[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anorexia-nervosa-in-remission\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anorexia-nervosa-in-remission":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100516150","therapeutic-ketogenic-diet-in-anorexia-nervosa-100516150",false,"NCT06000774","Therapeutic Ketogenic Diet in Anorexia Nervosa","Ketogenic Diet in Eating Disorders to Target Metabolism and Normalize Persistent Eating Disorder Psychopathology","Weight-Recovered AN Inclusion Criteria:\n\n1. Provision of signed and dated informed consent form\n2. Stated willingness to comply with all study procedures and availability for the duration of the study\n3. Persons, aged 18 to 45 years\n4. History of anorexia nervosa according to DSM-5 criteria\n5. Weight recovered at the time of study inclusion (body mass index \\> 17.5 kg\u002Fm2)\n6. Greater or equal to 2 standard deviations scores of eating disorder-relevant behaviors on the Eating Disorder Inventory-3 and Eating Disorder Examination Questionnaire\n7. The following types of psychiatric medications are allowed: antidepressant, anxiolytic, atypical antipsychotic, mood stabilizers\n8. English is primary spoken language\n\nWeight-Recovered AN Exclusion Criteria:\n\n1. Pregnancy or lactation\n2. Electrolyte, blood count, kidney function or liver function abnormalities\n3. Psychosis\n4. Neurocognitive disorders including dementias or traumatic brain injury that is symptomatic\n5. Current alcohol use disorder (AUD) or substance use disorder (SUD) according to DSM-5 criteria\n6. Uncontrolled hypertension\n7. Hepatic impairment (Class-Pugh b or c)\n8. Diabetes mellitus\n9. Family history of porphyria\n10. History of recent heart attack, vascular disease, or any other current acute medical conditions as determined by the principal investigator\n11. Inability or unwillingness to adhere to the TKD diet for the duration of the study\n12. Blind or illiterate individuals\n\nUnderweight AN Sub-Study Inclusion Criteria:\n\n1. Provision of signed and dated informed consent form\n2. Stated willingness to comply with all study procedures and availability for the duration of the study\n3. Persons, aged 18 to 45 years\n4. Anorexia nervosa according to DSM-5 criteria\n5. Current Body Mass Index (BMI) at the time of study inclusion of 16.0 to 17.49\n6. An elevated EDE-Q global score of 2.09 or greater\n7. The following types of psychiatric medications are allowed: antidepressant, anxiolytic, atypical antipsychotic, mood stabilizers\n8. English is primary spoken language\n\nUnderweight AN Sub-Study Exclusion Criteria:\n\n1. Pregnancy or lactation\n2. Electrolyte, blood count, kidney function or liver function abnormalities\n3. Psychosis\n4. Neurocognitive disorders including dementias or traumatic brain injury that is symptomatic\n5. Current alcohol use disorder (AUD) or substance use disorder (SUD) according to DSM-5 criteria\n6. Uncontrolled hypertension\n7. Hepatic impairment (Class-Pugh b or c)\n8. Diabetes mellitus\n9. Family history of porphyria\n10. History of recent heart attack, vascular disease, or any other current acute medical conditions as determined by the principal investigator\n11. Inability or unwillingness to adhere to the TKD diet for the duration of the study\n12. Blind or illiterate individuals\n\nBulimia Nervosa Pilot Inclusion Criteria:\n\n1. Provision of signed and dated informed consent form\n2. Stated willingness to comply with all study procedures and availability for the duration of the study\n3. Persons, aged 18 to 45 years\n4. History of bulimia nervosa according to DSM-5 criteria\n5. An elevated EDE-Q global score of 2.09 or greater\n6. The following types of psychiatric medications are allowed: antidepressant, anxiolytic, atypical antipsychotic, mood stabilizers\n7. English is primary spoken language\n\nBulimia Nervosa Pilot Exclusion Criteria:\n\n1. Pregnancy or lactation\n2. Electrolyte, blood count, kidney function or liver function abnormalities\n3. Psychosis\n4. Neurocognitive disorders including dementias or traumatic brain injury that is symptomatic\n5. Current alcohol use disorder (AUD) or substance use disorder (SUD) according to DSM-5 criteria\n6. Uncontrolled hypertension\n7. Hepatic impairment (Class-Pugh b or c)\n8. Diabetes mellitus\n9. Family history of porphyria\n10. History of recent heart attack, vascular disease, or any other current acute medical conditions as determined by the principal investigator\n11. Inability or unwillingness to adhere to the TKD diet for the duration of the study\n12. Blind or illiterate individuals","ALL","18 Years","45 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will investigate the effects of therapeutic ketogenic diet (TKD) on eating behavior including drive to restrict, body dissatisfaction, mood and anxiety in individuals with anorexia nervosa who have been weight normalized (body mass index of 17.5 or greater) but continue to struggle with eating disorder behaviors including a high drive for thinness and body dissatisfaction.\n\nThe Underweight Anorexia Nervosa (AN) Sub-Study will investigate the effects of TKD on eating behavior including drive to restrict, body dissatisfaction, mood and anxiety in individuals with anorexia nervosa who are currently underweight (body mass index between 16.0 and 17.49) and continue to struggle with eating disorder behaviors including a high drive for thinness and body dissatisfaction.\n\nThe Bulimia Nervosa Pilot will will investigate the effects of TKD on eating behavior including drive to binge and purge, body dissatisfaction, mood and anxiety in individuals with bulimia nervosa.",[27,28,29],"Anorexia Nervosa in Remission","Bulimia Nervosa","Anorexia Nervosa","RECRUITING","2025-08-28",{"date":33,"type":34},"2025-09-05","ACTUAL",{"date":36,"type":34},"2023-10-03",{"date":38,"type":21},"2027-06-30",{"name":40,"class":41},"University of California, San Diego","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":17,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":42},"100519966","radically-open-dialectical-behaviour-therapy-in-patients-with-anorexia-nervosa-100519966","NCT06050421","Radically Open Dialectical Behaviour Therapy in Patients With Anorexia Nervosa","Evaluating the Efficacy of Radically Open Dialectical Behaviour Therapy (RO-DBT) in Patients With Anorexia Nervosa: a Randomized Controlled Clinical Trial","RODBT-AN","Inclusion Criteria:\n\n* female patients\n* aged between 18 to 65 years old,\n* having a diagnosis of AN (DSM 5 criteria),\n* having had weigh restoration treatment (normal BMI considered \\>19 kg\u002Fm2)\n* having an overcontrol personality style assessed with the styles of coping Word-Pair Checklist scale (ASC-WP)\n\nExclusion Criteria:\n\n* diagnosis of severe mental illness (schizophrenia or other psychosis, bipolar disorder, major depressive disorder, substance use disorder)\n* diagnosis of borderline personality disorder (BPD) or positive result in McLean Screening Instrument for BPD\n* mental retardation\n* being under standardized psychotherapy at the baseline\n* being illiterate or not able to understand Spanish language,\n* being left-handed\n* being pregnant for MRI requirements.",true,"FEMALE","65 Years",{"count":55,"type":21},96,[24],"Randomized controlled clinical trial to evaluate the efficacy of \"Radically Open Dialectical Behaviour Therapy\" in patients with eating disorders: a proof-of-concept study.",[29,27,59],"Anorexia Nervosa Restricting Type",[61],"anorexia nervosa, RODBT","2023-09-15",{"date":64,"type":34},"2023-09-22",{"date":66,"type":34},"2023-06-22",{"date":68,"type":21},"2026-06-30",{"name":70,"class":41},"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau"]