[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"asynchrony-patient-ventilator\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:asynchrony-patient-ventilator":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":4},"100615362","synchrony-optimized-non-invasive-ventilation-education-program-and-icu-patients-100615362",false,"NCT07291622","Synchrony-Optimized Non-Invasive Ventilation Education Program and ICU Patients","Effect of a Synchrony-Optimized Non-Invasive Ventilation Education Program on Intensive Care Unit Patients' Outcomes: A Randomized Clinical Trial Protocol","Inclusion Criteria:\n\n* Adult patients over 18 years of age\n* Admitted to the ICU for at least 24 hours\n* Anticipated to be hospitalized for more than one week\n* Receiving NIV treatment for any underlying condition\n* Capable of learning\n* Proficient in the Persian language\n\nExclusion Criteria:\n\n* Patients with Richmond Agitation-Sedation Scale (RASS) scores of +4 or -5\n* Patients with cognitive disorders\n* Patients with neurological disorders\n* Patients with anxiety disorders\n* Patients whose condition deteriorates, making continued cooperation impossible\n* Patients unable to participate in educational sessions","ALL","18 Years",{"count":19,"type":20},92,"ESTIMATED","INTERVENTIONAL",[23],"NA","The aim of this clinical trial is to find out whether a synchrony-optimized education program for non-invasive ventilation (NIV) can help ICU patients use their ventilator more effectively and improve their comfort, symptoms, and psychological well-being.\n\nResearchers want to answer these main questions:\n\nCan a structured two-session NIV education program help patients use their ventilator more regularly and for longer periods?\n\nDoes this type of training reduce anxiety, depression, and respiratory symptoms?\n\nCan synchrony training improve patients' comfort and reduce NIV-related problems such as mask leaks or sleep disturbances?\n\nIs this program more effective than the routine ICU education normally provided?\n\nWhat Will Happen in the Study\n\nAdults (18+) who are receiving NIV in the ICU will participate in this study.\n\nParticipants will be randomly assigned to one of two groups:\n\nIntervention Group: Will receive the SYNC-NIV education program, consisting of:\n\nOne hands-on session (20-40 minutes) teaching patients how to synchronize their breathing with the ventilator\n\nOne supplementary session (45-60 minutes) covering mask management, preventing complications, reducing leaks, breathing exercises, equipment care, and alarm handling\n\nAn educational booklet for continued support\n\nControl Group: Will receive the standard ICU education normally provided about the ICU environment, general care, communication, and monitoring.\n\nAll participants will be evaluated at three times:\n\nbefore the intervention, the day after the program ends, and one week later.",[26,27,28,29],"Ventilator Associated Events","Asynchrony, Patient-Ventilator","Intensive Care (ICU)","Noninvasive Ventilation",[31,32,33,34,35,36],"Non-Invasive Ventilation","Patient-Ventilator Synchrony","Intensive Care Unit (ICU)","Anxiety and Depression","Randomized Clinical Trial","Patient Comfort","NOT_YET_RECRUITING","2025-12-17",{"date":40,"type":41},"2025-12-24","ACTUAL",{"date":43,"type":20},"2025-12-19",{"date":45,"type":20},"2026-01-10",{"name":47,"class":48},"Shahid Beheshti University of Medical Sciences","OTHER",{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":80},"100554063","comparison-of-different-methods-to-calculate-pendelluft-by-electrical-impedance-tomography-in-mechanically-ventilated-patients-100554063","NCT06494215","Comparison of Different Methods to Calculate Pendelluft by Electrical Impedance Tomography in Mechanically Ventilated Patients","Comparison of Different Methods to Calculate Pendelluft by Electrical Impedance Tomography in Patients Undergoing Invasive Mechanical Ventilation Under Pressure Support Mode","Inclusion Criteria:\n\n* Patients under invasive mechanical ventilation intubated due to respiratory failure in pressure support mode (weaning phase)\n\nExclusion Criteria:\n\n* Age less than 18 years; sedation or neuromuscular blockade; absence of respiratory effort; contraindications to esophageal balloon cathether positioning or electrical impedance tomography belt positioning; presence of pneumothorax or active air leaks; hemodynamic instability; absence of informed consent.",{"count":57,"type":20},15,[23],"The Pendelluft phenomenon is an important cause of lung damage in spontaneously breathing mechanically ventilated patients since it considerably increases the stress on the lung parenchyma in the dependent areas. It can result in a local driving pressure up to three times higher than the global driving pressure. The measurement of Pendelluft is still uncertain in the literature, and although various methods have been proposed, not all have the same meaning in terms of pulmonary overstress and overstrain. This study proposes a comparative analysis of different ways to calculate and estimate the stress imposed on the lung parenchyma by Pendelluft in terms of regional volume and local driving pressure through electrical impedance tomography.",[27,61,62,63],"ARDS","Respiratory Insufficiency","Respiratory Effort-Related Arousal | Patient | Respiratory Measures and Ventilator Management",[65,66,67,61,68,69],"Pendelluft","Ventilator-patient asynchrony","Patient self-induced lung injury","Respiratory failure","Electrical Impedance Tomography","RECRUITING","2024-07-02",{"date":73,"type":41},"2024-07-10",{"date":75,"type":41},"2024-06-11",{"date":77,"type":20},"2025-06-11",{"name":79,"class":48},"University of Sao Paulo General Hospital",1]