[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"autonomic-neuropathy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:autonomic-neuropathy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100386354","autonomic-small-fiber-neuropathy-and-ehlers-danlos-syndromes---prospective-study-and-registry-100386354",false,"NCT04310644","Autonomic Small Fiber Neuropathy and Ehlers Danlos Syndromes - Prospective Study and Registry","Autonomic Neuropathy and Its Pathophysiology in Autoimmune Autonomic Neuropathies, Postural Orthostatic Tachycardia Syndrome and Ehlers Danlos Syndromes: Peripheral Autonomic Small Fiber Neuropathy or Central Autonomic Failure? Validation of the Malmö POTS Score and a Better Diagnosis of POTS in Patientes With Autnomic Failure (VaGeMAPS-3-step-Diag)","ProANS","Inclusion Criteria:\n\n* autonomic neuropathy\n* Postural orthostatic tachycardia syndrome\n* hypermobile or classical Ehlers Danlos syndromes\n* Chronic fatigue syndrome, mast cell activation syndrome and\u002For PostCOVID\n* healty controls\n* between 18-80 years\n* in patients: diagnosis and clinical testing in our outpatient clinic\n* German speaking\n\nExclusion Criteria:\n\n* pregnancy\n* Pacemaker or Deep brain Stimulation\n* sensory or motor Polyneuropathy\n* neurodegenerative disease","ALL","18 Years","80 Years",{"count":21,"type":22},200,"ESTIMATED","5 Years","OBSERVATIONAL","We examine patients with different autonomic neuropathies and Ehlers Danlos syndromes compared to healthy controls at three different points over time (baseline, after 3 months and after 1.5 years) to gain knowledge about the course of this disease and understand its pathophysiology, with a focus on Small Fiber neuropathy. Moreover we will validate the german version of the Malmö POTS Score and establish an easy diagnostic scheme for patients in outpatient care.",[27,28,29,30],"Autonomic Neuropathy","Ehlers-Danlos Syndrome Hypermobility Type","Small Fiber Neuropathy","Postural Tachycardia Syndrome","RECRUITING","2025-02-03",{"date":34,"type":35},"2025-02-04","ACTUAL",{"date":37,"type":35},"2019-09-15",{"date":39,"type":22},"2029-09-15",{"name":41,"class":42},"RWTH Aachen University","OTHER"]