[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ankyloglossia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ankyloglossia":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100635837","healing-efficacy-of-diode-laser-in-lingual-frenectomy-100635837",false,"NCT07557875","Healing Efficacy of Diode Laser in Lingual Frenectomy","Evaluation of the Healing Efficacy of Diode Laser in Lingual Frenectomy","Inclusion Criteria:\n\n* Patients aged between 3 and 6 years.\n* Diagnosed with grade 3 or grade 4 ankyloglossia according to Kotlow's classification (1999).\n* Parents or legal guardians provide informed consent for the child to participate in the study.\n* Patients and guardians agree to follow the follow-up schedule (24 hours, 3 days, 1 week, and 1 month post-surgery).\n\nExclusion Criteria:\n\n* History of allergy to local anesthetics (e.g., Lidocaine, Adrenaline).\n* Patients with systemic diseases or high-risk surgical factors (e.g., cardiovascular disease, bleeding disorders, hemophilia, epilepsy, or uncontrolled asthma).\n* Uncooperative patients who are unable to undergo the procedure under local anesthesia or fail to follow post-operative instructions.\n* Patients who withdraw from the study before completion.","ALL","3 Years","6 Years",{"count":20,"type":21},53,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to compare the wound healing efficacy and postoperative experiences between the 940 nm diode laser technique and the traditional electrosurgery method for treating ankyloglossia (tongue-tie) in children aged 3 to 6 years.\n\nParticipants are randomly assigned to one of two groups: Experimental Group - Patients undergo lingual frenectomy using a 940 nm diode laser and Active Comparator Group - Patients undergo the procedure using conventional high-frequency electrosurgery.\n\nThe study evaluates several key outcomes at multiple intervals (24 hours, 3 days, 1 week, and 1 month post-surgery), including: (1) Wound Healing: Measured by the Early Wound Healing Score (EHS); (2) Pain Levels: Assessed using the Wong-Baker FACES Pain Rating Scale; (3) Bleeding Control: Evaluation of intraoperative bleeding; (4) Tongue Mobility: Measurement of free tongue length according to Kotlow's classification.\n\nThe goal is to determine if the diode laser provides superior healing, less pain, and better bleeding control compared to electrosurgery.",[27,28],"Ankyloglossia","Tongue-tie",[27,28,30,31,32,33,34,35,36,37],"Lingual frenectomy","Diode laser","Electrosurgery","Wound healing","Postoperative pain","Early Wound Healing Score (EHS)","Wong-Baker FACES Pain Rating Scale","Kotlow's classification","RECRUITING","2026-04-22",{"date":41,"type":42},"2026-04-30","ACTUAL",{"date":44,"type":42},"2024-10-01",{"date":46,"type":21},"2026-10-01",{"name":48,"class":49},"University of Medicine and Pharmacy at Ho Chi Minh City","OTHER",{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":80},"100579888","post-procedural-manual-manipulation-for-infant-ankyloglossia-100579888","NCT06830148","Post-Procedural Manual Manipulation for Infant Ankyloglossia","Effectiveness of Post-Procedural Manual Manipulation for Infant Ankyloglossia in Enhancing Breastfeeding and Reducing Revision Rates: A Prospective Randomized Trial","Inclusion Criteria:\n\n* infants less than 90 days old with ankyloglossia who undergo outpatient frenotomy using cold-steel scissors and will be exclusively or partially breastfed.\n\nExclusion Criteria:\n\n* infants older than 90 days, those who will be exclusively bottle fed, infants who undergo concomitant lip tie release, those who undergo laser frenotomy, and infants who have previously undergone a frenotomy.\n* infants with a gestational age of less than 36 weeks, those in the NICU or post-partum unit, infants who didn't receive the vitamin K injection, and those with congenital anomalies or medical conditions affecting breastfeeding","90 Days",{"count":59,"type":21},110,[24],"The goal of this randomized control trial is to determine the impact of post-frenotomy manual manipulation on revision rates and breastfeeding outcomes. We hypothesize that post-frenotomy manipulation will reduce the rate of sublingual frenulum regrowth, and subsequently frenotomy revision rates, thereby improving breastfeeding performance.\n\nInfants with ankyloglossia undergoing frenotomy will be randomized into two groups: the intervention group (post-frenotomy manipulation) and the control group (no intervention). Parents in the intervention group will be instructed to perform tongue stretching and suck \"re-training\" exercises four times daily for 2-3 weeks, beginning 24 hours post-procedure. To monitor adherence and assess any complications, investigators will conduct a follow-up phone call one week after the procedure. Parents in the control group will not be instructed to perform any post-procedural manipulation. All participants will have a mandatory in-person follow-up 2-3 weeks postoperatively, during which breastfeeding outcomes and the need for frenotomy revision will be evaluated.",[27,63],"Breastfeeding Support",[65,66,67,68,69,70],"tongue tie","breastfeeding","exercises","infant","pediatric otolaryngology","frenotomy","2025-02-11",{"date":73,"type":42},"2025-02-17",{"date":75,"type":42},"2024-10-15",{"date":77,"type":21},"2025-11",{"name":79,"class":49},"Georgetown University",1]