[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"antenatal-care\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:antenatal-care":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,64,98,136],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":36,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":63},"100628220","healthy-expectancy-through-routine-antenatal-sti-screening-100628220",false,"NCT07458802","Healthy Expectancy Through Routine Antenatal STI Screening","Screening and Treatment for Chlamydia Trachomatis Infection to Prevent Preterm Birth","HERA","Inclusion Criteria:\n\n1. Asymptomatic for cervicovaginitis at first ANC (i.e., not syndromically treated for an STI by clinic midwives at first ANC)\n2. Age ≥ 15 years\n3. Currently pregnant\n4. ≤20 weeks gestation (based on gestational age in obstetric record or last menstrual period if gestational age missing from record)\n5. Attending first ANC visit\n6. Residence in Gaborone, Bostwana or surrounding villages through the time of delivery\n7. Mentally competent to understand study procedures or give informed consent",true,"FEMALE","15 Years",{"count":21,"type":22},2000,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study will evaluate whether routine screening and treatment for two common sexually transmitted infections, chlamydia and gonorrhoea, during pregnancy can reduce preterm birth and other poor birth outcomes in Botswana, and whether this approach is affordable and cost-effective for the health system.\n\nAbout 2,000 pregnant women attending their first antenatal care visit at up to 10 government clinics in Botswana will be invited to join the study. All women will first receive the usual antenatal care services provided in Botswana, including routine health checks and HIV and syphilis testing. Women who enroll in the study will be randomly assigned to one of two groups:\n\n1. Standard of care group: Women receive routine antenatal care only.\n2. Intervention group: In addition to routine antenatal care, women are screened for chlamydia and gonorrhoea using self-collected vaginal swabs at their first antenatal care visit and again in the third trimester.\n\nThe main outcome of the study is whether screening and treating chlamydia and gonorrhoeae reduces preterm birth (before 37 weeks). Other outcomes include low birth weight, very preterm birth, and maternal health conditions.",[28,29,30,31,32,33,34,35],"Antenatal Health","Antenatal Care","STI","Chlamydia Trachomatis Infection in Pregnancy","Chlamydia","Chlamydia Trachomatis","Chlamydia Trachomatis Infection","Preterm Birth",[37,38,39,40,41,42,43,30,44,45,46,47,48,49,50],"antenatal health","antenatal screening","chlamydia","chlamydia trachomatis","chlamydia screening","chlamydia treatment","pregnancy screening","STI screening","STI in pregnancy","preterm delivery","Botswana","CT infection","chlamydia in pregnancy","birth outcomes","RECRUITING","2026-06-30",{"date":54,"type":55},"2026-07-02","ACTUAL",{"date":57,"type":55},"2026-05-25",{"date":59,"type":22},"2030-07-01",{"name":61,"class":62},"Adriane Wynn","OTHER",1,{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":17,"sex":18,"minAge":72,"maxAge":4,"enrollmentInfo":73,"targetDuration":4,"studyType":75,"phases":4,"briefSummary":76,"conditions":77,"keywords":82,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":63},"100645180","ai-blind-sweep-ultrasound-for-antenatal-screening-by-non-specialist-health-workers-in-rural-dr-congo-100645180","NCT07677670","AI Blind-Sweep Ultrasound for Antenatal Screening by Non-Specialist Health Workers in Rural DR Congo","Diagnostic Accuracy and Implementation Feasibility of AI-Assisted Blind Ultrasound Sweep (SPAQ E-con AI) for Antenatal Screening by Non-Specialist Health Workers in Rural Democratic Republic of the Congo","FS2","Inclusion Criteria:\n\n* Pregnant women\n* Identified at a participating facility routine ANC visit or RECO village outreach within the Kenge health zone catchment\n* Informed consent obtained (16-17 years with parent\u002Fguardian consent)\n\nExclusion Criteria:\n\n* Emergency presentation\n* Multiple pregnancy\n* Duplicate re-registration of an already-enrolled woman\n* Lacking capacity to consent\n* Planned relocation outside Kwango province during the study period\n* Refusal of consent","16 Years",{"count":74,"type":22},3000,"OBSERVATIONAL","FS2 evaluates the diagnostic accuracy and implementation feasibility of an AI-assisted blind-sweep obstetric ultrasound (SPAQ E-con AI), operated by trained non-specialist health workers, for antenatal screening in rural Democratic Republic of the Congo. Primary outcomes are gestational age mean absolute error (Trimester 2 and Trimester 3) with 95% confidence intervals and AI confidence calibration. The reference standard is manual measurement by a reference reader (early ultrasound first; manual BPD if unavailable; last menstrual period is not used). Target enrollment is approximately 1,430 (IRB-approved ceiling 3,000), with early termination permitted upon achievement of pre-specified analysis-plan thresholds. The study is a multi-center prospective Hybrid Type 1 Effectiveness-Implementation design and includes a pre-specified adaptive model-update (Batch 2 cut) plan following FDA PCCP and STARD-AI guidance.",[29,78,79,80,81],"Maternal Health","Gestational Age","Placenta Praevia","Diagnostic Imaging",[83,84,85,86,87],"blind sweep ultrasound","artificial intelligence","point-of-care ultrasound","task-shifting","DRC","2026-06-24",{"date":90,"type":55},"2026-07-01",{"date":92,"type":55},"2026-06-19",{"date":94,"type":22},"2027-06-13",{"name":96,"class":97},"SOIK Corporation Sarl","INDUSTRY",{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":4,"eligibilityCriteria":104,"healthyVolunteers":17,"sex":105,"minAge":106,"maxAge":4,"enrollmentInfo":107,"targetDuration":4,"studyType":75,"phases":4,"briefSummary":109,"conditions":110,"keywords":118,"overallStatus":126,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":4},"100601744","addressing-pregnant-womens-first-trimester-worries-and-information-needs-with-mhealth-solutions-100601744","NCT07114471","Addressing Pregnant Women's First Trimester Worries and Information Needs With mHealth Solutions","Exploring the Anxieties and Health Information Needs of Women in the First Trimester to Inform mHealth Solutions for Antenatal Care","Pregnant women\n\nInclusion criteria\n\n* To ensure that participants have the first trimester of pregnancy fresh in their minds the sample will include women that are currently pregnant or have had a child within the last 2 years\n* Living in the UK\n* Over the age of 18\n* Able to give informed consent Exclusion criteria\n* Evidence of\u002Fdiagnosis of cognitive impairment\n\nHealthcare professionals\n\nInclusion criteria\n\n\\- Belonging to one of the following professional groups i.e. healthcare professionals involved in the care of pregnant women\n\n* Doctor in obstetrics and gynaecology\n* Midwives\n* Nurses (within the field of obstetrics and gynaecology),\n* Sonographers that scan pregnant women\n* General practitioners\n* Psychologists (that work with pregnant women)\n* Physiotherapists (that work with pregnant women)\n* Living in the UK\n* Over the age of 18\n* Able to give informed consent Exclusion criteria\n* Evidence of\u002Fdiagnosis of cognitive impairment\n\nDigital Health Experts\n\nInclusion criteria\n\n* Professionals with at least 3 year's experience in digital health, health informatics or mobile health application development\n* Based in the United Kingdom Exclusion criteria\n* Evidence of\u002Fdiagnosis of cognitive impairment","ALL","18 Years",{"count":108,"type":22},1450,"The first 12 weeks of pregnancy, known as the first trimester, can be one of the most worrying times for women. (Where this lay summary refers to women, it should be taken to include people who do not identify as women but who have the capacity to become pregnant). Many experience nausea, bleeding, or anxiety about whether the pregnancy is progressing normally. Despite this, most women do not see a midwife or doctor until around 10 weeks into the pregnancy. This leaves a gap where they may have important questions but little professional support. As a result, many turn to mobile phone applications or the internet to find answers - but the quality of information online is mixed, and it can be confusing or even unsafe.\n\nThis research aims to understand what support women really need in early pregnancy, what concerns they have, and whether a mobile health application (mHealth app) could help fill this gap in current pregnancy care in a safe and personalised way. The study will also ask healthcare professionals and digital health experts what such an application should include, and how it can be made accessible, and easy to understand for all women - including those with different levels of health knowledge and digital skills.\n\nTo carry out the research, we will use a combination of online surveys and interviews. Women who are currently pregnant or have had a baby in the last two years will be invited to take part, along with healthcare professionals such as midwives and doctors, and experts in digital health. The survey will ask about their experiences in early pregnancy, how they have used digital tools or apps, and whether they felt their questions were answered before their first NHS appointment. The interview stage will allow participants to talk in more depth about what support they wanted and what would have helped them most. All participants will receive information about support services because we realise that discussing unmet information needs or worries in early pregnancy may be upsetting for some women.\n\nThe views collected will inform the design of a new mobile application to support women during early pregnancy. The application will use artificial intelligence (AI) to personalise information based on each woman's needs and background, and to explain things clearly and simply. The content and design of the application will be reviewed by doctors and digital health specialists to make sure it is safe, accurate, and easy to use.\n\nPublic and patient involvement is central to this project. A diverse group of women and representatives from grassroots organisations will be invited to shape the questions we ask, review the design of the application, and help us make it inclusive for people from different backgrounds.\n\nThis research will help us create a practical, trustworthy, and inclusive tool to support women during one of the most vulnerable times in pregnancy when women don't usually see a doctor. If successful, it could be used widely across the NHS to help reduce anxiety, improve understanding, and ensure women get the right support earlier in their pregnancy with the long-term aim of improving outcomes for women, babies, and families across the UK.",[111,112,113,114,115,116,29,117],"Pregnancy Trimester, First","Anxiety","Worries","Health Knowledge, Attitudes, Practice","mHealth Application","Mobile Application","Patient Education as Topic",[119,120,121,122,123,124,125],"Observational Study","Surveys and Questionnaires","Interview","Digital Health","Health Literacy","Pregnant People","User Centered Design","NOT_YET_RECRUITING","2025-08-11",{"date":129,"type":55},"2025-08-14",{"date":131,"type":22},"2025-09",{"date":133,"type":22},"2027-10",{"name":135,"class":62},"Bournemouth University",{"id":137,"slug":138,"hasResults":11,"nctId":139,"briefTitle":140,"officialTitle":141,"acronym":4,"eligibilityCriteria":142,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":23,"phases":145,"briefSummary":146,"conditions":147,"keywords":150,"overallStatus":126,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":159,"leadSponsor":161,"locationsCount":4},"100599953","a-culturally-adapted-digital-intervention-to-promote-maternal-care-utilization-using-multifaceted-approaches-100599953","NCT07091188","A Culturally Adapted Digital Intervention to Promote Maternal Care Utilization Using Multifaceted Approaches","A Culturally Adapted Digital Intervention to Promote Maternal Care Utilization Using Multifaceted Approaches (CALCIUM) Among an Ethnic Minority Community in China","Inclusion Criteria:\n\n* Pregnant women\n\nExclusion Criteria:\n\n* Not pregnant women",{"count":144,"type":22},1920,[25],"Maternal healthcare utilization is crucial for reducing maternal mortality, yet remains low in many underserved regions. The CALCIUM intervention, a culturally tailored, digital platform-integrated intervention, was developed to promote antenatal care (ANC) and institutional deliveries in Liangshan Yi Autonomous Prefecture, an ethnic minority community in China. The CALCIUM intervention was developed to address barriers including limited healthcare awareness, traditional norms and low-quality services. This intervention will evaluate the effectiveness, and cost-effectiveness of improving maternal healthcare utilization and pregnancy outcomes in an ethnic minority community.",[29,148,149],"Pregnancy Complications","Pregnancy Outcomes",[151,152,153,154],"antenatal care","ethnic minority","digital health","health education","2025-07-25",{"date":157,"type":55},"2025-07-29",{"date":131,"type":22},{"date":160,"type":22},"2027-06",{"name":162,"class":62},"Jiayao Xu"]