[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"balance-control\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:balance-control":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100641633","hf-rtms-primed-balance-training-on-corticomotor-excitability-balance-and-gait-in-parkinsons-100641633",false,"NCT07653256","HF-rTMS Primed Balance Training on Corticomotor Excitability, Balance, and Gait in Parkinson's","Effects of High-frequency Repetitive Transcranial Magnetic Stimulation-primed Balance Training on Corticomotor Excitability, Balance, and Gait Performance in Parkinson's Disease","Inclusion Criteria:\n\n* Diagnosed with idiopathic PD\n* Aged between 40-80 years\n* Stable on antiparkinsonian medication ( \\> 3 months)\n* H\\&Y I-III\n* Able to walk continuously for at least 10 minutes\n* The ability to follow commands and instructions\n\nExclusion Criteria:\n\n* Neurological diseases other than PD\n* Severe musculoskeletal, cardiopulmonary disorders\n* MMSE \\\u003C 24\n* Contraindications for TMS\n* Have undergone or are scheduled to undergo neurological surgery during the study participation period","ALL","40 Years","80 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to investigate the effects of repeated transcranial magnetic stimulation combined with modified otago exercise program balance training intervention on motor cortex excitability, balance, and gait performance in patients with Parkinson's disease.",[27,28,29,30,31],"Parkinson's Disease","Corticomotor Excitability","Balance Control","Gait Performance","Motor Symptoms","NOT_YET_RECRUITING","2026-06-11",{"date":35,"type":36},"2026-06-17","ACTUAL",{"date":38,"type":21},"2026-07-01",{"date":40,"type":21},"2028-04-01",{"name":42,"class":43},"Chung Shan Medical University","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":73},"100575380","brain-stimulation-for-foot-sole-sensation-in-older-adults-with-foot-sole-somatosensory-deficits-100575380","NCT06771531","Brain Stimulation for Foot-sole Sensation in Older Adults With Foot-sole Somatosensory Deficits","Cortical Mechanisms and Modulation of Somatosensation in Older Adults With Foot Sole Somatosensory Impairments","BSFS","Inclusion Criteria:\n\n1. Aged ≥65 years.\n2. Self-reported feeling of unsteadiness or difficulty when standing and walking.\n3. Mild-to-moderate foot-sole somatosensory impairment: the ability to perceive 75g monofilament but inability to perceive 10g monofilament.\n\nExclusion Criteria:\n\n1. self-reported inability to stand or walk continuously for one minute without personal assistance (canes or walkers allowed);\n2. history or presence of foot ulceration, amputation, or deformities;\n3. self-reported uncontrolled pain or pain that is associated with mobility disability;\n4. uncontrolled diabetes mellitus;\n5. hospitalization within the past three months due to acute illness, or as the result of a musculoskeletal injury significantly affecting balance;\n6. persistent severe pain of lower extremity when standing or walking;\n7. diagnosis of dementia, Parkinson's disease, or stroke that affects balance;\n8. unstable medical condition;\n9. legal blindness or deafness;\n10. uncontrolled hypertension (i.e., systolic BP \\>180, diastolic BP \\>100 mm Hg, or prescription of ≥3 anti-hypertensive medications);\n11. functionally limiting nephropathy, severe diseases or transplant of the kidney or liver, renal or congestive heart failure;\n12. active cancer treatment;\n13. balance disorders due to past use of chemotherapy or history of Guillain-Barré syndrome;\n14. use of neuro-active or recreational drugs (e.g., sedatives, anti-psychotics), or alcohol abuse, which may affect the brain excitability;\n15. contraindications to MRI or tDCS (e.g., personal or family history of seizures or epilepsy, metallic or electric bio-implants, claustrophobia, brain surgery);\n16. persistent vertigo;\n17. history of Charcot-Marie-Tooth nerve disease.","65 Years",{"count":20,"type":21},[24],"In older adults, diminished sensation of the legs and feet is highly prevalent and causes poor balance and reduced mobility. This type of sensation is not only dependent upon the receptors and nerves in the legs and feet, but also upon a complex central nervous system pathway that includes the cerebral cortex of the brain. This project will use a form of noninvasive brain stimulation called transcranial direct current stimulation (tDCS) to test whether increasing the excitability of the brain networks that process sensory feedback can augment foot sole sensation, balance, and mobility in older adults suffering from mild-to-moderate foot sole sensory impairments.",[57,29,58],"Somatosensory Function","Mobility",[60,61,62],"brain stimulation","balance and mobility","foot-sole somatosensory function","RECRUITING","2026-04-21",{"date":66,"type":36},"2026-04-22",{"date":68,"type":36},"2026-02-26",{"date":70,"type":21},"2026-12-31",{"name":72,"class":43},"Hebrew SeniorLife",1,{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":16,"minAge":83,"maxAge":18,"enrollmentInfo":84,"targetDuration":4,"studyType":86,"phases":4,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":73},"100220122","quantified-balance-measures-during-stance-and-gait-multiple-sclerosis-patients-a-longitudinal-clinical-study-100220122","NCT02142946","Quantified Balance Measures During Stance and Gait: Multiple Sclerosis Patients. A Longitudinal Clinical Study","Quantified Balance Measures During Stance and Gait: Clinical Relevance for Multiple Sclerosis Patients in Comparison to Patients With Inner Ear Balance Problems. A Longitudinal Clinical Study.","MS-Gait","Inclusion Criteria:\n\n* Balance deficits due to inner ear disease or MS\n\nExclusion Criteria:\n\n* Inability to walk without a walking aid",true,"18 Years",{"count":85,"type":21},300,"OBSERVATIONAL","The primary objective of this project is to track changes over time in balance control parameters measured during stance and gait for different groups of multiple sclerosis (MS) patients. Our primary goal is to determine whether these changes in balance control over time predict transitions in MS progression to a more disease affected state, and are different from changes over time for patients with balance deficits due to vestibular sensory disorders. A part of this goal is also to determine whether these changes in balance control are correlated with changes in patients' self-reported deficits and are similar to those changes in balance control of patients with peripheral vestibular loss. The secondary objective is to determine for multiple sclerosis (MS) patients the relationship of their balance parameters to different gait speeds, in order to advise them on, and promote via feedback, safe walking speeds. Fulfilling the first of our objectives would lead to better tracking of MS disease changes over time, earlier quantification of onset of symptoms suggesting a worsening of disease status, and, we assume, greater patient satisfaction knowing that quantification of symptoms fits subjective feelings of balance deficits during stance and gait. Achieving the second objective would lead to improved balance during gait. We aim to carry out these objectives using equipment (SwayStar) which we have proven is sensitive to MS induced balance deficits {2}, but costs far less to operate and maintain than previously used quantification tools. We aim to investigate the balance deficits during gait in different MS patient groups using a multimodal approach with a SwayStar system (analysis of balance during stance and gait in terms of trunk-pelvis movements near the centre of mass) and patient questionnaires.",[29],"2025-04-03",{"date":91,"type":36},"2025-04-06",{"date":93,"type":36},"2018-04-01",{"date":95,"type":21},"2025-12",{"name":97,"class":43},"University Hospital, Basel, Switzerland"]