[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"areata-alopecia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:areata-alopecia":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100494824","phase-3-a-study-of-baricitinib-ly3009104-in-children-from-6-years-to-less-than-18-years-of-age-with-alopecia-areata-100494824",false,"NCT05723198","A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata","A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of Baricitinib in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata","BRAVE-AA-PEDS","Inclusion Criteria:\n\n* Enrollment will be fully sequential by age group, with adolescents (12 to less than 18 years old) enrolling before children (6 to less than 12 years old).\n* Have severe areata alopecia (AA) for at least 1 year\n* Diagnosis for at least 1 year\n* Current AA episode of at least 6 months' duration\n* SALT score ≥50% at screening and baseline\n* History of trial and failure with at least 1 available treatment (topical or other) for AA\n* History of psychological counseling related to AA\n* Current episode of severe AA of less than 8 years.\n\n  * Note: Participants who have severe AA for ≥8 years may be enrolled if episodes of regrowth, spontaneous or under treatment, have been observed on the affected areas over the past 8 years.\n\nExclusion Criteria:\n\n* Primarily \"diffuse\" type of AA (characterized by diffuse hair shedding).\n* Are currently experiencing other forms of alopecia including, but not limited to trichotillomania, telogen effluvium, chemotherapy-induced hair loss, or any other concomitant conditions (for example, tinea capitis, psoriasis, lupus erythematosus, or secondary syphilis) that would interfere with evaluations of the effect of study medication on AA.\n* Are largely or wholly incapacitated permitting little or no self-care, such as being bedridden\n* Have uncontrolled arterial hypertension\n* Have had major surgery within 8 weeks prior to screening or will require major surgery during the study\n* Have a history or presence of cardiovascular, respiratory, hepatic, gastrointestinal, endocrine, hematological, neurological, or neuropsychiatric disorders or any other serious and\u002For unstable illness that, in the opinion of the investigator, could constitute an unacceptable risk when taking IP or interfere with the interpretation of data.\n* Have a positive test for hepatitis B virus (HBV) infection\n* Have hepatitis C virus (HCV) infection (positive for anti hepatitis C antibody with confirmed presence of HCV ribonucleic acid \\[RNA\\]).\n* Have evidence of human immunodeficiency virus (HIV) infection and\u002For positive HIV antibodies.","ALL","6 Years","17 Years",{"count":21,"type":22},595,"ESTIMATED","INTERVENTIONAL",[25],"PHASE3","The main purpose of this study is to determine the efficacy and safety of baricitinib for the treatment of severe or very severe alopecia areata (hair loss) in children from 6 years to less than 18 years of age.\n\nThe study is divided into 4 periods, a 5-week Screening period, a 36-week Double-Blind Treatment Period, an approximately 2-year Long-term Extension (LTE) Period, and a 4-week Post-treatment Follow-up period. Some individuals may be eligible to receive treatment after completing the LTE, for a maximum of 180 weeks.",[28,29,30,31,32,33],"Areata Alopecia","Alopecia","Hypotrichosis","Hair Diseases","Skin Diseases","Pathological Conditions, Anatomical","RECRUITING","2026-05-18",{"date":37,"type":38},"2026-05-20","ACTUAL",{"date":40,"type":38},"2023-02-27",{"date":42,"type":22},"2033-09",{"name":44,"class":45},"Eli Lilly and Company","INDUSTRY",127,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":74},"100577709","evaluation-of-stigma-toward-patients-with-alopecia-areata-atopic-dermatitis-vitiligo-and-psoriasis-100577709","NCT06801821","Evaluation of Stigma Toward Patients With Alopecia Areata, Atopic Dermatitis, Vitiligo, and Psoriasis","STIGMADERM","Inclusion Criteria:\n\n* -Patients aged\\>18 years, both sexes;\n* Signature of written informed consent;\n\nExclusion Criteria:\n\n* Patients diagnosed with psoriasis, atopic dermatitis, vitiligo or alopecia areata.\n* Patients with first-degree relatives with psoriasis, atopic dermatitis, vitiligo or alopecia areata\n* Those who for professional or personal reasons have direct knowledge of the diseases in question.",true,"18 Years",{"count":57,"type":22},400,"OBSERVATIONAL","Primary objective:\n\nThe primary objective is to evaluate in the general population the difference between emotional reactions associated with facial involvement by four major dermatologic diseases: psoriasis, atopic dermatitis, vitiligo, and alopecia areata.\n\n* Compare the social distance and stereotyping by the general population toward individuals with facial involvement by: psoriasis, atopic dermatitis, vitiligo, and alopecia areata.\n* Evaluate demographic factors that describe a greater tendency toward stigmatization.",[61,62,63,28],"Psoriasis (PsO)","Vitiligo Vulgaris","Atopic Dermatitis","2025-08-25",{"date":66,"type":38},"2025-08-26",{"date":68,"type":38},"2025-02-01",{"date":70,"type":22},"2026-03-01",{"name":72,"class":73},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","OTHER",1]