[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"antisocial-behavior\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:antisocial-behavior":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100591509","matching-treatments-to-cognitive-deficits-in-offenders-with-substance-use-disorders-100591509",false,"NCT06981351","Matching Treatments to Cognitive Deficits in Offenders With Substance Use Disorders","MCT","Inclusion Criteria:\n\n* Currently incarcerated\n* No uncorrectable auditory or visual deficits\n* Able to speak and\u002For understand English\n* 5th grade reading level or higher\n* IQ score = 80 or above\n* Lifetime history of substance use disorder based on DSM criteria\n* No history of dementia or other cognitive disability\n* No indication of current psychotic disorder\n* No major medical illness or CNS disease\n* Scores from the Psychopathy Checklist-Revised (PCL-R) meet criteria for one of the designated treatment groups\n\nExclusion Criteria:\n\n\\-","MALE","18 Years","55 Years",{"count":20,"type":21},288,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to investigate the effect of two types of cognitive remediation training on real-world behavioral outcomes including substance use, institutional adjustment, and recidivism following release from prison. Each training type is designed to target one of two subtypes of antisocial criminal offenders, who are characterized by either: 1) Attention to context-based deficits, or 2) Affective cognitive control-based deficits.\n\nThe main questions it aims to answer are:\n\nDoes matching deficit type with targeted cognitive training improve outcomes (relative to mismatched training)? What are the functional brain mechanisms that underlie treatment change?\n\nParticipants will:\n\nBe assigned to cognitive training that either does or does not match their deficit type.\n\nComplete six one-hour sessions of cognitive skills training. Complete pre and post-training behavioral tasks assessing self-regulation deficits.\n\nComplete structural MRI scans and functional MRI scans assessing cognitive control.\n\nComplete post-treatment follow-up assessments evaluating self-regulation, adjustment, and stressful life events, substance use and recidivism.",[27],"Antisocial Behavior",[29,30,31],"Cognitive skills training","Attention to Context","Affective Cognitive Control","RECRUITING","2025-05-12",{"date":35,"type":36},"2025-05-20","ACTUAL",{"date":38,"type":36},"2025-03-18",{"date":40,"type":21},"2029-05-31",{"name":42,"class":43},"The Mind Research Network","OTHER"]