[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"attention-difficulties\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:attention-difficulties":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,65],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100500932","neurocognitive-effects-of-non-invasive-near-infrared-light-stimulation-100500932",false,"NCT05802680","Neurocognitive Effects of Non-Invasive Near-Infrared Light Stimulation","Inclusion Criteria:\n\n* 18 years of age or older\n\nExclusion Criteria:\n\n* None",true,"ALL","18 Years",{"count":19,"type":20},500,"ESTIMATED","INTERVENTIONAL",[23],"NA","Inattentiveness and impulsivity in healthy adults and individuals with attention deficit hyperactivity disorder (ADHD) diminish these individuals' quality of life. Cortical hypometabolism has been hypothesized to contribute to inattentiveness in ADHD. Transcranial photobiomodulation (tPBM) is a safe and non-invasive modality for activation of the prefrontal cortex. tPBM in healthy adults has been shown to augment brain oxygenation, cognition, and mood. The cognition-enhancing effect of tPBM on sustained attention in adults with ADHD remains unstudied. The investigators will evaluate whether tPBM administration to adults with and without ADHD can improve their attention. Each participant will be screened for eighteen criteria based on the Diagnostic and Statistical Manual (DSM-IV, text revised), using the validated instrument Adult ADHD Self-Report Scale (ASRS-v1.1). Blinded participants will be randomized into (I) Active-tPBM or (II) Sham-tPBM groups. After undergoing an 8-minute administration of Sham or 1064 nm tPBM to the lateral and medial right prefrontal cortex, each participant will complete a 14-minute, computer-based Conner's continuous performance task-3 (CPT-3). The investigators will examine whether adults with and without ADHD who receive Active-tPBM improve in measures of inattention, impulsivity, sustained attention, or vigilance compared to the Sham-tPBM group. Cognitive assessments of attention like the CPT-3 may evaluate the efficacy of tPBM to increase cortical metabolism in healthy adults and individuals with conditions like ADHD. The investigators anticipate their investigation will be a starting point for more sophisticated studies that focus on the implications of tPBM on cognition.",[26,27,28,29,30],"Attention Deficit Hyperactivity Disorder","Attention Difficulties","Attention Deficit","Cognitive Deficit","Wellness","RECRUITING","2026-06-17",{"date":34,"type":35},"2026-06-22","ACTUAL",{"date":37,"type":35},"2022-02-09",{"date":39,"type":20},"2027-02-01",{"name":41,"class":42},"Francisco Gonzalez-Lima, PhD","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":15,"sex":16,"minAge":50,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":21,"phases":53,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":43},"100503412","effects-of-neurofeedback-and-transcranial-pulse-stimulation-on-attention-100503412","NCT05834920","Effects of Neurofeedback and Transcranial Pulse Stimulation on Attention","Inclusion Criteria:\n\n* Aged 20 years and above\n* Right-handed\n* Normal\u002Fcorrected hearing and vision\n* Having basic literacy skills\n* Having sustained attention scores below the threshold\n\nExclusion Criteria:\n\n* Having medical history related to brain\n* Having mild cognitive impairment\n* Showing symptoms of depression and anxiety\n* Having intellectual disability based on IQ scores\n* Having diagnoses of any psychiatric or cognitive disorders besides attention deficit hyperactivity disorder (ADHD) inattentive and combined types\n* Having long-term history of smoking cigarettes\n* Engaged in alcohol and\u002For substance abuse\n* Having history of hemophilia or other blood clotting disorders or thrombosis\n* Having corticosteroid treatment within the last six weeks before first intervention\n* Having contraindications for MRI scanning","20 Years",{"count":52,"type":20},180,[23],"The present study aims to examine and compare the effectiveness of transcranial pulse stimulation and neurofeedback among adults who are weak in attention.",[27],"2025-02-28",{"date":58,"type":35},"2025-03-05",{"date":60,"type":35},"2023-03-17",{"date":62,"type":20},"2025-06",{"name":64,"class":42},"The University of Hong Kong",{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":11,"sex":16,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":4,"studyType":21,"phases":77,"briefSummary":78,"conditions":79,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":43},"100479896","feasibilityacceptability-of-attentional-control-training-in-survivors-100479896","NCT05528939","Feasibility\u002FAcceptability of Attentional-Control Training in Survivors","FAACTS: Feasibility\u002FAcceptability of Attentional-Control Training in Survivors","FAACTS","Inclusion Criteria:\n\n* Aged 8-16 years at time of screening.\n* History of diagnosis of acute lymphoblastic leukemia (ALL) or brain tumor (BT).\n* At least 1 year from completion of planned therapy and stable from a disease standpoint.\n* Participating child and caregiver are fluent in spoken English.\n* Availability of a caregiver who is willing and capable of providing support and supervision during cognitive training.\n* Participating child is either not taking any prescribed stimulant medication for attention difficulties or has been prescribed a stable dose of stimulant medication for attention difficulties for at least 30 days prior to enrollment.\n* Only patients with a T-score ≥ 75th percentile on the CPT-3 Omission Errors scale or on the BRIEF-2 Cognitive Regulation Index will be randomized.\n\nExclusion Criteria:\n\n* A history of photosensitive seizures.\n* A motor, visual, or auditory handicap that prevents computer use.\n* A mental health condition that precludes, or takes treatment precedence over, participation in the cognitive training.\n* Participants identified during the baseline assessment as having a full-scale IQ \\\u003C 80, as estimated by WASI-II (Vocabulary and Matrix Reasoning), will not be randomized.","8 Years","16 Years",{"count":76,"type":20},50,[23],"This is a multicenter pilot randomized controlled trial, with an active control condition, of the feasibility, acceptability, and preliminary efficacy of EndeavorRx in a cohort of survivors of acute lymphoblastic leukemia or brain tumor ages 8-16 who are \\> 1 year from the end of therapy.",[80,81,82,27,83],"Pediatric Cancer","Pediatric ALL","Pediatric Brain Tumor","Cognitive Deficit in Attention","2025-01-08",{"date":86,"type":35},"2025-01-10",{"date":88,"type":35},"2023-06-14",{"date":90,"type":20},"2025-08-31",{"name":92,"class":42},"Children's National Research Institute"]