[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"attention-deficit-disorder-with-hyperactivity-adhd\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:attention-deficit-disorder-with-hyperactivity-adhd":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,41,75,102,130,165,200,227,252],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100630398","unified-junction-of-care-integrated-treatments-and-team-coordination-for-adhd-in-prison-settings-with-substance-use-disorder-100630398",false,"NCT07487155","Unified Junction of Care, Integrated Treatments and Team Coordination for ADHD in Prison Settings With Substance Use Disorder","JUSTICE-TDAH","Inclusion Criteria:\n\n* Adult, under the supervision of the justice system or monitored by a correctional facility\n* Diagnosis of Substance Use Disorder (SUD)\n* Diagnosis of Attention Deficit Hyperactivity Disorder (ADHD)\n* No objection from the patient\n* Affiliated with a Social Security system\n\nExclusion Criteria:\n\n* Severe or decompensated psychiatric disorders\n* Severe cognitive impairment\n* Lack of understanding of the French language\n* Refusal to participate","ALL","18 Years",{"count":19,"type":20},39,"ESTIMATED","INTERVENTIONAL",[23],"NA","Substance use disorders (SUD) and attention deficit disorder with or without hyperactivity (ADHD) are frequently co-morbid, particularly among people under court supervision. The coexistence of these disorders increases the social and legal vulnerability of individuals. Better identification of ADHD in vulnerable people with SUD is essential to improving their care. This project aims to provide appropriate support for this at-risk population.",[26,27],"Attention Deficit Disorder With Hyperactivity (ADHD)","Substance Use Disorder (SUD)","NOT_YET_RECRUITING","2026-06-08",{"date":31,"type":32},"2026-06-10","ACTUAL",{"date":34,"type":20},"2026-07-01",{"date":36,"type":20},"2028-01-01",{"name":38,"class":39},"University Hospital, Brest","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":60,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":40},"100629020","behavioral-parent-training-with-and-without-ai-support-for-children-with-disruptive-behaviors-100629020","NCT07469215","Behavioral Parent Training With and Without AI Support for Children With Disruptive Behaviors","A Pilot Randomized Controlled Trial of Behavioral Parent Training (BPT) With or Without AI Support in Children With Disruptive Behaviors","Inclusion Criteria:\n\n* Being a primary caregiver with a child aged 5 to 12 years exhibiting disruptive behaviors (e.g., symptoms of ODD, CD, IED, ADHD, and\u002For unspecified behavioral problems).\n* Having access to an electronic device and regular internet access.\n* Stable concomitant intervention including medications throughout the study.\n* Speak Spanish or Catalan language.\n* Signed informed consent by parents or legal guardians of the child.\n\nExclusion Criteria:\n\n* Having ASD as primary diagnosis.\n* Psychosis, self-harming behaviors, severe mood disorder.\n* Known Intelligent quotient \\\u003C 70\n* Caregivers and\u002For children receiving any concurrent psychological treatment.\n* No signing the informant consent.","5 Years","12 Years",{"count":51,"type":20},40,[23],"The goal of this clinical trial is to learn if adding an artificial intelligence (AI) application called to standard Behavioral Parent Training (BPT) helps families with children who have disruptive behavior problems. It will also help researchers understand if the app is easy to use and helpful for parents.\n\nThe main question it aims to answer is:\n\n\\- Is it feasible and acceptable for parents to use the AI app alongside their therapy sessions?\n\nThe secondary questions it aims to answer are:\n\n* Does the app help reduce children's disruptive behaviors and irritability more than therapy alone?\n* Does using the app help lower stress, anxiety, and depression levels for the parents?\n\nResearchers will compare:\n\n1. Standard BPT: Parents receive 8 weekly group training sessions (online).\n2. BPT plus ParenteAI: Parents receive the same 8 weekly sessions plus 24\u002F7 access to an AI virtual assistant for personalized support.\n\nParticipants will:\n\n* Attend 8 weekly group training sessions.\n* Complete surveys about their child's behavior and their own well-being at baseline, after group training sessions 4 and 8, and 3 and 6 months after finalizing the group training.\n* If in the experimental group, use the ParenteAI app to get real-time coaching and support for managing their child's behavior at home.\n* Provide feedback on their experience and satisfaction with the program.",[55,56,57,58,59,26],"Behavior Problem of Childhood and Adolescence","Parent Management Training","Artificial Intelligence (AI)","Disruptive Behaviours","Irritability",[61,56,62,59,63,64],"Disruptive behaviors","Artifical intelligence","Behavior problems","Attention Deficit Disorder with Hyperactivity (ADHD)","RECRUITING","2026-03-09",{"date":68,"type":32},"2026-03-13",{"date":70,"type":20},"2026-04",{"date":72,"type":20},"2027-03",{"name":74,"class":39},"Fundació Sant Joan de Déu",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":16,"minAge":17,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":21,"phases":85,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":40},"100609674","investigating-mediodorsal-thalamus-representations-underlying-human-cognitive-flexibility-100609674","NCT07217652","Investigating Mediodorsal Thalamus Representations Underlying Human Cognitive Flexibility","Inclusion Criteria:\n\n* No history of any neurological, psychiatric, or medical condition that could affect cognition\n* No use of benzodiazepines, long-acting opioids, or other psychotropic drugs that could alter cognitive performance\n* Normal or corrected-to-normal vision (visual acuity)\n* Normal color perception (Farnsworth-Munsell 100 Hue Test)\n* Fluent in English\n* No metal implants (including aneurysm clip, cardiac pacemaker, ICD, IUD, neurostimulation system, spinal cord stimulator, internal electrodes or wires, bone stimulator, ear implant, insulin or other infusion pump or device, prosthesis, artificial or prosthetic limb, shunt, vascular access port or catheter, thermodilution catheter, medication patch, radiation seeds or implants, wire mesh implant, tissue expander, surgical staples or clips or sutures, joint replacement, joint\u002Fbone pin\u002Fscrew\u002Fnail\u002Fwire\u002Fplate, dentures, or non-removable hearing aid)\n* No exposure to shrapnel or other-related MR contraindications\n* No non-removable body piercing jewelry\n* No non-removable makeup\n* No history of claustrophobia\n* No history of breathing problems\n* Not currently pregnant or trying to get pregnant (this will be determined via self report and no records will be kept).\n\nExclusion Criteria:\n\n* Has a history of any neurological, psychiatric, or medical condition that could affect cognition\n* Use of benzodiazepines, long-acting opioids, or other psychotropic drugs that could alter cognitive performance\n* Not fluent in English\n* Known metal implants (including aneurysm clip, cardiac pacemaker, ICD, IUD, neurostimulation system, spinal cord stimulator, internal electrodes or wires, bone stimulator, ear implant, insulin or other infusion pump or device, prosthesis, artificial or prosthetic limb, shunt, vascular access port or catheter, thermodilution catheter, medication patch, radiation seeds or implants, wire mesh implant, tissue expander, surgical staples or clips or sutures, joint replacement, joint\u002Fbone pin\u002Fscrew\u002Fnail\u002Fwire\u002Fplate, dentures, or non-removable hearing aid)\n* History of claustrophobia\n* Currently pregnant or trying to get pregnant (this will be determined via self report and no records will be kept).",true,"35 Years",{"count":84,"type":20},100,[23],"The goal of this basic experimental research study is to examine how the human thalamus supports flexible thinking and behavior. Specifically, the research aims to elucidate how the mediodorsal (MD) thalamus encodes and updates \"context\"-the mental framework that determines which rules or actions are relevant in a given situation. This work may contribute to understanding why certain psychiatric conditions, such as schizophrenia and ADHD, involve difficulties with cognitive flexibility and control.\n\nThe primary research questions are:\n\nDoes the MD thalamus represent the context that organizes how working memory guides task selection? Does the MD thalamus signal when context needs to be updated after a change in task demands? Do these thalamic representations support generalization to new situations or rules?\n\nParticipants will complete cognitive tasks while undergoing high-resolution brain imaging using 7-Tesla MRI. The investigators will combine behavioral data, computational modeling, and advanced neuroimaging analyses to examine how the thalamus interacts with the cortex during flexible decision-making.",[88,26],"Schizophrenia",[90,91,92],"Cognitive control","working memory","decision making","2026-02-10",{"date":95,"type":32},"2026-02-13",{"date":97,"type":32},"2025-12-01",{"date":99,"type":20},"2030-07-30",{"name":101,"class":39},"Kai Hwang",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":108,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":16,"minAge":110,"maxAge":111,"enrollmentInfo":112,"targetDuration":4,"studyType":21,"phases":114,"briefSummary":115,"conditions":116,"keywords":118,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":40},"100609435","external-trigeminal-nerve-stimulation-for-children-with-asd--adhd-to-reduce-elevated-symptoms-100609435","NCT07214545","External Trigeminal Nerve Stimulation for Children With ASD + ADHD to Reduce Elevated Symptoms","Phase IIa Clinical Trial of External Trigeminal Nerve Stimulation for Autistic Children With Attention Deficit\u002FHyperactivity Disorder","eTNS CARES","Inclusion Criteria:\n\n* Confirmed clinician diagnosis of ASD according to DSM-5 criteria, corroborated by prior testing (or obtained in study screening) with the Autism Diagnostic Observation Schedule (ADOS) with or without the Autism Diagnostic Interview-Revised (ADI-R)\n* IQ \\> 70 as corroborated by prior testing (or obtained in study screening) with the Wechsler Abbreviated Scale of Intelligence Scale (WASI)\n* Confirmed diagnosis of ADHD according to DSM-5 criteria with minimum ADHD-RS score of \\> 24\n* Stable on current medications for a minimum of 4 weeks before baseline\n* Ability to complete protocol testing\n* Both the child participant and their primary caregiver must be fluent in English (speaking, reading, and understanding), as the questionnaires and assessment tools used in this study have been validated only in English.\n\nExclusion Criteria:\n\n* Current major depression, history of psychosis, bipolar disorder, elevated risk of self-harm\n* History of moderate to severe coarse brain injury\n* Active medical illness expected to interfere with study assessments\n* Presence of implanted stimulator (e.g., vagal nerve stimulator)\n* Active dermatologic condition likely to interfere with eTNS electrode wearability\n* Sleep disorder likely to interfere with nightly eTNS in the opinion of the study physician\n* Inability to communicate discomfort or pain\n* Current and anticipated continued use of antipsychotic or stimulant medication","7 Years","14 Years",{"count":113,"type":20},60,[23],"The goal of this clinical trial is to learn if external trigeminal nerve stimulation (eTNS) works to treat ADHD symptoms in children on the autism spectrum (ASD). It will also learn about the efficacy and tolerability of the eTNS device. The main questions it aims to answer are:\n\n* Does eTNS reduce ADHD symptoms?\n* Does eTNS improve core and associated features of ASD?\n\nParticipation spans 8-12 weeks and includes:\n\n* 4-5 in-person visits\n* 4 brief virtual check-ins\n* Nightly use of the eTNS device with a small sticky patch applied to child's forehead\n* Randomized assignment (those who start with the sham device may try the active device later)",[26,117],"Autism Spectrum Disorder (ASD)",[119,120,108],"eTNS","external trigeminal nerve stimulation","2025-10-07",{"date":123,"type":32},"2025-10-09",{"date":125,"type":32},"2025-10-06",{"date":127,"type":20},"2028-01-31",{"name":129,"class":39},"University of California, San Francisco",{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":136,"eligibilityCriteria":137,"healthyVolunteers":81,"sex":16,"minAge":138,"maxAge":139,"enrollmentInfo":140,"targetDuration":4,"studyType":141,"phases":4,"briefSummary":142,"conditions":143,"keywords":145,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":40},"100603418","a-quick-and-reliable-eye-movement-test-to-help-diagnose-adhd-in-children-100603418","NCT07136259","A Quick and Reliable Eye Movement Test to Help Diagnose ADHD in Children.","Certified Comprehensive Eye-Movement Examination in Children With Attention Deficit Hyperactivity Disorder: An Objective, Reproducible and Quantitative Diagnosis in 15 Minutes?","ADHDin15?","Inclusion criteria:\n\nFor the ADHD group:\n\n* Clinically confirmed diagnosis of ADHD by an expert (e.g., pediatrician, neuropsychologist, pediatric neurologist)\n* Age between 8 and 16 years\n* Written informed consent from the participant and\u002For legal guardian\n\nFor the control group (non-ADHD):\n\n* Age between 8 and 16 years\n* No suspicion of ADHD\n* Written informed consent from the participant and\u002For legal guardian\n\nExclusion Criteria:\n\nFor both groups:\n\n* Medical conditions known to affect ocular motor behavior (e.g., neurological or ophthalmological disorders)\n* Doubts regarding the accuracy of the ADHD diagnosis (for the ADHD group)\n* Lack of or questionable informed consent\n* Suspicion of ADHD in control group participants (reported by parents, examiner, or physician)","8 Years","16 Years",{"count":84,"type":20},"OBSERVATIONAL","Attention Deficit Hyperactivity Disorder (ADHD) affects more than 5 % of children and adolescents, with a globally increasing prevalence. The condition imposes a significant burden on affected individuals, their families, and healthcare systems. Early and accurate diagnosis is crucial to ensure timely therapeutic and educational interventions. However, current diagnostic practices rely heavily on clinical interviews and behavioral observations, which are inherently subjective and resource-intensive.\n\nThere is a growing need for objective diagnostic tools that can complement or even partially replace current clinical assessments. One promising approach involves eye-tracking technology, as ADHD is associated with altered oculomotor control and attention-related neural circuits. These changes may be reflected in measurable eye movement parameters, including saccadic latency and fixation stability.\n\nThis clinical investigation uses a certified, CE-marked medical eye-tracking device (neos™) to assess whether specific eye movement parameters can serve as objective biomarkers for ADHD. Although the device was originally designed to assess visual pathway integrity, it also captures parameters related to attention and executive function through standardized protocols. The test is examiner-independent, non-invasive, and takes approximately 10 minutes.\n\nThe study is observational and non-interventional, involving two groups of participants aged 8 to 16: 50 children with a clinically confirmed diagnosis of ADHD and 50 age-matched non-ADHD controls. All participants will complete a single neos™ eye-tracking assessment.\n\nThe primary hypothesis is that children with ADHD will demonstrate greater variability in saccadic latency and a higher frequency of large saccades (\\> 3°) during fixation compared to controls. These differences will be analyzed as potential diagnostic biomarkers. Diagnostic accuracy will be evaluated using receiver operating characteristic (ROC) analysis, with sensitivity, specificity and area under the curve (AUC) values reported.\n\nSecondary hypotheses include:\n\nOculomotor parameters derived from the neos™ system can distinguish between ADHD subtypes (predominantly inattentive, hyperactive-impulsive and combined).\n\nCombined oculomotor metrics correlate with ADHD symptom severity, potentially enabling a quantitative assessment of disease burden.\n\nThe results of this study could pave the way for the clinical adoption of objective, scalable and rapid diagnostic tools for ADHD. Beyond clinical use, such tools may also be adapted for population screening, telemedicine or integration into consumer-grade technologies such as virtual reality headsets. By validating a market-approved device for a new mental health indication, this study represents a critical step toward bridging research and clinical application in ADHD diagnostics.",[26,144],"Attention Deficit Disorder (ADD)",[146,147,148,149,150,151,152,153,154],"ADHD","Eye Tracking","Oculomotor Function","Pupillary Response","Pedriatic Neuropsychiatry","Neurodevelopmental Disorders","Neurocognitive Testing","Non-invasive Assessment","Eye Movements","2025-08-14",{"date":157,"type":32},"2025-08-22",{"date":159,"type":20},"2025-09-01",{"date":161,"type":20},"2026-01-31",{"name":163,"class":164},"Onovis Augenpraxis","NETWORK",{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":81,"sex":16,"minAge":172,"maxAge":4,"enrollmentInfo":173,"targetDuration":4,"studyType":21,"phases":175,"briefSummary":176,"conditions":177,"keywords":181,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":196,"leadSponsor":198,"locationsCount":4},"100578227","paiact-ai-driven-act-chatbot-for-mental-health-triage-and-service-evaluation-100578227","NCT06808555","Pai.ACT: AI-Driven ACT Chatbot for Mental Health Triage and Service Evaluation","Pai.ACT: An Artificial Intelligence-Driven Chatbot-Assisted ACT Mobile Platform With Mental Health Triage - A Randomized Controlled Trial and Regional Service Evaluation","Inclusion Criteria:\n\nThe participants of the study are primary caregivers, specifically parents, must be Cantonese-speaking residents of Hong Kong.\n\nEligible parents are required to cohabitate with a child aged 2 to 9 years who has either a confirmed or suspected diagnosis of a neurodevelopmental condition, including Autism Spectrum Disorder (ASD), Attention-Deficit\u002FHyperactivity Disorder (ADHD), or Developmental Delay (DD). These conditions must be recognised by the Child Assessment Service of the Department of Health and meet the diagnostic criteria specified in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). The diagnosis or suspected diagnosis must be formally documented in the child's case profile maintained at the collaborating non-governmental organisations.\n\nExclusion Criteria:\n\n* Parents diagnosed with severe mental illnesses.\n* Pregnant parents or those less than six months postpartum.\n* Parents with a developmental disability that impairs their ability to understand the program's content.\n* Parents with cognitive, language, communication, visual, or hearing impairments that could hinder their comprehension of the intervention content.\n* Parents actively participating in other psychosocial, psychoeducational, or parenting interventions.","19 Years",{"count":174,"type":20},340,[23],"Parents of children with special needs in Hong Kong often face limited psychological support, which can negatively impact the child rehabilitation process and the well-being of parent-child relationships. To address this gap, we have developed Pai.ACT, the first deep learning-based mental health advisory system for parents.\n\nPai.ACT features an AI chatbot that integrates the counselling principles of Acceptance and Commitment Therapy (ACT) through natural language processing, providing parents with a human-like voice-to-text experience. Using data from chatbot interactions, the Pai.ACT platform offers assessments regarding the individual's psychological inflexibility status and delivers stratified mental health interventions by:\n\n* Low-risk: Users access self-help ACT digital modules tailored to their specific psychological inflexibility processes.\n* Moderate-risk: In addition to the self-help modules, users receive 4-6 sessions of video-conferencing-based ACT interventions (45-60 minutes per session) conducted by our trained counseling team.\n* High-risk: Users are directed to specialized mental health services provided by collaborating units.\n\nThe study includes a regional randomised controlled trial (RCT) in Hong Kong's Sha Tin District, in collaboration with the Shatin District Office. The goal of this regional study is to evaluate the feasibility, acceptability, and potential efficacy of combining AI-driven mental health support across all of Hong Kong. Focus group interviews will also explore parents' perceptions of Pai.ACT and help identify the most effective service model for scaling its use.\n\nPai.ACT provides accessible and comprehensive mental health services to Chinese-speaking parents, helping to alleviate the psychological burden of caregiving. By integrating mental health support with child rehabilitation services and non-governmental organisations, Pai.ACT has the potential to enhance family caregivers' well-being, reduce stigma associated with special needs children, and promote more significant mental health awareness in Chinese-speaking communities.",[178,26,179,180],"Autism Spectrum Disorder","Neurodevelopmental Disorder (Diagnosis)","Dyslexia",[182,183,184,185,186,187,188,189,190,191],"Smartphone-delivered Therapy","Deep learning","Acceptance and Commitment Therapy","Parents","Children with Special Needs","Parental Support","Artificial Intelligence in Healthcare","Psychological Interventions","Parenting Stress","Regional Randomized Controlled Trial","2025-02-10",{"date":194,"type":32},"2025-02-12",{"date":192,"type":20},{"date":197,"type":20},"2027-02-28",{"name":199,"class":39},"Chinese University of Hong Kong",{"id":201,"slug":202,"hasResults":11,"nctId":203,"briefTitle":204,"officialTitle":205,"acronym":4,"eligibilityCriteria":206,"healthyVolunteers":81,"sex":16,"minAge":207,"maxAge":4,"enrollmentInfo":208,"targetDuration":4,"studyType":21,"phases":210,"briefSummary":211,"conditions":212,"keywords":213,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":219,"lastUpdatePostDateStruct":220,"startDateStruct":222,"completionDateStruct":224,"leadSponsor":226,"locationsCount":4},"100575987","paiact---an-artificial-intelligence-driven-chatbot-assisted-act-full-scale-rct-100575987","NCT06779422","Pai.ACT - An Artificial Intelligence Driven Chatbot Assisted ACT (Full Scale RCT)","Artificial Intelligence-driven, Chatbot-assisted Acceptance and Commitment Therapy (Pai.ACT) for Parents of Young Children With Neurodevelopmental Disorders: A Randomised Controlled Trial","Inclusion Criteria:\n\n* Primary caregivers who are Cantonese-speaking Hong Kong residents.\n* Parents aged ≥21 years.\n* Primary caregivers who adopt the responsibility of taking care of the child.\n* Living together with the child and having smartphone devices for daily access to the internet.\n* Parent's children should be with following criteria:\n\n  i) Aged 2-6 years. ii) Received a primary and clinical diagnosis\u002Fsuspected diagnosis of NDD as indicated in the clinical records according to the DSM-5 criteria. (e.g., ASD, ADHD, developmental delay) iii) Registered for Social Welfare Department subvented Onsite Pre-school Rehabilitation Services.\n\nExclusion Criteria:\n\n* Parents diagnosed with severe mental illnesses.\n* Parents with learning, cognitive, language, communication impairments or other debilitating conditions. (e.g., hearing or vision impairment) that could impede full participation in the study)\n* Parents currently participating in \u002Funder the evaluation of other psychosocial, psychoeducation or parenting programmes.","21 Years",{"count":209,"type":20},210,[23],"Interventions for parents of children with NDD face two pivotal challenges. Firstly, many overlook the consequential influence of parenting stress, symptoms of parental anxiety and depression on the well-being of parent-child dyads. Though some address parenting stress, they fall short of considering comprehensive health outcomes. Secondly, current evidence has supported ACT as an empirically validated, transdiagnostic psychotherapeutic intervention for parents with dual benefits for the parent-child dyads, but the treatment delivery (e.g., group-based and guided online approaches) is primarily in-person, demanding the presence of expert personnel in every session, limiting its scalability and accessibility. Unlike other psychotherapies like CBT and mindfulness, conventional ACT sessions often adopt a 'one-size-fits-all' strategy, using standardised and pre-packed exercises lacking the personalisation necessary to address individual variations in psychological inflexibility.\n\nLeveraging our available innovation, Pai.ACT, an AI-driven chatbot adopting the Focused ACT approach, seeks to offer personalised and scalable mental health solutions for Chinese-speaking parents of NDD children. With our encouraging preliminary data supporting our pre-trained NLP model's accuracy and Pai.ACT's feasibility, the investigators propose to examine Pai.ACT in a full-scale clinical trial. The study will examine the following research questions:\n\n1. Is Pai.ACT more effective than positive parenting advice for reducing parenting stress (primary outcome for parents) of parents and the emotional and behavioural symptoms of their young children with NDD (primary outcome for children) over the 12-month post-intervention follow-up?\n2. Is Pai.ACT more effective than positive parenting advice for reducing symptoms of depression and anxiety, improving parental psychological flexibility and parenting behaviour over the 12-month post-intervention follow-up?\n3. Is Pai.ACT more effective than positive parenting advice for reducing the use of healthcare and rehabilitation services in children with NDD over the 12-month post-intervention follow-up?\n4. What are the perceived benefits, satisfaction, strengths, and limitations of Pai.ACT from the parents' perspectives?",[151,117,26],[190,184,214,215,216,189,182,217,218],"Depression","Anxiety","Psychological flexibility","Mental well-being","Hong Kong","2025-01-21",{"date":221,"type":32},"2025-01-23",{"date":223,"type":20},"2025-02-13",{"date":225,"type":20},"2028-12-31",{"name":199,"class":39},{"id":228,"slug":229,"hasResults":11,"nctId":230,"briefTitle":231,"officialTitle":232,"acronym":4,"eligibilityCriteria":233,"healthyVolunteers":81,"sex":234,"minAge":4,"maxAge":4,"enrollmentInfo":235,"targetDuration":4,"studyType":21,"phases":237,"briefSummary":238,"conditions":239,"keywords":240,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":245,"startDateStruct":247,"completionDateStruct":248,"leadSponsor":250,"locationsCount":40},"100570130","pilot-study-on-a-health-promotion-intervention-for-ultra-orthodox-mothers-of-children-with-adhd-100570130","NCT06703242","Pilot Study on a Health Promotion Intervention for Ultra-Orthodox Mothers of Children With ADHD","Non-randomized Controlled Pilot Study of a Health Promotion Program for Mothers of Children in the Ultra-orthodox Community: Examining Feasibility","Inclusion Criteria:\n\n* mothers of children with ADHD aged 6- 12 years old\n* Mothers who identify as ultra-orthodox Jews\n* Child diagnosis was by a licensed medical professional\n\nExclusion Criteria:\n\n* Child medical diagnosis other than ADHD","FEMALE",{"count":236,"type":20},32,[23],"The goal of this study is to evaluate the feasibility and effectiveness of a health promotion intervention for Ultra-Orthodox Jewish mothers of children with ADHD.\n\nThis study will examine the impact of a culturally tailored group-based intervention aimed at reducing stress, enhancing health, and improving the well-being of mothers.\n\nThe main questions this study aims to answer are:\n\n1. Is the intervention feasible for mothers to participate?\n2. Does the intervention improve maternal knowledge about ADHD and reduce stigma?\n3. Does it help reduce maternal stress and enhance self-care practices?\n\nParticipants include:\n\nMothers: Ultra-Orthodox Jewish mothers with a child (ages 6-12) diagnosed with ADHD and no other major health conditions in the family (other than ADHD).\n\nEducators: School educators with at least 5 years of experience teaching children with ADHD in the Ultra-Orthodox community.\n\nWhat participation involves:\n\nMothers will attend six weekly teletherapy group sessions, with 6-8 mothers per group. They will complete questionnaires before and after the intervention (approximately 30 minutes each) and participate in a 90-minute remote focus group to provide feedback on the program.\n\nEducators will attend a single teletherapy group session (90 minutes) during the program (session 5) and participate in a 90-minute remote interview to provide feedback on the program.",[26],[241,242,243],"Mothering a child with ADHD","Maternal psychological health","Ultra-orthodox","2024-11-24",{"date":246,"type":32},"2024-11-27",{"date":244,"type":32},{"date":249,"type":20},"2025-05",{"name":251,"class":39},"Adina Maeir",{"id":253,"slug":254,"hasResults":11,"nctId":255,"briefTitle":256,"officialTitle":257,"acronym":4,"eligibilityCriteria":258,"healthyVolunteers":11,"sex":16,"minAge":259,"maxAge":260,"enrollmentInfo":261,"targetDuration":4,"studyType":21,"phases":263,"briefSummary":264,"conditions":265,"keywords":266,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":270,"lastUpdatePostDateStruct":271,"startDateStruct":273,"completionDateStruct":275,"leadSponsor":277,"locationsCount":40},"100568570","daily-routines-executive-functioning--adhd-100568570","NCT06682949","Daily Routines, Executive Functioning & ADHD","Daily Routines and Executive Functioning in Youth with ADHD","Inclusion Criteria:\n\n* Clinical diagnosis of attention-deficit\u002Fhyperactivity disorder (ADHD)\n* Located in the greater Tucson, AZ area\n* Must have a guardian willing to participate\n\nExclusion Criteria:\n\n* Clinical diagnosis of autism spectrum disorder\n* Clinical diagnosis of an intellectual disability\n* Clinical diagnosis of psychosis\n* Clinical diagnosis of bipolar disorder","11 Years","17 Years",{"count":262,"type":20},25,[23],"The goal of this clinical trial is to learn adjusting daily or nightly routines improves executive functioning in youth with ADHD. It will also learn about the acceptability of the intervention.\n\nThe main questions it aims to answer are:\n\n1. Does the intervention improve sleep for youth with ADHD?\n2. Does the intervention improve areas of executive functioning for youth with ADHD?\n3. Is this an acceptable intervention for youth with ADHD?\n\nResearchers will compare the two intervention conditions to see if their are impacts in executive functioning and sleep.\n\nParticipants will:\n\nComplete cognitive testing, executive function tasks, questionnaires, and an interview at baseline and at one month Wear an actigraph watch for one month Bring a parent with them to three meetings Complete daily sleep diaries for one month",[64],[146,267,268,269,91],"executive function","attention","adolescent","2024-11-21",{"date":272,"type":32},"2024-11-25",{"date":274,"type":32},"2024-11-04",{"date":276,"type":20},"2025-06",{"name":278,"class":39},"Cori Manning"]