[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bariatric-patients-undergoing-bariatric-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bariatric-patients-undergoing-bariatric-surgery":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100627788","transabdominal-and-laparoscopic-ultrasound-in-a-bariatric-setting-100627788",false,"NCT07453186","Transabdominal and Laparoscopic Ultrasound in a Bariatric Setting","Transabdominal and Laparoscopic Ultrasound in a Bariatric Setting: Utility and Diagnostic Accuracy","Inclusion Criteria:\n\n* Age ≥18 years\n* Scheduled for bariatric surgery\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Previous cholecystectomy\n* Previous biliary surgery\n* Previous liver surgery\n* Inability to provide informed consent",true,"ALL","18 Years",{"count":20,"type":21},130,"ESTIMATED","INTERVENTIONAL",[24],"NA","Every year, many patients undergo weight-loss (bariatric) surgery. While this surgery leads to significant and intended weight loss, it also increases the risk of developing gallstones or other gallbladder problems.\n\nApproximately one in five patients later requires a second operation to remove the gallbladder. This type of surgery carries a higher risk of complications and reoperations compared with gallbladder surgery performed in the general population.\n\nPreventive treatment may help reduce this risk. One option is medical treatment with Ursochol, which has been shown to lower the risk of developing gallstones after bariatric surgery. However, this treatment is only effective in patients who have not already developed gallstones before surgery.\n\nThis means patients need a reliable preoperative ultrasound examination of the gallbladder. Unfortunately, performing ultrasound can be technically challenging in patients with obesity, making it harder to detect small stones or other abnormalities.\n\nThe goal is therefore to improve the examination of the gallbladder in patients undergoing bariatric surgery in order to better identify who may benefit from preventive treatment.\n\nThe study\n\nThe investigators are comparing two types of ultrasound examination of the gallbladder:\n\n* Standard ultrasound performed on the outside of the abdomen using a handheld probe.\n* Laparoscopic ultrasound performed during bariatric surgery using a small ultrasound probe placed inside the abdomen, typically placed on the liver near the gallbladder.\n\nIt is of interest to find out whether the ultrasound performed during surgery finds more:\n\n* Gallstones\n* Sludge\n* Small stones (microlithiasis)\n* Thickening of the gallbladder wall\n\nBy improving detection, the investigators aim to better guide preventive treatment and reduce the need for future gallbladder surgery.",[27,28,29],"Gallstone Disease","Ultrasonic Diagnosis","Bariatric Patients Undergoing Bariatric Surgery",[31,32,33,34,35,36],"Bariatric surgery","Gallstone disease","Metabolic surgery","Biliary disease","Ultrasound","Laparoscopic ultrasound","RECRUITING","2026-05-29",{"date":40,"type":41},"2026-06-02","ACTUAL",{"date":43,"type":41},"2026-04-01",{"date":45,"type":21},"2029-03-01",{"name":47,"class":48},"Esbjerg Hospital - University Hospital of Southern Denmark","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":57,"targetDuration":59,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":66,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":49},"100562121","regional-adipose-tissue-characteristics-in-type-ii-diabetes-100562121","NCT06599047","Regional Adipose Tissue Characteristics in Type II Diabetes","Inclusion Criteria:\n\n* Men, premenopausal and postmenopausal females between 18-65 years\n* Anticipating having bariatric surgery (participants with obesity) or general surgery in the abdominal area (normal weight participants) with a duration of less than 1.5 hours.\n* BMI 30 kg \u002F m2 (participants with obesity)\n* Weight Stable for a minimum of two months prior to the first pre-op visit\n\nExclusion Criteria:\n\n* Smoking\n* Renal impairment defined by creatinine clearance; 60 ml\u002Fminute\n* Uncontrolled hypothyroidism\n* No comorbidity other than diabetes type II Exceptions: controlled hypertension, hypothyroidism controlled, controlled dyslipidemia\n* Use prescribed medication that affect our outcomes E.g. Exceptions include metformin, DPP-4 inhibitors, inhibitors of the α-glucosidase, hypotensive with a stable dose for 3 months lipid lowering with a stable dose for 3 months.","65 Years",{"count":58,"type":21},140,"1 Year","OBSERVATIONAL","Fat tissue in different parts of the body has different characteristics. Several studies have associated abdominal fat to an increased risk for multiple metabolic diseases, such as type 2 diabetes and cardiovascular disease, compared with fat located under the skin at the hips and thighs. However, the investigators do not know how the abdominal fat causes or contributes to the development of these diseases or how the development of these disease may in turn cause or contribute to changes in the fat tissue. The general objective of this study is to understand these mechanisms.\n\nTo investigate these questions, the study will recruit 140 participants, both men and women aged 18-65 years. The participants will be divided into three groups: 40 people with obesity, 40 with diabetes, and 60 lean individuals. Participants will be recruited from patients at the CIUSSS du Nord-de-l'Île-de Montréal - Hôpital du Sacré-Coeur de Montréal who are awaiting bariatric or general abdominal surgery, as well as from the general population in the Montreal area.",[63,29,64,65],"Obesity and Type 2 Diabetes","Adipose Tissue Dysfunction Type 2 Diabetes Mellitus Bariatric Surgery","Adipose Tissue Inflammation",[67,68,69,70,65],"obesity","Type 2 diabetes","Bariatric Surgery","Adipose Tissue Characterization","2024-10-20",{"date":73,"type":41},"2024-10-22",{"date":75,"type":41},"2016-05-01",{"date":77,"type":21},"2025-12",{"name":79,"class":48},"Concordia University, Montreal"]