[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anxiolytic-effect\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anxiolytic-effect":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":27,"conditions":28,"keywords":33,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":4},"100606787","phase-1-children-of-age-2-6years-undergoing-elective-surgery-will-be-divided-into-two-groups-randomly-this-study-aims-to-evaluate-if-intranasal-dexmedetomidine-is-better-than-intranasal-ketamine-in-producing-sedation-and-reducing-parent-separation-anxiety-before-surgery-100606787",false,"NCT07180095","Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.","Intranasal Dexmedetomidine Versus Intranasal Ketamine for Preoperative Sedation in Pediatrics","DREAM-Kids","Inclusion Criteria:\n\n* American society of Anesthesiologist (ASA) class-I and II\n* Children 2-6 years of age undergoing elective surgery\n\nExclusion Criteria:\n\n* Known hypersensitivity to study drugs\n* Refusal of consent\n* Known renal, hepatic or cardiac dysfunction\n* Nasal deformity or pathology\n* Recent upper respiratory infection (within 2 weeks)\n* Children undergoing neurosurgery or ophthalmic surgery","ALL","2 Years","6 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25,26],"PHASE1","PHASE2","This study aims to compare intranasal dexmedetomidine versus intranasal ketamine as a premedication in children undergoing surgery in our population. Hypothesis is Intranal dexmedetomidine is better than intranasal ketamine in producing preoperative sedation in pediatric patients undergoing surgery under general anesthesia.",[29,30,31,32],"Sedation","Preoperative Anxiety Experienced by the Pediatric Patient","Anxiolytic Effect","Sedation and Analgesia",[34,35,36,37],"Preoperative Sedation","Hemodynamic changes","Dexmedetomidine","Dexmedetomidine vs Ketamine","NOT_YET_RECRUITING","2025-09-11",{"date":41,"type":42},"2025-09-18","ACTUAL",{"date":44,"type":22},"2026-01-01",{"date":46,"type":22},"2026-07-30",{"name":48,"class":49},"Liaquat National Hospital & Medical College","OTHER",{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":79},"100596793","anxiolytic-effect-of-virtual-reality-immersion-versus-midazolam-premedication-in-patients-undergoing-dacryocystorhinostomy-surgery-100596793","NCT07050095","Anxiolytic Effect of Virtual Reality Immersion Versus Midazolam Premedication in Patients Undergoing Dacryocystorhinostomy Surgery","Randomized Clinical Trial for Comparison Between the Anxiolytic Effect of Virtual Reality Immersion Versus Midazolam Premedication in Patients Undergoing Dacryocystorhinostomy Surgery","Inclusion Criteria:\n\n* Aged 18-65.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) classification: I - II.\n* Patient undergoing Dacryocystorhinostomy Surgery (DCR) operation under general anesthesia.\n\nExclusion Criteria:\n\n* Patient refusal.\n* Patients with cardiac diseases.\n* Patients with renal diseases.\n* Patients with drug sensitivity and seizures.\n* Substance abuse and addiction.\n* Claustrophobia.\n* Patients with cerebrovascular disease.\n* Psychiatric and cognitive disorder.\n* Patients with severe teary eyes and blurring of vision.\n* Patients who express discomfort during the test.","18 Years","65 Years",{"count":60,"type":22},40,[62],"NA","The aim is to investigate the anxiolytic effect, and hemodynamic stability of using virtual reality immersion in adult patients undergoing Dacryocystorhinostomy (DCR) operation under general anesthesia and to compare its effect to that of using Midazolam as a premedication.",[31,65,66,67,68],"Virtual Reality Immersion","Midazolam","Premedication","Dacryocystorhinostomy","RECRUITING","2025-06-25",{"date":72,"type":42},"2025-07-03",{"date":74,"type":42},"2025-06-01",{"date":76,"type":22},"2025-12-30",{"name":78,"class":49},"Cairo University",1]