[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ataxic-cerebral-palsy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ataxic-cerebral-palsy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,80],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100625329","artemis---the-artemis-cohort-100625329",false,"NCT07421219","ARTEMIS - The ARTEMIS Cohort","Non-progressive Congenital Ataxia - Advancing Diagnosis to Enhance Chances for Targeted Therapy","ARTEMIS","Inclusion Criteria: • male or female children\n\n* confirmed diagnosis of NPCA\u002FAtaxic CP (SCPE definition)\n* aged ≥ 5 years and ≤ 8 years at time of data collection\n* written informed consent of at least one parent or legal representative in accordance to country regulations, and verbal assent of the child when possible\n\nExclusion Criteria: Children with all other diagnoses of movement disorders or other CP subtypes\n\n\\-","ALL","5 Years","8 Years",{"count":21,"type":22},50,"ESTIMATED","OBSERVATIONAL","This multinational European observational clinical study focuses on non-progressive congenital ataxia (NPCA), a very rare early-onset neurological condition also within the cerebral palsy (CP) concept as ataxic CP. The study aims to improve the diagnosis and care of affected children through a comprehensive approach that integrates detailed clinical assessments, brain imaging analyses, and advanced genetic testing. By identifying developmental trajectories, specific impairment profiles, brain MRI patterns, and genetic variants, the researchers aim to elucidate underlying mechanisms, origins and clinical heterogeneity of NPCA. The study also assesses the broader impact of the condition on the quality of life of affected children and the associated burden on their families. Preliminary data found a high prevalence of cognitive and neuropsychiatric impairments, and a frequent lack of identifiable brain lesions on MRI, raising the hypothesis of a strong genetic contribution.",[26,27],"Non-progressive Congenital Ataxia","Ataxic Cerebral Palsy",[26,27,29,30,31,32],"Genetic etiology","Neuroimaging","Neurodevelopmental disorders","Quality of Life","NOT_YET_RECRUITING","2026-02-11",{"date":36,"type":37},"2026-02-19","ACTUAL",{"date":39,"type":22},"2026-04",{"date":41,"type":22},"2027-12-31",{"name":43,"class":44},"Vastra Gotaland Region","OTHER_GOV",7,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":62,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":79},"100615324","effects-of-vojta-technique-on-ataxic-cerebral-palsy-100615324","NCT07291128","Effects of VOJTA Technique on Ataxic Cerebral Palsy.","Effects of VOJTA Technique on Muscle Tone, Gross Motor Function and Balance on Ataxic Cerebral Palsy.","Inclusion Criteria:\n\nBoth male and female participants would be included\n\nChildren diagnosed with ataxic cerebral palsy.\n\nAge range of participants will be 2 to 6 years old.\n\nParticipants included will be at level 2 on gross motor function classification scale.\n\nParticipants included will have ATNR reflex.\n\nStable medical condition for the past three months with no hospitalizations.\n\nExclusion Criteria:\n\nPresence of severe comorbidities i.e. neurological or orthopedic conditions.\n\nPatients having significant cognitive deficits\n\nDown syndrome, hydrocephalus, epilepsy, autism and medically ill children\n\nChildren with visual or auditory deficits affecting postural control and balance assessment.\n\nOngoing pharmacological treatment (e.g., muscle relaxants or antiepileptic) likely to influence muscle tone or motor function during the study period","2 Years","6 Years",{"count":56,"type":22},40,"INTERVENTIONAL",[59],"NA","Ataxic cerebral palsy (CP) is the least common subtype of CP and it is primarily caused by cerebellar damage that results in hypotonia, impaired balance, poor coordination, tremors, wide-based gait, and significant difficulties in trunk stability and uncontrolled movements. These impairments greatly affect functional mobility and independence in life. This randomized controlled trial aims to evaluate the effects of VOJTA therapy on muscle tone, gross motor function, and postural control in children with ataxic CP aged 2-6 years. VOJTA therapy is based on reflex locomotion, which activates innate central motor programs by stimulating specific pressure zones in defined positions, potentially improving postural alignment and coordinated muscle activation. A total of 40 children will be randomly assigned to either the VOJTA therapy group or a conventional physiotherapy group. Both groups will receive total of 5 sessions per week for 8 weeks and the Outcomes will be measured at baseline, 4 weeks, and 8 weeks using the Modified Ashworth Scale (MAS) for muscle tone, Gross Motor Function Measure (GMFM-88) for gross motor function and Pediatric balance scale for for balance. This study hypothesizes that VOJTA therapy will produce greater improvements in muscle tone, gross motor function and balance as compared to conventional physical therapy techniques. Findings may support evidence-based rehabilitation strategies for ataxic CP and contribute to improved functional independence and quality of life in this understudied population.",[27],[63,64,65,66,67],"vojta","muscle tone","ataxic cerebral palsy","gross motor function","balance","RECRUITING","2025-12-23",{"date":71,"type":37},"2025-12-30",{"date":73,"type":37},"2025-12-08",{"date":75,"type":22},"2026-05",{"name":77,"class":78},"Lahore University of Biological and Applied Sciences","OTHER",1,{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":57,"phases":89,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":79},"100565255","effects-of-hand-arm-bimanual-intensive-therapy-including-lower-extremity-on-balance-and-coordination-in-ataxic-cerebral-palsy-100565255","NCT06639802","Effects of Hand Arm Bimanual Intensive Therapy Including Lower Extremity on Balance and Coordination in Ataxic Cerebral Palsy","Inclusion Criteria:\n\n* Age group: 6 - 15 years.\n* Gender: Both males and females.\n* Cerebellar Ataxic cerebral palsy \\[10\\]\n* Gross motor function classification system level I and II.\n* Capable of following instructions and completing all necessary tests and tasks\n\nExclusion Criteria:\n\n* Uncontrolled epilepsy\n* Orthopedic surgery within the past 6 months,\n* Have visual, and hearing impairments (diagnosed).","15 Years",{"count":88,"type":22},23,[59],"Ataxic cerebral palsy is an abnormal movement or posture pattern accompanied by a loss of coordinated muscle action, resulting in movements that lack proper force, rhythm, or accuracy. Ataxic CP is classified into cerebellar ataxia and ataxic diplegia.\n\nIn Cerebellar Ataxia, the cerebellum is hypo-plastic or malformed which impairs the integration of brain signals required for coordinating coordinated movement and balance. This study aimed to determine the effect of HABIT-ILE on the balance and coordination of children with cerebellar ataxic cerebral palsy.",[27,92],"Coordination and Balance Disturbances",[94,95,27,96],"Physical Therapy Technique","coordination impairement","HAnd Arm Bimanual Intensive Therapy including Lower Extremity","2024-10-11",{"date":99,"type":37},"2024-10-15",{"date":101,"type":37},"2024-04-10",{"date":103,"type":22},"2024-12-01",{"name":105,"class":78},"Foundation University Islamabad"]