[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ankle-sprain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ankle-sprain":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,51,74,101,128,152,181,206,227,252],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100638420","ankle-vs-hip-vs-combined-strengthening-in-chronic-ankle-instability-100638420",false,"NCT07606534","Ankle vs. Hip vs. Combined Strengthening in Chronic Ankle Instability","Ankle vs. Hip vs. Combined Strengthening in Chronic Ankle Instability: A Randomized Controlled Trial","SHAC","Inclusion Criteria:\n\n* Have a history of at least one major ankle sprain that occurred at least 12 months prior to enrolment in the study, was associated with inflammatory symptoms (pain, swelling, etc), created at least one interrupted day of desired physical activity.\n* Have had at least two episodes of feeling like an \"unstable\" ankle in the six months preceding the study.\n* The Cumberland Ankle Instability Tool (CAIT) with a score of less than 24.\n* The Foot and Ankle Ability Measure (FAAM) Sport scale with a score below 80%.\n* Between 18 and 35 years old\n* Must be able to understand the study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Have had a recent injury of less than three months prior to enrolment in the study.\n* A history of surgery on the musculoskeletal structures of the lower limbs.\n* Have a history of fracture of one of the lower limbs requiring realignment.\n* Being diagnosed with a neuromuscular disease.\n* The appearance of swelling or pain in the lower limb during the experiment.","ALL","18 Years","35 Years",{"count":21,"type":22},45,"ESTIMATED","INTERVENTIONAL",[25],"NA","Chronic ankle instability (CAI) is a common condition that can develop after a lateral ankle sprain. Up to 40% of people who sprain their ankle experience a recurrence within a year, and as many as 30% develop persistent symptoms such as ankle \"giving way,\" weakness, or instability. These symptoms can limit daily activities, sports participation, and increase the risk of future sprains. Muscle weakness in both the ankle and hip has been identified as an important factor contributing to CAI. Strengthening these muscles may therefore help improve stability and function.\n\nThe SHAC study is a randomized controlled trial designed to compare three different strengthening programs in people with chronic ankle instability: (1) an ankle-focused strengthening program, (2) a hip-focused strengthening program, and (3) a combined ankle-hip strengthening program. The goal is to determine which approach leads to the greatest improvement in functional ability, muscle strength, balance, and ankle mobility.\n\nA total of 45 participants aged 18 to 35 years with documented chronic ankle instability will be recruited from local sports clubs and the University of Liège. All participants must have a history of at least one ankle sprain that occurred more than 12 months before entering the study, report episodes of ankle instability in the previous six months, and meet specific questionnaire criteria (CAIT \\\u003C 24 and FAAM Sport \\\u003C 80%). People with recent injuries, previous lower-limb surgery, fractures requiring realignment, neuromuscular conditions, or current pain or swelling will not be able to participate.\n\nAfter the first assessment (T1), participants will be randomly assigned to one of the three groups. Each intervention lasts four weeks and includes three supervised sessions per week. All strengthening exercises are isometric, performed using a handheld dynamometer to measure force accurately. The ankle program includes plantarflexion, dorsiflexion, inversion, and eversion exercises. The hip program includes clamshells, hip external rotation, abduction, and extension. The combined group alternates between hip and ankle exercises. A warm-up and standardized familiarization are performed before each session.\n\nAll participants will attend two additional assessment sessions: one immediately after the four-week program (T2) and one at a later follow-up time point (T3). During each visit, they will complete functional questionnaires, report their sports participation, and undergo several strength and performance tests. These include hip and ankle muscle strength measurements using a dynamometer, the Heel Rise Test, the modified Y-Balance Test, the Side Hop Test, and a dorsiflexion mobility test.\n\nThe study aims to identify whether one of the strengthening approaches leads to better functional outcomes for individuals with chronic ankle instability. Understanding these effects may help clinicians design more effective rehabilitation programs for people recovering from ankle sprains and for those experiencing ongoing instability.\n\nParticipant data will be kept confidential and stored securely in anonymized form for 20 years. Participation is voluntary, and individuals may withdraw at any time without consequences. Results will be presented anonymously in scientific publications and conferences.",[28,29],"Chronic Ankle Instability, CAI","Ankle Sprain",[31,32,33,34,35,36,37],"chronic ankle instability","Ankle strengthening","Hip strengthening","Isometric exercise","Physiotherapy","Rehabilitation","Randomized controlled trial","RECRUITING","2026-05-18",{"date":41,"type":42},"2026-05-26","ACTUAL",{"date":44,"type":42},"2026-03-02",{"date":46,"type":22},"2027-09",{"name":48,"class":49},"University of Liege","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":50},"100585048","comparison-of-mbr--suture-tape-and-mbr-for-clai--a-prospective-cohort-study-100585048","NCT06897293","Comparison of MBR + Suture Tape and MBR for CLAI : A Prospective Cohort Study","Comparison of Modified Broström Repair + Suture Tape and Modified Broström Repair for Chronic Lateral Ankle Instability : A Prospective Cohort Study","Inclusion Criteria:\n\n* Clinical diagnosis of lateral ankle instability\n* Beighton score ≥4\n* Age with 18 to 60 years\n\nExclusion Criteria:\n\n* Patients with an acute or subacute ankle injury\n* Injury of the deltoid ligament\n* Alignment of lower extremity greater than 5 degrees\n* Fractures of the lower extremity\n* Stage III or IV osteoarthritis\n* Patients who refused to participate in the study","15 Years","55 Years",{"count":61,"type":22},86,"OBSERVATIONAL","GJL is a risk factor for postoperative recurrent instability following an MBR for CLAI. Additional suture tape augmentation has been suggested to provide more strength and stability. However, the outcomes of the MBP with suture tape augmentation were unknown, which requires further exploration.",[29,65],"Hypermobility, Joint",{"date":67,"type":42},"2026-05-20",{"date":69,"type":42},"2021-06-01",{"date":71,"type":22},"2026-06-01",{"name":73,"class":49},"Peking University Third Hospital",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":23,"phases":84,"briefSummary":85,"conditions":86,"keywords":87,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":50},"100594921","semiconductor-embedded-socks-for-ankle-sprains-100594921","NCT07025733","Semiconductor Embedded Socks for Ankle Sprains","Clinical Outcomes Related to Treatment of Ankle Injury Using Semiconductor Embedded Therapeutic Socks: A Randomized, Prospective, Double Blinded Clinical Study","Inclusion Criteria:\n\n* Ankle sprain, avulsion fracture, distal fibular fracture\n* Pain for at least 1 day\n* Patients 18-69 years old\n\nExclusion Criteria:\n\n* Patients with neurological conditions\n* Patients with prior surgical treatment of lower limb injury\n* Patients with chronic pain conditions\n* Patient with auto-immune or auto-inflammatory disease\n* Patients with tobacco use in last 90 days\n* Patients with history of metabolic disorders\n* Patients with open wound at area of application\n* Patients with acute or systemic infection","70 Years",{"count":83,"type":22},100,[25],"The goal of this clinical trial is to determine if semiconductor fabric embedded in socks can improve healing after non operative ankle sprains. The main questions it aims to answer are:\n\n1. How does semiconductor embedded sock effect outcomes in patients undergoing rehabilitation from ankle injury?\n2. How does semiconductor embedded socks effect injury symptoms and function throughout the course of treatment?\n\nResearchers will compare semiconductor embedded socks with typical compression socks to determine differences in healing.\n\nParticipants will be given the socks and be asked to wear them throughout the healing process and record symptoms and functional measures.",[29],[88,89,90,91],"ankle sprain","ligamentous sprain","avulsion fracture","distal fibula fracture","2026-04-27",{"date":94,"type":42},"2026-05-01",{"date":96,"type":42},"2025-04-10",{"date":98,"type":22},"2027-12-31",{"name":100,"class":49},"University of Colorado, Denver",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":108,"enrollmentInfo":109,"targetDuration":4,"studyType":23,"phases":111,"briefSummary":112,"conditions":113,"keywords":4,"overallStatus":118,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":4},"100628336","comparison-of-anesthetic-techniques-for-early-recovery-after-ankle-arthroscopy-100628336","NCT07460310","Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy","Comparison of Total Intravenous, Balanced, and Spinal Anesthesia for Early Recovery Following Ankle Arthroscopy: A Multicenter, Prospective, Randomized Controlled Trial.","Inclusion Criteria:\n\n* Full understanding of the study procedures and methods, with a signed written informed consent form.\n* Aged 18 to 65 years, of either sex.\n* Scheduled for elective unilateral minimally invasive ankle surgery.\n* American Society of Anesthesiologists (ASA) physical status classification I or II.\n* Body Mass Index (BMI) between 16 and 32 kg\u002Fm\\^2\n\nExclusion Criteria:\n\n* Known hypersensitivity or allergy to any study medications or existing contraindications to anesthesia.\n* Chronic obstructive pulmonary disease (COPD) or unstable asthma.\n* History of difficult airway management, poorly controlled gastroesophageal reflux disease (GERD), or a known risk of aspiration.\n* Anticipated surgical duration exceeding 3 hours.\n* History of chronic preoperative opioid use or dependence.\n* History of severe postoperative adverse reactions (e.g., severe postoperative nausea and vomiting).\n* Pregnancy or lactation.\n* History of seizure disorders or epilepsy.\n* Severe peripheral neuropathy.\n* Any other condition that, in the opinion of the investigator, would preclude safe participation in the study.","65 Years",{"count":110,"type":22},200,[25],"Ankle arthroscopy is increasingly performed as a day-case procedure, making rapid recovery and efficient discharge critical. Anesthetic technique substantially influences postoperative recovery, yet high-quality evidence comparing anesthetic strategies in ankle arthroscopy is limited.\n\nThis multicenter randomized trial compares total intravenous anesthesia with propofol plus peripheral nerve block (PNB), general anesthesia plus PNB, and spinal anesthesia, with PACU-I recovery time as the primary outcome. Secondary outcomes include postoperative pain, opioid consumption, hospital length of stay, adverse events, recovery quality, satisfaction, limb weakness, and intraoperative hemodynamics.",[29,114,115,116,117],"Ankle (Ligaments); Instability (Old Injury)","Pain Management","ERAS","Ankle Arthroscopy","NOT_YET_RECRUITING","2026-03-04",{"date":121,"type":42},"2026-03-10",{"date":123,"type":22},"2026-03-01",{"date":125,"type":22},"2026-12-30",{"name":127,"class":49},"Second Affiliated Hospital, School of Medicine, Zhejiang University",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":135,"enrollmentInfo":136,"targetDuration":4,"studyType":23,"phases":138,"briefSummary":139,"conditions":140,"keywords":141,"overallStatus":118,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":4},"100624103","the-efficacy-of-hyperbaric-oxygen-on-acute-ankle-sprain-100624103","NCT07405281","the Efficacy of Hyperbaric Oxygen on Acute Ankle Sprain","A Multicenter, Prospective Clinical Randomized Controlled Study of the Efficacy of Hyperbaric Oxygen on Acute Ankle Sprain","Inclusion Criteria:\n\n* Unilateral ankle sprain;\n* Swelling, bruising, and pain at the site of the sprain;\n* Injury occurring within 72 hours;\n* MRI examination clearly shows ligament damage.\n\nExclusion Criteria:\n\n* X-ray shows ankle fracture;\n* Ankle has skin lesions or skin diseases;\n* History of lower limb and pelvic surgery;\n* Obvious neurological or psychiatric disorders that may interfere with assessment;\n* Severe ligament injuries or joint instability requiring surgical treatment;\n* Previous ankle injuries, persistent pain or functional limitations;\n* Pneumothorax, severe emphysema, active bleeding, or other diseases with contraindications for hyperbaric oxygen therapy.","60 Years",{"count":137,"type":22},208,[25],"Investigators recruited 208 patients with acute ankle sprain who were from the Rehabilitation Department of the Second Affiliated Hospital of Zhejiang University, School of Medicine from January 2026 to November 2028. Perform the improvement in AOFAS scores and Baird-Jackson ankle scores study and Rehabilitation assessments followed up after 3 years.",[29],[142,143],"acute ankle sprain","hyperbaric oxygen","2026-02-11",{"date":146,"type":42},"2026-02-12",{"date":148,"type":22},"2026-03",{"date":150,"type":22},"2029-03",{"name":127,"class":49},{"id":153,"slug":154,"hasResults":11,"nctId":155,"briefTitle":156,"officialTitle":157,"acronym":4,"eligibilityCriteria":158,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":159,"enrollmentInfo":160,"targetDuration":4,"studyType":23,"phases":162,"briefSummary":163,"conditions":164,"keywords":165,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":50},"100607595","nmes-with-pnf-for-ankle-sprain-rehabilitation-100607595","NCT07190599","NMES With PNF for Ankle Sprain Rehabilitation","Effects of Neuromuscular Electrical Stimulation Combined With Proprioceptive Neuromuscular Facilitation in Adults With a History of Ankle Sprain","Inclusion Criteria:\n\n* Aged 18-30 years\n* Adults with a history of ankle sprain\n\nExclusion Criteria:\n\n* Participants with ankle fractures, dislocations, grade III ankle sprains, bony restrictions, swelling, neuropathy, or any other neuromuscular disorders are excluded.","30 Years",{"count":161,"type":22},60,[25],"Ankle sprains are one of the most common sports injuries. In some people, they can lead to chronic ankle problems that affect daily life and sports performance. In this study, we want to see if combining neuromuscular electrical stimulation (NMES) with proprioceptive neuromuscular facilitation (PNF) can help improve these problems. We plan to recruit 60 participants, with 30 in the experimental group and 30 in the control group. The experimental group will receive PNF stretching with NMES, while the control group will only do PNF stretching. Both groups will have training three times a week for four weeks (12 sessions in total). We will test participants before and after the program, looking at pain, balance, range of motion, proprioception, strength, joint mobility, and functional limitations. We expect that 12 sessions will help improve chronic ankle problems, and that NMES combined with PNF will be more effective than PNF alone.",[29],[166,167,168,169,170,171],"Ankle sprain","Balance","Proprioception","Strength","Pain","Range of motion","2025-11-14",{"date":174,"type":42},"2025-11-17",{"date":176,"type":42},"2025-10-01",{"date":178,"type":22},"2026-07-31",{"name":180,"class":49},"Fooyin University",{"id":182,"slug":183,"hasResults":11,"nctId":184,"briefTitle":185,"officialTitle":186,"acronym":4,"eligibilityCriteria":187,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":188,"targetDuration":4,"studyType":23,"phases":190,"briefSummary":191,"conditions":192,"keywords":193,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":198,"lastUpdatePostDateStruct":199,"startDateStruct":200,"completionDateStruct":202,"leadSponsor":204,"locationsCount":50},"100608339","surgical-management-of-lateral-ankle-instability-modified-brostrm-gould-versus-arthroscopic-allograft-reconstruction-of-the-anterior-talofibular-and-calcaneofibular-ligaments-100608339","NCT07200271","Surgical Management of Lateral Ankle Instability: Modified Broström-Gould Versus Arthroscopic Allograft Reconstruction of the Anterior Talofibular and Calcaneofibular Ligaments.","Surgical Management of Lateral Ankle Instability: Modified Broström-Gould Versus Arthroscopic Allograft Reconstruction of the Anterior Talofibular and Calcaneofibular Ligaments. A Randomized Stratified Clinical Trial.","Inclusion Criteria:\n\nMandatory criteria (all must be marked \"yes\" in a drop-down tab):\n\n* Age \\>18 years\n* Subjective sensation of instability\n* Pathological anterior drawer and varus tilt compared to the contralateral side\n* Magnetic resonance imaging showing lesion of the anterior talofibular ligament (ATFL)\n\nSpecific criteria (must meet at least one, but can meet several, multiple choice option):\n\n* BMI \\>30\n* High athletic demand (regularly participates in pivoting sports)\n* Ligamentous hyperlaxity (Beighton score \\>8)\n* First sprain more than 2 years ago\n* More than 5 sprains per year\n* Subfibular ossicle \\>1 cm\n* MRI with ATFL showing high T2 signal\n* MRI showing disruption\u002Fabsence of ATFL\n\nExclusion Criteria:\n\n* History of previous ankle surgery\n* Tibiotalar osteoarthritis or presence of chondral lesions on magnetic resonance imaging\n* Active infections\n* Contraindications for surgery\n* Pregnancy\n* Lactation\n* Known allergy to bovine collagen\n* Autoimmune connective tissue disease\n* Active oncological process",{"count":189,"type":22},36,[25],"Primary Objective:\n\nTo clarify whether arthroscopic reconstruction with allograft provides tangible benefits over the modified open Broström-Gould technique, or if both are equivalent in efficacy and safety. The clinical AOFAS scale will be used for assessment.\n\nSecondary Objectives:\n\nTo determine if there are differences in health outcomes and patient-perceived pain using the specific SP-36 scale and verbal numeric rating scale (VNRS). Additionally, to assess differences in postoperative complication rates and time to return to daily life activities between the two surgical techniques.\n\nStudy Design:\n\nProspective, randomized, controlled clinical trial with two parallel groups stratified by age and functional demand.\n\nCondition or Disorder Being Studied:\n\nChronic lateral ankle instability.\n\nStudy Population and Sample Size:\n\nThe target population includes subjects diagnosed with chronic lateral ankle instability. The study population consists of patients diagnosed in the Orthopedics consultations at Hospital Infanta Elena who meet the inclusion and exclusion criteria. Based on sample size calculations, a total of 36 patients will be recruited. However, due to the prospective nature and stratification by epidemiological and functional variables, the sample size may be increased to ensure comparable groups in each stratum.\n\nStudy Timeline and Estimated Completion Date:\n\nThe study is expected to begin in the third quarter of 2025. Recruitment is estimated to last 24 months, with a follow-up period of 12 months, for a total duration of 3 years, ending in the third quarter of 2028.",[29],[194,195,196,197],"ALLOGRAFT","INSTABILITY","ANKLE","LIGAMENT","2025-09-26",{"date":176,"type":42},{"date":201,"type":42},"2025-09-01",{"date":203,"type":22},"2028-09-01",{"name":205,"class":49},"Universidad Francisco de Vitoria",{"id":207,"slug":208,"hasResults":11,"nctId":209,"briefTitle":210,"officialTitle":210,"acronym":4,"eligibilityCriteria":211,"healthyVolunteers":212,"sex":17,"minAge":18,"maxAge":108,"enrollmentInfo":213,"targetDuration":4,"studyType":23,"phases":215,"briefSummary":216,"conditions":217,"keywords":4,"overallStatus":118,"whyStopped":4,"lastUpdateSubmitDate":219,"lastUpdatePostDateStruct":220,"startDateStruct":222,"completionDateStruct":223,"leadSponsor":225,"locationsCount":4},"100608133","validity-and-reliability-of-calf-raise-tests-in-patients-with-achilles-tendon-rupture-and-lateral-ankle-sprain-100608133","NCT07197593","Validity and Reliability of Calf Raise Tests in Patients With Achilles Tendon Rupture and Lateral Ankle Sprain","General Inclusion Criteria:\n\n* Signed informed consent\n* Aged 18-65 years\n* German or English speaking\n\nInclusion Criteria:\n\nLAS individuals: Unilateral LAS 4-16 weeks post-injury diagnosed by a physician as LAS, supination trauma, ankle distortion or ligamentous ankle injury.\n\nATR individuals: Unilateral ATR 6- 24 months post-injury\u002Fsurgery (surgical or conservative treatment).\n\nHealthy controls: Matched to Patients by Group Level: Physical Activity, Age and Gender.\n\nExclusion Criteria:\n\nLAS individuals: Medial Ligament injuries (Grade II or III) ATR individuals: Previous ATR\n\nGeneral Exclusion Criteria:\n\n* Chronic Ankle Instability (defined by symptoms such as giving way, perceived instability and at least one LAS within the last 6 months)\n* Previous ATR\n* Other lower limb injury and\u002For surgery in the last year (e.g. fractures, ligament reconstructions or other conditions resulting in ≥ 6 months of sports inactivity)\n* Impaired motor function of the lower limb due to neurovascular or neurological diseases\n* Vestibular or visual disturbances\n* Or any other pathoanatomic abnormality that would affect motor performance (e.g. foot arthrodesis, toe amputation\u002Fmissing toes or other conditions such as joint deformities, severe chronic pain).",true,{"count":214,"type":22},70,[25],"This study aims to evaluate the validity and reliability of clinically used Calf Raise Test parameters (collected with the \"the Calf Raise App\") between patients with Lateral Ankle Sprain or Achilles Tendon Repair and healthy controls.",[218,29],"Achilles Tendon","2025-09-22",{"date":221,"type":42},"2025-09-29",{"date":176,"type":22},{"date":224,"type":22},"2026-05-31",{"name":226,"class":49},"Schulthess Klinik",{"id":228,"slug":229,"hasResults":11,"nctId":230,"briefTitle":231,"officialTitle":231,"acronym":4,"eligibilityCriteria":232,"healthyVolunteers":212,"sex":17,"minAge":18,"maxAge":233,"enrollmentInfo":234,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":236,"conditions":237,"keywords":239,"overallStatus":118,"whyStopped":4,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":245,"startDateStruct":247,"completionDateStruct":248,"leadSponsor":250,"locationsCount":50},"100605544","validation-of-a-portable-ankle-arthrometer-100605544","NCT07163897","Validation of a Portable Ankle Arthrometer","Aim 1:\n\nInclusion Criteria:\n\n* Young adults between the ages of 18 and 40.\n* Willingness and ability to comply with scheduled visits and study procedures.\n* Fit one of the three groups: 1. Healthy - no history of ankle sprain, 2. Copers - one previous ankle sprain with no residual problems, 3. Chronic Ankle Instability.\n* Ability to sign consent.\n\nAim 2:\n\nInclusion Criteria:\n\n* Young adults between the ages of 18 and 40.\n* Willingness and ability to comply with scheduled visits and study procedures.\n* Acute ankle sprain within the last 48-96 hours.\n* Ability to sign consent.\n\nAim 1:\n\nExclusion Criteria:\n\n* Previous history of ankle fracture.\n* Diagnosis of Ehlers-Danlos Syndrome\n\nAim 2:\n\nExclusion Criteria:\n\n* Previous history of ankle fracture.\n* Diagnosis of Ehlers-Danlos Syndrome.","40 Years",{"count":235,"type":22},62,"The purpose of this study is to assess the validity and reliability of a prototype portable ankle arthrometer in various populations. There are two aims to this study. Aim 1 will look to determine the reliability and validity of a prototype portable ankle arthrometer on young adults with no history of ankle sprain, copers, and young adults with chronic ankle instability. It is hypothesized that the prototype portable ankle arthrometer will be a valid and reliable tool to assess joint laxity across the three different populations. Aim 2 will look to determine the validity of a prototype portable ankle arthrometer in young adults with an acute ankle sprain across multiple timepoints in their first month post injury. It is hypothesized that the prototype portable ankle arthrometer will be a valid tool to assess joint laxity at three different timepoints for the same individual.",[28,29,238],"Healthy",[240,241,242,243],"Arthrometer","Ankle","Validity","Reliability","2025-09-04",{"date":246,"type":42},"2025-09-09",{"date":176,"type":22},{"date":249,"type":22},"2026-10-01",{"name":251,"class":49},"University of Virginia",{"id":253,"slug":254,"hasResults":11,"nctId":255,"briefTitle":256,"officialTitle":257,"acronym":258,"eligibilityCriteria":259,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":260,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":262,"conditions":263,"keywords":264,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":269,"lastUpdatePostDateStruct":270,"startDateStruct":272,"completionDateStruct":274,"leadSponsor":276,"locationsCount":50},"100369842","computed-tomography-with-stress-maneuvers-for-evaluation-of-distal-tibiofibular-syndesmosis-instability-ctmets-100369842","NCT04095598","Computed Tomography with Stress Maneuvers for Evaluation of Distal Tibiofibular Syndesmosis Instability (CTMETS)","Comparative Computed Tomography with Stress Maneuvers for Evaluation of Distal Tibiofibular Syndesmosis Instability in Adults After Acute Ankle Sprain: a Test Accuracy Study","CTMETS","Inclusion criteria:\n\n* Adults older than 18 years;\n* One episode of an ankle sprain;\n* Sprain episode occurred up to 3 weeks prior;\n* Positive orthopedic evaluation for suspected syndesmotic injury.\n\nExclusion criteria\n\n* Bilateral ankle sprain;\n* Previous ankle surgery;\n* Ankle fractures and dislocations (except avulsion fractures in ligamentous insertions or fracture of the posterior malleolus related to syndesmotic injury);\n* Congenital or acquired ankle deformities;\n* Infection, inflammatory, or neuropathic ankle arthropathies.",{"count":261,"type":22},133,"The main aim of this study was to investigate which strategy can diagnose more accurately syndesmotic instability among an existing index test (ankle CT in neutral position) and two new add-on index tests (ankle CT in a stress position with extended-knees and ankle CT in a stress position with flexed-knees). This study hypothesized that the two add-on ankle CT with stress maneuvers (CTSM) have a more accurate capability of diagnosing syndesmotic instability than ankle CT in a neutral position (CTNP) alone. The secondary objective is to investigate the participants' disability outcomes by applying the Foot and Ankle Ability Measure questionnaire.",[29],[265,266,267,268],"High ankle sprain","Syndesmotic instability","Computed Tomography","Stress maneuver","2024-10-15",{"date":271,"type":42},"2024-10-17",{"date":273,"type":42},"2018-09-01",{"date":275,"type":22},"2027-12",{"name":277,"class":49},"Hospital Israelita Albert Einstein"]