[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"auto-immune-hepatitis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:auto-immune-hepatitis":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100574586","is-negativity-of-autoantibodies-a-marker-of-severity-in-auto-immune-hepatitis-100574586",false,"NCT06761209","Is Negativity of Autoantibodies a Marker of Severity in Auto-immune Hepatitis?","Is Negativity of Autoantibodies a Marker of Severity in Auto-immune Hepatitis","HAI-NEG","Inclusion Criteria:\n\n* \\- Any patient over 18 years old\n* Patient followed at Hôpital Saint-Antoine or treated for HAI or in Guadeloupe within the framework of the CCRD Filfoie for an acute or chronic AIH under immunosuppressive treatment\n* Patient affiliate or beneficiary of a social security scheme\n* Free, informed and written consent signed by the patient and the investigator\n\n  o exclusion criteria: - Patient under 18 years old\n* Patient not able to give his\u002Fher consent\n* Viral hepatitis: viruses A to E, Epstein-Barr virus, cytomegalovirus and herpes simplex virus\n* Isolated primary biliary cholangitis\n* Isolated primary sclerosing cholangitis\n* Drug-induced liver injury\n* Wilson disease\n* Alcoholic hepatitis\n* Hemochromatosis\n* Sickle cell disease and heart liver\n* Non-alcoholic steato-hepatitis","ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","OBSERVATIONAL","Evaluate the proportion of seronegative auto-immune hepatitis and a possible relationship with the severity of the disease. Criteria of severity will be defined by corticodependance, corticoresistance and a severe form of the disease at diagnosis (cirrhosis or fulminant hepatitis). In case of predominant seronegative forms, other auto-antibodies related to this auto-immue hepatitis will be searched.",[25],"Auto-immune Hepatitis",[27,28,29,30],"autoantibodies","auto-immune hepatitis","prognosis","afrocaribbean population","RECRUITING","2024-12-30",{"date":34,"type":35},"2025-01-07","ACTUAL",{"date":37,"type":35},"2022-07-01",{"date":39,"type":21},"2026-12",{"name":41,"class":42},"Centre Hospitalier Universitaire de la Guadeloupe","OTHER",2]