[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anxiety-sensitivity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anxiety-sensitivity":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100628212","reaching-calm-a-digital-intervention-to-prevent-perinatal-anxiety-disorders-100628212",false,"NCT07458698","Reaching Calm: A Digital Intervention to Prevent Perinatal Anxiety Disorders","Reaching Calm Pilot (K23)","Inclusion Criteria:\n\n* Receiving prenatal care at participating obstetric practice\n* Endorsed mild to moderate anxiety (GAD-7 score 5-15)\n* Currently pregnant (gestational age \\\u003C32)\n* Started Reaching Calm digital intervention, if in intervention group\n\nExclusion Criteria:\n\n* Not pregnant\n* Unable to participate in 60-minute interview\n* Unwilling to be audio recorded\n* GAD-7 \\\u003C5, or GAD-7≥15\n* Adults unable to consent (adults lacking capacity)\n* Individuals who are not yet adults (infants, children, teenagers)\n* Prisoners\n* Non-English-speaking","FEMALE","18 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to find out if a digital program called Reaching Calm can help prevent anxiety in women who are pregnant. The study will offer Reaching Calm at obstetric practices where participants receive prenatal care. The study focuses on people who may be at greater risk for experiencing anxiety during or after pregnancy. The main questions this study aims to answer are:\n\n* Is Reaching Calm easy to use and acceptable to both participants and healthcare professionals?\n* Does Reaching Calm help reduce risk for anxiety among participants?\n* Does personalizing the digital program help participants stay involved? Researchers will compare obstetric practices that offer Reaching Calm to those providing usual care.\n\nParticipants will:\n\n* Receive text messages and use a web-based platform for learning about anxiety and coping strategies\n* Respond to surveys about their experiences and symptoms\n* Some will take part in interviews and focus groups to share their views\n* Healthcare professionals will receive training on how to support the program The study will monitor how many people join, stay involved, and how the program affects their well-being. The results will help prepare for a larger study that could lead to wider use of Reaching Calm across the country.",[26,27,28],"Perinatal Anxiety","Anxiety Sensitivity","Perinatal Depression",[30,31,32,33,34],"Perinatal anxiety","Obstetric care","Perinatal mental health","Digital mental health","Engagement","NOT_YET_RECRUITING","2026-06-10",{"date":38,"type":39},"2026-06-12","ACTUAL",{"date":41,"type":20},"2026-07-01",{"date":43,"type":20},"2029-08-31",{"name":45,"class":46},"University of Massachusetts, Worcester","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":55,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":61,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100576536","interoceptive-training-enhanced-mindfulness-100576536","NCT06786572","Interoceptive Training Enhanced Mindfulness","Interoceptive Training Enhanced Mindfulness (ITEM): Acceptability and Measurement","ITEM","Inclusion Criteria:\n\n* Veteran status\n* able to read and speak English\n* ASI-3 score of 23 or higher\n* clinically meaningful distress\u002Fimpairment related to an emotional or somatic complaint as determined by a Clinical Global Impression Scale (CGI) of 3 or greater\n* Internet access via a device that can support remote study activities and ability to attend in person appointments\n\nExclusion Criteria:\n\n* serious mental illness, including bipolar disorder or psychotic illness\n* current, untreated alcohol or substance use disorder\n* moderate-severe suicidality that would likely result in the need for urgent intervention in the next 2 months\n* current regular meditation practice or treatment for AS-related condition\n* cognitive dysfunction that interferes with the ability to engage in treatment","ALL",{"count":57,"type":20},48,[23],"This pilot randomized controlled trial will compare a novel mindfulness training to interoceptive exposure to establish feasibility and acceptability as an intervention for anxiety sensitivity.",[27],[62,63,64],"anxiety sensitivity","mindfulness","interoception","RECRUITING","2026-01-28",{"date":68,"type":39},"2026-02-02",{"date":70,"type":39},"2025-09-10",{"date":72,"type":20},"2027-03-31",{"name":74,"class":46},"Veterans Medical Research Foundation",1]