[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anterior-cruciate-ligament-acl-reconstruction-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anterior-cruciate-ligament-acl-reconstruction-surgery":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100633220","effect-of-graft-type-on-knee-muscle-strength-after-acl-reconstruction-100633220",false,"NCT07523854","Effect of Graft Type on Knee Muscle Strength After ACL Reconstruction","Effect of Graft Type on Knee Muscle Strength Development After Anterior Cruciate Ligament Reconstruction","GRAFT-ACL","Inclusion Criteria:\n\n* Age 13 to 45 years\n* Undergoing anterior cruciate ligament reconstruction with either hamstring tendon autograft or quadriceps tendon autograft\n* Unilateral anterior cruciate ligament injury\n* Complete ACL tear with accompanying minimal collateral ligament injury and first-degree meniscal tear\n* Tegner Activity Score of 5 or higher\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Anterior cruciate ligament reconstruction with patellar tendon autograft or allograft\n* Revision surgery\n* Systemic or neurological disease\n* Multiple ligament injuries\n* Grade III lateral or medial collateral ligament tear or significant articular cartilage lesion\n* Failure to regularly attend the rehabilitation program during the first 3 postoperative months\n* History of lower extremity injury in the contralateral limb within the last 12 months\n* Hypertension, cardiovascular disease, peripheral vascular disease, history of deep vein thrombosis, neurological disease, systemic inflammation, diabetes, cancer, or obesity","ALL","13 Years","45 Years",{"count":21,"type":22},80,"ESTIMATED","OBSERVATIONAL","This prospective observational study will compare recovery after anterior cruciate ligament reconstruction using quadriceps tendon autograft or hamstring tendon autograft. The main goal is to examine differences in knee muscle strength recovery during the early and mid-term postoperative period. Participants aged 13 to 45 years who undergo unilateral ACL reconstruction and meet the eligibility criteria will be followed at Hacettepe University. Knee extensor and flexor strength will be assessed using isometric testing at postoperative weeks 4, 8, and 12 and month 6, and with isokinetic concentric testing at months 3 and 6. Functional outcomes and kinesiophobia will also be evaluated at month 6 using IKDC, KOOS, and the Tampa Scale for Kinesiophobia. All participants will receive the same standard postoperative rehabilitation program under physiotherapist supervision. The study aims to clarify whether graft type is associated with different patterns of muscle strength recovery and functional improvement after ACL reconstruction",[26,27,28],"Anterior Cruciate Ligament Reconstruction Rehabilitation","Strength Outcomes","Anterior Cruciate Ligament (ACL) Reconstruction Surgery",[30,31,32,33,34],"ACL reconstruction","quadriceps tendon autograft","hamstring tendon autograft","knee muscle strength","rehabilitation","RECRUITING","2026-04-11",{"date":38,"type":39},"2026-04-15","ACTUAL",{"date":41,"type":39},"2026-01-23",{"date":43,"type":22},"2027-02-25",{"name":45,"class":46},"Hacettepe University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":63,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":47},"100599909","kronos-versus-breg-t-scope-post-operative-knee-braces-following-anterior-cruciate-ligament-acl-reconstruction-100599909","NCT07090616","KRONOS Versus Breg T-Scope Post-operative Knee Braces Following Anterior Cruciate Ligament (ACL) Reconstruction","A Randomized Controlled Trial of the KRONOS Versus Breg T-Scope Post-operative Knee Braces Following Anterior Cruciate Ligament (ACL) Reconstruction","Inclusion Criteria:\n\n* Subjects \\> 18 years of age\n* English-speaking\n* Scheduled to undergo primary anterior cruciate ligament reconstruction surgery\n* No history of prior knee surgery on the operative knee\n* No concomitant ligamentous repair or reconstruction procedures (i.e. ligamentous pathology aside from anterior cruciate ligament).\n* Subjects undergoing concurrent partial meniscectomy or meniscus repair that would not alter postoperative weight-bearing status or rehabilitation protocol would be eligible for inclusion.\n* Clinical and radiographic examination (MRI) consistent with an acute full thickness ACL tear\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years of age\n* Non-English speaking\n* Revision ACL reconstruction\n* Multi-ligamentous injury, including concomitant posterior cruciate ligament, medial collateral ligament and fibular collateral ligament injuries\n* Concomitant meniscal or cartilage injury that would alter postoperative weight bearing status or rehabilitation protocol\n* Inability to comply with the proposed follow-up clinic visits\n* Subjects lacking decisional capacity\n* Worker's compensation subjects\n* Requiring a custom-sized brace","18 Years",{"count":57,"type":22},40,"INTERVENTIONAL",[60],"NA","The purpose of this study is to evaluate how well the KRONOS postoperative knee brace reduces pain and enhances recovery compared with the standard Breg T-scope hinged brace following anterior cruciate ligament (ACL) reconstruction knee surgery.",[28],[64,65],"Braces","Anterior cruciate ligament (ACL) reconstruction surgery","2026-02-11",{"date":68,"type":39},"2026-02-12",{"date":70,"type":39},"2025-02-11",{"date":72,"type":22},"2028-01",{"name":74,"class":46},"Rush University Medical Center"]