[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"aseptic-loosening-of-orthopaedic-hardware\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:aseptic-loosening-of-orthopaedic-hardware":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100571429","mg-osteocrete-post-treatment-outcomes-100571429",false,"NCT06720142","Mg OSTEOCRETE Post-Treatment Outcomes","Clinical and Radiographic Outcomes of Patients Treated With Mg OSTEOCRETE","Inclusion Criteria:\n\n* 18 years of age and older on the day of surgery\n* has received or will receive Mg OSTEOCRETE as a component of their treatment at this institution in accordance with Instructions for Use for the implanted product\n* Mg OSTEOCRETE is indicated for one of the following reasons:\n\n  1. as a bone void filler following bone tumor resection, or;\n  2. as an augment for defects causing aseptic loosening of orthopaedic implants, or;\n  3. to help substitute bone for trauma-related conditions\n\nExclusion Criteria:\n\n* any contraindication as per Instructions for Use for Mg OSTEOCRETE","ALL","18 Years",{"count":19,"type":20},10,"ESTIMATED","OBSERVATIONAL","Mg OSTEOCRETE is a bone substitute used to fill a defect in bone caused by excision of a tumor, orthopaedic hardware that has become loosened, or a trauma-related condition. The aim of this study is to determine the amount of time it takes for bone to heal after treatment with Mg OSTEOCRETE, and to better understand the efficacy of this treatment through clinical and patient-reported outcomes.",[24,25,26],"Cancer of Bone","Trauma","Aseptic Loosening of Orthopaedic Hardware",[28,29,30],"bone defect","bone substitute","osteocrete","RECRUITING","2026-04-21",{"date":34,"type":35},"2026-04-22","ACTUAL",{"date":37,"type":35},"2025-03-17",{"date":39,"type":20},"2028-03-17",{"name":41,"class":42},"Santiago Lozano-Calderon","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":63,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":78},"100580631","digital-knee-study-adequately-diagnosing-total-knee-arthroplasty-loosening-by-evaluating-the-atmoves-knee-system-in-a-routine-clinical-setting-100580631","NCT06839807","DIGITAL-KNEE Study: Adequately Diagnosing Total Knee Arthroplasty Loosening by Evaluating the AtMoves Knee System in a Routine Clinical Setting","Adequately Diagnosing Total Knee Arthroplasty Loosening: A Randomized Controlled Trial Evaluating the AtMoves Knee System in a Routine Clinical Setting","DigitalKnee","Inclusion Criteria:\n\n* Age 18 years or older.\n* Subjects must have underwent either unilateral or bilateral TKA surgery.\n* Aseptic loosening is one of the differential diagnoses of the treating orthopaedic surgeon\n* The treating Orthopaedic Surgeon is uncertain of the diagnosis after anamnesis, physical examination and conventional x-ray.\n* The surgeon wants additional examinations or additional imaging to arrive at the diagnosis and proposal for treatment.\n* Subjects must be capable of giving informed consent and must be willing to undergo examination with the AtMoves Knee System.\n\nExclusion Criteria:\n\n* A clear other cause for complaints other than aseptic loosening (e.g. septic loosening, neuropathic pain, non-consolidated peri-prosthetic fracture of the bone around the TKA)\n* Surgical interventions of the index knee in the year prior to the start of the complaints associated with TKA loosening.\n* Posttraumatic or congenital deformation of the leg for which the loading device does not fit.\n* Pregnancy or suspected pregnancy.\n* Unable or unwilling to understand or sign the informed consent for this study and to undergo examination with the AtMoves Knee System.",{"count":53,"type":20},124,"INTERVENTIONAL",[56],"NA","The goal of the clinical trial is to evaluate the efficacy of the AtMoves Knee System in the clinical diagnostic process of aseptic loosening in patients with a knee prosthesis. The main question it aims to answer is:\n\nDoes the use of the AtMoves Knee System reduce the percentage of failed outcomes? A \"failed outcome\" is defined as a change in the patient-reported Knee injury and Osteoarthritis Outcome Score (KOOS-PS) that is lower than the minimal clinically important difference at 12 months.\n\nResearchers will compare two groups: The first group will undergo an additional CT scan using the AtMoves Knee System. The second group will not undergo these scans. Both groups are allowed to undergo additional diagnostic measures. Researchers will compare the percentage of \"failed outcomes\" between these groups.\n\nDuring the one-year follow-up, participants in both groups will be asked to fill out questionnaires.",[59,60,26,61,62],"Aseptic Loosening","Aseptic Loosening of Prosthetic Joint","Knee Arthroplasty, Total","Total Knee Arthroplasty (Replacement)",[64,65,66,67,68],"Aseptic loosening of total knee prosthesis","Aseptic loosening","Total knee arthroplasty","Aseptic loosening of prosthetic joint","Knee arthroplasty","2025-02-17",{"date":71,"type":35},"2025-02-21",{"date":73,"type":20},"2025-02",{"date":75,"type":20},"2026-06",{"name":77,"class":42},"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)",7]