[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"atelectasis-postoperative\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:atelectasis-postoperative":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,50,77,99,132],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100626195","single-step-vs-stepwise-lung-recruitment-maneuvers-after-cardiopulmonary-bypass-100626195",false,"NCT07432477","Single-step vs Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass","Comparison of Hemodynamic and Pulmonary Outcomes Between Single-Step and Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 18-80 years\n* ASA (American Society of Anesthesiologists) II-IV\n* Patients undergoing elective cardiac surgery (coronary artery bypass grafting, mitral valve replacement, aortic valve replacement)\n\nExclusion Criteria:\n\n* Emergency surgery\n* Presence of perioperative arrhythmia\n* \\\u003C35% left ventricular ejection fraction\n* \\>50 mmHg systolic pulmonary artery pressure\n* Known chronic obstructive pulmonary disease or interstitial lung disease\n* Pneumothorax\n* Mean arterial pressure \\\u003C60 mmHg during recruitment maneuver\n* New York Heart Association (NYHA) class III-IV heart failure\n* Advanced cardiomyopathy or severe mitral regurgitation\n* Cross-clamp time longer than 2 hours\n* Requirement for high-dose inotropic or vasopressor support\n* Patients who cannot be extubated after postoperative 24 hours","ALL","18 Years","80 Years",{"count":20,"type":21},52,"ESTIMATED","INTERVENTIONAL",[24],"NA","This prospective randomized controlled trial aims to compare the hemodynamic and pulmonary effects of single-step and stepwise lung recruitment maneuvers in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass. After separation from cardiopulmonary bypass, patients will be randomized to receive either a single-step sustained inflation recruitment maneuver or a stepwise incremental recruitment maneuver, both combined with 8 cmH₂O positive end-expiratory pressure. The primary outcome is the change in cardiac index before and after the recruitment maneuver. Secondary outcomes include lung ultrasound atelectasis score, and hemodynamic parameters.",[27],"Atelectasis, Postoperative",[29,30,31,32,33,34,35,36],"cardiopulmonary bypass","lung recruitment maneuver","atelectasis","cardiac surgery","cardiac index","hemodynamics","lung ultrasound","positive end-expiratory pressure","RECRUITING","2026-06-30",{"date":40,"type":41},"2026-07-01","ACTUAL",{"date":43,"type":41},"2026-02-15",{"date":45,"type":21},"2027-05-01",{"name":47,"class":48},"Ondokuz Mayıs University","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":49},"100579454","ultrasound-for-postop-lung-issues-in-low-flow-anesthesia-100579454","NCT06824506","Ultrasound for Postop Lung Issues in Low-Flow Anesthesia","Evaluation of Early Postoperative Pulmonary Complications That Can be Detected by Ultrasonography in Patients Undergoing Laparoscopic Cholecystectomy With Low-flow Anesthesia","Inclusion Criteria:\n\n* Patients with informed consent\n* Patients scheduled for laparoscopic cholecystectomy\n* Patients with a Body Mass Index between 18-35 kg\u002Fm²\n* Patients in the American Society of Anesthesiologist (ASA) 1-2-3 category\n\nExclusion Criteria:\n\n* Patients with emergency surgery planned\n* Patients with ASA 4 and above\n* Patients with lung disease\n* Patients who have undergone thoracic surgery\n* Pregnancy\n* Patients with a preoperative Lung Ultrasound Score of 2 or 3 in any lung region",{"count":58,"type":21},110,"OBSERVATIONAL","Detecting possible atelectasis and other respiratory problems that may develop immediately after extubation via lung ultrasonography can reduce pulmonary complications by performing necessary interventions such as oxygen support, respiratory exercises, mobilization, and non-invasive mechanical ventilation applications at an early stage. In addition, although low-flow anesthesia is frequently used in daily anesthesia practice, publications showing the effects of its use in laparoscopic cholecystectomy operations on pulmonary complications are limited. On this occasion, this study can be presented as a contribution to the literature.",[27,62,63],"Cholecystitis; Gallstone","Pulmonary Atelectasis",[35,65,66],"low flow anesthesia","laparoscopic cholecystectomy","2026-06-04",{"date":69,"type":41},"2026-06-05",{"date":71,"type":41},"2025-02-15",{"date":73,"type":21},"2026-06-15",{"name":75,"class":76},"Ankara Ataturk Sanatorium Training and Research Hospital","OTHER_GOV",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":83,"minAge":17,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":49},"100620827","effects-of-ultrasound-guided-recruitment-manoeuvres-on-postoperative-pulmonary-complications-in-osa-patients-undergoing-total-laparoscopic-hysterectomy-100620827","NCT07362680","Effects of Ultrasound-guided Recruitment Manoeuvres on Postoperative Pulmonary Complications in OSA Patients Undergoing Total Laparoscopic Hysterectomy","Inclusion Criteria:\n\n* Age ≥ 18 years;\n* Scheduled for elective total laparoscopic hysterectomy;\n* American Society of Anesthesiologists (ASA) I to III;\n* BMI \\> 28 kg\u002Fm²;\n* STOP-BANG score ≥ 3.\n\nExclusion Criteria:\n\n* Abnormal findings on preoperative chest X-ray or CT, such as atelectasis, pneumothorax, thoracic deformity, pleural effusion, or neuromuscular diseases;\n* Pre-existing severe pulmonary diseases;\n* Severe cardiac arrhythmias or a history of cardiac surgery;\n* Allergy to any medications used in the study.","FEMALE",{"count":85,"type":21},90,[24],"This study aims to evaluate the lung-protective effects of ultrasound-guided lung recruitment maneuvers in patients with OSA undergoing total laparoscopic hysterectomy and to explore the efficacy of EELV measurement in assessing the effectiveness of these maneuvers.",[89,27],"Total Laparoscopic Hysterectomy","2026-01-15",{"date":92,"type":41},"2026-01-23",{"date":94,"type":41},"2025-05-02",{"date":96,"type":21},"2026-08-31",{"name":98,"class":48},"The First Affiliated Hospital of Xinxiang Medical College",{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":105,"eligibilityCriteria":106,"healthyVolunteers":107,"sex":16,"minAge":17,"maxAge":108,"enrollmentInfo":109,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":111,"conditions":112,"keywords":117,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":131},"100508869","diaphragm-dysfunction-and-ultrasound-perioperatively-100508869","NCT05906030","Diaphragm Dysfunction and Ultrasound Perioperatively","Diaphragm Dysfunction and Respiratory Complications in the Perioperative Setting- Can Diaphragm Ultrasound Aid Prediction?","DiaphPeriop","Inclusion Criteria:\n\nAdults undergoing elective (study 1) or acute (study 2) abdominal, pelvic or vascular surgery\n\nExclusion Criteria:\n\n* \\\u003C18 years\n* Underlying chronic respiratory disease\n* Patients not able to give informed consent",true,"100 Years",{"count":110,"type":21},160,"This study aims at determining whether diaphragm ultrasound examining diaphragm thickening fraction, excursion and density before and after surgery can predict respiratory complications in the postoperative period.\n\nPatients scheduled for major elective abdominal, pelvic or vascular surgery will be included in the study and diaphragm ultrasound is performed before surgery and after surgery in the postoperative ward. Physiological parameters, laboratory parameters, data on surgery and anesthesia and comorbidities will be registered. Complications such as pneumonia, desaturation, need for intubation and other respiratory events up to 30 days will be registered and later correlated with the diaphragm measurements.",[113,114,115,116,27],"Respiratory Insufficiency","Pneumonia","Desaturation of Blood","Tachypnea",[118,119,120,114,121],"Diaphragm dysfunction","Postoperative complication","Respiratory complication","Respiratory insufficiency","2025-01-27",{"date":124,"type":41},"2025-01-29",{"date":126,"type":41},"2024-09-01",{"date":128,"type":21},"2027-09-01",{"name":130,"class":48},"Karolinska University Hospital",2,{"id":133,"slug":134,"hasResults":11,"nctId":135,"briefTitle":136,"officialTitle":136,"acronym":4,"eligibilityCriteria":137,"healthyVolunteers":11,"sex":16,"minAge":138,"maxAge":18,"enrollmentInfo":139,"targetDuration":4,"studyType":22,"phases":141,"briefSummary":142,"conditions":143,"keywords":146,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":49},"100570097","physiological-effects-and-safety-of-continuous-high-frequency-oscillatory-ventilation-in-icu-patients-100570097","NCT06702813","Physiological Effects and Safety of Continuous High-frequency Oscillatory Ventilation in ICU Patients","Inclusion Criteria:\n\n* Patients older than 18 and younger than 90 years;\n* Admitted to the ICU after December 1, 2024, who are alert, with a GCS of 15, normal comprehension, and able to communicate clearly through speech or writing.\n* Patients with atelectasis, who are receiving oxygen therapy, high-flow oxygen, or are on a ventilator via tracheostomy.\n* Signed informed consent for MetaNeb treatment.\n\nExclusion Criteria:\n\n* Refusal to participate in the proposed study.\n* Age \\\u003C 10 years;\n* Pregnancy;\n* Significant hemodynamic instability defined as an increase of more than 20% in catecholamine doses in the last hour, despite optimization of blood volume, for a target mean blood pressure between 65 and 75 mmHg.\n* Participation in another trial within 30 days prior to meeting eligibility criteria;\n* Severe chronic respiratory disease requiring long-term oxygen therapy or home mechanical ventilation;\n* Pneumothorax. With a clear tracheoesophageal fistula","18 Months",{"count":140,"type":21},45,[24],"Atelectasis, hypoxemia, and ineffective sputum clearance are common problems in ICU patients. Continuous High-Frequency Oscillation (CHFO) is often considered to have a protective effect on the lungs. CHFO provides effective gas exchange at supraphysiological frequencies while minimizing pressure fluctuations, producing tidal volumes smaller than dead space, and adjusting around a continuously expanding pressure to optimize end-expiratory lung volume (EELV), thereby improving lung function by achieving and maintaining lung recruitment. However, the physiological effects and safety of CHFO in awake critically ill patients are still lacking relevant research. The objective of this study is to evaluate the comfort, safety, and efficacy of CHFO in awake critically ill patients.",[27,144,145],"Hypoxia","Critical Illness",[147,148,31],"HFOV","EIT","2024-11-21",{"date":151,"type":41},"2024-11-25",{"date":153,"type":21},"2024-11-19",{"date":155,"type":21},"2025-12-01",{"name":157,"class":48},"Shanghai Zhongshan Hospital"]