranial- and aortic aneurysms is described. Screening for aortic aneurysms (AA) in patients with intracranial aneurysms (IA) or aneurysmal subarachnoid haemorrhage (aSAH) could be cost-effective and of significant importance to decrease morbidity and mortality. The available literature on the association between the two types of aneurysms is sparse and in general of poor methodological quality. This protocol presents a study to more adequately evaluate the association between IA and AA.\n\nObjective: To investigate the occurrence of abdominal aortic aneurysms (AAA) in patients who experienced aSAH.\n\nStudy design: This single cohort prospective study will include patients who experienced aSAH. The study participants will receive an abdominal ultrasound of the aorta to detect an AAA.\n\nStudy population: aSAH patients from a prospective cohort trial in the Netherlands.\n\nMain study parameters\u002Fendpoints: The primary outcome, which will be investigated in the here above described study population, is the number of AAA detected on abdominal ultrasound.\n\nNature and extent of the burden and risks associated with participation, benefit and group relatedness: Patients will not receive an intervention, but only a diagnostic imaging without radiation. The burden associated with this study are considered minimal and the risks negligible. An abdominal ultrasound is a non-invasive diagnostic method with no risks for the participant. The only possible existing burden to the participant is travel and appointment time with a risk of detecting an abdominal aortic aneurysm or other (occult) intra-abdominal pathologies. When an aneurysm, sub-aneurysm or other intra-abdominal pathology is detected, surveillance or treatment according to standard of care and guidelines will follow.",[25,26],"Aneurysm Abdominal","Cerebral Aneurysm Ruptured",[28,29,30,31,32],"abdominal aortic aneurysm","aneurysmal subarachnoid hemorrhage","ruptured intracranial aneurysm","prospective single cohort study","ultrasound","NOT_YET_RECRUITING","2026-04-09",{"date":36,"type":37},"2026-04-14","ACTUAL",{"date":39,"type":21},"2026-06-01",{"date":41,"type":21},"2026-12-01",{"name":43,"class":44},"Leiden University Medical Center","OTHER",{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":73,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":89},"100586678","prophylactic-suture-line-sealing-with-nex-glue-r-eco-in-cardiac-and-vascular-surgery-100586678","NCT06918496","Prophylactic Suture Line Sealing With NE'X Glue R-eco in Cardiac and Vascular Surgery","A Prospective ClinicaL investigatiOn Evaluating Prophylactic Sealing of sUture Lines Using the NE'X Glue R-eco Surgical AdhesivE in Cardiac and (Cardio)Vascular Anastomotic Repair Procedures","CLOSURE","Inclusion Criteria:\n\n* Patient ≥ 18 years of age at study entry.\n* Patient is scheduled for open procedures for surgical placement of a prosthetic or biologic graft (patch) or an allograft for cardiac and (cardio)vascular anastomosis repair. Emergency, transplantation and minimally invasive procedures are excluded. Patients receiving long-term anticoagulation, including antiplatelet agent, are included. Choice of graft is at the discretion of the surgeon.\n* Patient is willing and able to be contacted for up to 3 months (± 14 days) follow-up.\n* Patient or legal representative and investigator signed and dated the informed consent form prior to the index-procedure.\n\nExclusion Criteria:\n\n* Patient has a known hypersensitivity, contraindication, or allergic reaction to albumin or glutaraldehyde.\n* Patient has a history of bleeding diathesis or coagulopathy.\n* Presence of active infection or contamination in the to be grafted area or the vicinity.\n* Known vasculitis in the to be grafted area.\n* Patient takes immune suppressive medication like prednisone resulting in weakening of the vessel wall.\n* Patient is refusing blood transfusion.\n* Patient or legal representative is unable \u002F unwilling to provide informed consent.\n* Patient is unable to comply with the protocol or proposed follow-up visits.\n* Female patient is pregnant, lactating, or planning pregnancy during the clinical investigation.\n* Female participants of childbearing age must agree to use safe contraception (e.g., intrauterine devices, hormonal contraceptives: contraceptive pills, implants, transdermal patches hormonal vaginal devices, injections with prolonged release, abstinence).\n* Patients who are currently enrolled in another clinical study, or have recently participated in a clinical study, that could potentially interfere with the outcomes or introduce bias into the results of the current study (as determined by the investigator). This includes studies involving investigational drugs, medical devices, or other interventions that could impact the safety, efficacy, or scientific integrity of this study.",{"count":54,"type":21},60,"INTERVENTIONAL",[57],"NA","This clinical study aims to evaluate the effectiveness and safety of using NE'X Glue R-eco to seal suture lines. The adhesive will be applied to reduce the risk of suture line bleeding in cardiac or vascular repair surgeries, a prosthetic or biologic graft, patch, or allograft.\n\nThe effectiveness of the adhesive will be assessed after restoring blood flow.",[60,61,62,63,64,65,25,66,67,68,69,70,71,72],"Aortic Aneurysm","Aortic Aneurysm Abdominal","Valve Stenoses, Aortic","Valve Regurgitation, Mitral","Valve Regurgitation, Tricuspid","Aneurysm of Ascending Aorta","Artery Diseases, Peripheral","Ventricular Aneurysm","Coronary Artery Disease","Valve Aortic Regurgitation","Aortic Aneurysms Arch","Aortic Aneurysms Descending","Aortic Aneurysms Thoracoabdominal",[74,75,76,77,78],"prophylactic sealing of suture lines","Surgical glue","cardiac and (cardio)vascular anastomotic repair procedures","grafts","NE'X Glue R-eco surgical adhesive","2025-04-08",{"date":81,"type":37},"2025-04-09",{"date":83,"type":21},"2025-06-30",{"date":85,"type":21},"2026-03-31",{"name":87,"class":88},"Grena Biomed Limited","INDUSTRY",2,{"id":91,"slug":92,"hasResults":11,"nctId":93,"briefTitle":94,"officialTitle":94,"acronym":95,"eligibilityCriteria":96,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":97,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":99,"conditions":100,"keywords":102,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":116},"100541093","italian-multicentric-study-on-the-treatment-of-visceral-aneurysms-with-the-flow-diversion-stent-derivo-peripher-and-derivo-2-100541093","NCT06325371","Italian Multicentric Study on the Treatment of Visceral Aneurysms With the Flow Diversion Stent Derivo Peripher and Derivo 2","DEDICATE","Inclusion criteria:\n\n* \\>18 years old\n* Visceral artery aneurysms, evaluated with computed tomography angiography-CTA- withindication for treatment according to 2020 SVS and 2024 SICVE\u002FSIRM and 2024 CIRSE guidelines. Specifically:\n\n  * Renal artery: \\>2 cm if fusiform morphology or all dimensions if sacculary or bifurcation morphology, if in fertile women or in hypertensive patients with renal stenosis\n  * Splenic artery: if \\>2 cm, or all dimensions in fertile women.\n  * Celiac tripod: if \\>2 cm.\n  * Hepatic artery: if \\>2 cm or growth greater than 0.5 cm\u002Fyear.\n  * Superior mesenteric artery, gastric or gastroepiploic artery, pancreaticoduodenal or gastroduodenal arteries, colic arteries, jejunal arteries, and ileal arteries: any size\n* anatomical characteristics compatible with the stent DED Instruction for Use (IFU). Specifically:\n\n  * the stent diameter should match the largest diameter of either the proximal or distal vessel of the aneurysm with an oversizing of 1-2 mm according to IFU.\n  * the stent length must allow for adequate proximal and distal landing, covering the neck of the aneurysm to 2.5 times the vessel's internal diameter and no less than 15 mm.\n* proper adherence to the anticoagulant and antiplatelet pharmacological protocol for the peri-procedural and post-procedural periods. Specifically:\n\n  * all patients should begin dual antiplatelet therapy (DAPT) before surgery (for at least 3 days before the procedure or with a loading dose pre-procedurally).\n  * all patients receive systemic anticoagulation during the procedure (Heparin 70 IU\u002Fkg to achieve an Activated Clot Time (ACT) \\> 250 s).\n  * after the procedure, the patient should continue DAPT (e.g., ASA 100 mg daily and Clopidogrel 75 mg daily) for at least 1 month, then continue with single antiplatelet therapy (e.g., ASA 100 mg) indefinitely.\n\nExclusion Criteria:\n\n* patients who are hemodynamically unstable or show CT signs of rupture or contained rupture of visceral aneurysm\n* pregnant or breastfeeding women\n* life expectancy less than 2 years",{"count":98,"type":21},100,"This is a multicentric voluntary observational study with a retrospective evaluation of prospectively collected data concerning the treatment of visceral aneurysms with flow diversion stent Derivo Peripher and Derivo 2 (DED, Acandis GmbH) Follow-up will include clinical and radiological (CT) evaluation at least 12 months after the intervention.\n\nThe enrollment period will be of 65 months (01\u002Fjan\u002F2020-30\u002Fjun\u002F2025). Sample size will be of 100 patients.",[25,101],"Arterial Aneurysm",[103,104,105],"flow diverter","visceral aneurysm","stenting","RECRUITING","2025-02-17",{"date":109,"type":37},"2025-02-18",{"date":111,"type":37},"2024-11-20",{"date":113,"type":21},"2026-06-30",{"name":115,"class":44},"University of Turin, Italy",1,{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":121,"acronym":122,"eligibilityCriteria":123,"healthyVolunteers":11,"sex":17,"minAge":124,"maxAge":125,"enrollmentInfo":126,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":128,"conditions":129,"keywords":131,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":142},"100531943","developing-trustworthy-artificial-intelligence-ai-driven-tools-to-predict-vascular-disease-risk-and-progression-100531943","NCT06206369","Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression","VASCULAIDRETRO","Inclusion Criteria:\n\n* Males and females, 40-90 years old, with an AAA \\>3cm. This includes patients with infrarenal, juxtarenal, suprarenal, iliac (defined as 1.5x its normal diameter) aneurysms, as well as mycotic aneurysms. Patients that have had interventions or ruptures will also be included\n* Males and females, 40-90 years old, all PAD patients (Fontaine stages 1,2,3, and 4).\n\nExclusion Criteria:\n\n* Patients with an ascending, thoracic, thoracoabdominal (type 1-3) aneurysm.","40 Years","90 Years",{"count":127,"type":21},11000,"The VASCULAID-RETRO study, within the broader VASCULAID project, aims to create artificial intelligence (AI) algorithms that can predict cardiovascular events and the progression of abdominal aortic aneurysm (AAA) and peripheral arterial disease (PAD). The study plans to gather and analyze data from at least 5000 AAA and 6000 PAD patients, combining existing cohorts and retrospectively collected data. During this project, AI tools will be developed to perform automatic anatomical segmentation and analyses on multimodal imaging. AI prediction algorithms will be developed based on multisource data (imaging, medical history, -omics).",[25,130],"Peripheral Arterial Disease",[132],"Artificial Intelligence, Prediction models, Image analysis, Abdominal Aortic Aneurysms, Peripheral Arterial Disease","2024-01-04",{"date":135,"type":37},"2024-01-16",{"date":137,"type":37},"2023-10-31",{"date":139,"type":21},"2029-05-01",{"name":141,"class":44},"Amsterdam UMC, location VUmc",6]