[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anxiety-disorder-of-adolescence\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anxiety-disorder-of-adolescence":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,56],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":4},"100638235","co-designing-adaptations-of-a-digital-mental-health-intervention-wysa-for-adolescent-girls-with-anxiety-or-depression-in-rural-india-100638235",false,"NCT07595029","Co-designing Adaptations of a Digital Mental Health Intervention (Wysa) for Adolescent Girls With Anxiety or Depression in Rural India","Identifying Barriers and Enablers to Co-Design Adaptations of a Digital Mental Health Intervention (Wysa) for Adolescent Girls in Low Resource Settings in Uttar Pradesh, India","ADOLESCENTS:\n\nInclusion Criteria:\n\n* Sex: girls\n* Marital status: Unmarried\n* Are between 13-18 years of age\n* Residing in the selected villages of Uttar Pradesh, India.\n* Have elevated anxiety and\u002For depressive symptoms on the RCADS-25.\n* Have access to a mobile phone (at least 1 mobile phone within the family).\n* Provide assent\u002F consent to participate, along with guardian consent for minors.\n\nAdolescents Exclusion Criteria:\n\n* Adolescent girls who have difficulties that would prevent them from actively participating in workshop activities (e.g. with memory or comprehension, indications of psychoses)\n* Are currently or have been in the past a girl icon in the Milaan Foundation Girl Icon program\n\nPARENTS\u002FGUARDIANS:\n\n1. Inclusion Criteria\n\n   * Are guardians or caregivers of a participating adolescent girl.\n   * Currently reside in Uttar Pradesh\n   * Provide informed consent to participate.\n2. Exclusion Criteria ● They have difficulties that would prevent them from actively participating in workshop activities (e.g. with memory or comprehension, indications of psychoses).\n\nCOMMUNITY STAKEHOLDERS \\& DECISION MAKERS\n\n1. Inclusion criteria\n\n   * Contribute to and influence local health related-decisions or services.\n   * Provide informed consent to participate.\n2. Exclusion Criteria ● Stakeholders who have difficulties that would prevent them from actively participating in workshop activities (e.g. with memory or comprehension, indications of psychoses)",true,"ALL","13 Years",{"count":20,"type":21},179,"ESTIMATED","OBSERVATIONAL","The goal of this study is to culturally and contextually adapt Wysa, an evidence-based AI-powered digital mental health intervention (DMHI), for adolescent girls (ages 13-18) with symptoms of anxiety and\u002For depression in rural Uttar Pradesh, India.\n\nMore specifically, the aims of this study are to (i) explore key barriers and facilitators to adoption, engagement, and usability of a digital mental health intervention (Wysa) in this setting, and to (ii) co-design contextually appropriate app adaptations and implementation strategies in collaboration with adolescent girls, their parents\u002Fguardians, and community stakeholders. At the end of this study, we would have co-developed a roadmap of potential adaptations to Wysa with implementation strategies to iteratively test and develop during the next phases of the study.",[25,26,27],"Anxiety","Depression in Adolescence","Anxiety Disorder of Adolescence",[29,30,25,31,32,33,34,35,36,37,38,39,40,41,42,43,44],"Digital Mental Health","Adolescent Mental Health","Depression","Rural Population","India","Implementation Science","Patient Engagement","Early Intervention, Psychological","Chatbot","Low-Resource Settings","Adolescent Girls","Artificial Intelligence","Cultural Adaptation","Cognitive Behavioural Therapy","Wysa","Mental Health Access","NOT_YET_RECRUITING","2026-05-12",{"date":48,"type":49},"2026-05-19","ACTUAL",{"date":51,"type":21},"2026-05",{"date":53,"type":21},"2026-11",{"name":43,"class":55},"INDUSTRY",{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":11,"sex":17,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":4,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":83},"100609854","parent-based-treatment-for-adolescent-anxiety-100609854","NCT07219992","Parent-Based Treatment for Adolescent Anxiety","Testing a Novel Parent-Based Treatment for Adolescent Anxiety Disorders","Inclusion Criteria:\n\n* Meet criteria for a primary DSM-5 AD, including separation anxiety disorder, social anxiety disorder, generalized anxiety disorder, specific phobia, panic disorder, and agoraphobia (determined by the ADIS-C\u002FP).\n* Cease all other psychosocial treatment, upon consultation with the project staff and service provider.\n* Not currently use any psychotropic medication, other than a stable dose (i.e., same dose for a minimum of 6 months prior to enrollment; no changes during course of the study) of a stimulant medication or selective serotonin reuptake inhibitor (SSRI).\n* Have an eligible and willing participating parent (see parent exclusions below).\n\nExclusion Criteria:\n\nAdolescent:\n\n* Meet criteria for any DSM-5 disorder more impairing than the most impairing AD (determined by the ADIS-C\u002FP).\n* Have any of the following disorders: autism spectrum disorder; intellectual disability; neurocognitive disorders; bipolar disorder; schizophrenia and other psychotic disorders; and alcohol and substance use disorders (determined by the Health History Form and ADIS-C\u002FP).\n* Report a suicide attempt in the last 3 months, or current suicide intent and plans (determined by the ASQ).\n* Be a victim of past or present undisclosed abuse requiring investigation or ongoing supervision by the Department of Social Services.\n* Not have sufficient proficiency with the English language to complete assessments.\n\nParents:\n\n* Have any of the following: intellectual disability; neurocognitive disorders; untreated bipolar disorder; untreated schizophrenia and other psychotic disorders; and untreated alcohol and substance use disorders (determined by the Health History Form).\n* Not be living with the adolescent at least 50% of the time for at least one year prior to enrollment.\n* Not have sufficient proficiency with the English language to complete assessments and treatment.","14 Years","17 Years",{"count":66,"type":21},108,"INTERVENTIONAL",[69],"NA","This study aims to test the efficacy of a parent-only approach to treating anxiety disorders in adolescents: SPACE (Supportive Parenting for Anxious Childhood Emotions). The comparator is another parent-based approach, PES (Parent Education and Support). The study design is a randomized controlled trial with 2 treatment arms and 3 assessment points (pre, post, and follow-up) using questionnaire data and clinical interviews.",[27],"RECRUITING","2025-11-20",{"date":75,"type":49},"2025-11-21",{"date":77,"type":49},"2025-11-01",{"date":79,"type":21},"2028-11",{"name":81,"class":82},"Yale University","OTHER",1]