[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"augmentative-and-alternative-communication\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:augmentative-and-alternative-communication":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100606245","speech-production-enhancement-using-augmentative-communication-for-kids-100606245",false,"NCT07173049","Speech Production Enhancement Using Augmentative Communication for Kids","Speech Supplementation Strategies for Improving Intelligibility in Children With Cerebral Palsy (CP)","SPEAK","Inclusion Criteria:\n\n* Medical diagnosis of cerebral palsy, or a similar, related condition that affects early motor development and presents as a chronic motor disability\n* Age between 7 and 17 years\n* Clinical dysarthria with speech intelligibility between 10-85 percent\n* Able to produce connected speech in English, with a minimum utterance length of 3 words\n* Able to use hands to point to items on a communication board\n* Cognitive\u002Flanguage skills that enable basic picture identification on a communication board\n* Pass pure tone hearing screening\n\nExclusion Criteria:\n\n* Failure to meet all inclusion criteria.\n* Vision impairment that precludes being able to see items on a communication board.\n* Not suitable for participation due to other reasons at the discretion of the investigators.","ALL","7 Years","17 Years",{"count":21,"type":22},100,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to learn if speech supplementation can improve speech intelligibility in children ages 7 to 17 years with cerebral palsy. The main questions it aims to answer are:\n\n* To what extent can speech supplementation improve intelligibility in children with CP compared with habitual speech produced without speech supplementation?\n* How much intelligibility change is necessary for meaningful improvement when children use speech supplementation strategies?\n\nParticipants will:\n\n* complete speech and language assessments\n* complete a speech pre-test using habitual speech\n* learn a speech supplementation strategy with training from a speech-language pathologist\n* complete a speech post-test using the speech supplementation strategy\n* complete a speech repetition task where specific words are emphasized (emphatic stress)\n* use the previously learned speech supplementation strategy + emphasis on specific words while producing a set of sentences",[28,29,30],"Cerebral Palsy (CP)","Intelligibility, Speech","Augmentative and Alternative Communication",[32,33,34,35,36],"Cerebral Palsy","Speech","Intelligibility","Speech supplementation","Augmentative and alternative communication","RECRUITING","2026-05-28",{"date":40,"type":41},"2026-06-01","ACTUAL",{"date":43,"type":22},"2026-07",{"date":45,"type":22},"2029-07",{"name":47,"class":48},"University of Wisconsin, Madison","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":49},"100595948","using-a-speech-generating-device-to-support-communication-in-rare-genetic-conditions-100595948","NCT07039084","Using a Speech-Generating Device to Support Communication in Rare Genetic Conditions","A Randomized Cross-over Trial Examining the Efficacy of Implementing a Speech-generating Device for Rare Genetic Conditions","Inclusion Criteria:\n\n* Is between the ages of 3 and 12 years, inclusive, at the time of enrolment\n* Has a diagnosis of a rare genetic disorder\n* Passes a visual-motor screening test, therefore being able to tap on an iPad spontaneously or by imitation and has adequate hearing\n* Considered \"minimally verbal\" with less than 50 spontaneous words (or gestalts) at baseline assessments, confirmed with the LVIS.\n* Is not currently using a speech-generating device with proficiency (i.e. using the device as a main mode of communication on a daily basis).\n* Is English-speaking or consents to therapy being conducted in English (parents will need to be able to complete the parent-reported measures in English)\n\nExclusion Criteria:\n\n* Has an additional or dual genetic variation (as this is likely to cause multiple complications and increase variability),\n* Is extremely ill or has progressed into a later stage of their disease (i.e. child has clinically significant loss of vision, hearing, fine motor skills, or is unable to adequately attend sessions due to illness),\n* This is to ensure treatment is beneficial, reduce harm and reduce attrition rates.\n* Lives outside of the state of Victoria (making it difficult for in-person appointments)\n* Inability or unwillingness of participant or legally acceptable representative to give written informed consent.","3 Years","12 Years",{"count":60,"type":22},38,[25],"Individuals with rare genetic conditions may experience a delay or loss of developmental skills. Many have limited verbal speech. The aim of this clinical trial is to examine how well a speech-generating device supports the communication skills of participants with a rare genetic condition. The speech-generating device is a communication program loaded onto an iPad.\n\nThis is a crossover trial, meaning that each participant will receive both the treatment (device) and a control (usual care; no device) phase. The order in which each participant receives the device versus the usual care (no device) will depend on which group the participant is assigned to. The changes in communication in each phase will then be compared.\n\nDuring the trial, participants can expect to complete a series of assessments and attend a total of 2 x 1-hour therapy session per week for 6 weeks.",[64,65,30,66,67],"Genetic Disease","Nonverbal Communication","Rare Genetic Disease","Rare Genetic Disorders","2026-05-21",{"date":70,"type":41},"2026-05-26",{"date":72,"type":41},"2025-11-03",{"date":74,"type":22},"2027-05",{"name":76,"class":48},"Murdoch Childrens Research Institute"]