[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anxiety-disorder-of-childhood\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anxiety-disorder-of-childhood":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,52,83],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":4},"100588854","implementation-of-a-just-in-time-adaptive-intervention-for-adolescent-anxiety-100588854",false,"NCT06946823","Implementation of a Just-In-Time Adaptive Intervention for Adolescent Anxiety","Community-Engaged Design and Implementation of a Just-In-Time Adaptive Intervention (JITAI) to Improve Adolescent Anxiety in Rural Populations","Inclusion Criteria:\n\n* Adolescent (age 13-17 years old)\n* New Hampshire resident\n* Fluency in English\n* Able to provide assent\n* At least mild (≥5) anxiety based on the GAD-7 assessment\n\nExclusion Criteria:\n\n* Under 13 years old\n* Over 17 years old\n* Not a New Hampshire resident\n* Unable to provide assent\n* Less than mild (\\\u003C5) anxiety based on the GAD-7 assessment","ALL","13 Years","17 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to evaluate a smartphone based just-in-time adaptive intervention (JITAI) tool to deliver somatic behavioral recommendations for anxiety management among youth. The main questions it aims to answer are:\n\n* Is the JITAI tool acceptable among the adolescent study population?\n* Is the JITAI tool feasible to deliver to the adolescent study population?\n* Does the study support preliminary efficacy of the JITAI tool among the adolescent study population?\n\nThe tool will be pilot-tested among a sample of 50 rural adolescents experiencing elevated anxiety levels who will be randomly assigned to the JITAI tool or a waitlist control, for a treatment period of 3 months.\n\nParticipants will be asked to:\n\n* Use the smartphone based JITAI tool which will deliver somatic behavioral recommendations intended to manage anxiety levels for a treatment period of 3 months\n* Respond to the tool's prompts on a daily basis and follow the delivered behavioral recommendations\n* Complete anxiety and interoception assessments at study start, study end (3 months), and one-month follow-up\n* Complete usability and user experience instruments at study end (3 months)",[27,28,29],"Anxiety","Anxiety Disorders","Anxiety Disorder of Childhood",[27,31,32,33,34,35,36,37,38,39],"Just-In-Time Adaptive Intervention","Smartphone","Behavioral Health","Community-Engaged Research","Adolescents","Rural","Digital Intervention","Participatory Design","Somatic","NOT_YET_RECRUITING","2026-04-01",{"date":43,"type":44},"2026-04-02","ACTUAL",{"date":46,"type":21},"2027-01",{"date":48,"type":21},"2027-05",{"name":50,"class":51},"Trustees of Dartmouth College","OTHER",{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":16,"minAge":59,"maxAge":17,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":82},"100583922","vr-homework-exercises-for-selective-mutism-treatment-100583922","NCT06882629","VR Homework Exercises for Selective Mutism Treatment","The Effect of Virtual Reality Homework Exercises As an Add-On to Behavioral Therapy for Children with Selective Mutism","Inclusion Criteria:\n\n* The child meets the DSM-5 criteria for SM (as a primary classification).\n* The child is attending primary school.\n* Referred to an academic center for Child and Adolescent Psychiatry (Levvel) for diagnosis and treatment of SM\n* Psychiatric comorbidity is permitted, given that SM is the primary treatment target.\n* Medication use is permitted, if stable for at least 4 weeks prior to the start of treatment.\n\nExclusion Criteria:\n\n* No participating parents.\n* Parents do not have sufficient mastery of the Dutch language.\n* Parents or child have an estimated IQ below 75.\n* The child needs inpatient treatment.\n* Children with a (medical) condition that is a contraindication for using a VR headset (epilepsy, claustrophobia, facial condition, sensitive vestibular system, panic attacks)\n* Parents receiving parental guidance which is not part of the standard treatment program.\n* Children that have received protocolled behavior therapy for SM in the past 12 months.","4 Years",{"count":61,"type":21},15,[24],"Selective mustism (SM) is an anxiety disorder that manifests in childhood. Children with Children with SM do not speak in certain social situations where this is expected of them. For example, a child may talk at home, but is afraid to speak at school. The goal of this clinical trial is to determine the efficacy of behavioral therapy for children with selective mutism (SM) combined with virtual reality (VR) homework exercises. Virtual Reality Exposure is an effective treatment for adults with anxiety disorders.\n\nThe main questions to answer are:\n\n* Is behavioral therapy combined with VR homework exercises effective in the treatment of SM?\n* Which familial factors contribute to a positive treatment outcome and homework adherence?\n\nA single-case experimental design (SCED) will be used to evaluate the efficacy of the treatment. The child's speaking behavior at baseline will be compared to the child's speaking behavior in the different phases of the intervention.\n\nParticipants will:\n\n* Follow individual therapy sessions at school.\n* Practice with the VR homework exercises at least once a week.\n* Parents and teachers will evaluate the child's speaking behavior.",[65,29],"Selective Mutism",[67,68,69,70,71,27],"Virtual reality","Virtual reality exposure therapy","Intervention","Treatment","Children","RECRUITING","2025-03-17",{"date":75,"type":44},"2025-03-18",{"date":77,"type":21},"2025-03",{"date":79,"type":21},"2027-06",{"name":81,"class":51},"Luuk Stapersma",1,{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":16,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":22,"phases":94,"briefSummary":95,"conditions":96,"keywords":97,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":112},"100415762","efficacy-trial-of-the-calm-intervention-100415762","NCT04693858","Efficacy Trial of the CALM Intervention","Enhancing the Capacity of School Nurses to Reduce Excessive Anxiety in Children: an Efficacy Trial of the CALM Intervention","Student Inclusion Criteria:\n\n* Be between the ages of 5-12\n* Have elevated anxiety symptoms as indicated by a) a total SCARED score of 15 or higher based on parent and\u002For child report using the full SCARED from the baseline evaluation, and\u002For b) a Clinician Severity Rating of 3 or higher on any anxiety diagnosis from the Anxiety Disorders Interview Schedule for Children DSM-V (ADIS)\n* Be fluent in English in order to provide informed consent and assent for their participation and to complete the study measures.\n* Children on a stable dose of pharmacological\u002Fpsychotherapeutic treatment will be eligible as long as the dose has been stable for at least 4 weeks and no changes are considered for the duration of the intervention phase of the study (8 weeks)\n\nStudent Exclusion Criteria:\n\n* Children who do not meet the inclusion criteria\n\nNurse Inclusion Criteria:\n\n* Nurses must be a Registered Nurse (RN) or another similar medical professional\n* Nurses must be work in the role of a school nurse\n* Nurses must be fluent in English","5 Years","12 Years",{"count":93,"type":21},218,[24],"Excessive anxiety among elementary students is highly prevalent and associated with impairment in academic, social, and behavioral functioning. The primary aim of this project is to evaluate the initial efficacy of a brief nurse-delivered intervention (CALM: Child Anxiety Learning Modules), relative to a credible comparison (CALM-R, relaxation skills only) and a waitlist control for reducing anxiety symptoms and improving education outcomes at post intervention and at a 1-year follow-up. In addition, the research team will assess the cost effectiveness of CALM versus CALM-R and the waitlist control and examine potential predictors, moderators, and mediators of CALM's impact on child outcomes based on the proposed theory of change.",[29],[27,98,99,100,101,102],"Child anxiety","School-based interventions","School nursing","Brief anxiety interventions","Cognitive-behavioral therapy","2024-12-04",{"date":105,"type":44},"2024-12-09",{"date":107,"type":44},"2020-12-01",{"date":109,"type":21},"2026-07-30",{"name":111,"class":51},"UConn Health",2]