[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anthracycline\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anthracycline":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100585127","cardiac-injury-due-to-anthracycline-in-paediatric-oncological-patients-100585127",false,"NCT06898320","Cardiac Injury Due to Anthracycline in Paediatric Oncological Patients","Prediction of Cardiac Injury Due to Anthracycline Chemotherapy in Paediatric Oncological Patients Using Advanced Echocardiography and Circulating Biomarkers.","Inclusion Criteria:\n\n* Paediatric oncological patients 0-18 years\n* Planned start of anthracycline therapy\n* Normal left ventricular systolic function according to International Guidelines before the treatment with AC\n\nExclusion Criteria:\n\n* Previous anthracycline treatment, bone marrow transplantation or chest radiation\n* Pre-anthracycline treatment echocardiographic evidence of:\n* More than mild pericardial effusion\n* More than mild mitral regurgitation\n* Poor echocardiographic acoustic window","ALL","0 Years","18 Years",{"count":20,"type":21},22,"ESTIMATED","OBSERVATIONAL","The study investigates the role of echocardiography and of serum biomarkers (NT-proBNP, cardiac Troponin-I) in predicting cardiac injury in a cohort of paediatric oncological patients treated with Anthracycline chemotherapy.",[25,26],"Heart Injuries","Anthracycline",[28,29,30,31],"Cardiac injury","Anthracycline chemotherapy","echocardiography","Circulating biomarkers","RECRUITING","2025-05-06",{"date":35,"type":36},"2025-05-09","ACTUAL",{"date":38,"type":36},"2023-07-21",{"date":40,"type":21},"2033-07-21",{"name":42,"class":43},"IRCCS Burlo Garofolo","OTHER"]