[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"antenatal-health\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:antenatal-health":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,64,91],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":36,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":63},"100628220","healthy-expectancy-through-routine-antenatal-sti-screening-100628220",false,"NCT07458802","Healthy Expectancy Through Routine Antenatal STI Screening","Screening and Treatment for Chlamydia Trachomatis Infection to Prevent Preterm Birth","HERA","Inclusion Criteria:\n\n1. Asymptomatic for cervicovaginitis at first ANC (i.e., not syndromically treated for an STI by clinic midwives at first ANC)\n2. Age ≥ 15 years\n3. Currently pregnant\n4. ≤20 weeks gestation (based on gestational age in obstetric record or last menstrual period if gestational age missing from record)\n5. Attending first ANC visit\n6. Residence in Gaborone, Bostwana or surrounding villages through the time of delivery\n7. Mentally competent to understand study procedures or give informed consent",true,"FEMALE","15 Years",{"count":21,"type":22},2000,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study will evaluate whether routine screening and treatment for two common sexually transmitted infections, chlamydia and gonorrhoea, during pregnancy can reduce preterm birth and other poor birth outcomes in Botswana, and whether this approach is affordable and cost-effective for the health system.\n\nAbout 2,000 pregnant women attending their first antenatal care visit at up to 10 government clinics in Botswana will be invited to join the study. All women will first receive the usual antenatal care services provided in Botswana, including routine health checks and HIV and syphilis testing. Women who enroll in the study will be randomly assigned to one of two groups:\n\n1. Standard of care group: Women receive routine antenatal care only.\n2. Intervention group: In addition to routine antenatal care, women are screened for chlamydia and gonorrhoea using self-collected vaginal swabs at their first antenatal care visit and again in the third trimester.\n\nThe main outcome of the study is whether screening and treating chlamydia and gonorrhoeae reduces preterm birth (before 37 weeks). Other outcomes include low birth weight, very preterm birth, and maternal health conditions.",[28,29,30,31,32,33,34,35],"Antenatal Health","Antenatal Care","STI","Chlamydia Trachomatis Infection in Pregnancy","Chlamydia","Chlamydia Trachomatis","Chlamydia Trachomatis Infection","Preterm Birth",[37,38,39,40,41,42,43,30,44,45,46,47,48,49,50],"antenatal health","antenatal screening","chlamydia","chlamydia trachomatis","chlamydia screening","chlamydia treatment","pregnancy screening","STI screening","STI in pregnancy","preterm delivery","Botswana","CT infection","chlamydia in pregnancy","birth outcomes","RECRUITING","2026-06-30",{"date":54,"type":55},"2026-07-02","ACTUAL",{"date":57,"type":55},"2026-05-25",{"date":59,"type":22},"2030-07-01",{"name":61,"class":62},"Adriane Wynn","OTHER",1,{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":11,"sex":18,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":4,"studyType":23,"phases":75,"briefSummary":76,"conditions":77,"keywords":4,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":63},"100588482","partnering-with-antenatal-navigators-to-transform-health-in-pregnancy-100588482","NCT06941974","Partnering With Antenatal Navigators to Transform Health in Pregnancy","PATH","Inclusion Criteria:\n\n* Singleton gestation \\\u003C20 weeks of gestation\n* Nulliparous: no prior pregnancies ≥20 weeks excluding terminations\n* Low income (public insurance or residence in a neighborhood in which \\>10% of household incomes are \\\u003C125% of federal poverty line\n* Ability to speak and read English or Spanish\n* Established patient at one of practices associated with Northwestern Medical Group\n* Age 16 years or older\n\nExclusion:\n\n* Intent to transfer care to an outside institution\n* Prior enrollment in PATH\n* Concurrent enrollment in a study with competing aims\u002Fintervention","16 Years","50 Years",{"count":74,"type":22},600,[25],"The Partnering with Antenatal Navigators to Transform Health in Pregnancy (PATH) study aims to evaluate whether an antenatal patient navigation program improves maternal health, neonatal health, pregnant women's experiences, and health care utilization outcomes among low-income pregnant women and their neonates. Patient navigation is an individualized, barrier-focused, longitudinal, patient-centered intervention that offers support for a defined set of health services. In this randomized controlled trial, pregnant women who are randomized to receive antenatal patient navigation will be compared to pregnant women who are randomized to receive usual care. Navigators will support pregnant women from before 20 weeks of gestation through 2 weeks postpartum. The PATH intervention will be grounded in understanding and addressing factors that influence health and access to care in order to promote self-efficacy, enhance access, and sustain long-term engagement.\n\nThe main objectives of the study are to:\n\n1. Evaluate whether PATH, compared to usual care, improves maternal health outcomes. We hypothesize the PATH model of antenatal patient navigation for low-income women will reduce the incidence of a composite of adverse maternal outcomes, all of which are known to be increased among women with barriers to care.\n2. Evaluate whether PATH, compared to usual care, improves perinatal health outcomes. We hypothesize PATH will reduce the incidence of a composite of adverse perinatal outcomes. We will also investigate neonatal\u002Fpediatric health care utilization.\n3. Evaluate patient, clinician, navigator, and healthcare system experiences with PATH in preparation for widespread implementation and dissemination of the PATH obstetric navigation model. This aim will be accomplished through investigating patient-reported outcomes, completing qualitative and process mapping interviews with navigated participants, and completing qualitative and process mapping interviews with clinicians, navigators, and health administrators.",[78,28,79,80,81],"Maternal Morbidity","Neonatal Morbidity","Retention in Care","Prenatal Care","2026-04-02",{"date":84,"type":55},"2026-04-06",{"date":86,"type":55},"2025-10-06",{"date":88,"type":22},"2030-06-01",{"name":90,"class":62},"Northwestern University",{"id":92,"slug":93,"hasResults":11,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":97,"eligibilityCriteria":98,"healthyVolunteers":17,"sex":18,"minAge":99,"maxAge":72,"enrollmentInfo":100,"targetDuration":4,"studyType":23,"phases":102,"briefSummary":103,"conditions":104,"keywords":107,"overallStatus":118,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":63},"100590958","ai-powered-cura-application-for-identifying-at-risk-pregnancies-in-obstetric-management-100590958","NCT06974188","AI-Powered CURAᵀᴹ Application for Identifying At-Risk Pregnancies in Obstetric Management","AI-Powered CURAᵀᴹ Application for Identifying At-Risk Pregnancies in Obstetric Management: A Randomized Controlled Trial (CURAte)","CURAte","Inclusion Criteria:\n\n* Age: 21 years old to 50 years old\n* Singleton Pregnancy\n* No more than 13 weeks' and 6 days' gestation at recruitment\n* Able to provide written, informed consent\n\nExclusion Criteria:\n\n* Not proficient in the English language (AI intervention is only available in English at this stage)","21 Years",{"count":101,"type":22},1700,[25],"It is important to identify high pregnancies early through screening so that appropriate care and intervention may be instituted. An AI-assisted risk categorisation approach may be advantageous compared with traditional means of screening. The purpose of this study is to determine if the adoption of an AI-assisted approach in general pregnancy risk screening will improve the accuracy of antenatal risk categorization into high- and low- risk pregnancy groups, ultimately resulting in fewer poor maternal and fetal\u002Fneonatal outcomes.",[105,106,28],"High-risk Pregnancy","Pregnancy",[108,109,110,111,112,113,114,115,116,117],"Machine-learning","Artificial Intelligence","Antenatal Risk Stratification","Software as a Medical Device","Machine Learning Algorithm","Pregnancy Complications","Neonatal Complications","Pregnancy outcomes","Obstetric complications","Antenatal care","NOT_YET_RECRUITING","2025-07-14",{"date":121,"type":55},"2025-07-15",{"date":123,"type":22},"2025-08",{"date":125,"type":22},"2027-03",{"name":127,"class":62},"National University Hospital, Singapore"]