[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"arthroplasty-complications\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:arthroplasty-complications":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,15,0,[8,49,76,104,130,163,187,216,247,273,300,326,360,385,408],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100636636","the-effectiveness-of-high-intensity-laser-therapy-on-post-surgical-rehabilitation-after-total-knee-arthroplasty-100636636",false,"NCT07568262","The Effectiveness of High-intensity Laser Therapy on Post-surgical Rehabilitation After Total Knee Arthroplasty","The Effectiveness of High-intensity Laser Therapy on Post-surgical Rehabilitation: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients undergoing primary unilateral total knee arthroplasty for primary knee osteoarthritis\n* Age between 50 and 80 years\n* Pain intensity greater than 30\u002F100 on the Visual Analog Scale (VAS)\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Psychiatric disorders\n* Cognitive impairments\n* Previous major trauma or surgery involving the affected knee\n* Rheumatic diseases or fibromyalgia\n* Vascular diseases\n* Neoplastic diseases\n* Infectious diseases\n* Neurological disorders\n* Hemophilia or bleeding disorders\n* Current anticoagulant therapy\n* Presence of a pacemaker\n* History of epileptic seizures\n* Known hypersensitivity or contraindication to laser therapy\n* Suspected conditions in which tissue heating is contraindicated\n* Use of photosensitizing medications or known photosensitivity\n* Skin lesions or abrasions at the treatment site\n* Tattoos in the treatment area\n* Intra-articular steroid injections in the target knee within the previous 2-3 weeks\n* Recent significant trauma or injury\n* Use of anti-inflammatory or analgesic medications or other pain-relieving treatments (if not controlled or standardized)\n* Pregnancy or breastfeeding\n* Positive status for human immunodeficiency virus","ALL","50 Years","80 Years",{"count":20,"type":21},46,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized controlled trial aims to evaluate the effectiveness of high-intensity laser therapy (HILT) as an adjunct to conventional rehabilitation in patients undergoing total knee arthroplasty (TKA).\n\nPersistent pain and functional limitations are common after TKA despite standard rehabilitation, highlighting the need for adjunctive therapies to optimize postoperative recovery. High-intensity laser therapy has been proposed as a non-invasive intervention with potential analgesic and anti-inflammatory effects; however, its effectiveness in this population remains unclear.\n\nParticipants will be randomly allocated to one of two groups: an experimental group receiving HILT in addition to conventional physiotherapy and a control group receiving sham laser therapy combined with the same rehabilitation program. Both groups will undergo standardized rehabilitation sessions lasting 60 minutes, including 15 minutes of active or sham laser therapy and 45 minutes of conventional physiotherapy.\n\nThe primary outcome is postoperative pain. Secondary outcomes include joint swelling, range of motion, muscle strength, physical function, and quality of life.\n\nAssessments will be conducted at baseline (preoperative), at 1 month after surgery (prior to the start of rehabilitation), during the rehabilitation program (after the fourth, seventh, and tenth physiotherapy sessions), and at 4 months postoperatively (follow-up).\n\nA total of 46 participants (23 per group) will be enrolled in the study.",[27,28],"Arthroplasty Complications","Pain, Postoperative",[30,31,32,33,34,35],"Total knee arthroplasty","High-level laser therapy","Laser therapy","Post-operative pain","Rehabilitation","Physical therapy","NOT_YET_RECRUITING","2026-04-28",{"date":39,"type":40},"2026-05-05","ACTUAL",{"date":42,"type":21},"2026-09",{"date":44,"type":21},"2028-09",{"name":46,"class":47},"Istituto Ortopedico Rizzoli","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":61,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":48},"100559392","are-elastic-restraints-still-necessary-in-improved-rehabilitation-programs-after-hip-and-knee-prosthetic-surgery-100559392","NCT06563531","Are Elastic Restraints Still Necessary in Improved Rehabilitation Programs After Hip and Knee Prosthetic Surgery?","Inclusion Criteria:\n\n* first line and non-traumatic total hip or knee arthroplasty\n* Patient included in an Enhanced Rehabilitation after Surgery (ERS) or \"fast-track\" protocol, or scheduled as an outpatient.\n\nExclusion Criteria:\n\n* Patient requiring long-term anticoagulation for pre-existing co-morbidity\n* Patients with coagulation disorders (hypercoagulability)\n* Patient undergoing thrombogenic pharmacological treatment\n* History of obliterative arteriopathy of the lower limbs\n* Arterial disease\n* Obesity\n* Heart failure\n* Chronic bronchopneumopathy\n* Lymphedema\n* Chronic inflammatory disease\n* Permanent wearing of elastic restraints\n* Proximal or distal arterial bypass surgery\n* Creatinine clearance \\\u003C 15 ml\u002Fmin\n* Inability to give consent\n* Revision surgery for hip or knee prosthesis\n* Metastatic cancer\n* Life expectancy less than 3 months\n* Allergy to socks or compression stockings\n* Patients presenting one or more exclusion criteria for the fast-track protocol (severe or poorly-balanced associated conditions such as diabetes or immunodepression, inability to contact the doctor or hospital department if necessary, pre-operative ASA score greater than or equal to 4).\n* Adults under guardianship or curatorship\n* Vulnerable persons in accordance with article L1121-6 of the CSP (French Public Health Code)","18 Years",{"count":57,"type":21},1274,[24],"Venous thrombosis and pulmonary embolism are considered serious and potentially preventable complications of hip and knee replacement surgery. The risks of thrombosis must be weighed against the risks associated with preventive measures, both mechanical and pharmacological. Modern medicine is now questioning the use of elastic restraints in surgery. Several studies have investigated the benefits of using restraints to prevent thromboembolic events. These studies have shown no additional benefit from the use of compression stockings in thromboembolism prevention. To the best of our knowledge, no orthopedic study has investigated the non-inferiority of pharmacological treatment compared with elastic compression devices, specifically in knee and hip surgery. The aim of this multicenter, prospective, randomized study is to investigate whether pharmacological prophylaxis alone is non-inferior to pharmacological and mechanical prophylaxis (using restraints) of peripheral venous thrombosis or pulmonary embolism up to 90 days after prosthetic surgery.",[27],[62,63,64,65],"hip replacement surgery","knee replacement surgery","thromboprophylaxis","elastic compression","RECRUITING","2026-03-31",{"date":69,"type":40},"2026-04-06",{"date":71,"type":40},"2024-11-15",{"date":73,"type":21},"2027-07-15",{"name":75,"class":47},"Clinique Pasteur Lanroze",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":92,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":48},"100538631","real-component-vs-all-cement-articulating-spacers-for-periprosthetic-knee-infection-100538631","NCT06293352","Real-component vs All-cement Articulating Spacers for Periprosthetic Knee Infection","Durable, Real-component Antibiotic Spacers vs All-cement Articulating Spacers for the Treatment of Periprosthetic Knee Infection","Inclusion Criteria:\n\n* Patients diagnosed with a chronic periprosthetic joint infection after a primary total knee arthroplasty with plan for explant and placement of an antibiotic spacer\n* PJI defined according to Musculoskeletal Infection Society (MSIS) 2018 Consensus Criteria\n\nExclusion Criteria:\n\n* Patients who are unable to consent\n* Infection at site of revision TKA\n* Soft tissue envelope compromise\n* Allergies to study materials (cement, vancomycin, tobramycin)\n* Incompetent extensor mechanism\n* Extensive bone loss\n\nRandomization-specific exclusion criteria\n\n* Extensive soft tissue defect\n* Extensor mechanism compromise",{"count":84,"type":21},153,[24],"In the US, if an infection in an artificial knee joint doesn't heal with antibiotics alone, the standard treatment is a two-stage revision of the artificial knee. In the first stage, the surgeon will remove the artificial knee and clean out the area around the knee. They will then place an antibiotic spacer. An antibiotic spacer is a type of artificial joint that will release antibiotics into the knee space continuously over time. The spacer allows only very basic function of the knee. The patient may need to use crutches or a walker while the antibiotic spacer is in place. After surgery to place the antibiotic spacer, the surgeon may prescribe a course of antibiotics as well. Because the antibiotic spacer is not as durable as a regular artificial joint, after the infection is gone, another surgery is required to take the spacer out and put a new artificial knee joint in.\n\nThere is another way for artificial joint infections to be treated. This is a one-stage revision. In this treatment, the surgeon will remove the artificial knee and clean out the area around the knee. Then the surgeon will place a new artificial knee in using a special kind of cement that contains antibiotics. The cement will release antibiotics into the knee space continuously over time (the surgeon may prescribe a course of antibiotics as well). The new artificial joint with antibiotic cement will function almost the same as the original artificial knee. This means that while the infection is healing the patient will be able to do most of the regular daily activities. However, the antibiotic cement is not as durable as what is normally used to implant an artificial knee. The artificial knee with the antibiotic cement may need to be replaced with a regular artificial knee. When replacement will need to be done is dependent on patient weight, bone strength and activity level, among other things. When it is time to replace the antibiotic cement artificial knee, the patient will have another surgery where the surgeon will take the antibiotic cement artificial knee and put a new artificial knee joint in.\n\nInvestigators know that both the one- and two-stage revision work equally well to heal the infection, but investigators don't know which patients prefer or which provides better function after many years. This study will randomly assign patients to receive either a one-stage or two-stage revision and then follow them for 5 years to ask them about pain, function, and satisfaction.",[88,89,27,90,91],"Prosthetic-joint Infection","Knee Infection","Joint Infection","Arthroplasty, Replacement, Knee",[93,94],"randomized trial","patient-reported outcomes","2026-03-20",{"date":97,"type":40},"2026-03-24",{"date":99,"type":40},"2024-08-08",{"date":101,"type":21},"2026-12",{"name":103,"class":47},"Northwestern University",{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":110,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":112,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":114,"conditions":115,"keywords":118,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":48},"100556635","innovative-technologies-for-salvage-procedures-of-failed-treatments-of-osteoarthritis-biomimetics-solutions-custompn-100556635","NCT06527664","Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions (CustomPN)","Innovative Technologies for Cost-Effective Healthcare Delivery for Salvage Procedures of Failed Treatments of Osteoarthritis: Specific Biomimetics Solutions to Reduce a Growing Problem With a High Social and Economic Impact.(CustomPN)","CustomPN","Inclusion Criteria:\n\n* need of custom-made acetabular implant on the basis of CT and X-ray evaluation ()\n* pre-operative CT scan\n* adults patients (minimum age: 18 years)\n* complete medical charts\n* patients' availability\n\nExclusion Criteria:\n\n* oncological reasons for revision\n* other types of revision implant (non custom)\n* inadequate medical chart\n* lack of pre-operative CT scan",{"count":5,"type":21},"OBSERVATIONAL","In this prospective multicenter study, a population of adult individuals consecutively treated for revision hips, requiring a custom-made acetabular implant for non-oncological reasons, will be included. The custom-made implant is a personalized implant produced using additive manufacturing, based on the pre-operative CT scan that details the bone damage. Patients eligible for this implant are those with severe acetabular bone damage Paprosky 3 (loss of the superolateral part and one of the two ventro-caudal walls).\n\nPreoperatively, the patient will undergo a clinical evaluation. Data will be collected on the patient's general health status with the Charlson score, the reason for revision, number of revisions, type of implant in place, and the time elapsed between the failed implant and the revision in question. The bone deficit will be studied through CT measurements according to qualitative and quantitative scales. During the surgery, information on intraoperative complications will be collected. In the postoperative period, perioperative complications will be collected according to the Clavien Dindo classification. The clinical radiographic evaluations will be carried out during outpatient follow-up visits at 1, 3, 12, 24, and 36 months after revision. They include the Harris Hip Score clinical score, the EQ-5D PROM, and the patient's satisfaction level (qualitative assessment in 4 grades: unsatisfied, slightly satisfied, moderately satisfied, fully satisfied). The positional parameters of the implant will be evaluated, as compared to the immediate post-operative X-ray: acetabular abduction, acetabular anteversion, center of rotation height, center of rotation medialization, and inclination of the custom-made component. From 12 months onwards, the osteointegration characteristics of the component will be assessed: presence of radial trabeculae at the interface, superolateral and inferior reinforcements, stress shielding, absence of radiolucent lines. Re-revision rates will be determined using the Kaplan-Meier method. The reasons for re-revision will be noted.",[116,117,27],"Bone Loss","Hip Prosthesis Infection",[119,120,121],"revision hip arthroplasty","custom-made implant","additive manufacturing","2026-02-19",{"date":124,"type":40},"2026-02-23",{"date":126,"type":40},"2024-10-01",{"date":128,"type":21},"2026-09-30",{"name":46,"class":47},{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":4,"eligibilityCriteria":136,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":137,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":139,"conditions":140,"keywords":144,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":162},"100425529","persona-revision-knee-system-outcomes-100425529","NCT04821154","Persona Revision Knee System Outcomes","Clinical Investigation to Demonstrate Performance, Safety and Clinical Benefits of the Persona Revision Knee System","Inclusion Criteria:\n\n1. Male or female of at least 18 years of age at the time of screening.\n2. Signed an institutional review board approved informed consent.\n3. Willingness and ability to comply with the study procedures and visit schedules and ability to understand and follow oral and written post-operative care instructions.\n4. Previous medical diagnosis\u002F history of at least one of the following conditions requiring treatment using the Persona Revision Knee System within a pre-specified study variant configuration (cohort), in accordance with the instructions for use (IFU):\n\n   1. Rheumatoid arthritis, osteoarthritis, traumatic arthritis or polyarthritis\n   2. Collagen disorders, and\u002For avascular necrosis of the femoral condyle\n   3. Post-traumatic loss of joint configuration, particularly when there is patellofemoral erosion, dysfunction or prior patellectomy\n   4. Moderate valgus, varus, or flexion deformities\n   5. The salvage of previously failed surgical attempts or for a knee in which satisfactory stability in flexion cannot be obtained at the time of surgery\n5. A pre-operative Knee Society Knee Score (objective assessment) ≤ 80.\n\nExclusion Criteria:\n\n1\\) Presence of clinically observed active or suspected latent infection in the affected joint at the time of procedure.\n\n3\\) Presence of of local\u002Fsystemic\u002Fdistant focal infection that may affect or hematogenously spread to the prosthetic joint.\n\n4\\) Skeletal immaturity or insufficient bone stock on femoral or tibial surfaces which cannot provide adequate support and\u002For fixation to the prosthesis.\n\n5\\) Diagnosed with neuropathic arthropathy, osteoporosis, or any loss of musculature or neuromuscular disease that compromises the affected limb.\n\n6\\) Presence of a stable, painless arthrodesis in a satisfactory functional position in the affected joint.\n\n7\\) Severe instability of the affected joint secondary to the absence of collateral ligament integrity.\n\n8\\) Diagnosis of rheumatoid arthritis in conjunction with any of the following at the time of screening:\n\n1. An ulcer of the skin\n2. History of recurrent breakdown of the skin\n3. Use of steroids\n\n   9\\) Patient requires simultaneous bilateral knee surgery for treatment of diagnosed condition.\n\n   10\\) Pregnant or women planning to become pregnant during the time they will be participating in the study.\n\n   11\\) Any documented clinically significant degree of cognitive impairment or other condition, finding, or psychiatric illness at screening which, in the opinion of the Investigator, could compromise patient safety or interfere with the assessment of the safety and treatment effects of the study procedure.\n\n   12\\) Any patient who is institutionalized, or with a known drug or alcohol dependence currently or within the last year.",{"count":138,"type":21},380,"The study will evaluate the performance, clinical benefits and safety of the Persona Revision Knee System in patients who have received primary or revision total knee arthroplasty (TKA) treatment. This will be done using a multicenter, single-arm, consecutive series, retrospective cohort study with prospective follow-up.",[27,141,142,143],"Infection","Knee Disease","Knee Osteoarthritis",[145,146,147,148,149,150,151],"Revision","Total Knee","Medical Device","Safety","Performance","Primary","Clinical Benefits","2025-10-22",{"date":154,"type":40},"2025-10-24",{"date":156,"type":40},"2021-06-14",{"date":158,"type":21},"2027-12-31",{"name":160,"class":161},"Zimmer Biomet","INDUSTRY",16,{"id":164,"slug":165,"hasResults":11,"nctId":166,"briefTitle":167,"officialTitle":168,"acronym":4,"eligibilityCriteria":169,"healthyVolunteers":170,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":171,"targetDuration":4,"studyType":22,"phases":173,"briefSummary":174,"conditions":175,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":178,"lastUpdatePostDateStruct":179,"startDateStruct":181,"completionDateStruct":183,"leadSponsor":185,"locationsCount":48},"100504187","surgeon-initiated-bone-health-referral-pathway-in-patients-undergoing-lower-extremity-arthroplasty-100504187","NCT05845021","Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty","The Impact of a Surgeon-Initiated Bone Health Referral Pathway on Implant-Related Complications in Patients With Osteoporosis Undergoing Lower Extremity Arthroplasty","Inclusion Criteria:\n\n* \\>50\n* DEXA-confirmed diagnosis of osteoporosis\n\nExclusion Criteria:\n\n* Prior diagnosis of osteoporosis\n* Prior treatment for osteoporosis",true,{"count":172,"type":21},2000,[24],"The goal of this clinical trial is to observe the impact of a surgeon-driven bone health referral pathway following lower extremity arthroplasty. The main question this study aims to answer is:\n\n1\\) What is impact of a surgeon-driven bone health referral pathway on implant-related complications and fragility fractures when compared to standard of care primary care provider referral.\n\nResearchers will compare the endocrinology referral pathway and standard of care to see if there is a difference in treatment rates, fragility fractures, and implant-related complications following lower extremity arthroplasty.",[176,27,177],"Osteoporosis","Fragility Fracture","2025-10-10",{"date":180,"type":40},"2025-10-14",{"date":182,"type":40},"2023-09-27",{"date":184,"type":21},"2028-07",{"name":186,"class":47},"Johns Hopkins University",{"id":188,"slug":189,"hasResults":11,"nctId":190,"briefTitle":191,"officialTitle":192,"acronym":4,"eligibilityCriteria":193,"healthyVolunteers":170,"sex":16,"minAge":55,"maxAge":194,"enrollmentInfo":195,"targetDuration":4,"studyType":22,"phases":197,"briefSummary":198,"conditions":199,"keywords":203,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":207,"lastUpdatePostDateStruct":208,"startDateStruct":210,"completionDateStruct":212,"leadSponsor":214,"locationsCount":48},"100590577","l-investigation-of-robotic-assisted-tka-ra-tka-with-skywalker-and-evolution-medial-pivot-knee-emp-knee-100590577","NCT06969222","l Investigation of Robotic-assisted TKA (RA-TKA) With Skywalker and Evolution Medial Pivot Knee (eMP Knee)","A Prospective Clinical Investigation of Robotic-assisted TKA (RA-TKA) With Skywalker and Evolution Medial Pivot Knee (eMP Knee)","Inclusion Criteria:\n\n1. \\>= 18 Years Male or Female\n2. With noninflammatory degenerative joint disease, inflammatory joint disease, functional deformity\n3. The subject has signed the Ethical Board approved Informed Consent Form specific to this study prior to enrollment\n4. Must be independent, ambulatory, and can comply with all post-operative evaluations and visits.\n\nExclusion Criteria:\n\n1. Subjects with poor compliance, unable to complete the trial according to the requirements or for other reasons or considered not to be suitable for inclusion by investigators.\n2. Concurrent participation in any other total hip or knee replacement studies.","95 Years",{"count":196,"type":21},122,[24],"This is a prospective trial that attempts to develop evidence on the safety and performance of RA-TKA (Robotic-assisted total knee arthroplasty) with Skywalker and eMP (Evolution Medial Pivot) knee. Moreover to evaluate performance of eMP patients with Skywalker (in comparison to eMP with conventional instrumentations and non-MP TKAs)",[200,27,201,202],"Knee Arthropathy","Robotic Assisted Arthroplasty","TKA Outcomes",[204,205,206],"knee arthroplasty","Skywalker robotic System","evolution medial pivot implant","2025-05-08",{"date":209,"type":40},"2025-05-13",{"date":211,"type":40},"2023-09-05",{"date":213,"type":21},"2026-12-31",{"name":215,"class":47},"Orthopaedic Department of General University Hospital of Laria",{"id":217,"slug":218,"hasResults":11,"nctId":219,"briefTitle":220,"officialTitle":221,"acronym":222,"eligibilityCriteria":223,"healthyVolunteers":11,"sex":16,"minAge":224,"maxAge":18,"enrollmentInfo":225,"targetDuration":4,"studyType":22,"phases":227,"briefSummary":228,"conditions":229,"keywords":233,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":238,"lastUpdatePostDateStruct":239,"startDateStruct":241,"completionDateStruct":243,"leadSponsor":245,"locationsCount":48},"100455153","achilles-tendon-for-the-treatment-of-gluteus-medius-insufficiency-100455153","NCT05206838","Achilles Tendon for the Treatment of Gluteus Medius Insufficiency","Achilles Tendon Homograft for the Treatment of Gluteus Medius Insufficiency After Hip Replacement","HLS","Inclusion Criteria:\n\n* Persisting limping with positive Trendelenburg's sign for at least 12 months after total hip arthroplasty\n* Rupture\u002Favulsion of the gluteus medius tendon verified with ultrasound or MRI\n* Leg length discrepancy of less than 1 cm\n* Femoral offset discrepancy of less than 25%\n\nExclusion Criteria:\n\n* Neuromuscular disorders","40 Years",{"count":226,"type":21},44,[24],"Residual limping after total hip arthroplasty is a serious complication that lacks effective treatment. The purpose of this study is to evaluate a surgical treatment for residual limping and compare its results with non-surgical treatment. Our hypothesis is that surgical treatment followed by physiotherapy increases hip function and reduces limping compared with non-surgical treatment with physiotherapy alone.",[27,230,231,232],"Muscle Weakness","Muscle Atrophy","Muscle Tear",[234,235,236,237],"Gluteus medius","Limp","Abductor","Trendelenburg","2025-04-05",{"date":240,"type":40},"2025-04-08",{"date":242,"type":40},"2022-06-29",{"date":244,"type":21},"2028-12",{"name":246,"class":47},"Sahlgrenska University Hospital",{"id":248,"slug":249,"hasResults":11,"nctId":250,"briefTitle":251,"officialTitle":252,"acronym":253,"eligibilityCriteria":254,"healthyVolunteers":11,"sex":16,"minAge":224,"maxAge":18,"enrollmentInfo":255,"targetDuration":4,"studyType":22,"phases":257,"briefSummary":258,"conditions":259,"keywords":262,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":238,"lastUpdatePostDateStruct":267,"startDateStruct":269,"completionDateStruct":271,"leadSponsor":272,"locationsCount":48},"100455907","the-role-of-surgical-approach-on-residual-limping-after-total-hip-arthroplasty-100455907","NCT05216666","The Role of Surgical Approach on Residual Limping After Total Hip Arthroplasty","Abductor Insufficiency After Total Hip Arthroplasty; Risk Factors and Diagnosis","HSS","Inclusion Criteria:\n\n* Primary unilateral osteoarthritis of the hip scheduled for total hip arthroplasty.\n* Ability to understand and write swedish.\n\nExclusion Criteria:\n\n* Impaired funktion of the contralateral hip or knees causing limping.\n* Neuromuscular diseases\n* Postoperative leg length discrepancy excceding 1 cm\n* Postoperative discrepancy in femoral offset exceeding 25% of the femoral offset of the contralateral hip.",{"count":256,"type":21},580,[24],"Residual limping after total hip arthroplasty is empirically associated with the use of lateral approach but has been reported in litterature even with the use of posterior approach. The purpose of this clinical trial is to compare the risk of residual limping one year after total hip arthropasty between lateral and posterior approach.",[260,230,231,261,27],"Hip Osteoarthritis","Muscle Injury",[263,264,265,237,266],"abductor","approach","limp","gluteus medius",{"date":268,"type":40},"2025-04-09",{"date":270,"type":40},"2022-05-11",{"date":244,"type":21},{"name":246,"class":47},{"id":274,"slug":275,"hasResults":11,"nctId":276,"briefTitle":277,"officialTitle":278,"acronym":279,"eligibilityCriteria":280,"healthyVolunteers":170,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":281,"targetDuration":283,"studyType":113,"phases":4,"briefSummary":284,"conditions":285,"keywords":289,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":291,"lastUpdatePostDateStruct":292,"startDateStruct":294,"completionDateStruct":296,"leadSponsor":298,"locationsCount":48},"100584136","ototoxicity-in-patients-with-mom-hip-bearings-100584136","NCT06885411","Ototoxicity in Patients With MoM Hip Bearings","Ototixicity in Patients With a Metal-on-Metal Hip Arthroplasty","GODMOTHER","Inclusion Criteria:\n\n* all MoM patients from the different clinics\n* revision MoM\n* willing to participate\n* speak\u002Fwrite the Dutch language\n\nExclusion Criteria:\n\n* Not willing to participate\n* previous ENT surgery or ENT pathology",{"count":282,"type":21},200,"1 Day","The goal of this observational study is to learn about ototoxicity in patients with a MoM hip arthroplasty. The main question it aims to answer is:\n\n• What is the prevalence of hearing loss in patients with high and low plasma metal concentrations.",[286,287,288,27],"Ototoxic Hearing Loss","Cobalt Poisoning","Chromium Causing Toxic Effect",[290],"Metal-on-Metal implant; Cobalt; Chromium; Hip arthroplasty; auditory system; Otoxicity","2025-03-17",{"date":293,"type":40},"2025-03-20",{"date":295,"type":40},"2023-02-01",{"date":297,"type":21},"2025-12-01",{"name":299,"class":47},"Reinier Haga Orthopedisch Centrum",{"id":301,"slug":302,"hasResults":11,"nctId":303,"briefTitle":304,"officialTitle":305,"acronym":4,"eligibilityCriteria":306,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":307,"targetDuration":4,"studyType":22,"phases":309,"briefSummary":310,"conditions":311,"keywords":313,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":317,"lastUpdatePostDateStruct":318,"startDateStruct":320,"completionDateStruct":322,"leadSponsor":324,"locationsCount":48},"100556308","effect-of-game-activity-and-stress-ball-on-anxiety-and-vital-signs-100556308","NCT06523413","Effect of Game Activity and Stress Ball on Anxiety and Vital Signs","Effectiveness of Game Activity and Stress Ball on Preoperative Anxiety and Vital Signs","Inclusion Criteria:\n\nBeing over 18 years old Undergoing total knee arthroplasty Having passed the Mini-Cog test Ability to understand, read, and write Turkish No hearing or speech problems Having a person accompanying the patient\n\nExclusion Criteria:\n\nNot wanting to participate in the research Unstable general condition Sudden change in vital signs Having a psychological disorder and using antidepressant medication Having any psychiatric or cognitive\u002Fmental disease (e.g., dementia) Use of psychiatric medication for any reason",{"count":308,"type":21},75,[24],"This randomized controlled trial aims to determine the effect of game activity and stress ball use on preoperative anxiety and vital signs in patients undergoing total knee arthroplasty. The primary purpose of the study is to evaluate the effect of these methods (game activity, stress ball use) on patients' anxiety and vital signs. The research involves three groups: one group will engage in a game activity, another group will use a stress ball, and the control group will receive no intervention. Patients over 18 years of age who pass the Mini-Cog test, demonstrate cognitive competence and meet other sampling criteria will be included in the study. Data will be collected using the State Anxiety Scale, a vital signs and pain level form, and a descriptive characteristics form.",[312,27],"Anxiety",[314,315,316],"anxiety","vital signs","artroplasty","2024-12-12",{"date":319,"type":40},"2024-12-17",{"date":321,"type":40},"2024-08-01",{"date":323,"type":21},"2025-05",{"name":325,"class":47},"Suleyman Demirel University",{"id":327,"slug":328,"hasResults":11,"nctId":329,"briefTitle":330,"officialTitle":331,"acronym":332,"eligibilityCriteria":333,"healthyVolunteers":11,"sex":16,"minAge":334,"maxAge":4,"enrollmentInfo":335,"targetDuration":4,"studyType":22,"phases":337,"briefSummary":338,"conditions":339,"keywords":345,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":351,"lastUpdatePostDateStruct":352,"startDateStruct":354,"completionDateStruct":356,"leadSponsor":358,"locationsCount":48},"100527779","functional-outcome-after-orif-or-arthroplasty-for-femoral-neck-fracture-100527779","NCT06152198","Functional Outcome After ORIF or Arthroplasty for Femoral Neck Fracture","Internal Fixation Versus Hip Replacement in Older Adults with an Garden I\u002FII Femoral Neck Fracture: Physical Function and Pain in Elderly Patients - a Substudy of the Hipsther Trial","HipFunct","Inclusion Criteria:\n\n* Undisplaced (Garden I-II) femoral neck fracture (within 72h)\n* Treated at participating unit\n* Informed consent\n* Amenable for both treatment options\n* Included in the Hipsther trial\n\nExclusion Criteria:\n\n* No informed consent\n* Pathological or stress fracture\n* Peri-implant fracture\n* Previous inclusion of a contralateral Garden 1 or 2 femoral neck fracture","75 Years",{"count":336,"type":21},340,[24],"Aim To investigate the effect of internal fixation versus hip arthroplasty on physical function and pain in elderly patients.\n\nMethods This is a substudy of an on-going nationwide multicenter registry-based RCT named HipSTHeR- (Hip Screws or Total Hip replacement or undisplaced femoral neck fracture in elderly patients) \\[21\\]. The aim is to recruit 340 patients with undisplaced or minimally displaced femoral neck fracture, Garden 1 or 2, are randomized to surgery either with internal screw fixation or hip arthroplasty.\n\nThis substudy aims to investigate the potential differences between internal fixation versus hip arthroplasty regarding physical function and pain 4- and 12- months after surgery. Those included in the main study will be contacted by letter a few weeks after the surgery to be invited to participate in a further study. The assessor will then contact the person by telephone to answer further questions and to obtain informed consent. The follow-ups will be conducted over telephone and mail at 4 and 12 months. During the follow-up the participants will answer questions about their functional level.\n\nInformation on randomisation and fracture data will be acquired from the Swedish Fracture Register and treatment data from the Swedish Hip Arthroplasty Register.\n\nPrimary outcome The New Mobility Score will be used as the primary outcome with follow-up at 4- and 12 months.\n\nSecondary outcome WOMAC will be used as an additional hip specific patient reported outcome.\n\nActivities of daily living will be assessed with Katz ADL index to evaluate the patients' performance and the need of assistance in ADL.\n\nPatients' cognitive status will be assessed ALFI-MMSE, adapted from Adult Lifestyles and Function Interview (ALFI-MMSE).\n\nThe Geriatric Depression Scale (GDS-15), which are developed to identify depressive symptoms.\n\nThe Philadelphia Geriatric Center Morale Scale (PGCMS) and have been used in several studies including frail people living in residential care facilities and can be used among patients with cognitive impairment.",[340,341,342,343,344,27],"Hip Fractures","Femoral Neck Fractures","Undisplaced Fracture","Treatment Complication","Internal Fixation; Complications",[346,347,348,349,350],"hip fracture","femoral neck fracture","treatment","hip arthroplasty","internal fixation","2024-11-28",{"date":353,"type":40},"2024-12-03",{"date":355,"type":40},"2021-06-20",{"date":357,"type":21},"2027-09-01",{"name":359,"class":47},"Uppsala University",{"id":361,"slug":362,"hasResults":11,"nctId":363,"briefTitle":364,"officialTitle":364,"acronym":365,"eligibilityCriteria":366,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":367,"targetDuration":4,"studyType":22,"phases":369,"briefSummary":370,"conditions":371,"keywords":373,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":377,"lastUpdatePostDateStruct":378,"startDateStruct":379,"completionDateStruct":381,"leadSponsor":383,"locationsCount":48},"100539832","does-vessel-sparing-surgery-in-anterior-approach-total-hip-arthroplasty-change-clinical-outcome-100539832","NCT06308965","Does Vessel-sparing Surgery in Anterior Approach Total Hip Arthroplasty Change Clinical Outcome?","USP","Inclusion criteria To be eligible to participate in this study, a subject must meet all criteria below;\n\n* Scheduled for THA by Dr. Frans-Jozef Vandeputte or Professor Dr. Kristoff Corten\n* Provide signed and dated informed consent\n* Males or females age \\> 18 years\n\nExclusion criteria\n\nA potential subject who meets any of the following criteria will be excluded from participation in this study:\n\n* Neurological problems with sensorial and\u002For motoric disturbances (Multiple Sclerosis, Parkinson's disease, hemiplegia, …)\n* Previous surgery of the ipsilateral hip\n* Ipsilateral neck of femur fracture\n* Previous contralateral THA\n* Significant hip deformity: Crowe type 3 and 4 dysplasia, Leg-Calvé-Perthes\n* Avascular necrosis of the femoral head\n* Participating in another study that may interfere with participation in this study",{"count":368,"type":21},300,[24],"During direct anterior approach (DAA) for total hip arthroplasty (THA), ligation of the lateral femoral circumflex artery and vessel is always conducted. However, this standardized procedure may jeopardize blood muscle perfusion and cause tenderness in the tensor fascia lata muscle. The investigators want to investigate whether blood vessel-sparing surgery is feasible, reproducible, and would alter outcomes following DAA THA.\n\nThe surgical technique of the vessel-sparing procedure will be described and investigated in a prospective blinded RCT. The investigators hypothesize that the vessel-sparing technique is feasible in 60% of the patients. If these vessels were not sacrificed, the investigators expect the incidence of TFL tendinopathy to be lower.",[372,27],"Tensor Fasciae Latae Syndrome",[374,375,376],"Total Hip Arthroplasty","Ultra Sparing Procedure","Direct Anterior Approach","2024-11-12",{"date":71,"type":40},{"date":380,"type":40},"2024-06-11",{"date":382,"type":21},"2027-03",{"name":384,"class":47},"Ziekenhuis Oost-Limburg",{"id":386,"slug":387,"hasResults":11,"nctId":388,"briefTitle":389,"officialTitle":390,"acronym":391,"eligibilityCriteria":392,"healthyVolunteers":170,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":393,"targetDuration":4,"studyType":22,"phases":395,"briefSummary":396,"conditions":397,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":399,"lastUpdatePostDateStruct":400,"startDateStruct":402,"completionDateStruct":404,"leadSponsor":406,"locationsCount":48},"100416771","urinary-retention-after-arthroplasty-100416771","NCT04707001","Urinary Retention After Arthroplasty","Urinary Retention After Arthroplasty - UREA Trial","UREA","Inclusion Criteria:\n\n* elective total knee arthroplasty\n\nExclusion Criteria:\n\n* previous surgery for urologic cancer\n* fracture as indication for surgery\n* lack of co-operation\n* untreated urinary retention\n* nephrostoma\n* general anesthesia",{"count":394,"type":21},170,[24],"Arthroplasty increases the risk of postoperative urinary retention. Treatment of postoperative urinary retention is indwelling or intermittent catheterization. The need for catheterization is most commonly determined with an ultrasound scanner. Catheterization increases the risk of urinary tract infection, which may further lead to haematogenic infection of the artificial joint. There is no evidence of an optimal way to monitor the onset of spontaneous urination.\n\nThe aim of the study is to determine whether monitoring the onset of spontaneous urination after fast track knee arthroplasty is safe based on symptoms alone without ultrasound monitoring.",[398,27],"Urinary Retention Postoperative","2024-02-12",{"date":401,"type":40},"2024-02-13",{"date":403,"type":40},"2021-05-01",{"date":405,"type":21},"2026-07",{"name":407,"class":47},"Central Finland Hospital District",{"id":409,"slug":410,"hasResults":11,"nctId":411,"briefTitle":412,"officialTitle":413,"acronym":414,"eligibilityCriteria":415,"healthyVolunteers":11,"sex":16,"minAge":416,"maxAge":18,"enrollmentInfo":417,"targetDuration":4,"studyType":22,"phases":419,"briefSummary":420,"conditions":421,"keywords":423,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":430,"lastUpdatePostDateStruct":431,"startDateStruct":433,"completionDateStruct":435,"leadSponsor":437,"locationsCount":48},"100518046","is-mio-rsa-noninferior-to-bio-rsa-when-it-comes-to-mechanical-implant-stability-100518046","NCT06025448","Is MIO-RSA Noninferior to BIO-RSA When it Comes to Mechanical Implant Stability?","From Cuff Arthropathy to Reverse Shoulder Arthroplasty - a Multicentre Randomized Control Trial (CARS 2: Is MIO-RSA Noninferior to BIO-RSA When it Comes to Mechanical Implant Stability Measured With CT-based Motion Analysis (CTMA)?).","CARS-2","Inclusion Criteria:\n\n* Eligible for primary RSA due to OA, massive RC tear, failed RC repair or post-instability osteoarthritis\n* massive glenoid medialization\n* Able to read or write Norwegian\n\nExclusion Criteria:\n\n* Severe osteoporosis\n* Osteonecrosis of the humeral head\n* Dementia\n* Poor deltoid function\n* Revision surgery\n* ASA IV\n* Suspected chronic infection\n* Acute fracture","45 Years",{"count":418,"type":21},20,[24],"This clinical trial will investigate whether metallic lateralization in reverse shoulder arthroplasty is as stable as bony lateralization during the first two postsurgical years, measured with CT-based motion analysis (CTMA).",[27,422],"Shoulder Osteoarthritis",[424,425,426,427,428,429],"Reverse shoulder arthroplasty","BIO-RSA","MIO-RSA","Bony lateralization","Metallic lateralization","Orthopedic Surgery","2023-11-06",{"date":432,"type":40},"2023-11-07",{"date":434,"type":40},"2023-10-30",{"date":436,"type":21},"2033-03-01",{"name":438,"class":47},"Lovisenberg Diakonale Hospital"]