[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"atheromatous-plaques\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:atheromatous-plaques":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100603885","evaluation-of-atherectomy-in-the-management-of-occlusive-lesions-of-the-common-femoral-arteries-100603885",false,"NCT07142330","Evaluation of Atherectomy in the Management of Occlusive Lesions of the Common Femoral Arteries","Evaluation of Atherectomy in the Management of Occlusive Lesions of the Common Femoral Arteries (RAFAL)","RAFAL","Inclusion Criteria:\n\n* Male or female patient over 18 years of age\n* Non-emergency\n* Claudicating patient with significant de novo calcified stenosis affecting the common femoral artery, technically eligible for revascularization by thromboendarterectomy or rotational atherectomy\n* Surgery planned with either technique\n* Patient's consent to participate in the study must be obtained,\n\nExclusion Criteria:\n\n* Patient contraindicated for either technique (for surgical or anesthesiological reasons)\n* Patient with asymptomatic lesions of the common femoral artery\n* Patient with a history of surgery or angioplasty\u002Fstenting of the femoral stump\n* Patient with occlusion of the ipsilateral common femoral artery or external iliac artery\n* Patient with an indication for additional aortofemoral, iliofemoral, femoral-popliteal, or hamstring bypass\n* Patient with severe trophic disorders for which a major amputation is considered immediately in addition to revascularization\n* Patient objecting to the use of their data","ALL","18 Years",{"count":20,"type":21},120,"ESTIMATED","OBSERVATIONAL","Thromboendarterectomy is the standard technique for the treatment of symptomatic occlusive lesions of the common femoral artery. It consists of surgically controlling the artery and interrupting circulation, opening the vessel and removing the atherosclerotic plaque. However, this technique is associated with healing difficulties, postoperative infections, and debilitating incisional pain. The rise of endovascular therapies, particularly at the coronary level, has led to the emergence of new deocclusion techniques, including rotational atherectomy. This technique relies on the use of an intravascular catheter that reams out the atherosclerotic plaque while re-aspirating the resulting debris. A few studies have examined the use of rotational atherectomy for occlusive lesions of the common femoral arteries, but have not evaluated its results compared to the standard treatment. The aim of this multicenter cohort is to describe the efficacy and safety of rotational atherectomy and the standard treatment, thromboendarterectomy, in symptomatic occlusive lesions affecting the common femoral artery.",[25,26],"Femoral Artery Occlusion","Atheromatous Plaques","NOT_YET_RECRUITING","2025-08-19",{"date":30,"type":31},"2025-08-26","ACTUAL",{"date":33,"type":21},"2025-09-01",{"date":35,"type":21},"2026-09-01",{"name":37,"class":38},"Ramsay Générale de Santé","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":47,"enrollmentInfo":48,"targetDuration":4,"studyType":50,"phases":51,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":39},"100179308","phase-1-multimodal-imaging-assessment-of-the-inflammatory-atheromatous-plaque-100179308","NCT01608516","Multimodal Imaging Assessment of the Inflammatory Atheromatous Plaque","Multimodal Assessment of the Inflammatory Atheromatous Plaque : Comparison Between 68Ga-NODAGA-RGD PET\u002FCT, 18F-FDG PET\u002FCT, MRI AND US","Inclusion Criteria:\n\n* age \\\u003C= 85 years\n* Karnofsky \\>= 80%\n* patient with indication ofr carotid endarterectomy\n* signed consent form\n\nExclusion Criteria:\n\n* indication for surgery other than endarterectomy \\\u003C14 days\n* contraindication to surgery\n* contraindication to MRI\n* contraindication to gadolinium injection (stage 4\u002F5 kidney insufficiency, GFR\\\u003C30ml\u002Fmin\u002F1.73m2)\n* pregnancy, breastfeeding\n* lack of discernment","85 Years",{"count":49,"type":21},20,"INTERVENTIONAL",[52,53],"PHASE1","PHASE2","The present study aims at assessing the ability of 68Ga-NODAGA-RGD PET\u002FCT for the detection of inflammatory atheromatous plaques in the carotid arteries, compared to 18F-FDG PET\u002FCT, MRI and US and to determine the contribution of each imaging technique. Current gold standard for inflammation is histopathology.\n\nHypothesis : 68Ga-NODAGA-RGD might give a better initial evaluation of patients with atheromatous plaques in the carotid artery eligible for endarterectomy.",[56,26,57],"Inflammation","Carotid Artery Diseases",[59,60,61,62,63,64,65],"PET\u002FCT","68Ga-NODAGA-RGD","18F-FDG","MRI","US ultrasound","inflammatory atheromatous plaque","endarterectomy","RECRUITING","2024-06-17",{"date":69,"type":31},"2024-06-20",{"date":71,"type":31},"2012-04",{"date":73,"type":21},"2024-12",{"name":75,"class":38},"University of Lausanne Hospitals"]