[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"aphasia-following-nontraumatic-intracerebral-hemorrhage\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:aphasia-following-nontraumatic-intracerebral-hemorrhage":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":34,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":55},"100614570","aphasia-physical-exercise-study-randomized-trial-100614570",false,"NCT07281313","Aphasia Physical EXercise Study: Randomized Trial","High-intensity Exercise in Stroke Recovery: Randomized Trial","APEX","Inclusion Criteria:\n\n* Aphasia following ischemic or hemorrhagic stroke\n* Aphasia as determined by a standardized language test (Western Aphasia Battery Aphasia Quotient \\\u003C 93.8 at study intake)\n* At least 6 months from the last stroke\n* Proficient in English before the stroke\n* At least 8 years of education\n* Between the ages of 18 and 80\n* Independent with ambulation without a device (single-point cane accepted)\n* Medically stable with no contraindications to participate in regular physical exercise as determined by the patients' own primary care provider or other treating provider.\n\nExclusion Criteria:\n\n* Prior history of dementia, neurologic illness (other than stroke), or recent (last 3 years) substance abuse\n* Significant visual or hearing disabilities (e.g., neglect, uncorrected visual or hearing loss) that interfere with testing\n* Self-report uncontrolled cardiorespiratory and\u002For metabolic disorders incompatible with exercise","ALL","18 Years","80 Years",{"count":21,"type":22},120,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to evaluate the effects of a high-intensity exercise program on recovery in individuals with post-stroke aphasia. The high-intensity exercise program has been specifically designed for individuals with post-stroke aphasia and includes an interval training full-body workout, which can increase cardiovascular fitness, improve muscle strength and motor performance, and maximize cognitive and language gains. The main question this study aims to answer is:\n\n• Does participation in a high-intensity exercise program lead to changes in physical health, language, cognitive, motor recovery, psychological and\u002For psychosocial domains?\n\nParticipants will be randomly assigned to either a high-intensity exercise program (target intervention) or a low-intensity exercise program (control intervention) delivered over 12-weeks in a group setting.\n\nOutcome measures will be collected once immediately after the intervention period and once during the following 12-week maintenance period to capture short- and long-term effects of the exercise program.",[28,29,30,31,32,33],"Aphasia, Acquired","Aphasia","Aphasia, Fluent","Aphasia, Non-fluent","Aphasia Following Cerebral Infarction","Aphasia Following Nontraumatic Intracerebral Hemorrhage",[35,36,37,38,39,40,41,42],"aphasia","physical exercise","high intensity interval training","cognition","physical fitness","balance","stroke","language","RECRUITING","2026-03-17",{"date":46,"type":47},"2026-03-19","ACTUAL",{"date":49,"type":47},"2025-12-01",{"date":51,"type":22},"2030-03-01",{"name":53,"class":54},"University of California, Berkeley","OTHER",4]