[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"atrioventricular-nodal-reentry-tachycardia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:atrioventricular-nodal-reentry-tachycardia":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100462076","localization-of-anatomical-structures-involved-in-nodal-tachycardias-by-high-density-mapping-100462076",false,"NCT05296954","Localization of Anatomical Structures Involved in Nodal Tachycardias by High Density Mapping.","Localization of Anatomical Structures Involved in Nodal Tachycardias by High Density Mapping. Feasibility Study.","KOCH-MAPPING","Inclusion Criteria:\n\nGroup 1: Patients without heart disease presenting with reciprocal tachycardia by intra-nodal reentry.\n\nGroup 2: Control subjects, without nodal tachycardia, without heart disease, and admitted for ablation of atrial fibrillation or ventricular extrasystoles on a healthy heart and with a 3D system.\n\nExclusion Criteria:\n\n* Presence of underlying structural heart disease or history of atrial ablation or atrial tachycardia\n* Minor or protected patient\n* Patient under guardianship, curatorship or safeguard of justice","ALL","18 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of the present work is to analyze the capacity of high resolution mapping systems to determine the precise location of the AV node and peri-nodal slow-conducting pathways, using standard recording parameters, but also off-line additional filter changes and additional techniques (conduction velocities, isochrones and dV\u002Fdt). The investigative team plan a prospective monocentric study.\n\nDetailed high resolution mapping of the Koch triangle and neighboring areas will be collected through the RHYTHMIA HDx 3D electro-anatomical mapping system and the multipolar ORION catheter. This sample will consist of 2 groups of patients: the first will include patients referred for AVNRT ablation and the second will include control patients (without AVNRT), referred for another indication requiring similar mapping system. If visualized, position of the slow pathway and AV node will be compared with the ablation areas, which will be set conventionally under fluoroscopy.",[27,28],"Atrioventricular Nodal Reentry Tachycardia","Supraventricular Tachycardia",[30,31],"Voltage mapping","Atrioventricular node mapping","RECRUITING","2026-05-28",{"date":35,"type":36},"2026-06-01","ACTUAL",{"date":38,"type":36},"2022-02-04",{"date":40,"type":21},"2026-12",{"name":42,"class":43},"University Hospital, Toulouse","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":44},"100640090","nasval-svt-nasal-swab-versus-modified-valsalva-for-supraventricular-tachycardia-100640090","NCT07617077","NASVAL-SVT: Nasal Swab Versus Modified Valsalva for Supraventricular Tachycardia","A Randomized Controlled Trial Comparing Nasal Swab and Modified Valsalva Maneuver for the Treatment of Supraventricular Tachycardia","NASVAL-SVT","Inclusion Criteria:\n\n* Age 18 years or older\n* Electrocardiographically confirmed supraventricular tachycardia (SVT): narrow QRS complex (≤120 ms), regular rhythm, rapid ventricular rate, documented on 12-lead ECG or continuous cardiac monitoring\n* Hemodynamic stability, defined as ALL of the following simultaneously present:\n* Systolic blood pressure ≥90 mmHg\n* Diastolic blood pressure ≥60 mmHg\n* Alert and oriented mental status (GCS 15)\n* No signs of acute end-organ dysfunction\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Age younger than 18 years\n* Pregnancy (known or suspected)\n* Inability to confirm SVT diagnosis by ECG criteria\n* Delta wave or pre-excitation pattern on ECG (Wolff-Parkinson-White syndrome or asymptomatic pre-excitation) - due to risk of ventricular fibrillation with vagal maneuvers\n* Wide QRS tachycardia (QRS ≥120 ms) where ventricular tachycardia cannot be excluded\n* Absolute contraindication to modified Valsalva maneuver (inability to assume supine position or passive leg elevation)\n* Contraindication to nasal swab (nasal surgery within 30 days, active epistaxis, visible nasal polyp or mass)\n* Hemodynamic instability requiring immediate synchronized cardioversion\n* Prior enrollment in this study (re-presentation with SVT)\n* Refusal to participate",{"count":54,"type":21},60,[24],"Supraventricular tachycardia (SVT) is a common heart rhythm disorder seen in emergency departments, causing a rapid heartbeat (typically 150-250 beats per minute). The current best non-drug treatment, the modified Valsalva maneuver (mVM), successfully restores normal rhythm in about 43% of cases. When these maneuvers fail, intravenous adenosine is used, which, while effective, can cause brief but distressing side effects such as chest tightness, shortness of breath, and intense anxiety.\n\nDuring the COVID-19 pandemic, some patients briefly fainted during nasal swab collection. This happens because inserting a swab into the back of the nasal cavity (nasopharynx) stimulates the trigeminal nerve, which then activates the vagus nerve and slows the heart - a phenomenon called the trigeminocardiac (or nasocardiac) reflex. One published case report described a patient whose SVT was terminated within 10 seconds using a nasal swab.\n\nThis study compares the nasal swab technique with the modified Valsalva maneuver in patients presenting to the emergency department with SVT. Patients are randomly assigned to one of two groups. The primary outcome is whether a normal heart rhythm is restored within 1 minute of the procedure. Patient comfort and satisfaction are also measured.\n\nThe study is conducted in two phases. The first (pilot) phase (30 patients per group) will assess whether the study can be successfully conducted and collect data to finalize the required sample size. The second (main) phase will use the pilot phase's actual data to determine the final number of participants needed.",[28,58,27,59],"Paroxysmal Supraventricular Tachycardia","Vagal Maneuver",[61,62,63,64,65,66,67],"SVT","nasal swab","nasocardiac reflex","trigeminocardiac reflex","Valsalva maneuver","REVERT","emergency department","2026-05-23",{"date":35,"type":36},{"date":71,"type":36},"2026-05-01",{"date":73,"type":21},"2027-06",{"name":75,"class":43},"Marmara University Pendik Training and Research Hospital"]