[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"av-node-ablation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:av-node-ablation":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100611789","redo-af-randomized-evaluation-of-dual-options-for-af-re-intervention-100611789",false,"NCT07245147","REDO-AF: Randomized Evaluation of Dual Options for AF Re-intervention","REDO-AF","Inclusion Criteria:\n\n* One or more prior left atrial (LA) ablation procedure(s) for AF\n* Symptomatic AF\u002Fatypical atrial flutter\u002Fatrial tachycardia with failure of or intolerance to medical rate or rhythm control therapy, that is detected at \\>2 months post most recent LA ablation procedure\n* Either a LA volume index on any prior echo of \\>= 45ml\u002Fm2 or LA diameter \\>= 50mm OR a HATCH score \\>=2 (where 1 point is given for each for hypertension, Age\\>75, COPD, and 2 points for each of stroke\u002FTIA, or HF (defined as signs or symptoms of pulmonary edema and may include HFrEF or HFpEF)\n* Be considered suitable for both treatment strategies of redo ablation and pacemaker and AV node ablation\n* Willingness to participate, complete the QOL questionnaires and ability to sign informed consent\n\nExclusion Criteria:\n\n* Severe valvular disease defined by echo criteria\n* Myocardial infarction, stroke, or coronary revascularization within the previous 3 months\n* LVEF \\\u003C40% or need for an ICD\n* Life expectancy \\\u003C24 months\n* Lack of capacity to consent","ALL","18 Years",{"count":19,"type":20},16,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this randomized open-label clinical trial is to evaluate two different strategies for the treatment of recurrent atrial fibrillation (AF) after AF ablation. Patients who have symptomatic, drug-refractory recurrence of AF will be randomized to either a redo AF ablation vs conduction system pacing with AV node ablation. Patients will need to have undergone at least 1 prior AF ablation to be considered eligible for the study. The current trial is a vanguard study of 16 patients and will determine the feasibility of enrolment, compare changes in quality of life, and inform the design of the definitive REDO AF trial.",[26,27,28],"Atrial Fibrillation (AF)","AV Node Ablation","Left Bundle Branch Pacing",[30,31,32,33,34,35],"Atrial fibrillation","pace and ablate","AV node ablation","Left bundle branch pacing","LBBP","Redo","NOT_YET_RECRUITING","2025-11-20",{"date":39,"type":40},"2025-11-24","ACTUAL",{"date":42,"type":20},"2025-11",{"date":44,"type":20},"2027-09",{"name":46,"class":47},"Jacqueline Joza","OTHER"]