[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"aortic-valve-stenosis-and-insufficiency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:aortic-valve-stenosis-and-insufficiency":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100601213","assessment-of-coronary-artery-disease-before-transcatheter-aortic-valve-replacement-a-randomized-multicenter-non-inferiority-trial-100601213",false,"NCT07107568","Assessment of Coronary Artery Disease Before Transcatheter Aortic Valve Replacement: A Randomized, Multicenter, Non-Inferiority Trial","TAVR-CT","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Severe aortic valve stenosis and indication for intervention according to current European Society of Cardiology (ESC) guidelines\n* TAVR candidate\n* Written informed consent\n\nExclusion Criteria:\n\n* Cardiogenic shock at presentation (e.g., emergency indication for TAVR)\n* Severe renal impairment with an estimated glomerular filtration rate of \\\u003C30 mL\u002Fmin\u002F1.73 m²\n* Life expectancy \\\u003C1 year due to other severe non-cardiac disease (e.g., malignancy)\n* Pregnancy","ALL","18 Years",{"count":19,"type":20},700,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to determine whether a non-invasive coronary assessment strategy using photon-counting detector computed tomography (PCD-CT) is non-inferior to invasive coronary angiography (ICA) for evaluating coronary artery disease (CAD) prior to transcatheter aortic valve replacement (TAVR) in patients with severe aortic stenosis.",[26,27,28],"Aortic Valve Stenosis and Insufficiency","Coronary Artery Disease(CAD)","Transcatheter Aortic Valve Replacement (TAVR)",[14,30,31,32,33,34,35],"PCD-CT","Severe Aortic Stenosis","Transcatheter Aortic Valve Replacement","TAVR","Photon-Counting Detector CT","Randomized Controlled Trial","RECRUITING","2025-08-18",{"date":39,"type":40},"2025-08-22","ACTUAL",{"date":42,"type":40},"2025-08-14",{"date":44,"type":20},"2029-12-31",{"name":46,"class":47},"Medical University Innsbruck","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":61,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":48},"100545245","long-term-prognosis-and-valve-durability-of-tavr-100545245","NCT06379386","Long-term Prognosis and Valve Durability of TAVR","Long-term Prognosis and Valve Durability of Transcatheter Aortic Valve Replacement for Aortic Valve Disease: a Real-world, Prospective, Single-center, Observational Study","Inclusion Criteria:\n\nPatients diagnosed with severe aortic valve regurgitation undergo evaluation by the Heart team and are eligible for TAVR therapy.\n\n2\\. Patients who understand the purpose of this study, agree to participate in the trial and sign the informed consent form\n\n* 1\\. Patients with aortic stenosis or aortic valve insufficiency who were evaluated by the Heart team and underwent TAVR therapy\n* 2\\. Patients who understand the purpose of the study, agree to participate in the trial and sign the informed consent form\n\nExclusion Criteria:\n\n* 1\\. Patients who cannot provide informed consent\n* 2\\. Patients who are participating in other clinical trials",{"count":57,"type":20},1000,"OBSERVATIONAL","This registry aims to evaluate the long-term prognosis and valve durability of transcatheter aortic valve replacement (TAVR) in a real-world setting. Baseline characteristics, procedural data, and clinical outcomes will be collected in a prospective and observational manner.",[26],[62,33,63,64],"Aortic Valve Disease","Prognosis","Valve durability","2024-04-18",{"date":67,"type":40},"2024-04-23",{"date":69,"type":40},"2016-01",{"date":71,"type":20},"2030-12",{"name":73,"class":47},"Xijing Hospital"]