[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"antibiotic-use\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:antibiotic-use":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,66,96,130],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":44,"overallStatus":53,"whyStopped":4,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":65},"100636706","improved-child-nutrition-and-development-through-social-transfers-100636706",false,"NCT07569172","Improved Child Nutrition and Development Through Social Transfers","Taabo Enhanced Nutrition and Development Through Economic Rewards","TENDER","Inclusion Criteria:\n\n1. Are enrolled in the Taabo multigenerational birth cohort (MGC)\n2. Completed the postpartum interview of the Taabo MGC\n3. Have a child who is within two weeks of their 12-month birthday,\n4. are breastfeeding at time of recruitment,\n5. live in the Taabo HDSS, Côte d'Ivoire\n6. have no illnesses that contraindicates breastfeeding,\n7. had a healthy singleton infant with a birth weight of at least 2500 grams, and\n8. agree to participate and sign an informed consent; if underage (12-17 years), a legal representative will also have to agree to sign the informed consent\n\nExclusion Criteria:\n\n1. Plans to move permanently outside study area\n2. Has a medical, intellectual or psychological disability\n3. Contraindication for breastfeeding\n4. Children born with \\\u003C 2500 grams","FEMALE","12 Years",{"count":20,"type":21},1040,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to learn if a conditional social transfer works to improve rates of complementary breastfeeding. It will also learn about the impacts of social transfers on maternal and child health and development. The main questions it aims to answer are:\n\n* Does the social transfer increase complementary breastfeeding rates at 24-months postpartum?\n* Does the social transfer increase complementary breastfeeding duration?\n* Does the social transfer impact child health and development?\n* Does the social transfer impact maternal physical and mental health?\n\nResearchers will compare a conditional social transfer to a control group that only receives education about breastfeeding recommendations to see if a conditional social transfers works to increase complementary breastfeeding.\n\nParticipants will:\n\nReceive a pamphlet explaining the current recommendations of breastfeeding Receive instructions that if they meet the recommendation to breastfeed until 24-months postpartum they receive a social transfer or receive no additional information Complete home visits at 12- and 24-months postpartum Complete detailed questionnaire",[27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43],"Breastfeeding","Breastfeeding Education","Breastfeeding Duration","Breastfeeding Continuation","Child Growth","Stress","Infectious Diseases","Anemia","Child Development","Weight Loss","Blood Pressure","Mental Health","Diarrhea","Coughing","Eczema","Allergies","Antibiotic Use",[45,46,47,48,49,50,51,52],"breastfeeding","cash transfer","child health","maternal health","mental health","child growth","child development","education","NOT_YET_RECRUITING","2026-04-28",{"date":56,"type":57},"2026-05-06","ACTUAL",{"date":59,"type":21},"2026-06-01",{"date":61,"type":21},"2028-02-28",{"name":63,"class":64},"Swiss Tropical & Public Health Institute","OTHER",1,{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":4,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":22,"phases":78,"briefSummary":79,"conditions":80,"keywords":81,"overallStatus":53,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":4},"100601535","testing-interventions-designed-to-improve-how-members-of-the-general-public-follow-instructions-to-take-antibiotics-100601535","NCT07111754","Testing Interventions Designed to Improve How Members of the General Public Follow Instructions to Take Antibiotics","How Can Behavioural Intent to Take Antibiotics \"Exactly as Prescribed\" be Increased? An Online Randomised Behavioural Experiment","Inclusion Criteria:\n\n* Adults aged 18 and over\n* United Kingdom residents\n* Have passed the attention check at the start of the online survey.\n\nExclusion Criteria:\n\n* Individuals who are not signed up a market research panel and therefore will not have access to the online survey.\n* Those resident outside the UK.\n* Those who fail the attention check at the start of the online survey. Individuals aged under 18.",true,"ALL","18 Years",{"count":77,"type":21},7000,[24],"Antimicrobial resistance (AMR) is a global public health challenge. Due to overuse of antibiotics, bacteria are becoming resistant to antibiotics, which creates infections that can't be treated by modern medicine. To combat AMR, the public need to both know that AMR is an issue and know what actions they can take to address AMR.\n\nWhen patients are prescribed antibiotics, the information provided (and how this is provided) is likely to be influential on whether they are taken correctly, or if behaviours that contribute to antimicrobial resistance (such as not finishing the course) predominate.\n\nThis study, a large online experiment involving 7,000 people across the UK, aims explore the influence of what information and how it is provided. The study looks at different ways of presenting information on antibiotic packets-from clear instructions to warnings and even scannable QR codes with extra details.\n\nThe main goals are to see if these changes can help participants understand how to take antibiotics exactly as prescribed. The investigators also want to see if it helps participants understand what antibiotic resistance is and their role in preventing it.\n\nBy understanding what works best, the investigators hope to find simple, effective ways to help everyone use antibiotics wisely, protecting these vital medicines for the future.",[43],[82,83,84,85,86],"Antibiotics","Behaviour Change","Randomised controlled trial","Antibiotic Resistance","Antimicrobial Resistance","2025-08-05",{"date":89,"type":57},"2025-08-08",{"date":91,"type":21},"2025-08-31",{"date":93,"type":21},"2026-03-01",{"name":95,"class":64},"Imperial College London",{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":102,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":74,"minAge":75,"maxAge":4,"enrollmentInfo":104,"targetDuration":4,"studyType":22,"phases":106,"briefSummary":107,"conditions":108,"keywords":116,"overallStatus":53,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":65},"100593147","clinical-impact-of-surgical-wound-morbidity-according-to-the-type-of-saphenous-vein-harvesting-technique-endoscopic-vs-open-in-patients-undergoing-myocardial-revascularization-surgery-100593147","NCT07002658","Clinical Impact of Surgical Wound Morbidity According to the Type of Saphenous Vein Harvesting Technique (Endoscopic vs. Open) in Patients Undergoing Myocardial Revascularization Surgery","Endoscopic Saphenous Vein Harvesting Versus Conventional Open Harvesting in Patients Undergoing Coronary Artery Bypass Grafting, Either Alone or in Combination With Another Cardiac Surgical Procedure, in Terms of the Clinical Impact of Surgical Wound Morbidity","EndOSiC","Inclusion Criteria:\n\n* Patients undergoing coronary artery bypass grafting (CABG), alone or in combination with other surgery (valve or arrhythmia surgery), with or without cardiopulmonary bypass (CPB), in which preoperative evaluation includes the plan to use a short saphenous vein segment (alone or in addition to arterial conduits).\n* Availability of a surgeon or cardiac surgery resident trained in endoscopic harvesting in the operating room.\n* Patients undergoing myocardial revascularization surgeries with or without extracorporeal circulation.\n* Patients undergoing concomitant cardiac valve replacement surgery, atrial fibrillation surgery, and others, in addition to CABG\n\nExclusion Criteria:\n\n* Emergent surgery or procedures performed during cardiorespiratory arrest\n* Myocardial revascularization with arterial grafts only\n* Presence of varicose veins\n* History of infrainguinal vascular surgery\n* Presence of ulcers and\u002For active infection in the lower limbs\n* Previous stroke with neurological sequelae in the legs\n* History of deep vein thrombosis in the legs\n* Pregnancy\n* Age under 18 years\n* Lack of signed informed consent",{"count":105,"type":21},356,[24],"The goal of this clinical trial is to compare two different techniques: endoscopic saphenous vein harvesting versus conventional open harvesting in patients undergoing coronary artery bypass grafting, either alone or in combination with another cardiac surgical procedure (valve surgery or arrhythmia surgery). The main questions the trial aims to answer are:\n\nDoes the endoscopic technique reduce surgical wound morbidity in terms of shorter hospital stays? Does endoscopic saphenous harvesting reduce the use of antibiotics for saphenectomy wound infections? Does the endoscopic technique reduce need for wound dressings due to necrosis and\u002For wound infection, and reduce need for analgesic treatment for wound pain? This prospective, randomized study will be conducted in the Cardiovascular Surgery Service at Hospital Clínico San Carlos.\n\nParticipants will be randomly assigned to a different saphenectomy technique. All patients will be assessed for saphenectomy wound complications upon discharge, and by phone call at 7 days, 1 month, and 3 months following the intervention.",[109,110,111,112,43,113,114,115],"CABG-patients","Saphenectomy","Endoscopic Surgery","Wound Complications","Cardiac Surgery","Off Pump Coronary Artery Bypass Graft","Coronary Artery Bypass Graft With or Without ECC",[117,118,119,120],"endoscopic vein harvesting","CABG surgery","open vein harvesting","wound morbidity","2025-06-03",{"date":123,"type":57},"2025-06-06",{"date":125,"type":21},"2025-07-01",{"date":127,"type":21},"2026-08-01",{"name":129,"class":64},"Hospital San Carlos, Madrid",{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":134,"acronym":4,"eligibilityCriteria":135,"healthyVolunteers":73,"sex":74,"minAge":4,"maxAge":4,"enrollmentInfo":136,"targetDuration":4,"studyType":22,"phases":138,"briefSummary":139,"conditions":140,"keywords":141,"overallStatus":145,"whyStopped":4,"lastUpdateSubmitDate":146,"lastUpdatePostDateStruct":147,"startDateStruct":149,"completionDateStruct":151,"leadSponsor":153,"locationsCount":65},"100390007","generating-collective-solutions-to-reduce-unnecessary-antibiotic-use-in-vietnam-100390007","NCT04358289","Generating Collective Solutions to Reduce Unnecessary Antibiotic Use in Vietnam","For communities:\n\nInclusion criteria:\n\n* Commune officials consent to take part;\n* Have a commune population larger than 3000 individuals;\n* Have active Women's Union and Farmers' Union groups with a paid commune-level representative;\n* Commune health centre has a doctor;\n* Commune health centre has electronic database.\n\nExclusion criteria:\n\n* Urban areas with a low proportion of farmers or low utilisation of CHCs for primary healthcare.\n\nFor study participants:\n\nInclusion criteria:\n\n* Participant is willing and able to give informed consent for participation in the study;\n* Community members normally resident in the study commune (living in the study commune and resident for at least three months);\n\nExclusion criteria:\n\n* No one will be actively excluded from participating in this population-based study.\n\nFor Commune Health Centers:\n\nInclusion criteria:\n\n* Serve a commune population larger than 3000 individuals;\n* Have an average caseload of at least 10 consultations per facility per week for ARI verified by checking the database system of the provincial centre for disease control and prevention (CDC) where the implementation study is being conducted;\n* Health centre doctor is normally employed at the centre and has been there for at least three months.\n\nExclusion criteria:\n\n* Low antibiotic prescription rate for ARI of below 40%.\n\nFor Patient records:\n\nInclusion criteria:\n\n* All patients' anonymised records.\n\nExclusion criteria:\n\n* Don't have national health insurance\u002Fnot recorded.",{"count":137,"type":21},3315,[24],"The study aims to develop community-based interventions targetting inappropriate antibiotic dispensing and use behaviours in rural Vietnam and has 3 research components.\n\nCommunity and primary healthcare interventions: The investigators will conduct a four-armed cluster randomised controlled trial. The first arm will be a control arm with no interventions. The second intervention arm will have a basic antimicrobial stewardship intervention, involving working with the Ministry of Health, Medical Services Administration to revise guidelines for antibiotic prescribing for acute respiratory infections (ARI) in primary care, and then training primary healthcare doctors in their use. The third intervention arm will have basic antimicrobial stewardship guidelines and training for primary healthcare doctors, plus educational materials for the community, disseminated through posters, leaflets and local media channels. The fourth intervention arm will use a participatory action research approach to engage primary healthcare doctors and communities, in addition to the basic guidelines and training materials. The participatory action research approach will train local facilitators to lead community and health-worker groups through a cycle of problem identification, strategy development, implementation and review, focusing on inappropriate human and small-scale agricultural use of antibiotics.\n\nHospital interventions: The investigators will work with Provincial and District Hospitals serving these communities to implement quality improvement cycles for antibiotic stewardship, also using a participatory action research approach. This will also follow a cycle of a cycle of problem identification, strategy development, implementation and review.",[43],[142,143,144],"AMR","primary health care","Antimicrobial resistance","RECRUITING","2023-12-05",{"date":148,"type":57},"2023-12-06",{"date":150,"type":57},"2020-02-27",{"date":152,"type":21},"2026-09",{"name":154,"class":64},"Oxford University Clinical Research Unit, Vietnam"]