[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"behavior-health\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:behavior-health":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,13,0,[8,41,71,103,128,145,185,219,244,281,310,339,373],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100519999","healthy-weight-intervention-families-during-all-treatment-nourish-all-100519999",false,"NCT06050850","Healthy Weight Intervention Families During ALL Treatment: NOURISH-ALL","A Healthy Weight Intervention for Family Stress During the Early Phases of ALL Treatment: NOURISH-ALL","NOURISH-ALL","Inclusion Criteria:\n\n* Children ages 2-12 years old and their primary caregiver ages 18-90\n* Child diagnosed with acute lymphoblastic leukemia (ALL)\n* Child completed induction phase of therapy and not yet in maintenance phase of therapy\n* Primary caregiver and child English language proficient\n* Primary caregiver able to provide permission for child to participate in research\n* Primary caregiver identifies as being involved with child's oncology care\n* Primary caregiver lives with child at least 50% of the time\n* Primary oncology provider confirms child is eligible to participate\n\nExclusion Criteria:\n\n* Primary oncology provider identifies safety concerns regarding the child's participation in the study.","ALL","2 Years","12 Years",{"count":21,"type":22},46,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to conduct a single arm pilot of the NOURISH-ALL (Nourishing Our Understanding of Role modeling to Improve Support and Health in Acute Lymphoblastic Leukemia) intervention focused on three components of participant engagement. This is a single arm intervention study that involves participation in a 6-session family intervention and three time points of multimethod data collection. The primary outcome is participant engagement, measured as recruitment, retention, and intended dose received.\n\nThis study will be conducted over 5 years in three phases:\n\n* Aim 1a: Adapting the NOURISH-ALL Intervention for Families of Youth with ALL (Year 1)\n* Aim 1b: Iteratively Refining the NOURISH-ALL Intervention (Year 2)\n* Aim 2: Pilot Single-Arm Trial of NOURISH-ALL Focused on Participant Engagement (Years 3-5)",[26,27],"ALL, Childhood","Behavior, Health","RECRUITING","2026-06-30",{"date":31,"type":32},"2026-07-02","ACTUAL",{"date":34,"type":32},"2023-10-17",{"date":36,"type":22},"2028-09-01",{"name":38,"class":39},"University of Kansas Medical Center","OTHER",2,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":17,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":60,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":40},"100514906","personalized-health-self-management-training-for-colorectal-cancer-survivors-100514906","NCT05984589","Personalized Health Self-Management Training for Colorectal Cancer Survivors","A Prospective, Randomized, Controlled, Double-Arm Study of RISE (Re-Invent, Integrate, Strengthen, Expand) Personalized Self-Management Training (PSMT) Compared to Standardized Self-Management Training (SSMT) in Gastrointestinal Cancer (GI) Patients","Inclusion Criteria:\n\n* Age ≥18 years at the time of consent.\n* History of Stage I-IV colorectal cancer (CRC) or other gastrointestinal cancer within the past 10 years prior to enrollment.\n* Ability to speak, write, and read English sufficiently to allow for program participation.\n* Identified by self-report as having willingness and interest to work on at least one lifestyle-related risk factor. Lifestyle-related risk factors include diet, physical activity, body composition, alcohol use.\n* Scoring ≤3.5 on the World Cancer Research Fund\u002FAmerican Institute for Cancer Research (WCRF\u002FAICR) Health Behavior Adherence Scale or in the low-to-moderate range in any subcategory consistent with moderate to low adherence to healthy behavior recommendations (HBRs).\n* Ambulatory and independent in activities of daily living (ADL).\n* Written informed consent obtained from subject and ability for subject to comply with the requirements of the study.\n\nExclusion Criteria:\n\n* Cognitive or mental impairments that in the opinion of the Principal Investigator or study physician would hinder the program participation.","18 Years",{"count":50,"type":22},120,"INTERVENTIONAL",[53],"NA","This is a Phase 2 prospective, randomized, controlled, double-arm study to assess personalized self-management training (PSMT) intervention efficacy and patient experiences compared to standardized self-management training (SSMT). A total of 120 gastrointestinal (GI) cancer patients will be enrolled and randomized 1:1 to complete a 6-week self-management training program (either PSMT or SSMT) to be carried out by licensed occupational therapists with doctoral training.\n\nThis study aims to examine whether PSMT is more effective in increasing adherence to healthy behavior recommendations compared to SSMT in GI cancer patients.",[56,57,27,58,59],"Colorectal Cancer","Healthy Lifestyle","Health Behavior","Gastrointestinal Cancers",[61],"self-management training","2026-06-08",{"date":64,"type":32},"2026-06-10",{"date":66,"type":32},"2024-03-01",{"date":68,"type":22},"2028-11-30",{"name":70,"class":39},"University of Southern California",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":78,"minAge":48,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":51,"phases":81,"briefSummary":82,"conditions":83,"keywords":87,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":102},"100486871","healthy-for-two-home-visiting-h42-hv-health-coaching-for-pregnant-women-100486871","NCT05619705","Healthy for Two-Home Visiting (H42-HV): Health Coaching for Pregnant Women","Effectiveness of Health Coaching to Reduce Cardiometabolic Risk in Early Home Visiting Services","Inclusion Criteria:\n\n* Pregnant, ≤33 weeks gestation\n* Singleton pregnancy\n* Pre pregnancy BMI≥25.0 Kg\u002Fm\\^2 (calculated based on self-reported pre pregnancy height and weight)\n* Able to provide informed consent\n* English or Spanish speaking\n* Completion of screening and baseline data collection\n* Willing to participate in the intervention and data collection procedure (e.g., home weights)\n\nExclusion Criteria:\n\n* Type 1 diabetes or taking insulin prior to delivery\n* Pregnant with multiple fetuses\n* Unable to walk 1 block without pain or shortness of breath\n* Not cleared by the study's clinicians or home visiting program staff\n* Planning to relocate from area during next 1 year\n* Active substance abuse disorder (except marijuana)\n* Psychiatric or substance use related hospitalization in past 1 year\n* Active eating disorder","FEMALE",{"count":80,"type":22},360,[53],"The purpose of this study is to compare the effectiveness of H42-HV integrated into home visiting compared with usual home visiting services in reducing postpartum weight retention (difference between pre-pregnancy weight and weight at 6 months postpartum) among pregnant and postpartum participants. The overall goal is to improve long-term cardiometabolic health.",[84,85,86,27],"Postpartum Weight Retention","Pregnancy Weight Gain","Overweight and Obesity",[88,89,90,91,92,93],"Behavioral Intervention","Early Childhood Home Visiting","Overweight","Obesity","Postpartum","Pregnancy","2026-06-04",{"date":62,"type":32},{"date":97,"type":32},"2023-04-25",{"date":99,"type":22},"2026-12-15",{"name":101,"class":39},"Johns Hopkins University",1,{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":107,"acronym":108,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":17,"minAge":48,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":51,"phases":112,"briefSummary":113,"conditions":114,"keywords":115,"overallStatus":119,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":124,"leadSponsor":126,"locationsCount":102},"100643396","colorectal-cancer-screening-preventive-reminder-ordering-assistance-via-texting-for-improved-visit-encounters-100643396","NCT07636174","Colorectal Cancer Screening Preventive Reminder Ordering AssistanCe Via Texting for Improved Visit Encounters","CRC PROACTIVE","Inclusion Criteria:\n\nAll patients must meet the following criteria to be eligible:\n\n1. Age 18 years or older\n2. A scheduled new or return (non-urgent\u002Fsick) primary care visit at one of the study practices\n3. Overdue for colorectal cancer screening by health maintenance\n4. Ordered for FIT or Colonoscopy at the eligible visit\n\nExclusion Criteria:\n\nAs this trial is integrated with routine clinical operations, there will be no exclusion criteria other than already having an eligible visit at some point during the trial duration with an order for FIT or Colonoscopy.",{"count":111,"type":22},3888,[53],"Colorectal cancer (CRC) is the second leading cause of cancer death in the United States. A substantial portion of the United States population remains overdue for screening, despite availability and insurance coverage of preventive health services. Barriers for completion and remaining up to date with screening include patients not remaining actively engaged with their care team, time constraints during office visits, and operational strain. This project aims to implement and evaluate a primary care visit-based outreach program that improves patient follow through on completion of overdue CRC screening.\n\nThis will be a 6 month, stepped-wedge, pragmatic trial conducted at Penn Medicine.",[27],[116,117,118],"EHR Nudge","Behavioral Economics","Preventive Health","NOT_YET_RECRUITING","2026-06-03",{"date":122,"type":32},"2026-06-09",{"date":62,"type":22},{"date":125,"type":22},"2027-05-23",{"name":127,"class":39},"University of Pennsylvania",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":132,"acronym":133,"eligibilityCriteria":134,"healthyVolunteers":11,"sex":17,"minAge":48,"maxAge":4,"enrollmentInfo":135,"targetDuration":4,"studyType":51,"phases":137,"briefSummary":138,"conditions":139,"keywords":140,"overallStatus":119,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":141,"startDateStruct":142,"completionDateStruct":143,"leadSponsor":144,"locationsCount":102},"100643330","preventive-reminder-ordering-assistance-via-texting-for-improved-visit-encounters-100643330","NCT07636187","Preventive Reminder Ordering AssistanCe Via Texting for Improved Visit Encounters","PROACTIVE","Inclusion Criteria:\n\nAll patients must meet the following criteria to be eligible:\n\n1. 18 years or older\n2. A scheduled new or return (non-urgent\u002Fsick) primary care visit at one of the study practices\n3. Overdue for at least one of the included care gaps according to Health Maintenance: Mammogram, DEXA, Hemoglobin A1C, Basic Metabolic Panel, Urine Microalbumin, Lipids, Hepatitis C\n4. Last eligible office visit was greater than or equal to 3 months ago\n\nExclusion Criteria:\n\nAs this trial is integrated with routine clinical operations, there will be no exclusion criteria. However, for each care gap independently, we will exclude all patient visits throughout the remaining trial duration after the patient's first eligible office visit within the trial duration. In other words, each patient will contribute data from at most one eligible office visit.",{"count":136,"type":22},16416,[53],"A substantial portion of the United States population remains overdue for key screenings, despite availability and insurance coverage of preventive health services. Barriers for completion and remaining up to date with screening include patients not remaining actively engaged with their care team, time constraints during office visits, and operational strain. This project aims to implement and evaluate a primary care visit-based program that harmonizes multiple preventive health and chronic disease management care gaps, reduces staff burden, and improves ordering and subsequent patient follow through on completion of overdue care gaps.\n\nIn this study, we will evaluate nudges to clinicians and patients to help increase screening completion for multiple care gaps identified as high priority by primary care, including imaging (Mammogram, DEXA) and labs (Diabetes Management (Hemoglobin A1C, Basic Metabolic Panel, and Urine Microalbumin), Hepatitis C, and Lipids). This will be a 6 month, stepped-wedge, pragmatic trial conducted at Penn Medicine.",[27],[116,117,118],{"date":122,"type":32},{"date":62,"type":22},{"date":125,"type":22},{"name":127,"class":39},{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":151,"eligibilityCriteria":152,"healthyVolunteers":11,"sex":78,"minAge":48,"maxAge":4,"enrollmentInfo":153,"targetDuration":4,"studyType":51,"phases":155,"briefSummary":156,"conditions":157,"keywords":161,"overallStatus":119,"whyStopped":4,"lastUpdateSubmitDate":176,"lastUpdatePostDateStruct":177,"startDateStruct":179,"completionDateStruct":181,"leadSponsor":183,"locationsCount":4},"100635234","womenfocused-education-in-cardiac-rehabilitation-wecare-pilot-rct-100635234","NCT07550036","WomenFocused Education in CArdiac REhabilitation (WECARE) Pilot RCT","Women Education in CArdiac REhabilitation (WE CARE): a Pilot Randomized Controlled Trial for Effectiveness, Implementation, Utilization, and Acceptability of Cardiac College for Women Across Canada","WE-CARE","Inclusion Criteria:\n\n* Identify as a woman\n* Aged 18 years or older\n* Enrolled in a participating cardiac rehabilitation program\n* Diagnosis consistent with cardiac rehabilitation eligibility (e.g., coronary artery disease, myocardial infarction, revascularization procedures, spontaneous coronary artery dissection, myocardial infarction with non-obstructive coronary arteries, Takotsubo cardiomyopathy, or heart failure)\n* Able to provide informed consent\n* Able to participate in educational sessions in English or French (site-dependent)\n\nExclusion Criteria:\n\n* Medical, cognitive, or psychiatric conditions that would prevent participation in educational sessions or completion of study questionnaires\n* Inability to access or use online educational sessions or digital materials required for the intervention",{"count":154,"type":22},50,[53],"The goal of this pilot clinical trial is to learn if a women-focused education program can improve knowledge, health, and well-being in women with heart disease who are attending cardiac rehabilitation. It will also help researchers understand if this program can be delivered successfully in different rehabilitation programs.\n\nThe main questions it aims to answer are:\n\n* Is it feasible to deliver this women-focused education program within routine cardiac rehabilitation programs?\n* Do women who receive this program show improvements in heart health knowledge, quality of life, and healthy behaviours?\n\nResearchers will compare women who receive the Cardiac College for Women program plus usual cardiac rehabilitation to those who receive usual cardiac rehabilitation alone to see if the program leads to better outcomes.\n\nParticipants will:\n\n* Be randomly assigned to receive either the women-focused education program or usual care\n* Attend cardiac rehabilitation as part of their regular care\n* Complete questionnaires at the start and end of the program\n* (If in the intervention group) attend online education sessions and use supporting materials\n* (Optional) take part in a group discussion about their experience after completing the program",[158,159,160,27],"Cardiovascular Diseases","Heart Diseases","Health Knowledge, Attitudes, Practice",[162,163,164,165,166,167,168,169,170,171,172,173,174,175],"Cardiac Rehabilitation","Women's Health","Patient Education","Cardiovascular Disease Prevention","Secondary Prevention","Health Education","Women-Focused Care","Gender-Specific Care","Digital Health \u002F Virtual Care","Self-Management","Health Behaviour Change","Quality of Life","Feasibility Study","Pilot Randomized Controlled Trial","2026-04-17",{"date":178,"type":32},"2026-04-24",{"date":180,"type":22},"2026-09-01",{"date":182,"type":22},"2027-09-01",{"name":184,"class":39},"University Health Network, Toronto",{"id":186,"slug":187,"hasResults":11,"nctId":188,"briefTitle":189,"officialTitle":190,"acronym":191,"eligibilityCriteria":192,"healthyVolunteers":11,"sex":17,"minAge":193,"maxAge":19,"enrollmentInfo":194,"targetDuration":4,"studyType":51,"phases":196,"briefSummary":197,"conditions":198,"keywords":205,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":211,"startDateStruct":213,"completionDateStruct":215,"leadSponsor":217,"locationsCount":102},"100532095","early-life-intervention-in-pediatrics-supported-by-e-health-100532095","NCT06208345","Early Life Intervention in Pediatrics Supported by E-health","Early Life Intervention in Pediatrics Supported by E-health (ELIPSE I): Coaching Parents to Lower Obesity in Children. A Single-blind Randomized Controlled Parallel-group Clinical Trial.","ELIPSE-I","Inclusion Criteria:\n\n* German speaking parents\n* Any ethnic background\u002Frace\n* Children should live\u002Fgrow-up in the same household as the parental participant\n* Children with an age- and sex-matched BMI \\>97 centile according to Swiss national growth charts\n* Children who attend the outpatient weight management clinic at the Division of Pediatric Endocrinology at the University Children's Hospital Bern\n* Signed informed consent form from parent(s)\n\nExclusion Criteria:\n\n* Syndromic obesity\n* Known congenital disease affecting musculo-skeletal, cardiac or pulmonary function\n* Participation in another clinical trial targeting similar objectives","6 Years",{"count":195,"type":22},148,[53],"Childhood obesity in early life contributes to the development of specific NCDs, i.e. adult obesity. Unhealthy diet and low level of physical activity are lifestyle risk behaviors associated with chronic, systemic inflammation, which promotes the pathogenesis of NCDs. Early preventive measures to improve lifestyle behavior are of utmost importance. The aim of ELIPSE-I is to assess whether an eHealth application intervention for parents is feasible and efficacious in lowering total energy intake\u002Ftotal energy expenditure (TEI\u002FTEE) ratio in their children with BMI \\>97 centile (ELIPSE-I).",[199,200,201,202,203,204,27],"Adiposity","Childhood Obesity","Adolescent Obesity","Non-communicable Disease","Life Style","Behavior, Eating",[199,206,207,208,209],"Children","Adolescents","Prevention","eHealth","2026-02-12",{"date":212,"type":32},"2026-02-18",{"date":214,"type":32},"2024-02-16",{"date":216,"type":22},"2028-12-31",{"name":218,"class":39},"Insel Gruppe AG, University Hospital Bern",{"id":220,"slug":221,"hasResults":11,"nctId":222,"briefTitle":223,"officialTitle":224,"acronym":225,"eligibilityCriteria":226,"healthyVolunteers":11,"sex":17,"minAge":48,"maxAge":4,"enrollmentInfo":227,"targetDuration":4,"studyType":51,"phases":229,"briefSummary":230,"conditions":231,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":235,"lastUpdatePostDateStruct":236,"startDateStruct":238,"completionDateStruct":240,"leadSponsor":242,"locationsCount":102},"100560771","improving-congenital-heart-disease-care-100560771","NCT06581484","Improving Congenital Heart Disease Care","Improving Care for Adults With Congenital Heart Disease","EmpowerMyCH","Inclusion Criteria:\n\n* have congenital heart disease\n* 18 years or older\n* can sign the informed consent\n\nExclusion Criteria:\n\n* developmentally delayed\n* unable to consent",{"count":228,"type":22},1000,[53],"The theory-informed digital health intervention, called as \"Empower My Congenital Health (EmpowerMyCH)\" aims to activate and engage ACHD patients in building confidence toward navigating the adult healthcare system. This tool is built after incorporating the theories of behavior change, gathering inputs from target patients in all stages of its design and implementation. The key features of the tool include a digital medical passport, updated congenital information, community support, and patient stories and advice. The investigators aim to test the acceptability, feasibility, efficacy, and effectiveness of the intervention.",[232,27,173,233,234],"Congenital Heart Disease","Empowerment, Patient","Activation, Patient","2026-01-21",{"date":237,"type":32},"2026-01-23",{"date":239,"type":32},"2024-09-05",{"date":241,"type":22},"2027-08-31",{"name":243,"class":39},"University of California, San Francisco",{"id":245,"slug":246,"hasResults":11,"nctId":247,"briefTitle":248,"officialTitle":249,"acronym":250,"eligibilityCriteria":251,"healthyVolunteers":11,"sex":17,"minAge":48,"maxAge":252,"enrollmentInfo":253,"targetDuration":4,"studyType":51,"phases":255,"briefSummary":256,"conditions":257,"keywords":268,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":272,"lastUpdatePostDateStruct":273,"startDateStruct":275,"completionDateStruct":277,"leadSponsor":279,"locationsCount":102},"100531998","the-fit-with-us-study-100531998","NCT06207084","The Fit With Us Study","Precision-based Teleexercise Trial to Increase Adherence in People With Disabilities","FITWITHUS","Eligible participants must meet the following criteria to be included: (1) live with a permanent physical disability that limits their mobility; (2) be 18 to 89 years of age; (3) have broadband internet access; (4) be able to speak and read English; and (5) be able to attend coaching and training sessions during the weekdays.\n\nParticipants are excluded from participation if they (1) possess significant visual acuity that prevents seeing a computer screen to follow a home exercise program; (2) have been regularly engaging in exercise for the previous 3 months; (3) are unable to use their arms and their legs at all to exercise; (4) are unsafe to exercise; (5) self-report that they are currently pregnant","89 Years",{"count":254,"type":22},257,[53],"The purpose of this 32-week study is to use an innovative experimental design known as SMART (Sequential Multiple Assignment Randomized Trial), which will allow us to determine the best way to sequence the delivery of teleexercise (referred to as an adaptive intervention), combined with predictive analytics on participant adherence in a stepped program of physical activity interventions. All 257 participants will have access to a library of recorded video exercise content, and a weekly wellness article. Some participants will receive health coaching calls (1st randomization). Analytic data will be used to determine which participants are responding or not responding to the intervention. Participants not responding after 4 weeks will receive either live one-on-one or group exercise training (2nd randomization). After 8 weeks, the participant will receive only pre-recorded exercise content and articles for a 24-week maintenance phase (weeks 9-32). The study outcomes are: The effectiveness of the adaptive interventions; Exploring mediating and moderating variables; Sensitivity analysis of the predictive analytics.",[258,259,260,261,262,27,209,263,264,265,266,267],"Mobility Limitations","Disability Physical","Telehealth","Health Coaching","Physical Activity","Health Literacy","Self Efficacy","Fatigue","Usability","Predictive Model",[269,270,271],"telehealth","health coaching","disability","2026-01-07",{"date":274,"type":32},"2026-01-09",{"date":276,"type":32},"2024-09-01",{"date":278,"type":22},"2029-02-01",{"name":280,"class":39},"University of Alabama at Birmingham",{"id":282,"slug":283,"hasResults":11,"nctId":284,"briefTitle":285,"officialTitle":286,"acronym":4,"eligibilityCriteria":287,"healthyVolunteers":288,"sex":17,"minAge":289,"maxAge":4,"enrollmentInfo":290,"targetDuration":4,"studyType":51,"phases":292,"briefSummary":293,"conditions":294,"keywords":295,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":301,"lastUpdatePostDateStruct":302,"startDateStruct":304,"completionDateStruct":306,"leadSponsor":308,"locationsCount":40},"100534736","train-your-brain-20---improving-memory-and-decision-making-among-youth-100534736","NCT06242704","Train Your Brain 2.0 - Improving Memory and Decision Making Among Youth","Train Your Brain 2.0: Improving Memory and Decision Making to Improve Outcomes Among Youth - A Randomized Controlled Trial","Adolescent Inclusion Criteria:\n\n1. Between the ages of 11 and 15 and have a parent\u002Fguardian willing to provide consent for their participation\n2. Proficient in English\n3. Willing to commit to participate in computer-based trainings over the course of 5-8 weeks (duration dependent on site)\n4. Access to internet services, cell phone, and\u002For email\n5. Willing to receive\u002Fsend study-related text messages\n\nAdolescent Exclusion Criteria:\n\n1. Self-disclosure or identification with psychological disturbance, suicidality, or evidence of active suicide ideation\n2. Self-disclosure of current substance use disorder\n\nParent Inclusion Criteria:\n\n1. Provide consent for child's participation in study\n2. Proficient in English\n3. Access to internet services, cell phone, and\u002For email\n4. Willing to receive\u002Fsend study-related text messages\n\nParent Exclusion Criteria:\n\n1. Self-disclosure or identification with psychosis, suicidality, or evidence of active suicide ideation\n2. Self-disclosure of current substance use disorder",true,"11 Years",{"count":291,"type":22},72,[53],"The goal of this clinical trial is to deliver a computer-based working memory training program to improve delay discounting (DD) and prevent substance misuse among at-risk adolescents in a traditionally underserved area. Results from the study will inform future substance use prevention efforts targeted at youth exposed to adverse childhood experiences. Findings will also refine future models of intervention delivery in traditionally underserved communities.\n\nThe main aims of the project are are:\n\n1\\) To examine to examine changes in hypothesized mechanisms of substance use initiation and escalation, and 2) to assess whether changes in DD are a mechanism for reducing substance misuse during early adolescence. The investigators will evaluate whether changes in DD following active treatment predict substance use outcomes over the three-month follow-up period.",[27],[296,297,298,299,300],"delay discounting","computer-based intervention","executive functioning","substance use","working memory","2025-05-20",{"date":303,"type":32},"2025-05-25",{"date":305,"type":32},"2024-06-25",{"date":307,"type":22},"2026-08-01",{"name":309,"class":39},"Wayne State University",{"id":311,"slug":312,"hasResults":11,"nctId":313,"briefTitle":314,"officialTitle":315,"acronym":4,"eligibilityCriteria":316,"healthyVolunteers":288,"sex":78,"minAge":317,"maxAge":4,"enrollmentInfo":318,"targetDuration":4,"studyType":51,"phases":320,"briefSummary":321,"conditions":322,"keywords":323,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":330,"lastUpdatePostDateStruct":331,"startDateStruct":333,"completionDateStruct":335,"leadSponsor":337,"locationsCount":102},"100527296","parent-child-memory-study-improving-future-thinking-among-mothers-100527296","NCT06145919","Parent-Child Memory Study: Improving Future Thinking Among Mothers","Parent-Child Memory Study: Improving Future Thinking Among Mothers From a Traditionally Underserved Community to Reduce Harsh Parenting and Improve Child Outcomes - A Randomized Controlled Trial","Parent Inclusion Criteria:\n\n1. A mother and or grandmother from the Flint area with a child\u002Fgrandchild between the ages of 5-10 who can provide legal consent for that child\n2. Self-report that they have consistent contact with the child\u002Fgrandchild\n3. Willing to participate in the study\n4. Able to participate in written assessments and an intervention conducted in English\n5. Have a working cell phone that can receive and send text messages and be willing to receive\u002Fsend text messages as part of the study\n6. Have a phone or device that's able to use video conferencing software if interested in virtual participation\n\nParent Exclusion Criteria:\n\n1. Self-disclosed active suicidality\u002Fhomicidality\n2. Self-disclosed current bipolar disorder, schizophrenia, or psychosis\n3. Self-reported current and ongoing involvement with child protective services\n\nChild Inclusion Criteria:\n\n1. Children must be between the ages of 5-10 and have a mother\u002Fgrandmother willing to provide consent for their participation\n2. Willing to participate in parent-child observation sessions\n3. Elementary proficiency in English\n4. Willing to participate in study surveys\n\nChild Exclusion criteria:\n\n1. Self-disclosed active suicidality\u002Fhomicidality\n2. Self-disclosed current bipolar disorder, schizophrenia, or psychosis","5 Years",{"count":319,"type":22},144,[53],"Parents of children from impoverished communities are disproportionately more likely to engage in harsh physical discipline, which can lead to serious clinical outcomes, including suicidal ideation and attempts. One mechanism linking low resource environments and maladaptive parenting strategies is maternal delay discounting, or the tendency to value smaller, immediate rewards (such as stopping children's misbehavior via physical means) relative to larger, but delayed rewards (like improving the parent-child relationship). This study will examine the efficacy of implementing a low-cost, brief intervention targeting the reduction of maternal delay discounting to inform broader public health efforts aimed at improving adolescent mental health outcomes in traditionally underserved communities.",[27],[324,325,296,326,327,328,329],"episodic future thinking","episodic recent thinking","parent-child relations","low resource","Flint, Michigan","special play time","2025-05-12",{"date":332,"type":32},"2025-05-14",{"date":334,"type":32},"2024-02-06",{"date":336,"type":22},"2025-08-31",{"name":338,"class":39},"Henry Ford Health System",{"id":340,"slug":341,"hasResults":11,"nctId":342,"briefTitle":343,"officialTitle":344,"acronym":4,"eligibilityCriteria":345,"healthyVolunteers":288,"sex":17,"minAge":48,"maxAge":346,"enrollmentInfo":347,"targetDuration":4,"studyType":51,"phases":349,"briefSummary":350,"conditions":351,"keywords":358,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":364,"lastUpdatePostDateStruct":365,"startDateStruct":367,"completionDateStruct":369,"leadSponsor":371,"locationsCount":40},"100557571","creating-a-new-health-promotion-module-to-help-the-indigenous-people-of-selangor-prepare-for-disease-x-and-outbreaks-100557571","NCT06539845","Creating a New Health Promotion Module to Help the Indigenous People of Selangor Prepare for Disease X and Outbreaks","Development and Effectiveness of a New Intervention on Household Preparedness for Disease X and Outbreaks Among Orang Asli in Selangor: A Cluster Randomized Trial","Inclusion Criteria:\n\n* Orang Asli ethnicity\n* Malaysian citizen\n* Age between 18 to 99 years old\n* The head of the household, or the person who contributes to, or influences health-related decisions for the household\n* Live in a household with at least three members\n* Able to converse in Malay\n\nExclusion Criteria:\n\n* Having physical or cognitive disabilities (e.g., blindness, deafness, schizophrenia and dementia)\n* Having severe health conditions (e.g., respiratory and cardiovascular disease requiring oxygen support such as severe asthma\u002Fchronic obstructive pulmonary disease\u002Fheart failure and congenital heart diseases)\n* Residing temporarily (less than 2 years)\n* Intending to relocate to a different residence within the next 2 years","99 Years",{"count":348,"type":22},96,[53],"The goal of this cluster randomized trial is to develop and test a new method for preparing indigenous (locally termed as Orang Asli) households in Selangor, a state in Malaysia, for outbreaks and Disease X, a potential unknown infectious threat. It aims to determine if the new method, a health education package comprised of workshops, simulation exercises, and card game play sessions, can enhance the readiness of these families for such outbreaks.\n\nThe main questions it is looking to answer are:\n\n1. Will the intervention package increase the level of preparedness for a Disease X and outbreaks among indigenous households in Selangor?\n2. Will the intervention improve the awareness and attitudes of the indigenous people in Selangor towards outbreak preparedness?\n3. Will it lead to more proactive preparedness actions by these households?\n\nTo evaluate the effectiveness of the intervention package, researchers will compare outcomes between two groups: the intervention group receiving both the intervention package and educational brochures on communicable disease prevention, and the control group receiving only the brochures.\n\nParticipants will:\n\n1. Participate in the activities in the newly developed intervention package, which would include workshops, simulation exercises, and card game play sessions.\n2. Answer surveys four times: before, immediately after, 1 month after and 2 months after the intervention, to measure any changes in their preparedness levels for an outbreak.",[352,27,58,353,354,160,355,356,357],"Attitude to Health","Health-Related Behavior","Health Attitude","Knowledge, Attitudes, Practice","Preparedness","Outbreaks",[359,360,356,361,362,363],"Indigenous People","Aboriginal","Readiness","Community Trial","Outbreak","2025-04-12",{"date":366,"type":32},"2025-04-16",{"date":368,"type":22},"2025-06",{"date":370,"type":22},"2025-09",{"name":372,"class":39},"Universiti Teknologi Mara",{"id":374,"slug":375,"hasResults":11,"nctId":376,"briefTitle":377,"officialTitle":378,"acronym":379,"eligibilityCriteria":380,"healthyVolunteers":288,"sex":17,"minAge":193,"maxAge":19,"enrollmentInfo":381,"targetDuration":4,"studyType":51,"phases":383,"briefSummary":384,"conditions":385,"keywords":387,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":392,"lastUpdatePostDateStruct":393,"startDateStruct":395,"completionDateStruct":397,"leadSponsor":398,"locationsCount":102},"100536394","game-based-pediatric-diabetes-education-100536394","NCT06264258","Game-based Pediatric Diabetes Education","Evaluating Game-based Pediatric Diabetes Education","DVx-T1D","For youth:\n\n* Be between the age of 6 to 12 years.\n* Have been diagnosed with type 1 diabetes for at least 1 year.\n* Be currently taking insulin through multiple daily injections or an insulin pump.\n* Check blood sugar with a meter at least 4 times per day or use a continuous glucose monitor.\n* Be willing to comply with all study visits and procedures.\n\nFor Parent:\n\n* Biological or adopted parent with custody and medical decision making of the patients\n* Living with identified patients\n* Over 18 years old\n* Resident of Allegheny County\n\nExclusion Criteria:\n\n-Children with type 2 diabetes, cystic fibrosis related diabetes, or secondary diabetes.",{"count":382,"type":22},80,[53],"The goal of this study is to evaluate the impact of a mobile app video game called Digital Vaccine for Type 1 Diabetes (DVx-T1D)™, proposed as a low-risk, non-invasive, digital therapeutic candidate for behavior change in children 6 to 12 years of age with Type 1 Diabetes (T1D).\n\nThe investigators hypothesize that adoption of DVx-T1D™ by T1D patients will positively influence healthy dietary and physical activity behaviors by providing nutrition and lifestyle education through a playful, Artificial Intelligence (AI)-based, cartoon-style medium of mobile gaming, and result in improvements in their T1D control. The investigators propose to conduct a longitudinal randomized controlled trial (RCT) over a 3-month period with a study population of 80 T1D participants (40 each in two arms of the trial) of 6-12 years old. The investigators will quantify the impact of the mobile game app plus standard care vs. standard care (with no exposure to the app) on T1D control (assessed by glycosylated hemoglobin or HbA1c measured during clinic visits and continuous glucose monitoring (CGM) parameters measured at home), physical activity levels and food choices of children (measured using food logs and surveys). Game telemetry, food logs, clinical, anthropometric, demographic, and survey data will be collected to obtain adequately powered, theory-driven evidence of the value of game-based approaches delivered via mobile apps.",[386,27],"Diabetes Mellitus, Type 1",[388,389,390,391],"app","game","children","pediatrics","2025-02-10",{"date":394,"type":32},"2025-02-12",{"date":396,"type":32},"2024-05-22",{"date":29,"type":22},{"name":399,"class":39},"Carnegie Mellon University"]