[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bariatric-surgery-status-complicating-pregnancy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bariatric-surgery-status-complicating-pregnancy":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100445738","glucose-homeostasis-metabolomics-and-pregnancy-outcomes-after-bariatric-surgery-100445738",false,"NCT05084339","Glucose Homeostasis, Metabolomics and Pregnancy Outcomes After Bariatric Surgery","GLORIA","Inclusion Criteria:\n\n* Age 18-45 years and with a singleton pregnancy with ultrasound-confirmed gestational age up to 11 weeks and 6 days\n* for the group with bariatric surgery: history of gastric bypass (RYBG) or sleeve gastrectomy (SG)\n* Participants need to speak and understand Flemish, French or English and have e-mail access.\n\nExclusion Criteria:\n\n* multiple pregnancy\n* pregnancy ≥12 weeks\n* other types of bariatric surgery than RYBG or SG\n* known pregestational diabetes\n* a physical or psychological disease likely to interfere with the conduct of the study\n* medications known to interfere with glucose metabolism.",true,"FEMALE","18 Years","45 Years",{"count":21,"type":22},190,"ESTIMATED","OBSERVATIONAL","The aim of the GLORIA study is to determine whether an altered glucose metabolism (with more hypoglycaemia and glycaemic variability) and altered metabolomics during pregnancy after bariatric surgery contribute to the increased risk for adverse pregnancy outcomes such as small-for-gestational age infants. In addition, the investigators also aim to evaluate whether continuous glucose monitoring (CGM) can be used to diagnose gestational diabetes (GDM).",[26],"Bariatric Surgery Status Complicating Pregnancy","RECRUITING","2026-04-28",{"date":30,"type":31},"2026-05-05","ACTUAL",{"date":33,"type":31},"2023-01-25",{"date":35,"type":22},"2026-12",{"name":37,"class":38},"Universitaire Ziekenhuizen KU Leuven","OTHER",8,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":47,"enrollmentInfo":48,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":50,"conditions":51,"keywords":56,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100497121","effect-of-obesity-diabetes-and-bariatric-surgery-on-pregnancy-outcomes-100497121","NCT05753124","Effect of Obesity, Diabetes and Bariatric Surgery on Pregnancy Outcomes","Investigation and Study of Pregnancy in Overweight or Diabetic Women and the Effect of Bariatric Surgery on Pregnancy Outcomes","Inclusion Criteria:\n\n* Pregnant women with normal size (BMI \\\u003C30)\n* Pregnant women with obesity (BMI ≥30)\n* Pregnant women with glucose disorders\n* Pregnant women with previous bariatric surgery\n\nExclusion Criteria:\n\n* Pregnant women less than 18 years of age\n* Pregnant women with twins\u002Ftriplets","50 Years",{"count":49,"type":22},700,"The obesity epidemic is growing worldwide and in the UK this is perpetuated with a third of women classified as overweight\u002Fobese in 2020. Many of these woman are of childbearing age and go on to have high risk pregnancies which are often complicated by gestational or pre-existing (type 2 diabetes mellitus (GDM, T2DM). Bariatric surgery is the most successful treatment of sustainable weight loss and is associated with a reduction in rates of GDM, pre-eclampsia, delivery of large babies but increased risk of delivery of small babies and preterm delivery.\n\nThe aims of the study are to investigate the maternal and fetal\u002Fneonatal, biophysical and biochemical, intra-uterine environment and postnatal profile of pregnancies:\n\n1. affected by maternal obesity and\u002For GDM\u002FT2DM compared to pregnancies with normal maternal body mass index (BMI).\n2. with previous maternal bariatric surgery compared to pregnancies without previous bariatric surgery but matched for maternal pre-surgery and early pregnancy BMI.",[52,53,54,55,26],"Obesity","Pregnancy in Diabetic","Pregnancy Complications","Pregnancy Related",[57,58,59,60,61,62],"Pregnancy","Gastric sleeve","Gastric bypass","Bariatric surgery","Birth weight","Glucose intolerance","2023-03-01",{"date":65,"type":31},"2023-03-03",{"date":67,"type":31},"2015-05",{"date":69,"type":22},"2027-10",{"name":71,"class":38},"Chelsea and Westminster NHS Foundation Trust",1]