[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"av-block-2nd-degree-type-1\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:av-block-2nd-degree-type-1":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100620352","efficacy-and-safety-of-micra-av2-transcatheter-pacing-system-100620352",false,"NCT07356505","Efficacy and Safety of Micra AV2 Transcatheter Pacing System","EMAV2","Inclusion Criteria:\n\n1. Voluntary written informed consent of the participant or their legally authorized representative has been obtained prior to any screening procedures\n2. At least 18 years of age at the time of signing the Informed Consent Form (ICF)\n3. Participant will be implanted with a Micra AV2 for an approved indication for use\n4. Participant with a history of any type of high-degree AV block\n5. Participant is willing and able to comply the study protocol\n\nExclusion Criteria:\n\n-1. Subject implanted with a Micra AV2 on a non-permanent basis (e.g. CIED infection) 2. Subject is pregnant (if required by local law, women of child-bearing potential must undergo a pregnancy test within seven days prior to Micra AV2 implant procedure) 3. Subject currently enrolled or planning to participate in a potentially confounding drug or device trial during the study.\n\n4\\. Subject meets any exclusion criteria required by local law (age or other)","ALL","18 Years",{"count":19,"type":20},150,"ESTIMATED","INTERVENTIONAL",[23],"NA","A third generation, Micra AV2 is now available and proposes increased automaticity and improved AV synchrony algorithms based on computing model. The new algorithms permit the delivery of AV synchronous pacing, improving the automatic AV synchrony at faster heart rates between 80-100 bpm with a maximal upper tracking rate limit of 135 bpm (previously 115-120 bpm in the Micra AV1). Micra AV2 presents also a potential extended longevity of 15.6 years (increased by \\> 44% in comparison of Micra AV1). Up to now, no clinical study has evaluated the efficacy and safety of Micra AV2 in a real-world setting.\n\nThe focus of this study is to characterize chronic ambulatory AV synchrony in patients with high degree AV block and normal sinus rhythm implanted with a Micra AV2 as primary objective to evaluate AV synchrony during exercise as secondary objective.",[26,27,28],"AV Block Complete","AV Block-2Nd Degree-Type 1","AV Block",[30,31,32],"leadless pacemaker","Micra AV","AV synchrony","RECRUITING","2026-01-12",{"date":36,"type":37},"2026-01-21","ACTUAL",{"date":34,"type":37},{"date":40,"type":20},"2029-01-31",{"name":42,"class":43},"Universitaire Ziekenhuizen KU Leuven","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":53,"enrollmentInfo":54,"targetDuration":56,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":44},"100528861","cardioneuroablation-for-recurrent-vasovagal-syncope-and-bradyarrhythmias-the-cna-fwrd-registry-100528861","NCT06166277","Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry","Cardioneuroablation for the Management of Patients With Recurrent Vasovagal Syncope and Symptomatic Bradyarrhythmias: The CNA-FWRD Registry","CNA-FWRD","Inclusion Criteria:\n\n* symptomatic vasovagal syncope or symptomatic bradyarrhythmia refractory to behavioral and medical measures\n* age \\\u003C 60 years\n\nExclusion Criteria:\n\n* age \\> 60 years\n* intra-\u002Finfra-Hisian AV block\n* intrinsic sinus node disease\n* history of supraventricular tachycardia\n* history of ventricular tachycardia\n* presence of structural heart disease related\n* prior history of catheter ablation\n* presence of inheritable arrhythmic conditions\n* orthostatic hypotension on HUTT test\n* abnormal thyroid function levels\n* Proven indication for permanent pacemaker implantation","60 Years",{"count":55,"type":20},300,"3 Years","OBSERVATIONAL","The CNA-FWRD Registry is an international prospective observational multicenter registry of patients with symptomatic vasovagal syncope and bradyarrhythmias managed under routine care by medical therapy and radiofrequency catheter ablation of ganglionated plexi or permanent pacemaker implantation.",[60,27,61],"Vasovagal Syncope","Sinus Pause",[63,64,65,66,67,68],"vasovagal syncope","av block","sinus pause","pacemaker","cardioneuroablation","radiofrequency ablation","2025-09-17",{"date":71,"type":37},"2025-09-18",{"date":73,"type":37},"2024-08-01",{"date":75,"type":20},"2027-04-30",{"name":77,"class":43},"Rush University Medical Center"]