[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"artificial-cycle\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:artificial-cycle":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":5},"100628459","comparison-of-two-vaginal-progesterone-forms-in-frozen-embryo-transfer-100628459",false,"NCT07461909","Comparison of Two Vaginal Progesterone Forms in Frozen Embryo Transfer","Comparison of Patient Satisfaction, Convenience and Tolerability Between Two Vaginal Progesterone Formulations During Frozen Embryo Transfer","COPS","Inclusion Criteria:\n\n* Age: ≥18 and \\\u003C49 years old;\n* Body Mass Index (BMI) ≥18.5 Kg\u002Fm2 and \\\u003C30 Kg\u002Fm2;\n* Planned for single blastocyst stage transfer;\n* Has been prescribed two vaginal 200mg soft capsules or one 400mg pessary of progesterone, each 12hours before and after FET;\n* Either AC-FET or NPP-FET.\n\nExclusion Criteria:\n\n* Women who have previously enrolled in this study;\n* Those unable to comprehend the investigational nature of the proposed study;\n* Rank of FET\\>3;\n* Use of oral\u002Finjectable corticoids.","FEMALE","18 Years","48 Years",{"count":21,"type":22},400,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to compare two commonly used vaginal progesterone formulations - soft capsules versus pessaries - in women undergoing frozen embryo transfer (FET). The main question it aims to answer is:\n\n\\- Do soft vaginal progesterone capsules provide similar or better patient satisfaction, convenience, and tolerability compared with vaginal progesterone pessaries during preparation for frozen embryo transfer?\n\nParticipants undergoing FET who are prescribed vaginal progesterone as part of their endometrial preparation and luteal phase support will use one of the two formulations and complete patient-reported assessments regarding satisfaction, convenience, and tolerability. The study will also measure serum progesterone levels on the day of embryo transfer and evaluate pregnancy outcomes, including clinical pregnancy and live birth rates.",[26,27,28,29],"Frozen Embryo Transfer (FET)","Infertility","Artificial Cycle","Natural Cycle",[31,32,33,34,35,36,37,38,39],"Progesterone","Natural cycle","Natural proliferative phase (NPP-FET)","Artificial cycle (AC-FET)","Patient satisfaction","Frozen embryo transfer","Assisted reproduction","Endometrial preparation","Treatment tolerability","RECRUITING","2026-03-06",{"date":43,"type":44},"2026-03-10","ACTUAL",{"date":46,"type":44},"2024-11-08",{"date":48,"type":22},"2026-12",{"name":50,"class":51},"Instituto Valenciano de Infertilidade de Lisboa","NETWORK"]