[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"balance\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:balance":29},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,49,0,25,[9,49,81,111,134,158,190,218,244,273,295,325,343,369,401,424,461,490,518,543,563,595,619,653,682],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100635573","wearable-sensory-prosthesis-to-improve-coordination-walking-and-physical-activity-100635573",false,"NCT07554443","Wearable Sensory Prosthesis to Improve Coordination, Walking, and Physical Activity","Wearable Sensory Prostheses to Improve Neuromuscular Coordination, Walking Function, and Real-World Physical Activity","Inclusion Criteria:\n\n* Be 60 years of age or older\n* Have a diagnosis of PN with plantar sensory loss\n* Demonstrate balance impairment, defined as a Single-Leg Stance time of \\\u003C23 seconds\n* Be able to walk independently for at least 6 minutes without the use of an assistive device (rest breaks permitted)\n* Be willing to use the Walkasins device as recommended\n* Be willing to participate in all aspects of physical activity monitoring and study assessments\n\nExclusion Criteria:\n\n* Under 60 years old\n* Do not have a diagnosis of PN with plantar sensory loss\n* Self-reported acute thrombophlebitis, including deep vein thrombosis\n* Self-reported severe peripheral vascular disease\n* Untreated lymphedema\n* Untreated lesion of any kind, swelling, infection, inflamed area of skin or eruptions on the lower leg near product use\n* Self-reported, untreated fractures in the foot and ankle\n* Other neurological or musculoskeletal conditions that moderately or severely impact walking\n* Use of ankle-foot orthosis for ambulation that prevents donning of Walkasins\n* Weight of more than 300 pounds\n* Inability to perceive vibration from Walkasins Haptic Module\n* Do not demonstrate balance impairments, defined as a Single-Leg Stance time of \\\u003C23 seconds","ALL","60 Years",{"count":20,"type":21},18,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to investigate whether sensory stimulations from a neuroprosthesis device (Walkasins®) can increase physical activity and improve gait quality in persons with peripheral neuropathy (PN). The main question it aims to answer is whether Walkasins enhances habitual activity patterns in adults with peripheral neuropathy.\n\nParticipants will do the following as part of the study:\n\n* Complete a sensation and balance assessment to determine eligibility for the study.\n* Answer questions about their medical history, physical function, balance confidence, and sleep.\n* Perform various balance and walking tasks on three separate occasions. One of the tests involves walking for six minutes without a cane or walker.\n* Wear an activPAL activity monitor for ten days on three separate occasions and return it to the researcher as directed.\n* Wear Walkasins for ten weeks as part of their daily routine. Walkasins consists of two parts: 1) an insole that fits inside the shoe and 2) a strap that secures around the ankle.",[27,28,29,30,31,32],"Peripheral Neuropathy With Type 2 Diabetes","Peripheral Neuropathy Grade 2 or Greater","Balance","Balance Impairment, Gait Disorders, Fatigue","Balance Disorders","Physical Activities",[34,35,31,36],"Peripheral Neuropathy","Walkasins","Physical Activity","RECRUITING","2026-06-22",{"date":40,"type":41},"2026-06-25","ACTUAL",{"date":40,"type":21},{"date":44,"type":21},"2027-12",{"name":46,"class":47},"RxFunction Inc.","INDUSTRY",1,{"id":50,"slug":51,"hasResults":12,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":68,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":48},"100641968","the-effects-of-game-based-exercise-programs-100641968","NCT07660822","THE EFFECTS OF GAME-BASED EXERCISE PROGRAMS","THE EFFECTS OF VIRTUAL REALITY AND VIDEO GAME-BASED EXERCISE PROGRAMS ON PHYSICAL FITNESS AND ATTENTION LEVELS IN HEALTHY ADOLESCENTS","Inclusion Criteria:\n\n* Volunteering to participate in the study\n* Being an adolescent aged 10-18 years\n* Having a score below 4 on the Physical Activity Scale for Adolescents\n\nExclusion Criteria:\n\n* Having any physical disability that would prevent participation in the exercise program\n* Having upper or lower extremity orthopedic disease\n* Having a score above 4 on the Physical Activity Scale for Adolescents",true,"10 Years","18 Years",{"count":60,"type":21},48,[24],"Studies comparing aerobic exercise with virtual reality or video game technologies to traditional games and classical exercise have been conducted in healthy adolescents, but no studies comparing virtual reality and video game technologies have been found. Based on all this, we aimed to investigate the effect of virtual reality and video game-based exercise programs on physical fitness and attention levels in healthy adolescents. The study was planned as a quantitative experimental randomized controlled trial. Healthy individuals aged 10-18 years who meet the inclusion criteria will be evaluated during the dates of the study. Individuals will be divided into 3 groups: a classical physical activity group, a virtual reality group, and a video-based game group. Each program will be implemented for 20-30 minutes, three days a week for eight weeks. The Physical Activity Scale for Adolescents was used to evaluate the physical activity of the individuals, the Multidimensional Body-Self Relationship Scale was used to measure body image, and the Exercise Benefit\u002FBarrier Scale was used to measure exercise perception. To measure attention, balance, and reaction time, the D2 Attention Test, Y-Balance Test, and Nelson's Hand Reaction Test will be administered, respectively. In the virtual reality and video-based game group, the games played by participants will be similar to the physical activities performed in the classic exercise group. One or more games incorporating these physical activities will be selected.",[36,64,65,29,66,67],"Body Image","Exercise Perception","Reaction Time","Attention",[69,70,71],"Healthy adolescent","virtual reality","attention level)","2026-06-16",{"date":38,"type":41},{"date":75,"type":41},"2025-11-15",{"date":77,"type":21},"2026-08-30",{"name":79,"class":80},"Gaziantep Islam Science and Technology University","OTHER",{"id":82,"slug":83,"hasResults":12,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":12,"sex":17,"minAge":89,"maxAge":58,"enrollmentInfo":90,"targetDuration":4,"studyType":92,"phases":4,"briefSummary":93,"conditions":94,"keywords":99,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":48},"100642191","core-stability-functional-capacity-balance-strength-and-fatigue-in-pediatric-demyelinating-diseases-100642191","NCT07654738","Core Stability, Functional Capacity, Balance, Strength, and Fatigue in Pediatric Demyelinating Diseases","Investigation of the Relationship Between Core Stability, Functional Capacity, Balance, Lower Extremity Strength, and Fatigue in Pediatric Demyelinating Diseases","PEDI-CORE","Inclusion Criteria:\n\n* Age between 6 and 18 years\n* Diagnosed with a pediatric demyelinating disease\n* No relapse within the last 3 months\n* No botulinum toxin (Botox) injections within the last 3 months\n* No corticosteroid treatment within the last 3 months\n* Ability to read and write\n\nExclusion Criteria:\n\n* History of concomitant autoimmune diseases\n* Refusal of the patient and\u002For caregiver to participate in the study\n* History of another primary neurological disease\n* Cognitive impairment that limits understanding of instructions and participation in assessments\n* Visual and\u002For hearing impairments that interfere with activities of daily living\n* Presence of additional rheumatological conditions that may interfere with assessments\n* Spasticity grade ≥2 according to the Modified Ashworth Scale in any muscle group","6 Years",{"count":91,"type":21},32,"OBSERVATIONAL","This study aims to evaluate balance ability, core stability, functional capacity, lower extremity muscle strength, and fatigue levels in children diagnosed with central nervous system demyelinating diseases, in order to contribute to the development of evidence-based and individualized rehabilitation strategies.",[95,96,97,29,98],"Demyelinating Diseases of the Central Nervous System","Child","Core Stability","Fatigue",[100,97,29,98],"Pediatric Demyelinating Diseases","NOT_YET_RECRUITING","2026-06-12",{"date":104,"type":41},"2026-06-17",{"date":106,"type":21},"2026-07-30",{"date":108,"type":21},"2028-01-30",{"name":110,"class":80},"Istanbul University - Cerrahpasa",{"id":112,"slug":113,"hasResults":12,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":56,"sex":17,"minAge":58,"maxAge":118,"enrollmentInfo":119,"targetDuration":121,"studyType":92,"phases":4,"briefSummary":122,"conditions":123,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":48},"100642542","spinal-alignment-spinal-mobility-and-balance-in-patients-with-multiple-sclerosis-100642542","NCT07648277","Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis","Relationship Between Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis","Inclusion Criteria:\n\n* Diagnosis of relapsing-remitting multiple sclerosis (RRMS)\n* Aged between 18 and 65 years\n* EDSS score between 0.5 and 4.5\n* Standardized Mini-Mental State Examination score ≥24\n\nExclusion Criteria:\n\n* Receipt of corticosteroid treatment within the previous 4 weeks\n* Presence of any additional neurological disorder\n* Spasticity defined as a Modified Ashworth Scale score ≥3\n* History of surgical intervention involving the lower extremities, spine, or abdominal region","65 Years",{"count":120,"type":21},30,"2 Years","Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system characterized by demyelination and axonal degeneration. Neuromuscular impairments associated with MS, including muscle weakness, spasticity, fatigue, and proprioceptive deficits, may lead to alterations in spinal posture and reduced spinal mobility. These changes can negatively affect trunk control, balance, respiratory function, and functional independence.\n\nAlthough postural abnormalities and mobility limitations have been reported in individuals with MS, the relationship between spinal posture, spinal mobility, and balance remains insufficiently investigated. Therefore, this study aims to examine the associations between spinal posture, spinal mobility, and balance performance in individuals with multiple sclerosis. Improved understanding of these relationships may contribute to the development of targeted rehabilitation interventions aimed at enhancing postural control and functional outcomes in this population. This study further hypothesises that alterations in spinal posture and spinal mobility are associated with impaired balance performance in individuals with multiple sclerosis.",[124,29],"Multiple Sclerosis","2026-06-10",{"date":127,"type":41},"2026-06-15",{"date":129,"type":41},"2026-02-01",{"date":131,"type":21},"2026-06-30",{"name":133,"class":80},"Ankara Yildirim Beyazıt University",{"id":135,"slug":136,"hasResults":12,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":4,"eligibilityCriteria":140,"healthyVolunteers":56,"sex":141,"minAge":18,"maxAge":142,"enrollmentInfo":143,"targetDuration":4,"studyType":92,"phases":4,"briefSummary":144,"conditions":145,"keywords":4,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":151,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":4},"100642517","balance-fall-risk-and-gait-in-women-with-total-knee-arthroplasty-100642517","NCT07650175","Balance, Fall Risk, and Gait in Women With Total Knee Arthroplasty","Investigation of Balance, Fall Risk, Gait Performance, and Quality of Life in Postmenopausal Women Undergoing Total Knee Arthroplasty","Inclusion Criteria:\n\n* Volunteering to participate in the study.\n* Being 60 years of age or older.\n* Having a Mini Mental Test score of 24 or higher.\n* Not having undergone previous arthroplasty surgery on the knee where surgery is planned.\n* Having experienced unilateral TDA.\n* Being a postmenopausal woman\n\nExclusion Criteria:\n\n* Individuals whose vital signs are unstable after surgery, or who develop any major complications such as deep vein thrombosis, pulmonary embolism, wound infection, or prolonged anesthesia side effects.\n* Presence of any neurological, vestibular, visual, cardiopulmonary, auditory, or cognitive deficits that may affect measurements.\n* Individuals diagnosed with diabetes.","FEMALE","85 Years",{"count":120,"type":21},"Total knee arthroplasty (TKA) is a commonly performed surgical procedure aimed at reducing pain, restoring joint function, and improving quality of life, particularly among older women. Despite improvements in pain and functional outcomes following TKA, findings regarding balance, fall risk, and gait performance remain inconsistent. Impairments in these parameters may adversely affect daily activities, independence, and overall quality of life.\n\nUnlike previous studies that have primarily focused on one or two outcomes, this study will comprehensively evaluate balance, fall risk, gait performance, and quality of life in postmenopausal women who have undergone TKA. The findings are expected to provide a more holistic understanding of long-term functional outcomes following TKA and contribute to the planning of rehabilitation programs. Therefore, the aim of this study is to compare balance, fall risk, gait performance, and quality of life between postmenopausal women who have undergone TKA and healthy postmenopausal women.",[146,147,148,29,149,150],"Total Knee Arthroplasty","Postmenopausal Women","Quality of Life (QOL)","Risk of Falling","Walking",{"date":72,"type":41},{"date":153,"type":21},"2026-06-20",{"date":155,"type":21},"2026-07-22",{"name":157,"class":80},"Karabuk University",{"id":159,"slug":160,"hasResults":12,"nctId":161,"briefTitle":162,"officialTitle":163,"acronym":4,"eligibilityCriteria":164,"healthyVolunteers":12,"sex":17,"minAge":165,"maxAge":166,"enrollmentInfo":167,"targetDuration":4,"studyType":22,"phases":169,"briefSummary":170,"conditions":171,"keywords":176,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":182,"lastUpdatePostDateStruct":183,"startDateStruct":185,"completionDateStruct":187,"leadSponsor":188,"locationsCount":4},"100639537","theratogs-effects-on-balance-and-mobility-in-cerebral-palsy-100639537","NCT07618962","TheraTogs Effects on Balance and Mobility in Cerebral Palsy","The Effect of the Dynamic Orthotic Garment TheraTogs on Balance and Functional Mobility of Children and Adolescent With Cerebral Palsy: A Cross-Sectional Clinical Study","Inclusion Criteria\n\n* Diagnosis of unilateral or bilateral spastic Cerebral Palsy\n* GMFCS level I or II\n* MAS level lower than +1\n* Ability to understand and follow instructions\n* Ability to walk without assistive devices\n\nExclusion Criteria\n\n* Use of medications affecting balance\n* Hearing or visual impairments\n* Intellectual disability\n* Botulinum toxin (Botox) injection in the lower limbs within the previous 6 months\n* Severe musculoskeletal deformities\n* Surgery within the previous 6 months\n* Uncontrolled seizures during the previous 6 months","5 Years","15 Years",{"count":168,"type":21},12,[24],"Cerebral Palsy (CP) is the most common cause of childhood disability, with an estimated prevalence of 17 million individuals worldwide. Children and adolescents with CP present impaired postural control and balance, negatively affecting their mobility and functional performance. The use of dynamic orthotic garments may contribute to the improvement of postural control, balance, and functional mobility in children and adolescents with CP.\n\nThe aim of the present study is to investigate the immediate effect of the dynamic orthotic garment TheraTogs on balance and functional mobility in children and adolescents with CP.\n\nIn this cross-sectional pilot study, children and adolescents with CP classified as levels I and II according to the Gross Motor Function Classification System (GMFCS), and with spasticity levels lower than +1 according to the Modified Ashworth Scale, will participate. Balance will be assessed using the Pediatric Balance Scale (PBS), while functional mobility will be evaluated with the Timed Up and Go (TUG) test and the 10 Meter Walk Test (10MWT). Each assessment will be performed twice by each participant, with and without the TheraTogs dynamic orthotic garment, in random order. Statistical analysis will be conducted using SPSS Statistics V29 software, with the level of significance set at p \\\u003C 0.05.",[172,173,174,175],"Cerebral Palsy","THERATOGS","BALANCE","FUCTIONAL MOBILITY",[172,177,178,179,180,181],"children","adolescents","balance","functional mobility","TheraTogs","2026-05-30",{"date":184,"type":41},"2026-06-02",{"date":186,"type":21},"2026-06",{"date":186,"type":21},{"name":189,"class":80},"University of West Attica",{"id":191,"slug":192,"hasResults":12,"nctId":193,"briefTitle":194,"officialTitle":195,"acronym":196,"eligibilityCriteria":197,"healthyVolunteers":12,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":198,"targetDuration":4,"studyType":22,"phases":200,"briefSummary":201,"conditions":202,"keywords":207,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":209,"lastUpdatePostDateStruct":210,"startDateStruct":212,"completionDateStruct":214,"leadSponsor":216,"locationsCount":48},"100638614","the-effects-of-high-intensity-interval-training-on-gait-balance-and-cognitive-functions-in-individuals-with-multiple-sclerosis-100638614","NCT07578740","The Effects of High-Intensity Interval Training on Gait, Balance, and Cognitive Functions in Individuals With Multiple Sclerosis","Investigating the Effects of High-Intensity Interval Training on Gait, Balance, and Cognition in Individuals With Multiple Sclerosis","HIIT-MS","Inclusion Criteria:\n\n* Diagnosed with Multiple Sclerosis by a neurologist (Hacettepe University Hospitals, Neurology Outpatient Clinic)\n* Age 18 years and older\n* EDSS score between 0 and 4\n* Score of 24 or above on the Standardized Mini Mental State Examination\n* No relapse in the past 3 months\n* Medically stable for at least 6 months\n\nExclusion Criteria:\n\n• Any additional cardiopulmonary, neurological, or systemic disease other than MS",{"count":199,"type":21},40,[24],"This study aims to comparatively investigate the effects of low-volume High-Intensity Interval Training (HIIT) versus Moderate-Intensity Continuous Training (MICT) on gait, balance, cognitive functions, and neurovascular biomarkers (BDNF, VEGF) in individuals with Multiple Sclerosis (MS). This randomized controlled trial will be conducted at Hacettepe University, Faculty of Physical Therapy and Rehabilitation.",[124,203,204,29,205,206],"High-intensity Interval Training","Gait","Cognition","Biomarkers",[208],"Multiple Sclerosis, High-Intensity Interval Training, HIIT, Gait, Balance, Cognition, BDNF, VEGF, Randomized Controlled Trial","2026-05-18",{"date":211,"type":41},"2026-05-20",{"date":213,"type":21},"2026-07",{"date":215,"type":21},"2028-06",{"name":217,"class":80},"Hacettepe University",{"id":219,"slug":220,"hasResults":12,"nctId":221,"briefTitle":222,"officialTitle":222,"acronym":4,"eligibilityCriteria":223,"healthyVolunteers":12,"sex":17,"minAge":58,"maxAge":224,"enrollmentInfo":225,"targetDuration":4,"studyType":22,"phases":227,"briefSummary":228,"conditions":229,"keywords":231,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":236,"lastUpdatePostDateStruct":237,"startDateStruct":239,"completionDateStruct":241,"leadSponsor":242,"locationsCount":4},"100638932","effects-of-a-combined-repetitive-transcranial-magnetic-stimulation-and-physical-therapy-protocol-on-motor-function-balance-and-quality-of-life-in-chronic-post-stroke-hemiplegia-a-case-series-100638932","NCT07597746","\"Effects of a Combined Repetitive Transcranial Magnetic Stimulation and Physical Therapy Protocol on Motor Function, Balance, and Quality of Life in Chronic Post-Stroke Hemiplegia: A Case Series\"","Inclusion Criteria:\n\n* Diagnosis of first-ever unilateral ischemic or hemorrhagic stroke confirmed by neuroimaging (CT or MRI)\n* Chronic post-stroke hemiplegia (≥ 6 months since stroke onset)\n* Moderate to severe motor impairment of the affected lower limb (FMA-LE score between 10 and 28 points)\n* Age between 18 and 75 years\n* Medically stable and able to participate in a rehabilitation program\n* Ability to understand study procedures and provide written informed consent\n* No contraindications to repetitive transcranial magnetic stimulation (rTMS), according to current safety guidelines.\n\nExclusion Criteria:\n\n* History of epilepsy or seizures\n* Presence of pacemakers, cochlear implants, intracranial metallic implants, or other contraindications to rTMS\n* Severe cognitive impairment or communication deficits preventing participation\n* Progressive neurological disorders or unstable medical conditions\n* Participation in other experimental neurorehabilitation interventions during the study period\n* Any condition judged by investigators to compromise safety or data valid","75 Years",{"count":226,"type":21},20,[24],"Chronic post-stroke hemiplegia frequently results in persistent motor deficits, impaired balance, and reduced quality of life. Conventional physical therapy is fundamental for functional recovery; however, motor improvement often plateaus during the chronic phase. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation technique that has shown potential to enhance motor recovery by modulating cortical excitability and promoting neuroplasticity.\n\nThis case series aims to investigate the effects of a combined protocol of repetitive transcranial magnetic stimulation and conventional physical therapy on motor function, balance, and quality of life in individuals with chronic post-stroke hemiplegia. Participants will undergo rTMS applied to the motor cortex in conjunction with a structured physical therapy program. Clinical outcomes will be assessed before and after the intervention to explore feasibility, safety, and potential functional benefits of the combined approach.",[230,29],"Chronic Stroke",[232,233,234,179,235],"repetitive transcraneal magnetic stimulation","chronic stroke","motor recovery","physical therapy","2026-05-13",{"date":238,"type":41},"2026-05-19",{"date":240,"type":21},"2026-06-05",{"date":77,"type":21},{"name":243,"class":80},"Sierra Varona SL",{"id":245,"slug":246,"hasResults":12,"nctId":247,"briefTitle":248,"officialTitle":248,"acronym":4,"eligibilityCriteria":249,"healthyVolunteers":12,"sex":17,"minAge":250,"maxAge":142,"enrollmentInfo":251,"targetDuration":4,"studyType":22,"phases":253,"briefSummary":254,"conditions":255,"keywords":257,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":265,"lastUpdatePostDateStruct":266,"startDateStruct":267,"completionDateStruct":269,"leadSponsor":271,"locationsCount":48},"100638095","effects-of-kinect-based-exergaming-versus-wii-fit-training-on-balance-and-fall-risk-among-healthy-older-adults-100638095","NCT07596225","Effects of Kinect-Based Exergaming Versus Wii Fit Training on Balance and Fall Risk Among Healthy Older Adults","Inclusion Criteria:\n\n* Older adults aged ≥55, community-dwelling, with a BBS score between 21-50, including both mild to moderate Risk falls\n* Able to stand without assistive devices\n* Cognitively able to follow instructions, with a MoCA score ≥ 22\n* Both Genders: Males and females\n\nExclusion Criteria:\n\n* History of Neurological disorders affecting balance (e.g., Parkinson's disease, stroke)\n* Acute Vestibular disorders\u002FMajor Musculoskeletal impairments (e.g., Arthritis)\n* Participation in other balance training programs within the past 6 months\n* Any condition posing a safety risk (e.g., severe osteoporosis, uncontrolled hypertension","55 Years",{"count":252,"type":21},46,[24],"Study, titled Effects of Kinect-Based Exergaming versus Wii Fit on Balance and Fall Risk among Healthy Older Adults, is a randomized controlled trial comparing the balance training effects of Xbox Kinect and Wii Fit.\n\nAfter obtaining informed consent, 46 healthy older adults will be randomly allocated (1:1) using sealed envelopes to a 6-week training program in either group. Static, Dynamic, and Anticipatory balance will be assessed at baseline and post-intervention using the Biodex Balance System for objective comparison.",[29,256],"Fall Risk",[258,259,260,261,262,70,263,264],"Postural Balance","Postural Control","Accidental Falls","Risk factors","Aged","video games","rehabilitation","2026-05-12",{"date":238,"type":41},{"date":268,"type":21},"2026-05-05",{"date":270,"type":21},"2026-07-15",{"name":272,"class":80},"Foundation University Islamabad",{"id":274,"slug":275,"hasResults":12,"nctId":276,"briefTitle":277,"officialTitle":278,"acronym":279,"eligibilityCriteria":280,"healthyVolunteers":12,"sex":17,"minAge":118,"maxAge":4,"enrollmentInfo":281,"targetDuration":4,"studyType":92,"phases":4,"briefSummary":283,"conditions":284,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":286,"lastUpdatePostDateStruct":287,"startDateStruct":289,"completionDateStruct":291,"leadSponsor":293,"locationsCount":48},"100639177","figure-of-8-walk-test-in-individuals-with-motoric-cognitive-risk-syndrome-100639177","NCT07586553","Figure-of-8 Walk Test in Individuals With Motoric Cognitive Risk Syndrome","Validity and Reliability of the Figure-of-8 Walk Test (8FWT) in Individuals With Motoric Cognitive Risk Syndrome","8FWT-MCR","Inclusion Criteria:\n\nAged 65 years or older Presence of subjective cognitive complaints Gait speed ≤ 0.8 m\u002Fs (4-meter walk test) Able to walk independently without assistive devices No clinical diagnosis of dementia Able to understand and follow test instructions\n\nExclusion Criteria:\n\nMini-Mental State Examination (MMSE) score \\\u003C 24 Neurological diseases affecting gait (e.g., stroke, Parkinson's disease, multiple sclerosis) Severe musculoskeletal conditions affecting walking Lower extremity surgery within the last 6 months Severe visual or hearing impairment that interferes with testing Dependence on assistive walking devices",{"count":282,"type":21},52,"This observational study aims to investigate the validity and reliability of the Figure-of-8 Walk Test (8FWT) in individuals with Motoric Cognitive Risk Syndrome (MCRS). The study will evaluate test-retest reliability, measurement error (SEM, MDC), and construct validity by examining the relationship between 8FWT performance and functional mobility measures. The findings are expected to provide evidence for the clinical applicability of 8FWT in assessing dynamic balance, gait performance, and cognitive-motor interaction in older adults.",[285,204,29],"Motoric Cognitive Risk Syndrome","2026-05-07",{"date":288,"type":41},"2026-05-14",{"date":290,"type":41},"2026-04-07",{"date":292,"type":21},"2026-07-08",{"name":294,"class":80},"Balikesir University",{"id":296,"slug":297,"hasResults":12,"nctId":298,"briefTitle":299,"officialTitle":300,"acronym":4,"eligibilityCriteria":301,"healthyVolunteers":12,"sex":17,"minAge":58,"maxAge":302,"enrollmentInfo":303,"targetDuration":4,"studyType":22,"phases":305,"briefSummary":306,"conditions":307,"keywords":312,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":268,"lastUpdatePostDateStruct":317,"startDateStruct":319,"completionDateStruct":321,"leadSponsor":323,"locationsCount":48},"100640667","effectiveness-of-dance-therapy-in-stroke-patients-100640667","NCT07578493","Effectiveness of Dance Therapy in Stroke Patients.","Effectiveness of Proprioceptive Neuromuscular Facilitation-based Dance Therapy for Patients With Chronic Stroke.","Inclusion Criteria:\n\n* Chronic hemiparesis (≥ 6 months post-stroke).\n* Ability to maintain independent standing or with minimal assistance.\n* Clinical stability to perform moderate physical exercise.\n* Sufficient understanding to follow simple instructions.\n\nExclusion Criteria:\n\n* Severe aphasia or other cognitive disorders that limit comprehension.\n* Behavioral disorders that hinder group participation.\n* Severe musculoskeletal disorders or concomitant neurological conditions.","80 Years",{"count":304,"type":21},16,[24],"Hemiparesis following a stroke is associated with persistent deficits in postural control, balance, and social participation, especially in the chronic phase. Dance therapy, as a multisensory intervention based on movement, music, and body expression, could promote sensorimotor integration and improve postural stability, complementing conventional physiotherapy. The primary objective of this pilot study is to evaluate the effect of a therapeutic dance program on postural control in individuals with chronic hemiparesis. A secondary objective is to analyze changes in functional balance and gait, as well as subjective satisfaction with the therapy. A controlled study with two parallel groups will be conducted. Sixteen participants with chronic hemiparesis will be recruited (n=8 experimental group; n=8 control group). Both groups will receive standard physiotherapy, but the experimental group will also receive an 8-week therapeutic dance program, with one 30-minute session per week to complement their usual therapy. Pre- and post-intervention assessments will be performed. ThThe experimental group is expected to show a significantly greater improvement in posturographic and clinical parameters compared to the control group. The results could support the implementation of dance therapy as a complementary intervention in community neurorehabilitation programs.",[29,308,309,310,311],"Gait Analysis","Thermography","Range of Motion, Articular","Muscular Strength",[313,314,315,204,316],"Dance Therapy","Stroke","Postural balance","Physical Therapy Modalities",{"date":318,"type":41},"2026-05-11",{"date":320,"type":21},"2026-05-15",{"date":322,"type":21},"2026-11-30",{"name":324,"class":80},"University of Salamanca",{"id":326,"slug":327,"hasResults":12,"nctId":328,"briefTitle":329,"officialTitle":330,"acronym":4,"eligibilityCriteria":331,"healthyVolunteers":12,"sex":17,"minAge":118,"maxAge":4,"enrollmentInfo":332,"targetDuration":4,"studyType":92,"phases":4,"briefSummary":334,"conditions":335,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":337,"lastUpdatePostDateStruct":338,"startDateStruct":339,"completionDateStruct":341,"leadSponsor":342,"locationsCount":48},"100636998","dual-task-effects-on-gait-and-balance-in-mcrs-100636998","NCT07572968","Dual-Task Effects on Gait and Balance in MCRS","Effects of Cognitive Load on Gait and Balance Performance in Individuals With Motoric Cognitive Risk Syndrome: A Dual-Task Analysis","Inclusion Criteria:\n\nAge ≥ 65 years Subjective cognitive complaints Slow gait speed No dementia diagnosis\n\nExclusion Criteria:\n\nSevere visual\u002Fhearing impairment Neurological diseases (stroke, Parkinson) Acute orthopedic conditions affecting walking",{"count":333,"type":21},35,"This study aims to investigate the effects of cognitive load on gait and balance performance in individuals with Motoric Cognitive Risk Syndrome (MCRS). Participants will perform Timed Up and Go (TUG) and tandem walking tests under single-task and dual-task conditions. The study evaluates cognitive-motor interference and dual-task cost to better understand early markers of cognitive decline and fall risk.",[285,336,204,29],"Dual-Task Performance","2026-05-01",{"date":286,"type":41},{"date":340,"type":41},"2026-04-15",{"date":270,"type":21},{"name":294,"class":80},{"id":344,"slug":345,"hasResults":12,"nctId":346,"briefTitle":347,"officialTitle":348,"acronym":4,"eligibilityCriteria":349,"healthyVolunteers":12,"sex":17,"minAge":350,"maxAge":224,"enrollmentInfo":351,"targetDuration":4,"studyType":22,"phases":352,"briefSummary":353,"conditions":354,"keywords":357,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":360,"lastUpdatePostDateStruct":361,"startDateStruct":363,"completionDateStruct":365,"leadSponsor":367,"locationsCount":48},"100635252","body-weight-supported-and-virtual-reality-gait-training-in-stroke-patients-100635252","NCT07550270","Body Weight-Supported and Virtual Reality Gait Training in Stroke Patients","A Comparative Evaluation of the Effectiveness of Body Weight-Supported Forward and Backward Gait Training Versus Virtual Reality-Assisted Gait Training in Patients With Stroke","Inclusion Criteria:\n\n* Patients experiencing their first-ever stroke\n* Patients with a post-stroke duration of more than 2 weeks\n* Patients with plantar flexor muscle spasticity of the lower extremity less than grade 3 according to the Modified Ashworth Scale (MAS)\n* Patients with a Brunnstrom stage of the lower extremity greater than 2\n* Patients who are able to stand independently or under supervision for at least 2 minutes for standing assessments\n* Patients who are able to walk at least 10 meters independently or under supervision, with or without an assistive device, for walking assessments\n* Patients with sufficient cognitive function to understand study instructions (Mini-Mental State Examination \\[MMSE\\] score \\> 23)\n* Patients with stable medical and psychological conditions\n* Patients who are willing to participate in the study\n\nExclusion Criteria:\n\n* Patients with bilateral hemispheric lesions\n* Patients with severe cardiovascular or musculoskeletal conditions that prevent walking (e.g., fixed ankle contracture)\n* Patients using a permanent urinary catheter, or those with pressure ulcers or urinary and\u002For fecal incontinence\n* Patients with unilateral neglect\n* Patients with neurological conditions other than stroke that may affect balance performance (e.g., Parkinson's disease, epilepsy, meningitis, cerebellar disorders, vertigo, dizziness, polyneuropathy) or musculoskeletal disorders (e.g., severe low back pain, knee disorders)\n* Patients with severe visual, hearing, or speech impairments","45 Years",{"count":120,"type":21},[24],"The aim of this study is to compare the effects of body weight-supported gait training that includes virtual reality-assisted dual-task applications with body weight-supported forward and backward gait training on functional capacity, gait parameters (such as step length, gait speed, and balance), cognitive functions and psychological status in patients with stroke. The findings of this study are expected to contribute to the development of more effective rehabilitation strategies for improving mobility in patients with stroke",[314,355,29,356],"Walking Impairment","Gait Training",[358,359],"stroke","gait training","2026-04-19",{"date":362,"type":41},"2026-04-24",{"date":364,"type":41},"2026-03-26",{"date":366,"type":21},"2026-12",{"name":368,"class":80},"Gaziler Physical Medicine and Rehabilitation Education and Research Hospital",{"id":370,"slug":371,"hasResults":12,"nctId":372,"briefTitle":373,"officialTitle":374,"acronym":375,"eligibilityCriteria":376,"healthyVolunteers":12,"sex":141,"minAge":377,"maxAge":378,"enrollmentInfo":379,"targetDuration":4,"studyType":22,"phases":381,"briefSummary":382,"conditions":383,"keywords":389,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":392,"lastUpdatePostDateStruct":393,"startDateStruct":395,"completionDateStruct":397,"leadSponsor":399,"locationsCount":4},"100635050","virtual-reality-training-using-wii-fit-in-children-with-cerebral-palsy-100635050","NCT07547644","Virtual Reality Training Using Wii Fit in Children With Cerebral Palsy","EFFECTS OF VIRTUAL REALITY TRAINING USING WII FIT ON BALANCE, GROSS MOTOR FUNCTION, AND AGILITY IN CHILDREN WITH CEREBRAL PALSY -A RANDOMIZED CONTROLLED TRIAL","VR in CP","Inclusion Criteria:\n\n* ● Children aged 7 to 14 years\n\n  * Diagnosed cases of spastic diplegic CP, characterized by bilateral lower limb involvement\n  * Classified under GMFCS levels I to II.\n  * Having mild to moderate spasticity on Modified Ashworth Scale (MAS) scores ranging from 1, +1 or 2\n  * Mild level intellectual disability according to their health records\n  * Medically stable with no acute illness or uncontrolled comorbidities\n  * No major changes in medication or therapy planned during the study period.\n\nExclusion Criteria:\n\n* ● Orthopedic surgery or botulinum toxin injections in the past 16 months\n\n  * Hearing or visual impaired .\n  * Uncontrolled epilepsy or seizures\n  * Severe attention deficits or psychological issues interfering with task engagement such as attention deficit hyperactivity disorder (ADHD), Autism Spectrum Disorder (ASD) will be excluded from the study .","7 Years","14 Years",{"count":380,"type":21},56,[24],"The goal of this clinical trial is to determine whether virtual reality (VR) training using the Nintendo Wii Fit can improve balance, gross motor function, and agility in children aged 7-14 years with spastic cerebral palsy (GMFCS Levels I-II). The main questions it aims to answer are:\n\nDoes Wii Fit-based VR training improve balance more than conventional physiotherapy?\n\nDoes VR training enhance gross motor skills such as standing, walking, running, and jumping?\n\nDoes VR training improve agility in children with cerebral palsy?\n\nDoes VR training increase enjoyment and engagement during therapy?\n\nResearchers will compare Wii Fit-based VR training with conventional physiotherapy to determine which approach leads to greater improvements in motor function.\n\nParticipants will:\n\nAttend 18 sessions over 6 weeks (3 sessions per week).\n\nPerform either VR-based exercises using the Wii Fit Balance Board or traditional physiotherapy exercises.\n\nComplete pre- and post-intervention assessments using the Pediatric Balance Scale, GMFM-88 (domains D and E), BOT-2 agility subtest, and the PACES enjoyment scale.\n\nThis study aims to explore a fun, cost-effective, and engaging rehabilitation strategy that may improve functional independence and overall quality of life for children with cerebral palsy.",[384,385,29,386,387,388],"Cerebral Palsy (CP)","Virtual Reality","Gross Motor Function Classification System (GMFCS) Level I,II","Gross Motor Functions","Agility",[390,70,179,391],"cerebral palsy","GMFM","2026-04-16",{"date":394,"type":41},"2026-04-23",{"date":396,"type":21},"2026-04-25",{"date":398,"type":21},"2026-08-15",{"name":400,"class":80},"Ziauddin University",{"id":402,"slug":403,"hasResults":12,"nctId":404,"briefTitle":405,"officialTitle":405,"acronym":4,"eligibilityCriteria":406,"healthyVolunteers":12,"sex":17,"minAge":58,"maxAge":18,"enrollmentInfo":407,"targetDuration":4,"studyType":92,"phases":4,"briefSummary":408,"conditions":409,"keywords":411,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":416,"lastUpdatePostDateStruct":417,"startDateStruct":419,"completionDateStruct":420,"leadSponsor":422,"locationsCount":4},"100632603","loss-of-balance-experienced-by-industrial-workers-due-to-hearing-problems-100632603","NCT07515833","Loss of Balance Experienced by Industrial Workers Due to Hearing Problems","Inclusion Criteria:\n\n* Employment in industrial or heavy industrial settings\n* Age between 18 and 60 years\n* Presence of hearing problems diagnosed prior to or after starting industrial work\n\nExclusion Criteria:\n\n* Employment in office-based industrial positions\n* Working duration of less than one year",{"count":333,"type":21},"This study will investigate the balance performance and balance-related activities of daily living in 35 industrial workers with hearing problems exposed to occupational noise, using the Berg Balance Scale and the Vestibular Disorders Activities of Daily Living Scale. The research aims to determine whether there is a statistically significant association between hearing problems, balance performance, and daily noise exposure duration. It is hypothesized that while hearing problems related to occupational noise exposure may exist, they may not be directly associated with clinically significant balance impairment, potentially remaining at a tolerable level in daily life. Furthermore, the correlation between Berg Balance Scale and daily living activity scores will be evaluated to understand the functional impact of balance on these workers.",[29,410],"Hearing Problems",[179,412,413,414,415],"vestibular system","industrial workers","occupational noise","Hearing problems","2026-04-08",{"date":418,"type":41},"2026-04-13",{"date":337,"type":21},{"date":421,"type":21},"2027-01-01",{"name":423,"class":80},"Yeditepe University",{"id":425,"slug":426,"hasResults":12,"nctId":427,"briefTitle":428,"officialTitle":429,"acronym":430,"eligibilityCriteria":431,"healthyVolunteers":12,"sex":17,"minAge":432,"maxAge":18,"enrollmentInfo":433,"targetDuration":4,"studyType":22,"phases":434,"briefSummary":435,"conditions":436,"keywords":441,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":452,"lastUpdatePostDateStruct":453,"startDateStruct":455,"completionDateStruct":457,"leadSponsor":459,"locationsCount":4},"100632041","whole-body-vibration-on-balance-risk-of-falling-and-quality-of-life-in-chemotherapy-induced-peripheral-neuropathy-100632041","NCT07508527","Whole-Body Vibration on Balance, Risk of Falling and Quality of Life in Chemotherapy-Induced Peripheral Neuropathy","Effect of Whole Body Vibration on Balance, Risk of Falling, and Quality of Life in Patients With Chemotherapy Induced Peripheral Neuropathy","WBV\u002FQOL\u002FCIPN","Inclusion Criteria:\n\n* 30 patients diagnosed with chemotherapy-induced peripheral neuropathy from both genders.\n* Their ages will range from 30-60 years old.\n* All patients included in this study will be on chemotherapy from at least one cycle as a treatment of malignant tumor.\n* The patients will be mild to moderate neuropathy according to mTNS.\n* They were medically stable.\n\nExclusion Criteria:\n\n* History of other types of neuropathies (i.e., hereditry peripheral neuropathy associated with nutritional agents and paraneoplastic syndrome-related neuropathy…etc).\n* Unstable medical condition during chemotherapy\n* Patients who are starting new therapy or dose modification during study period\n* Morbid obesity body mass index \\>40%\n* History of non-surgically repaired nerve compression injuries such as carpal tunnel, brachial plexopathy, spinal stenosis, and spinal nerve root compression\n* History of central nervous system primary or metastatic malignancy.","30 Years",{"count":120,"type":21},[24],"The goal of this clinical trial is to evaluate the efficacy of Whole-body vibration in improving postural control, risk of falling, and quality of life in patients with chemotherapy-induced peripheral neuropathy. The main questions it aims to answer are:\n\nDoes Whole-body vibration have a significant effect on postural control, risk of falling, and quality of life in patients with chemotherapy-induced peripheral neuropathy?\n\nResearchers will compare whole body vibration in addition to traditional exercise to traditional exercise alone to see if Whole-body vibration have a significant effect on postural control, risk of falling, and quality of life in patients with chemotherapy-induced peripheral neuropathy.\n\nParticipants will:\n\n* age between 30-60 years old.\n* be on chemotherapy for at least one cycle as a treatment of malignant tumors with peripheral neuropathy.\n* have mild to moderate neuropathy according to mTNS.\n* be assigned randomly into two equal groups (control group (A) and study group (B)).\n* Take three sessions per week for eight weeks.\n* The control group (A) will be treated by selected physical therapy treatment (Strength resistive training, Stretching \\& flexibility, Balance training)\n* The study group (B) will be treated with selected physical therapy treatment in addition to whole-body vibration therapy.",[437,438,439,29,440],"Whole Body Vibration","Chemotherapy Induced Peripheral Neuropathy (CIPN)","Fall Risk, Fall Prevention","Quality of Life",[442,443,444,445,29,446,447,448,449,450,451],"WBV","Whole body vibration","CIPN","Chemotherapy induced peripheral neuropathy","Risk of fall","falling","postural control","fall","QOL","Quality of life","2026-03-31",{"date":454,"type":41},"2026-04-02",{"date":456,"type":21},"2026-04",{"date":458,"type":21},"2027-06",{"name":460,"class":80},"Cairo University",{"id":462,"slug":463,"hasResults":12,"nctId":464,"briefTitle":465,"officialTitle":466,"acronym":467,"eligibilityCriteria":468,"healthyVolunteers":12,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":469,"targetDuration":4,"studyType":22,"phases":471,"briefSummary":472,"conditions":473,"keywords":478,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":482,"lastUpdatePostDateStruct":483,"startDateStruct":484,"completionDateStruct":486,"leadSponsor":488,"locationsCount":4},"100631702","the-effect-of-remotely-delivered-pilates-on-physical--and-psychological-outcomes-in-individuals-with-multiple-sclerosis-100631702","NCT07504120","The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis","Does Remotely Delivered Pilates Influence Physical and Psychological Outcomes in Individuals With Multiple Sclerosis?","MS","Inclusion Criteria:\n\n* Age 18 years or older\n* Self-reported diagnosis of multiple sclerosis by a neurologist\n* Relapse-free for the past 30 days before screening\n* Able to speak and read English as the primary language\n* Access to the internet and e-mail,\n* Ability to use Zoom, and willingness to complete testing sessions and questionnaires\n* Ambulatory without an assistive device (for example, cane)\n* Low to moderate disability, defined as a score of 0-4 on the Patient-Determined Disease Steps (PDDS)\n* Insufficiently active, defined as a score \\\u003C 14 on the Godin Leisure-Time Exercise Questionnaire-Health Contribution Score (GLTEQ-HCS)\n* Adequate visual ability and literacy to read materials printed in 14-point font\n* Currently treated with a disease-modifying therapy\n\nExclusion Criteria:\n\n* Pregnant\n* Elevated risk for strenuous or maximal exercise, defined as more than one \"Yes\" response on the Physical Activity Readiness Questionnaire (PAR-Q) during screening",{"count":470,"type":21},50,[24],"Objectives Objective 1: To determine the effects of a 16-week remotely delivered Pilates intervention on walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS.\n\nObjective 2: To examine the impact of a 16-week remotely delivered Pilates intervention on depression \\& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS.\n\nAim Aim 1: To assess whether the 16-week remotely delivered Pilates intervention significantly improves walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS Aim 2: To investigate whether the 16-week remotely delivered Pilates intervention significantly improves depression \\& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS.\n\nHypothesis Hypothesis 1: The 16-week remotely delivered Pilates intervention will significantly improve walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS.\n\nHypothesis 2: Participants receiving the 16-week remotely delivered Pilates intervention will demonstrate significantly greater improvements in depression \\& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS.",[124,474,150,29,475,476,440,477,205,98],"Pilates Exercise","Fatigue in Multiple Sclerosis","Pain Management","Depression",[479,480,98,205,451,150,477,29,481],"multiple sclerosis","Pilates","Pain","2026-03-25",{"date":452,"type":41},{"date":485,"type":21},"2026-06-01",{"date":487,"type":21},"2027-12-01",{"name":489,"class":80},"University of Illinois at Chicago",{"id":491,"slug":492,"hasResults":12,"nctId":493,"briefTitle":494,"officialTitle":495,"acronym":4,"eligibilityCriteria":496,"healthyVolunteers":56,"sex":141,"minAge":18,"maxAge":497,"enrollmentInfo":498,"targetDuration":4,"studyType":22,"phases":499,"briefSummary":500,"conditions":501,"keywords":506,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":510,"lastUpdatePostDateStruct":511,"startDateStruct":513,"completionDateStruct":515,"leadSponsor":516,"locationsCount":48},"100626282","video-game-intervention-in-older-adults-100626282","NCT07433608","Video Game Intervention In Older Adults","The Effects Of A Video-Based Game Intervention On Cognitive, Physical And Psychosocial Outcomes In Older Adults","Inclusion Criteria:\n\nAge 60 years or older A score of 24 or higher on the Mini Mental State Examination (MMSE) Ability to understand and follow verbal instructions Willingness to participate voluntarily\n\nExclusion Criteria:\n\nPresence of a neurological, orthopedic, or psychiatric diagnosis Medical contraindications to exercise Diagnosis of dementia Acute orthopedic injury Visual or hearing impairment that would interfere with participation Inability to attend sessions regularly","69 Years",{"count":91,"type":21},[24],"The purpose of this clinical trial is to investigate the effects of a rehabilitative game-based intervention on self-efficacy, balance, and visual-motor integration in individuals aged 60 years and older.\n\nThe primary research questions are:\n\nDoes the rehabilitative game-based intervention improve balance and visual-motor integration? Does the rehabilitative game-based intervention improve self-efficacy levels?\n\nResearchers will compare a rehabilitative game intervention group with a control group. Participants will complete baseline and post-intervention assessments. Individuals in the intervention group will participate in rehabilitative game sessions twice per week for 6 weeks, while the control group will not receive any intervention.",[502,503,29,504,505],"Healhty","Aging","Self Efficacy","Visual Motor Integration",[385,507,508,29,509],"Visual-Motor Integration","Older Adults","Self-Efficacy","2026-03-03",{"date":512,"type":41},"2026-03-06",{"date":514,"type":41},"2026-02-17",{"date":290,"type":21},{"name":517,"class":80},"Biruni University",{"id":519,"slug":520,"hasResults":12,"nctId":521,"briefTitle":522,"officialTitle":522,"acronym":4,"eligibilityCriteria":523,"healthyVolunteers":56,"sex":17,"minAge":58,"maxAge":524,"enrollmentInfo":525,"targetDuration":4,"studyType":22,"phases":527,"briefSummary":529,"conditions":530,"keywords":531,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":534,"lastUpdatePostDateStruct":535,"startDateStruct":537,"completionDateStruct":539,"leadSponsor":541,"locationsCount":48},"100577916","early-phase-1-intermittent-visual-perturbations-to-enhance-balance-training-100577916","NCT06804512","Intermittent Visual Perturbations to Enhance Balance Training","Inclusion Criteria:\n\n* Ages 18-30 years, or 65-89 years.\n* Ability to walk independently for 10 minutes continuously.\n* Willingness to be randomized to any experimental group and to participate in all aspects of study assessment and intervention\n\nExclusion Criteria:\n\n-Major cognitive disorder that interferes with independence, based on affirmative response (always\u002Fusually\u002Fsometimes) to the following question: \"As a result of confusion or memory loss, how often do you need assistance with day-to-day activities such as cooking, cleaning, taking medications, driving, or paying bills? Would you say it is 1) Always; 2) Usually; 3) Sometimes; 4) Rarely; or 5) Never\".\n\n* Current or recent (within 6 months) lower limb musculoskeletal injury that causes pain during walking or limits walking ability.\n* History of neurological injury or disability (including spinal cord injury, stroke, Parkinson's disease, or multiple sclerosis).\n* Difficulty communicating with study personnel.\n* Current enrollment in any other clinical trial.\n* Low vision that cannot be corrected by wearing contact lens. Low vision will be operationally defined as visual acuity less than 20\u002F70 on standard eye chart, or difficulty perform complex walking tasks due to visual conditions affecting accurate navigation around and over obstacles (self-reported or observed by examiner). The goggles to be used in the study do not permit eyeglasses while using them.\n* Illiterate or non-English speaking, due to the likelihood of difficulties following protocol instructions.","89 Years",{"count":526,"type":21},540,[528],"EARLY_PHASE1","The purpose of this research study is to determine if intermittent visual perturbations can improve balance training. The investigators will quantify differences in body movement, muscle activity, and beam walking performance during and after practice walking on a balance beam that is 1\" high. The investigators will ask the participants to come to the laboratory twice (2 sessions). The first session will not last more than 3 hours. The second session will not last more than 1 hour and will be two weeks after the first session. In total, the maximum amount of time the participant would be asked to participate is 4 hours.",[29],[532,533],"walking balance","gait","2026-02-09",{"date":536,"type":41},"2026-02-10",{"date":538,"type":41},"2024-08-20",{"date":540,"type":21},"2029-02-28",{"name":542,"class":80},"University of Florida",{"id":544,"slug":545,"hasResults":12,"nctId":546,"briefTitle":547,"officialTitle":548,"acronym":4,"eligibilityCriteria":549,"healthyVolunteers":56,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":550,"targetDuration":4,"studyType":22,"phases":551,"briefSummary":552,"conditions":553,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":555,"lastUpdatePostDateStruct":556,"startDateStruct":558,"completionDateStruct":560,"leadSponsor":561,"locationsCount":48},"100618987","the-acute-effects-of-core-stabilization-exercises-on-balance-and-upper-extremity-functional-performance-in-archers-100618987","NCT07338760","The Acute Effects of Core Stabilization Exercises on Balance and Upper Extremity Functional Performance in Archers","Acute Effect of Core Stabilization Exercises Among Archers","Inclusion Criteria:\n\n* Have been involved in licensed archery for at least 1 year\n\n  * Be willing to participate in the program (both the athlete and their parent\u002Fguardian)\n  * Be an athlete without any illness or disability that prevents participation in sports (as determined by a current medical report submitted to the club for licensing purposes)\n  * Be able to read and write\n\nExclusion Criteria:\n\n* ● Those with diagnosed mental or cognitive problems\n\n  * Those who have undergone orthopedic surgery or received intra-articular steroid treatment within the last 6 months\n  * Those with a diagnosed medical condition that could affect balance and shooting performance\n  * Those with instability issues and associated joint movement restrictions\n  * Those with acute muscle spasms and pain complaints\n  * Those using painkillers, sedatives, alcohol, etc., or any other medication or substance that may affect shooting performance\n  * Those with any diagnosis of injury related to the musculoskeletal system\n  * Those actively involved in another sport besides archery",{"count":120,"type":21},[24],"This randomized controlled study aims to investigate the acute effects of a single session of core stabilization exercises on balance and upper extremity functional performance in competitive archers. Core stability is essential for postural control, neuromuscular coordination, and efficient force transfer during archery shooting. Understanding the immediate effects of core stabilization exercises may support their use as an effective warm-up and performance-enhancing strategy in archery athletes.",[554,97,29],"Archery","2026-01-04",{"date":557,"type":41},"2026-01-14",{"date":559,"type":41},"2025-06-03",{"date":129,"type":21},{"name":562,"class":80},"Atlas University",{"id":564,"slug":565,"hasResults":12,"nctId":566,"briefTitle":567,"officialTitle":568,"acronym":569,"eligibilityCriteria":570,"healthyVolunteers":12,"sex":17,"minAge":571,"maxAge":4,"enrollmentInfo":572,"targetDuration":4,"studyType":22,"phases":574,"briefSummary":575,"conditions":576,"keywords":578,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":587,"lastUpdatePostDateStruct":588,"startDateStruct":590,"completionDateStruct":592,"leadSponsor":593,"locationsCount":48},"100618651","impact-of-a-multicomponent-exercise-program-on-cognitive-and-functional-outcomes-in-patients-with-mild-cognitive-impairment-100618651","NCT07334392","Impact of a Multicomponent Exercise Program on Cognitive and Functional Outcomes in Patients With Mild Cognitive Impairment","Effectiveness of an Innovative Therapeutic Exercise Program on Physical and Cognitive Function in Mild Cognitive Impairment Due to Alzheimer's Disease","MExeProMCI","Inclusion Criteria:\n\n* individuals \\> 50 years old\n* people with confirmed cognitive impairment, as evidenced by values within normal limits on the Montreal Cognitive Assessment test (MOCA ) \\>20\n* stable medication in the last month\n* independent walking\n\nExclusion Criteria:\n\n* people with dementia\n* people suffering from chronic mental illness (e.g. schizophrenia, bipolar disorder)\n* people suffering from a neurological disorder or injuries (e.g. multiple sclerosis, Parkinson's, traumatic brain injury)\n* people with clinical depression (as determined by the Neuropsychiatric Inventory (NPI) assessment and medical diagnosis)\n* people who have had recent surgery\n* people with insufficient knowledge of the Greek language","50 Years",{"count":573,"type":21},45,[24],"The goal of this randomised clinical trial is to investigate the effectiveness of an innovative therapeutic exercise program emphasizing in dual-task exercises in people with amnestic Mild Cognitive Impairment. The main questions it aims to answer are:\n\nDoes the innovative therapeutic exercise program improve gait and balance? Does the innovative therapeutic exercise program improve cognition?\n\nResearchers will compare the innovative therapeutic exercise program emphasizing in dual-task exercises to a therapeutic exercise program without emphasizing in dual-task exercises and to a control group (given instruction about the benefits of exercise).\n\nParticipants will:\n\n* Perform the exercise program twice a week for three months.\n* Will be assessed before and after the intervention.\n* Will record The Borg Scale of Perceived Exertion every second week to monitor and assess the progression of exercise intensity.",[577,150,29,205],"Mild Cognitive Impairment",[579,179,580,581,582,583,584,585,586],"kinetic and kinematic","global cognition","executive function","attention","mci","multicomponent program","exercise","dual tasking","2025-12-30",{"date":589,"type":41},"2026-01-12",{"date":591,"type":41},"2025-12-01",{"date":322,"type":21},{"name":594,"class":80},"University of Patras",{"id":596,"slug":597,"hasResults":12,"nctId":598,"briefTitle":599,"officialTitle":600,"acronym":601,"eligibilityCriteria":602,"healthyVolunteers":56,"sex":17,"minAge":118,"maxAge":142,"enrollmentInfo":603,"targetDuration":4,"studyType":92,"phases":4,"briefSummary":605,"conditions":606,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":610,"lastUpdatePostDateStruct":611,"startDateStruct":613,"completionDateStruct":615,"leadSponsor":617,"locationsCount":48},"100606782","figure-of-eight-backward-walk-test-in-elderly-100606782","NCT07180030","Figure-of-eight Backward Walk Test in Elderly","Determination of Reliability, Validity, and Minimal Detectable Change (MDC) of the Figure-of-eight Backward Walking Test in Elderly Adults","elderly","Inclusion Criteria:\n\n* Healthy elderly individuals over 65 years of age.\n* Elderly individuals who have fluent in Turkish and able to communicate.\n* Elderly individuals who have no cognitive impairment.\n\nExclusion Criteria:\n\n* Elderly individuals who have any neurological problems (Parkinson's, hemiplegia, etc.)\n* Elderly individuals who have any orthopedic problems (fractures, etc., in the last year)\n* Elderly individuals who have a body mass index (BMI) ≥ 40 kg\u002Fm2\n* Elderly individuals who havevision problems\n* Elderly individuals who have had any lower extremity surgery in the last year\n* Elderly individuals who use any mobility aids\n* Elderly individuals who refuse to participate in the study.",{"count":604,"type":21},87,"Mobility is a fundamental element of healthy aging. Balance is a necessary function during mobility for all movements throughout life in elderly individuals. Falls due to balance disorders in elderly individuals cause a decrease in the quality of life. Studies in the literature indicate that 13% of individuals aged 65-69 experience falls, and this rate rises to 46% in individuals over 85. Lower extremity muscle volume and strength gradually decrease with aging. This decreased muscle strength directly impacts individuals' activities of daily living.Normal walking speed for elderly individuals is related to balance and overall health performance. However, walking assessments generally focus on walking activities in a forward direction and in a straight line. However, in daily life, we may need to sit on a chair, walk backward to navigate a narrow space, or change direction suddenly due to obstacles or environmental cues. Walking backward requires more complex motor control, and these gait training programs are known to be effective in improving balance and walking skills.Clinically, balance assessments in the elderly persons are commonly measured by using the TUG, 10-meter walk test, functional reach test, 4-square step test, and Berg balance scale. The methods used to assess balance are still not fully standardized. The best test for assessing dynamic balance and fall risk is still up for debate, especially when it comes to elderly individuals who live freely in the community. Further research is needed to determine whether lateral walking tests can identify those at high risk of falling in elderly adults. The purpose of this study was to determine the reliability, validity, and minimal detectable change (MDC) of the Figure-of-8 backward walking test in healthy elderly adults.",[607,29,608,609],"Elderly (People Aged 65 or More)","Dynamic Balance","Backward Walking","2025-12-18",{"date":612,"type":41},"2025-12-19",{"date":614,"type":41},"2025-05-01",{"date":616,"type":21},"2026-01-30",{"name":618,"class":80},"Kahramanmaras Sutcu Imam University",{"id":620,"slug":621,"hasResults":12,"nctId":622,"briefTitle":623,"officialTitle":624,"acronym":4,"eligibilityCriteria":625,"healthyVolunteers":12,"sex":626,"minAge":378,"maxAge":58,"enrollmentInfo":627,"targetDuration":4,"studyType":22,"phases":629,"briefSummary":630,"conditions":631,"keywords":640,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":644,"lastUpdatePostDateStruct":645,"startDateStruct":647,"completionDateStruct":649,"leadSponsor":651,"locationsCount":48},"100584927","the-myofascial-system-and-minimizing-the-risk-os-injury-in-sport-100584927","NCT06895720","THE MYOFASCIAL SYSTEM AND MINIMIZING THE RISK OS INJURY IN SPORT","EFFECT OF SELF-MYOFASCİAL RELEASE ON MUSCLE MECHANİCAL PROPERTİES, PERFORMANCE, NEUROMUSCULAR FUNCTİON AND MİNİMİZATİON OF İNJURY RİSK İN YOUNG SOCCER PLAYERS","Inclusion Criteria:\n\n* Athletes at the youth and junior levels\n* Registered with the respective football association\n* Athletes with no history of injury in the past 3 months\n\nExclusion Criteria:\n\n* Athletes who failed pre-season medical examinations\n* Athletes with a history of previous surgery or lower limb fractures in the last 5 years\n* Athletes undergoing physiotherapy rehabilitation at the time of the study\n* Athletes participating in another injury prevention program or specific training","MALE",{"count":628,"type":21},65,[24],"The aim of the study is to evaluate the effect of myofascial self-release on muscle mechanical properties, performance, neuromuscular function, and injury risk reduction in young soccer players. The hypothesis is a reduction in the number of injuries in the experimental group, as well as improvements in muscle mechanical properties, performance, and neuromuscular function in young soccer players.The study will be a randomized clinical trial with a convenience sample of approximately 65 male athletes aged between 14 and 18 years, divided into control and experimental groups. Athletes with no history of injury in the three months prior to the study will be included, while those with a history of previous surgery or lower limb fractures in the past five years, or who are undergoing physiotherapy at the time of the study, will be excluded.Muscle mechanical properties (myotonometry), flexibility (sit-and-reach test), ankle dorsiflexion range of motion (Weight Bearing Lunge Test), motor control (Y Balance Test), and the reactive strength index (Myjump App) will be assessed before, immediately after, and at 8 and 16 weeks post-intervention. Myofascial self-release will be performed bilaterally on the quadriceps, hamstrings, and calves for 2 minutes per region, twice a week, using a structured massage roller. All procedures will be demonstrated beforehand during the study.\n\nFor the Myoton procedure, the athlete will simply lie in a supine and prone position on the examination table. The athlete will only be asked to remain still in the \"face-up\" or \"face-down\" position, feeling only the light contact of the device's probe, which is painless and will be demonstrated beforehand.\n\nIn the Y Balance Test, athletes will be asked to balance on one foot atop a grid placed on the floor, with their hands on their hips, and reach as far as possible with the non-supporting leg in three marked directions on the floor, without lifting the heel of the supporting leg.\n\nFor the Ankle Range of Motion - Weight Bearing Lunge Test, the athlete will place the tested foot on a measuring tape positioned on the floor and will be instructed to touch their knee to the wall in front of them without lifting the heel of the tested foot. Three attempts will be allowed, and the longest distance from the big toe to the wall will be recorded.\n\nIn the Sit-and-Reach Test, the athlete will sit on the floor with bare feet and both legs extended. They will be instructed to keep their hands side by side and try to reach the greatest possible distance on the ruler in front of them by bending forward without bending their legs, holding the position for one second to measure the distance. Three attempts will be allowed, and the greatest distance reached will be recorded.\n\nFor ground reaction strength, the athlete will be asked to jump off a 40 cm high box, and as soon as their feet touch the ground, they will be encouraged to jump upward as quickly and as high as possible.\n\nIn myofascial self-release, athletes in the experimental group will be asked to use the myofascial release roller for 2 minutes before training on each of the three muscle groups - anterior and posterior thigh and posterior leg. Athletes will be instructed to roll using as much pressure as possible on the roller. For the anterior thigh, they will roll across the entire front part of the thigh; for the posterior thigh, they will roll from just below the gluteal region to just above the knee; and for the posterior leg, they will roll from just below the knee to just above the heel.",[632,633,29,634,635,636,637,638,639],"Sports Injuries","Flexibility","Jumping Performance","Muscle Tonus","Ranger of Motion","Reactive Strength Index","Muscle Stiffness","Muscle Elasticity",[641,642,643],"Self-myofascial release","Injury prevention","Muscle mechanical properties","2025-11-25",{"date":646,"type":41},"2025-12-02",{"date":648,"type":21},"2026-01-01",{"date":650,"type":21},"2026-04-30",{"name":652,"class":80},"Aveiro University",{"id":654,"slug":655,"hasResults":12,"nctId":656,"briefTitle":657,"officialTitle":658,"acronym":4,"eligibilityCriteria":659,"healthyVolunteers":12,"sex":17,"minAge":89,"maxAge":660,"enrollmentInfo":661,"targetDuration":4,"studyType":22,"phases":663,"briefSummary":664,"conditions":665,"keywords":670,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":673,"lastUpdatePostDateStruct":674,"startDateStruct":676,"completionDateStruct":678,"leadSponsor":680,"locationsCount":48},"100610918","effects-of-fun-core-child-friendly-core-stabilization-exercises-on-balance-and-functional-mobility-in-children-with-spastic-cerebral-palsy-100610918","NCT07233824","Effects of Fun-Core (Child-Friendly Core Stabilization) Exercises on Balance and Functional Mobility in Children With Spastic Cerebral Palsy","Effects of Fun-Core (Child-Friendly Core Stabilization) Exercises on Balance and Functional Mobility in Children With Spastic Cerebral Palsy: A Single-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Children with hemiplegic cerebral palsy between the ages of 6 and 12\n* Children with Gross Motor Function Classification System (GMFCS) Levels 1, 2, and 3\n* Shoe sizes 30 and above\n\nExclusion Criteria:\n\n* Cognitive impairments that prevent understanding and performing simple commands and tasks\n* Botulinum toxin injections into the upper and\u002For lower extremities within the last 6 months\n* History of lower extremity or lumbar surgery within the last year\n* Presence of uncontrolled severe epileptic seizures\n* Presence of severe vision or hearing problems\n* Presence of fixed contractures in the lower extremities","12 Years",{"count":662,"type":21},54,[24],"A total of 54 children, aged between 6 and 12 years, diagnosed with hemiplegic cerebral palsy and not meeting the exclusion criteria, who registered at the outpatient clinics of the Department of Physical Medicine and Rehabilitation, Istanbul University, Istanbul Faculty of Medicine, between June 1, 2025 and March 1, 2026, were planned to be included in our thesis study, which was planned to be prospective, randomized and single-blind. Children and their parents will be informed verbally and in writing about the study's purpose, duration, and method of implementation, and their informed consent will be obtained. They will be asked to sign an \"Informed Consent Form.\" Patient assessment and follow-up forms will be completed at pre- and post-treatment follow-ups. Patients who meet the inclusion criteria will be numbered according to their order of admission and then randomly assigned to either the intervention or control groups by a computer program.\n\nIn addition to a brochure showing the number of sets and repetitions to be given to the patients as a standard home exercise program, the Fun-Core video exercise program, designed as a child-friendly core stabilization exercise program to be performed 3 times a week, will be given to the intervention group (G1), and the exercises will be delivered to the participants through a website with special accounts.\n\nThe control group (G2) will receive a standard home exercise program in brochure format, showing the number of sets and repetitions. The exercise program will be performed at home three times a week for 8 weeks.",[666,384,667,668,669,29],"Hemiplegic Cerebral Palsy","Core Stabilization","Exercise","Functional Mobility",[671,390,180,179,672],"core stabilization exercises","child friendly","2025-11-16",{"date":675,"type":41},"2025-11-18",{"date":677,"type":41},"2025-09-17",{"date":679,"type":21},"2026-05-31",{"name":681,"class":80},"Istanbul University",{"id":683,"slug":684,"hasResults":12,"nctId":685,"briefTitle":686,"officialTitle":687,"acronym":4,"eligibilityCriteria":688,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":689,"targetDuration":4,"studyType":22,"phases":691,"briefSummary":692,"conditions":693,"keywords":4,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":695,"lastUpdatePostDateStruct":696,"startDateStruct":698,"completionDateStruct":699,"leadSponsor":700,"locationsCount":4},"100587399","effects-of-whole-body-vibration-therapy-on-cognitive-function-balance-and-quality-of-life-in-older-adults-with-mild-cognitive-impairment-100587399","NCT06927882","Effects of Whole Body Vibration Therapy on Cognitive Function, Balance, and Quality of Life in Older Adults With Mild Cognitive Impairment","Effects of Whole Body Vibration Therapy on Cognitive Function, Balance, and Quality of Life in Older Adults With Mild Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled Trial","Inclusion Criteria:\n\n* Adults aged 60 years and older.\n* Diagnosed with mild cognitive impairment (Montreal Cognitive Assessment (MoCA) score of 18-25). One point is added if years of education are less than 12 years\\[2\\].\n* Able to stand independently or with minimal assistance.\n* No contraindications for WBV therapy or exercise.\n\nExclusion Criteria:\n\n* Diagnosis of dementia.\n* Severe musculoskeletal or neurological disorders.\n* Implanted electronic medical devices (e.g., pacemaker).\n* Inability to comprehend study instructions.",{"count":690,"type":21},180,[24],"This is a double-blind, randomized controlled trial comparing WBV therapy with a placebo intervention and standard care. A total of 150 participants will be recruited and investigated from Prince Mutib Hospital. Participants will be randomly allocated to one of three groups: WBV therapy, placebo (non-vibrating platform), or control (standard care). The study duration will be 12 weeks, with assessments conducted at baseline, post-intervention (12 weeks), and at a 6-month follow-up.\n\nProtocol Parameters Summary\n\n* Session Frequency: 3 times per week.\n* Session Duration: 25 minutes per session.\n* Vibration Frequency: 30 Hz.\n* Amplitude: 1-2 mm.\n* Program Duration: 12 weeks.",[694,29,440],"Cognitive Impairment","2025-11-14",{"date":697,"type":41},"2025-11-17",{"date":75,"type":21},{"date":587,"type":21},{"name":701,"class":80},"Jouf University"]