[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ankle-instability\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ankle-instability":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,70,109],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100644057","different-pressure-tissue-flossing-combined-with-exercise-for-chronic-ankle-instability-100644057",false,"NCT07667816","Different Pressure Tissue Flossing Combined With Exercise for Chronic Ankle Instability","Effects of Different Tissue Flossing Pressures Combined With Exercise Training on Ankle Function in Patients With Chronic Ankle Instability: A Three-Arm Randomized Controlled Trial","CAI-FLOSS","Inclusion Criteria:\n\n* Young adults aged 18 to 30 years.\n* History of at least one recurrent ankle sprain or repeated episodes of ankle giving way in the affected limb.\n* Subjective ankle instability, with or without pain, swelling, or activity limitation.\n* Reduced balance ability, movement ability, or foot and ankle function on screening assessment.\n* Symptoms lasting at least 6 months.\n* No recent structured ankle rehabilitation before enrollment.\n* No plan for vigorous additional exercise during the intervention period.\n* Willing to participate and able to provide informed consent.\n\nExclusion Criteria:\n\n* Latex allergy or intolerance to floss band material.\n* Previous ankle dislocation, fracture, complete ligament rupture, or other severe structural injury.\n* Most recent ankle sprain within 1 month before enrollment.\n* Recent ankle surgery or acute ankle injury.\n* Receipt of other ankle-related treatment, rehabilitation, or additional training during the study period.\n* Diabetes, hyperlipidemia, or other conditions that may affect vascular status.\n* Neurological disease, major musculoskeletal disease, vestibular disorder, visual disorder, or other lower-limb conditions that could affect assessment.\n* Determined by the study physician or investigator to be unsuitable for participation.","ALL","18 Years","30 Years",{"count":21,"type":22},48,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study will evaluate whether tissue flossing with different pressure levels, when combined with exercise training, improves ankle function in young adults with chronic ankle instability. Forty-eight participants will be randomly assigned to one of three groups: a control exercise group, a 150 mmHg tissue flossing plus exercise group, or a 200 mmHg tissue flossing plus exercise group. All groups will complete the same 6-week rehabilitation program, three times per week. Outcomes will be assessed at baseline and after the intervention, and long-term follow-up data will also be collected.",[28,29],"Chronic Ankle Instability","Ankle Instability",[31,32,28,33,34],"Tissue Flossing","Floss Band","Ankle Rehabilitation","Exercise Therapy","NOT_YET_RECRUITING","2026-06-21",{"date":38,"type":39},"2026-06-25","ACTUAL",{"date":41,"type":22},"2026-07",{"date":43,"type":22},"2027-05",{"name":45,"class":46},"Chengdu Sport University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":66,"leadSponsor":68,"locationsCount":47},"100621922","acute-effect-of-graded-motor-imagery-on-ankle-rehabilitation-a-pilot-study-100621922","NCT07376915","Acute Effect of Graded Motor Imagery on Ankle Rehabilitation: A Pilot Study","The Acute Effect of Graded Motor Imagery-Based Mental Preparation on Ankle Rehabilitation: A Pilot Clinical Study","Inclusion Criteria:\n\n* Aged between 18 and 40 years.\n* Diagnosed with chronic ankle instability (CAIT ≤ 24).\n* History of an acute ankle sprain occurring more than 3 months prior to enrollment.\n* Has not received ankle rehabilitation treatment.\n* Voluntarily participated in this study\n\nExclusion Criteria:\n\n* Vestibular or neurological disorders\n* Other lower extremity injuries\n* History of surgery","40 Years",{"count":21,"type":22},[25],"The primary aim of this study is to evaluate the immediate and short-term effects of the Graded Motor Imagery (GMI) method on individuals with chronic ankle instability (CAI). In this context, the effects of the Graded Motor Imagery intervention on pain level, muscle stiffness, muscle strength, functional performance, and subjective instability level will be investigated. Additionally, these effects will be comparatively analyzed with an age- and sex-matched control group consisting of healthy individuals.",[29,60],"Healthy Controls","RECRUITING","2026-02-09",{"date":64,"type":39},"2026-02-11",{"date":62,"type":39},{"date":67,"type":22},"2026-06-09",{"name":69,"class":46},"Istanbul University - Cerrahpasa",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":79,"targetDuration":81,"studyType":82,"phases":4,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":47},"100607423","french-ankle-ligament-surgery-cohort-study-100607423","NCT07188363","French Ankle Ligament Surgery Cohort Study","Prospective Follow-up Study of Patients Undergoing Ankle Ligament Surgery","AnkleCDS","Inclusion Criteria:\n\n* Retensioning, ankle ligament reconstruction or syndesmosis repair surgery\n\nExclusion Criteria:\n\n* Patient refusal","7 Years",{"count":80,"type":22},5000,"20 Years","OBSERVATIONAL","This 20-year cohort study foolows patients after ankle ligament reconstruction surgery to evaluate re-rupture rates, long term functional outcomes, return to sport rates ans complications? The goal is to provide insights into the procedure's durability and effectiveness to enhance patient care.",[85,86,29,87],"Ankle (Ligaments); Instability (Old Injury)","Ankle Ligament Rupture","Syndesmotic Injury",[89,90,91,92,93,94,95,96,97,98,99],"ankle","ligamentoplasty","surgery","orthopedy","FHL","rupture","ligament","syndesmosis","instability","retensioning","flexor hallucic longus","2026-01-03",{"date":102,"type":39},"2026-01-06",{"date":104,"type":39},"2022-09-01",{"date":106,"type":22},"2062-08-30",{"name":108,"class":46},"Chirurgie Du Sport",{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":113,"acronym":114,"eligibilityCriteria":115,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":116,"targetDuration":4,"studyType":23,"phases":118,"briefSummary":119,"conditions":120,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":47},"100588730","long-term-evaluation-of-sports-activity-in-patients-whose-ankle-was-treated-by-anatomical-reconstruction-or-arthroscopic-repair-following-chronic-lateral-instability-100588730","NCT06945198","Long-term Evaluation of Sports Activity in Patients Whose Ankle Was Treated by Anatomical Reconstruction or Arthroscopic Repair Following Chronic Lateral Instability","ANKLE STAB","Inclusion Criteria:\n\n* Patient, male or female, aged ≥ 18 years\n* Patient with chronic ankle instability defined by:\n* A history of trauma including a severe ankle sprain.\n* Clinical symptoms persisting for at least 3 months at the time of inclusion: pain, swelling, sensation of 'giving way', sensation of instability, recurrent sprains; Clinical tests (drawer test, varus provocation test) confirming grade III laxity; Imaging results (MRI) confirming clinically suspected ligament damage.\n* Patient affiliated to or benefiting from a social security scheme\n* French-speaking patient who has signed an informed consent form\n\nExclusion Criteria:\n\n* Patient with deltoid ligament injury, severe fracture or open trauma\n* Patient with insufficient ligament remnant and\u002For in too poor a condition to allow Broström-type repair.\n* Patient with a symptomatic osteochondral lesion\n* Patient with ankle hyperlaxity (Beighton score \\> 3)\n* Patient with early ankle arthropathy (Takakura arthritis classification ≥ stage 3)\n* Patient with neuromuscular disorders, systemic inflammatory disorders or tumours.\n* Patient requiring surgery on both ankles\n* Patients with a bony deformity of the ankle or foot on the affected side;\n* Patients with professional athlete status\n* Patient already included in another study\n* Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision",{"count":117,"type":22},200,[25],"The goal of this clinical trial is to compare at 5 years the sporting activity of patients whose ankle had been treated by reconstruction or repair following chronic lateral instability. The main question it aims to answer is:\n\nWhat is the long-term sporting activity status of patients whose ankle had been treated by reconstruction or repair following chronic lateral instability ?\n\nParticipants will visit the clinic once every year during 5 years for clinical checkup.",[29],"2025-09-26",{"date":123,"type":39},"2025-09-29",{"date":125,"type":22},"2025-10-01",{"date":127,"type":22},"2031-12-31",{"name":129,"class":46},"GCS Ramsay Santé pour l'Enseignement et la Recherche"]