[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"attention-deficit\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:attention-deficit":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100500932","neurocognitive-effects-of-non-invasive-near-infrared-light-stimulation-100500932",false,"NCT05802680","Neurocognitive Effects of Non-Invasive Near-Infrared Light Stimulation","Inclusion Criteria:\n\n* 18 years of age or older\n\nExclusion Criteria:\n\n* None",true,"ALL","18 Years",{"count":19,"type":20},500,"ESTIMATED","INTERVENTIONAL",[23],"NA","Inattentiveness and impulsivity in healthy adults and individuals with attention deficit hyperactivity disorder (ADHD) diminish these individuals' quality of life. Cortical hypometabolism has been hypothesized to contribute to inattentiveness in ADHD. Transcranial photobiomodulation (tPBM) is a safe and non-invasive modality for activation of the prefrontal cortex. tPBM in healthy adults has been shown to augment brain oxygenation, cognition, and mood. The cognition-enhancing effect of tPBM on sustained attention in adults with ADHD remains unstudied. The investigators will evaluate whether tPBM administration to adults with and without ADHD can improve their attention. Each participant will be screened for eighteen criteria based on the Diagnostic and Statistical Manual (DSM-IV, text revised), using the validated instrument Adult ADHD Self-Report Scale (ASRS-v1.1). Blinded participants will be randomized into (I) Active-tPBM or (II) Sham-tPBM groups. After undergoing an 8-minute administration of Sham or 1064 nm tPBM to the lateral and medial right prefrontal cortex, each participant will complete a 14-minute, computer-based Conner's continuous performance task-3 (CPT-3). The investigators will examine whether adults with and without ADHD who receive Active-tPBM improve in measures of inattention, impulsivity, sustained attention, or vigilance compared to the Sham-tPBM group. Cognitive assessments of attention like the CPT-3 may evaluate the efficacy of tPBM to increase cortical metabolism in healthy adults and individuals with conditions like ADHD. The investigators anticipate their investigation will be a starting point for more sophisticated studies that focus on the implications of tPBM on cognition.",[26,27,28,29,30],"Attention Deficit Hyperactivity Disorder","Attention Difficulties","Attention Deficit","Cognitive Deficit","Wellness","RECRUITING","2026-06-17",{"date":34,"type":35},"2026-06-22","ACTUAL",{"date":37,"type":35},"2022-02-09",{"date":39,"type":20},"2027-02-01",{"name":41,"class":42},"Francisco Gonzalez-Lima, PhD","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":43},"100446933","feasibility-and-efficacy-of-attentional-control-training-in-sickle-cell-disease-100446933","NCT05099874","Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease","ACT","Inclusion Criteria:\n\n* diagnosis of SCD\n* ages 8-16 years\n* maintained on monthly blood transfusions consistently for at least 3 months.\n* patients will be proceed to the intervention phase only if they have a T-score \\> 75th percentile for Omission Errors on the Conners' Continuous Performance Test, 3rd Edition (CPT-3) or a T-score \\> 75th percentile for the Inattention subscale of the ADHD Rating Scale, Fifth Edition (ADHD-RS-V).\n\nExclusion Criteria:\n\n* estimated Intelligence Quotient \\\u003C 70\n* motor, visual, or auditory impairment that prevents computer use\n* known diagnosis of a mental health condition that precludes, or takes treatment precedence over, participation in cognitive training\n* history of photosensitive seizures\n* insufficient English fluency.","8 Years","16 Years",{"count":54,"type":20},20,[23],"Children with sickle cell disease (SCD) exhibit significantly reduced cognitive functioning (often difficulties with attention) compared to peers and siblings without SCD. EndeavorRx (Akili Interactive Labs: Boston, MA) is an FDA-approved home-based, electronic attentional-control training program designed to treat attention problems in youth. Users access EndeavorRx on a tablet device for 25-30 minutes each day, 5 days per week, for 4 weeks. The program involves training in a game-like environment that repeatedly challenges attentional-control abilities and adapts to user performance, becoming more difficult over time as performance improves. This pilot study is examining the feasibility, acceptability, and preliminary efficacy of EndeavorRx in a sample of 20 children with SCD ages 8-16 who are being treated with chronic blood transfusion therapy.",[58,28,59],"Sickle Cell Disease","Cognitive Deficit in Attention","2025-01-08",{"date":62,"type":35},"2025-01-10",{"date":64,"type":35},"2022-12-20",{"date":66,"type":20},"2025-12",{"name":68,"class":42},"Children's National Research Institute",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":21,"phases":80,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":94},"100510301","neurofeedback-trainings-efficiency-for-attentionnal-performances-100510301","NCT05924659","Neurofeedback Training's Efficiency for Attentionnal Performances","Evaluation of Neurofeedback Training's Efficiency for the Optimization of Attentionnal Performances","ENOCA","Inclusion Criteria:\n\n* healthy male or female volunteers\n* aged between 18 yo and 50 yo.\n\nExclusion Criteria:\n\n* any pathological issues,\n* previous traumatic brain and\u002For auditive injuries,\n* volunteers having already experienced NFB trainings,\n* high tobacco consumers,\n* volunteers refusing genotyping.","59 Years",{"count":79,"type":20},108,[23],"This randomised, double bling and controled study aim to evaluate the performance of a neurofeedback training on attentional capabilities, in comparison to placebo. We hypothesize 1) that an electroencephalographic (EEG) based neurofeedback training may improve attentional performances of healthy subjects, and 2) inter-individual variability might be explained by factors such as body awarness, sleep parameters and genetics of individuals.",[83],"Attention-deficit","2024-06-19",{"date":86,"type":35},"2024-06-24",{"date":88,"type":35},"2023-06-25",{"date":90,"type":20},"2024-08-01",{"name":92,"class":93},"Institut de Recherche Biomedicale des Armees","OTHER_GOV",2]