[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"aphasia-acquired\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:aphasia-acquired":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,55,85,122,149,172,202,227,257,279],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":37,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100595742","phase-2-comparing-traditional-semantic-feature-analysis-tsfa-and-semantic-feature-analysis--metacognitive-strategy-training-sfamst-100595742",false,"NCT07036406","Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)","Comparing the Effectiveness of Traditional Semantic Feature Analysis (SFA) Versus SFA Plus Metacognitive Strategy Training (SFA+MST) for People With Acquired Aphasia","Inclusion Criteria:\n\n* Have aphasia due to a single acute event (e.g., left-hemisphere stroke, traumatic brain injury)\n* Be at least six-months post aphasia-onset,\n* Be a proficient English speaker,\n* Have normal or corrected to normal hearing (i.e., hearing aids) and vision (i.e., eyeglasses),\n* Have no history of neurodegenerative disease (e.g., dementia), severe motor speech disorder, significant mental illness, psychiatric disorder, drug\u002Falcohol abuse, or neurological condition that could influence their cognitive, language, and memory systems\n\nExclusion Criteria:\n\n* A history of neurodegenerative disease (e.g., dementia), severe motor speech disorder, significant mental illness, psychiatric disorder, drug\u002Falcohol abuse, or neurological condition that could influence their cognitive, language, and memory systems,\n* Children under the age of 18,\n* Adults over the age of 89,\n* Uncorrected hearing and vision.","ALL","18 Years","89 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"PHASE2","The goal of this clinical trial is to compare the effectiveness of traditional Semantic Feature Analysis (SFA) treatment to a modified SFA protocol that includes Metacognitive Strategy Training (SFA+MST) for adults with acquired aphasia. The main questions it aims to answer are:\n\n* What are the comparative outcomes in picture naming accuracy and strategy use during picture naming following 2 months of traditional SFA versus SFA + MST in adults with acquired aphasia?\n* What are the comparative outcomes in percent of informative content and rate of informative content during spontaneous speech production following 2 months of traditional SFA versus SFA + MST in adults with acquired aphasia?\n\nResearchers will compare outcomes between these two treatments to see if SFA+MST yields larger effects in picture naming and spontaneous speech outcomes than traditional SFA.\n\nParticipants will complete:\n\n* 5-7 pre-treatment assessment sessions where they will be asked to name pictures, tell stories\u002Fdescribe pictures, answer questions, and complete questionnaires,\n* 3 treatment sessions of SFA \\*OR\\* SFA+MST per week for 8 weeks, for a total of 24 sessions,\n* 7 weekly probes (i.e., short, intermittent assessments throughout the treatment phase),\n* 3 post-treatment assessment sessions immediately after treatment ends, where they will complete the same assessment tasks as they did pre-treatment (e.g., naming pictures, telling stories, etc.),\n* 2 retention assessment sessions, one 30 days and the other 60 days following the final treatment session, where they will be asked to name pictures, tell stories\u002Fdescribe pictures, and describe what they learned during the study.",[27,28,29,30,31,32,33,34,35,36],"Aphasia","Aphasia Following Cerebral Infarction","Aphasia, Acquired","Aphasia, Rehabilitation","Aphasia, Anomic","Aphasia, Broca","Aphasia, Conduction","Aphasia, Expressive","Aphasia Non Fluent","Aphasia, Mixed",[27,38,39,40,41],"Anomia","Stroke","Communication","Language","RECRUITING","2026-06-23",{"date":45,"type":46},"2026-06-25","ACTUAL",{"date":48,"type":46},"2025-07-28",{"date":50,"type":21},"2027-07",{"name":52,"class":53},"Teachers College, Columbia University","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":54},"100631128","phase-3-effect-of-anodal-transcranial-direct-current-stimulation-on-naming-in-aphasic-patients-with-acute-ischemic-stroke-100631128","NCT07496645","EFFECT OF ANODAL TRANSCRANIAL DIRECT CURRENT STIMULATION ON NAMING IN APHASIC PATIENTS WITH ACUTE ISCHEMIC STROKE","Inclusion Criteria:\n\n* Aphasic patients with left middle cerebral artery territory Acute Ischemic Stroke\n* Patients between 18-65 years of age.\n* Within 5 days of onset of stroke.\n\nExclusion Criteria:\n\n* Patients with malignant Middle Cerebral Artery territory infarcts and previous clinical history of cerebral hemisphere stroke.\n* Patients with history of previous brain surgery or skull defect due to surgery e.g. craniectomy.\n* Patients with epilepsy.\n* Patients with history of significant head trauma in the last 1 month.\n* Patients with documented history of major depression prior to stroke.\n* Patients with alcohol\u002Fdrug abuse in the past 6 months.\n* Patients with prior significant cognitive impairment.\n* Pacemaker in situ, cochlear implant in situ.\n* Pregnancy.","65 Years",{"count":63,"type":21},28,[65],"PHASE3","The use of transcranial direct current stimulation (tDCS) for the management of deficits developed in stroke is a relatively new type of management option. Many of the studies performed using tDCS have focused on improvements noted in hemiplegia as compared to aphasia, which is an equally disabling outcome of strokes. The results of these studies have not been conclusive and concordant with each other.\n\nIn aphasia management, the majority of the studies have focused on chronic strokes. Since the use of tDCS is relatively new, the studies have not focused on a particular type of deficit or stroke. Very few studies have focused on the impact of solely using tDCS. Very few studies have focused on acute to subacute strokes. The results of the studies have, nevertheless, been encouraging.\n\nImprovements in aspects of language tested after a single session of tDCS are short-lived. There is an unmet need to probe the utility of repetitive tDCS on aspects of language function in patients who are aphasic due to acute stroke. There is also a paucity of data in the Indian scenario regarding the same.",[68,69,28,29],"Acute Ischemic Cerebrovascular Disease","Post Stroke Aphasia",[71,72,68,73,28],"Transcranial Direct Current Stimulation","tDCS","Post stroke aphasia","NOT_YET_RECRUITING","2026-03-21",{"date":77,"type":46},"2026-03-27",{"date":79,"type":21},"2026-03-31",{"date":81,"type":21},"2026-09-30",{"name":83,"class":84},"Dr. Ram Manohar Lohia Hospital","OTHER_GOV",{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":22,"phases":96,"briefSummary":98,"conditions":99,"keywords":103,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":121},"100614570","aphasia-physical-exercise-study-randomized-trial-100614570","NCT07281313","Aphasia Physical EXercise Study: Randomized Trial","High-intensity Exercise in Stroke Recovery: Randomized Trial","APEX","Inclusion Criteria:\n\n* Aphasia following ischemic or hemorrhagic stroke\n* Aphasia as determined by a standardized language test (Western Aphasia Battery Aphasia Quotient \\\u003C 93.8 at study intake)\n* At least 6 months from the last stroke\n* Proficient in English before the stroke\n* At least 8 years of education\n* Between the ages of 18 and 80\n* Independent with ambulation without a device (single-point cane accepted)\n* Medically stable with no contraindications to participate in regular physical exercise as determined by the patients' own primary care provider or other treating provider.\n\nExclusion Criteria:\n\n* Prior history of dementia, neurologic illness (other than stroke), or recent (last 3 years) substance abuse\n* Significant visual or hearing disabilities (e.g., neglect, uncorrected visual or hearing loss) that interfere with testing\n* Self-report uncontrolled cardiorespiratory and\u002For metabolic disorders incompatible with exercise","80 Years",{"count":95,"type":21},120,[97],"NA","The goal of this clinical trial is to evaluate the effects of a high-intensity exercise program on recovery in individuals with post-stroke aphasia. The high-intensity exercise program has been specifically designed for individuals with post-stroke aphasia and includes an interval training full-body workout, which can increase cardiovascular fitness, improve muscle strength and motor performance, and maximize cognitive and language gains. The main question this study aims to answer is:\n\n• Does participation in a high-intensity exercise program lead to changes in physical health, language, cognitive, motor recovery, psychological and\u002For psychosocial domains?\n\nParticipants will be randomly assigned to either a high-intensity exercise program (target intervention) or a low-intensity exercise program (control intervention) delivered over 12-weeks in a group setting.\n\nOutcome measures will be collected once immediately after the intervention period and once during the following 12-week maintenance period to capture short- and long-term effects of the exercise program.",[29,27,100,101,28,102],"Aphasia, Fluent","Aphasia, Non-fluent","Aphasia Following Nontraumatic Intracerebral Hemorrhage",[104,105,106,107,108,109,110,111],"aphasia","physical exercise","high intensity interval training","cognition","physical fitness","balance","stroke","language","2026-03-17",{"date":114,"type":46},"2026-03-19",{"date":116,"type":46},"2025-12-01",{"date":118,"type":21},"2030-03-01",{"name":120,"class":53},"University of California, Berkeley",4,{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":127,"acronym":128,"eligibilityCriteria":129,"healthyVolunteers":11,"sex":16,"minAge":130,"maxAge":131,"enrollmentInfo":132,"targetDuration":4,"studyType":22,"phases":134,"briefSummary":135,"conditions":136,"keywords":137,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":54},"100580856","phase-2-transcranial-magnetic-stimulation--language-therapy-to-treat-mild-aphasia-100580856","NCT06842745","Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia","Personalized Transcranial Magnetic Stimulation and Constraint Induced Language Therapy to Treat Mild Post-Stroke Aphasia","TMS","Inclusion Criteria:\n\n* Left Hemisphere stroke\n* Stroke occurred more than 6 months ago\n* Mild Aphasia (WAB AQ score \\> 85)\n* Proficient in English\n\nExclusion Criteria:\n\n* Ongoing substance or alcohol abuse\n* Other neurological disorders, beside stroke (i.e. dementia, traumatic brain injury, multiple sclerosis)\n* Active psychiatric disorders (i.e. bipolar disorder, schizophrenia)\n* Pacemaker or cardiac defibrillator\n* Diagnosis of tinnitus\n* Epilepsy, or seizure in the past 6 months","40 Years","85 Years",{"count":133,"type":21},24,[24],"The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with Speech-Language Therapy (SLT) is an effective treatment for mild aphasia in persons with chronic stroke.\n\nThe main questions this study aims to answer are:\n\n1. Can TMS combined with SLT improve conversational speech and comprehension?\n2. Can we identify specific behavioral and biological characteristics that would benefit most from the TMS and SLT treatment?\n\nResearchers will compare real TMS to sham (fake) TMS to see whether TMS can treat post-stroke mild aphasia.\n\nParticipants will:\n\n* Complete a screening and medical intake to determine eligibility\n* Undergo a MRI\n* Participate in 10 consecutive sessions (Monday-Friday) of TMS and SLT treatment\n* Complete follow-up assessments 2 and 4 months after treatment",[27,39,28,29],[104,110,138,139],"non-invasive brain stimulation","Transcranial Magnetic Stimulation","2026-03-04",{"date":142,"type":46},"2026-03-05",{"date":144,"type":46},"2025-02-11",{"date":146,"type":21},"2026-08-31",{"name":148,"class":53},"University of Pennsylvania",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":156,"sex":16,"minAge":17,"maxAge":131,"enrollmentInfo":157,"targetDuration":4,"studyType":22,"phases":158,"briefSummary":159,"conditions":160,"keywords":161,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":164,"lastUpdatePostDateStruct":165,"startDateStruct":167,"completionDateStruct":169,"leadSponsor":171,"locationsCount":54},"100523222","tacs-to-enhance-language-abilities-100523222","NCT06092814","tACS to Enhance Language Abilities","Transcranial Alternating Current Stimulation (tACS) to Enhance Language Abilities","Inclusion Criteria for Persons with Aphasia:\n\n1. Presence of aphasia\n2. Suffered a single, left hemisphere stroke\n3. Stroke ≥6 months old (chronic) at the time of enrollment\n\nInclusion Criteria for Healthy Controls:\n\n1. Right-handedness\n2. Must be able to understand the nature of the study, and give informed consent\n\nExclusion criteria for Persons with Aphasia:\n\n1. Inability to understand the nature of the study\n2. Marked naming impairment\n3. Impaired non-verbal, conceptual processing\n4. History of significant medical or neurological disorder (other than stroke)\n5. History of significant or poorly controlled psychiatric disorders\n6. Current abuse of alcohol or drugs, prescription or otherwise\n7. Nursing a child, pregnancy, or intent to become pregnant during the study\n8. Clinically significant hearing loss\n9. Contraindications to tACS\n10. Contraindications to MRI\n\nExclusion Criteria for Healthy Controls\n\n1. Diagnosis of a neurodegenerative disease or clinically significant cognitive complaint\n2. Any unrelated neurologic or physical condition that impairs communication ability\n3. History of unrelated neurological conditions including but not limited to traumatic brain injury, stroke, or small vessel disease that has resulted in a neurologic deficit\n4. Any additional neurological condition that would likely reduce the safety of study participation, including central nervous system (CNS) vasculitis, intracranial tumor, intracranial aneurysm, multiple sclerosis or arteriovenous malformations\n5. A medically unstable cardiopulmonary or metabolic disorder\n6. Terminal illness associated with survival \\\u003C12 months\n7. Major active psychiatric illness that may interfere with required study procedures or treatments as determined by the enrolling physician\n8. Current abuse of alcohol or drugs, prescription or otherwise\n9. Contraindications to tACS\n10. Contraindications to MRI",true,{"count":95,"type":21},[97],"The goal of this study is to see if transcranial alternating current stimulation (tACS) can be used to enhance language abilities in people with post-stroke aphasia. Participants will receive real and sham tACS in conjunction with various language tests. Researchers will compare the post-stroke aphasia group with aged matched controls to see if brain response to tACS differs between groups.",[39,29,27],[138,162,163],"transcranial alternating current stimulation (tACS)","EEG","2025-08-04",{"date":166,"type":46},"2025-08-08",{"date":168,"type":46},"2024-07-12",{"date":170,"type":21},"2028-08-31",{"name":148,"class":53},{"id":173,"slug":174,"hasResults":11,"nctId":175,"briefTitle":176,"officialTitle":177,"acronym":178,"eligibilityCriteria":179,"healthyVolunteers":11,"sex":16,"minAge":180,"maxAge":93,"enrollmentInfo":181,"targetDuration":4,"studyType":22,"phases":183,"briefSummary":184,"conditions":185,"keywords":187,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":193,"lastUpdatePostDateStruct":194,"startDateStruct":196,"completionDateStruct":198,"leadSponsor":200,"locationsCount":4},"100571579","vr-and-scrip-training-of-pwa-randomized-controlled-trial-100571579","NCT06722092","VR and Scrip Training of PWA, Randomized Controlled Trial","Can Immersive Virtual Reality Magnify Treatment Outcomes of Script Training on Cantonese Speakers with Chronic Aphasia: a Randomized Controlled Trial","VRSTPWA","Inclusion Criteria:\n\n1. a stroke onset more than six months, with an Aphasia Quotient (AQ) below 96.4, as evaluated by the Cantonese version of Western Aphasia Battery (CAB; Yiu, 1992),\n2. premorbid fluent Cantonese speakers,\n3. aged between 30 and 80 years,\n4. no reported progressive neurogenic disorders such as dementia or Parkinson's disease,\n5. no motor speech disorders of moderate to severe level, and\n6. normal or corrected-to-normal vision and hearing functions\n\nExclusion Criteria:\n\n1. concurrent participation in other aphasia treatment trials, and\n2. incompatibility with immersive VR exposure such as complains of nausea, headache, or other severe discomforts during trial use of a head-mounted device during screening.","30 Years",{"count":182,"type":21},105,[97],"The goal of this RCT is to investigate if computerized script training may promote functional communication and nonverbal cognitive functions of Cantonese-speaking PWA, and whether VR may further magnify the treatment outcomes.\n\nThe main research questions are:\n\n1. Can script training promote verbal functional communication of Cantonese-speaking PWA?\n2. Can script training enhance nonverbal cognitive functions of Cantonese-speaking PWA?\n3. Can VR magnify verbal and nonverbal treatment outcomes of script training of PWA?",[29,186],"Chronic Stroke",[188,189,190,191,192],"functional communication","randomized controlled trial","script training","immersive reality","aphasia intervention","2025-03-11",{"date":195,"type":46},"2025-03-13",{"date":197,"type":21},"2025-06",{"date":199,"type":21},"2028-06",{"name":201,"class":53},"The Hong Kong Polytechnic University",{"id":203,"slug":204,"hasResults":11,"nctId":205,"briefTitle":206,"officialTitle":207,"acronym":4,"eligibilityCriteria":208,"healthyVolunteers":156,"sex":16,"minAge":209,"maxAge":93,"enrollmentInfo":210,"targetDuration":4,"studyType":22,"phases":212,"briefSummary":213,"conditions":214,"keywords":4,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":218,"lastUpdatePostDateStruct":219,"startDateStruct":221,"completionDateStruct":223,"leadSponsor":225,"locationsCount":54},"100473341","enhancing-language-function-in-aphasia-100473341","NCT05443633","Enhancing Language Function in Aphasia","Enhancing Language Function in Aphasia Using Behavioral Language Intervention","Inclusion Criteria:\n\n1. Present with speech-language impairment (aphasia) caused by stroke or dementia\n2. A medical diagnosis of primary progressive aphasia (PPA) by a neurologist or physician\n3. Are native speakers of English\n4. Present with no contraindications for MRI\n5. Have adequate (normal or corrected to normal) vision and hearing\n\nExclusion Criteria:\n\n1. Individuals diagnosed with mood, anxiety, psychotic or substance abuse disorders.\n2. Individuals with highly magnetizable metallic implants, including certain dental work, may be excluded due to image quality in MRI.\n3. Individuals with other neurological disorders besides the ones of interest for the study (e.g., epilepsy, Multiple Sclerosis, Parkinson's Disease)\n4. Individuals with contraindications for MRI. This includes but is not limited to pacemakers, metallic cardiac pumps, valves, magnetic materials such as surgical clips, implanted electronic perfusion pumps, or any other condition that would preclude proximity to a strong magnetic field.\n5. Individuals suffering from clinically significant claustrophobia\n6. Severe systemic disease (e.g., renal failure)\n7. Poor overall health\n8. Individuals who are pregnant\n9. Individuals with a history of epileptic activity in the past 12 months\n10. Individuals with a personal or family history of epilepsy or other seizure disorders will not be included in the study.\n11. Individuals who have had a brain surgery in the past\n12. Individuals with implanted metallic skull plates or intracranial implants\n13. Individuals with skin lesions or skull damage\n14. Individuals who have a history of excessive use of alcohol or drugs\n15. Individuals with premorbid psychiatric disease affecting communication\n16. Individuals with severe non-linguistic cognitive disturbances impeding language therapy","21 Years",{"count":211,"type":21},30,[97],"Aphasia is an acquired impairment of language, that commonly results from damage to language areas in the brain (typically the left side of the brain). This impairment is seen in many aspects of language, including understanding, speaking, reading and writing. It is estimated that about 2 million individuals are currently living with aphasia in the United States. Further, about 200,000 Americans acquire aphasia every year (National Aphasia Association, 2020). Aphasia poses significant impact on the affected individuals and their families. Behavioral treatments that target language deficits have been shown to enhance overall communication skills and life satisfaction among individuals with aphasia. Although there is evidence that suggests that treatment is efficacious for individuals with aphasia, the extent of improvement long-term coupled with the neural patterns among those individuals are largely unknown. The current study aims to investigate the efficacy of language-based treatment and its corresponding neural patterns.",[29,215,216,217],"Language Disorders","Primary Progressive Aphasia","Stroke, Cerebrovascular","2024-12-04",{"date":220,"type":46},"2024-12-09",{"date":222,"type":46},"2022-10-30",{"date":224,"type":21},"2028-12-15",{"name":226,"class":53},"University of Arizona",{"id":228,"slug":229,"hasResults":11,"nctId":230,"briefTitle":231,"officialTitle":232,"acronym":233,"eligibilityCriteria":234,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":93,"enrollmentInfo":235,"targetDuration":4,"studyType":22,"phases":237,"briefSummary":238,"conditions":239,"keywords":241,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":248,"lastUpdatePostDateStruct":249,"startDateStruct":251,"completionDateStruct":253,"leadSponsor":255,"locationsCount":4},"100570821","anomia-therapy-and-executive-function-training-in-chronic-post-stroke-aphasia-pilot-study-of-multidimensional-effects-100570821","NCT06712225","Anomia Therapy and Executive Function Training in Chronic Post-stroke Aphasia: Pilot Study of Multidimensional Effects","Combining Anomia Therapy and Executive Function Training in Chronic Post-stroke Aphasia: a Pilot Study of Multidimensional Effects","ATAC2PILOT","Inclusion Criteria:\n\n* Adult (18-80 years old) with post-stroke aphasia (\\> 6 months post-stroke)\n* Participant or legal representative able to understand the aims of the study\n* Participant or legal representative who have signed an informed consent form\n\nExclusion Criteria:\n\n* Aphasia with severe anarthria (mutism), comprehension disorders or alexia, incompatible with the purpose of the study\n* Contraindications for MRI\n* History of head trauma, brain tumor, neurodegenerative disease, or any other neurological or psychiatric condition\n* Non-affiliation to social welfare",{"count":236,"type":21},8,[97],"The goal of this clinical trial is to measure the effects of a speech therapy protocol combining anomia therapy and executive function training on naming and discourse in people with chronic aphasia, and to study the related brain changes.\n\nThe main questions it aims to answer are:\n\n* Does the protocol improve naming skills ?\n* Do the improvements observed transfer to discourse abilities ?\n* Are there any brain changes induced by this protocol ?\n\nResearchers will compare anomia therapy alone to anomia therapy + executive function training to see if the latter works better.\n\nParticipants will:\n\n* Have a whole language assessment and a Magnetic Resonance Imaging (MRI) scan in the hospital before and after the protocol\n* Receive 18 sessions of the protocol, 3 times a week during 6 weeks, in the hospital\n* Have several naming assessments during the protocol",[29,240],"Speech Therapy",[242,243,244,245,246,247],"Post-stroke aphasia","Speech-therapy","Anomia therapy","Executive function","Discourse","Functional Magnetic Resonance Imaging","2024-11-29",{"date":250,"type":46},"2024-12-02",{"date":252,"type":21},"2025-01",{"date":254,"type":21},"2025-10",{"name":256,"class":53},"University Hospital, Montpellier",{"id":258,"slug":259,"hasResults":11,"nctId":260,"briefTitle":261,"officialTitle":261,"acronym":262,"eligibilityCriteria":263,"healthyVolunteers":156,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":264,"targetDuration":4,"studyType":22,"phases":266,"briefSummary":267,"conditions":268,"keywords":4,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":270,"lastUpdatePostDateStruct":271,"startDateStruct":273,"completionDateStruct":275,"leadSponsor":277,"locationsCount":54},"100547255","neurocognitive-mechanisms-of-sentence-production-impairment-in-aphasia-100547255","NCT06405594","Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia","sentence","Inclusion Criteria:\n\n* At least 18 years of age\n* Persons with acquired aphasia are defined as those with a language impairment following left hemisphere brain injury (most likely a stroke).\n* Neurotypical adults need to be either young (ages 18-30 years) or older (\\> 60 years)\n* Native (or primary) speakers of English\n\nExclusion Criteria:\n\n* Prior neurological or psychiatric diagnoses or developmental disabilities before the onset of aphasia\n* do not speak English fluently",{"count":265,"type":21},350,[97],"The proposed research is relevant to public health because stroke is a leading cause of long-term disability among older adults and communication impairments resulting from stroke have a significant negative impact on quality of life. By seeking to better understand post-stroke aphasia, this project lays the groundwork for development of new interventions, and aligns with NIDCD's priority areas 1 (understanding normal function), 2 (understanding diseases), and 3 (improving diagnosis, treatment, and prevention).",[29,39,269],"Healthy Aging","2024-08-28",{"date":272,"type":46},"2024-09-03",{"date":274,"type":46},"2024-08-01",{"date":276,"type":21},"2029-06",{"name":278,"class":53},"University of Maryland, College Park",{"id":280,"slug":281,"hasResults":11,"nctId":282,"briefTitle":283,"officialTitle":284,"acronym":285,"eligibilityCriteria":286,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":287,"targetDuration":4,"studyType":22,"phases":288,"briefSummary":289,"conditions":290,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":291,"lastUpdatePostDateStruct":292,"startDateStruct":294,"completionDateStruct":296,"leadSponsor":298,"locationsCount":4},"100483234","clinic-and-neurophysiology-of-aphasia-treatment-100483234","NCT05572385","Clinic and Neurophysiology of Aphasia Treatment","Clinical and Neurophysiological Features of Neurorehabilitation Effects in Cerebrovascular Aphasia","AphasRehab","Inclusion Criteria:\n\n* patients with a cerebrovascular event\n\nExclusion Criteria:\n\n* premorbid brain disorder",{"count":20,"type":21},[97],"In the planned study, clinical and electrophysiological features of aphasia recovery in stroke patients are investigated.",[29],"2022-10-06",{"date":293,"type":46},"2022-10-07",{"date":295,"type":21},"2023-07-01",{"date":297,"type":21},"2026-12-31",{"name":299,"class":53},"Klinik Bavaria"]