[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bell-palsy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bell-palsy":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,12,0,[8,40,69,92,116,140,164,196,223,250,276,304],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100642502","effect-of-low-energy-extracorporeal-shockwave-on-patients-with-bells-palsy-100642502",false,"NCT07661134","Effect of Low Energy Extracorporeal Shockwave on Patients With Bell's Palsy","Inclusion Criteria:\n\n* Patients with unilateral Bell's palsy (only lower motor neuron lesion).\n* Patient with idiopathic or viral infection, Bell's palsy.\n* The age ranged from 45 to 55 years old.\n* Both males and females are included.\n* Body mass index (18.5-29.9kg\u002Fm2).\n* It includes the patient in the chronic stage.\n* All patients are assessed by NCS and other functional scales.\n* All patients will be referred by neurological consultants.\n* All patients have controlled diabetes mellitus and are medically stable.\n\nExclusion Criteria:\n\n* Patients with a history of facial paralysis post-stroke.\n* Patients with unstable medical conditions.\n* Patients with psychiatric disorders.\n* Patients with other neurological diseases.\n* Patients with other causes for Bell's palsy.\n* Patients with diabetic diseases.","ALL","45 Years","55 Years",{"count":19,"type":20},42,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to investigate the effect of low energy extracorporeal shock wave therapy on patients with Bell's palsy.",[26],"Bell Palsy","NOT_YET_RECRUITING","2026-06-16",{"date":30,"type":31},"2026-06-22","ACTUAL",{"date":33,"type":20},"2026-06-25",{"date":35,"type":20},"2026-09-30",{"name":37,"class":38},"Cairo University","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":15,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":55,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":4},"100632471","electroacupuncture-with-two-pulse-patterns-for-bells-palsy-using-surface-electromyography-evaluation-100632471","NCT07514117","Electroacupuncture With Two Pulse Patterns for Bell's Palsy Using Surface Electromyography Evaluation","Electroacupuncture With Different Pulse Patterns for the Post-acute Phase of Bell's Palsy: a Study Protocol for a Randomized Controlled Trial With Surface Electromyography Evaluation","EABP-SEMG","Inclusion Criteria:\n\n* diagnosed clinically as BP, with imaging evidence (brain CT and\u002For MRI) excluding central nervous system lesions associated with facial palsy\n* the disease duration of 21 days to 6 months, inclusive\n* age 18-70 years\n* voluntary participation and provision of written informed consent\n\nExclusion Criteria:\n\n* facial paralysis caused by other diseases\n* have previous history of facial paralysis\n* present with facial muscle spasm, synkinesis or contracture\n* diagnosed as Ramsey-Hunt Syndrome\n* history of surgery on face\n* with cardiac pacemakers implanted\n* pregnant or lactating patients\n* along with other severe uncontrolled diseases, recognition disorder, aphasia or mental disorders\n* present with bilateral facial paralysis","18 Years","70 Years",{"count":51,"type":20},111,[23],"This clinical trial is designed to evaluate the therapeutic effects of two EA parameter settings for Bell's palsy and to investigate the electromyographic characteristics of the disease. The main questions it aims to answer are:\n\n* Can continuous pulse pattern and intermittent pulse pattern of EA improve the symptoms of Bell's palsy?\n* Do continuous pulse pattern and intermittent pulse pattern of EA impact the electromyographic characteristics of facial muscles in patients with Bell's palsy? The researchers will evaluate the effects of continuous pulse pattern and intermittent pulse pattern in treating Bell's palsy by using surface electromyography as an objective indicator of assessment. The trial lasts for 4 weeks and the treatment period lasts for 4 weeks.\n\nParticipants will:\n\n* receive sham EA, EA with a continuous pulse pattern or EA with an intermittent pulse pattern for 3 times weekly for 4 weeks (12 sessions in total).\n* receive assessment of symptom severity and social functioning on Day 0, end of week 2, end of week 4.",[26],[56,57,58,59],"Bell's palsy","surface electromyography","randomized controlled trial","electroacupuncture","2026-04-27",{"date":62,"type":31},"2026-04-30",{"date":64,"type":20},"2026-05",{"date":66,"type":20},"2027-12",{"name":68,"class":38},"The First Affiliated Hospital of Zhejiang Chinese Medical University",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":15,"minAge":48,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":21,"phases":77,"briefSummary":78,"conditions":79,"keywords":4,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":39},"100632879","different-laser-frequencies-on-neuropathic-outcomes-in-patients-with-bells-palsy-100632879","NCT07519421","Different Laser Frequencies on Neuropathic Outcomes in Patients With Bell's Palsy","Inclusion Criteria:\n\n1. Eighty subjects from both genders diagnosed with Bell's palsy will be recruited through direct referrals from their independent physician's neurology department.\n2. Subjects aged 18 and above from all genders\n3. Unilateral Bell's palsy either on the right or left side.\n4. The Facial disability index will be used for assessment and progression of Bell's palsy before and after treatment protocol.\n5. Patients will on level II, III, IV and V of House-Brackmann scale.\n\nExclusion Criteria:\n\n1. We will exclude patients who had central nervous system pathology, sensory loss over the face, or recurrence of facial palsy.\n2. Upper motor neuron fascial nerve palsy.\n3. Any infant or child (\\\u003C18 years).\n4. Bilateral Facial nerve palsy\n5. Severe hypertension (Blood pressure more than 200\u002F120 mmHg).",{"count":76,"type":20},80,[23],"this study was done to compare different laser frequencies on neuropathic outcomes in patients with Bell's palsy.",[80,26,81],"Neuropathy, Facial","Laser","RECRUITING","2026-04-02",{"date":85,"type":31},"2026-04-09",{"date":87,"type":31},"2025-12-01",{"date":89,"type":20},"2026-06-15",{"name":91,"class":38},"Kafrelsheikh University",{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":11,"sex":15,"minAge":48,"maxAge":99,"enrollmentInfo":100,"targetDuration":4,"studyType":21,"phases":102,"briefSummary":105,"conditions":106,"keywords":4,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":39},"100502347","phase-1-efficacy-of-prednisolone-versus-cerebrolysin-in-the-treatment-of-bells-palsy-100502347","NCT05821075","Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy","Comparative Study Between Prednisolone, Cerebrolysin in the Treatment of Bell's Palsy","Inclusion Criteria:\n\n* unilateral acute facial palsy of no identifiable cause\n\nExclusion Criteria:\n\n* Recurrent facial Bell's palsy\n* Pregnancy\n* Diabetes\n* Epilepsy\n* Severe hypertension,\n* Renal or hepatic disease,\n* Gastric or duodenal ulcer\n* presence of acute otitis media or ipsilateral chronic otitis\n* Recent head injury,\n* psychiatric disease\n* If there is any contraindications for corticosteroids","60 Years",{"count":101,"type":20},90,[103,104],"PHASE1","PHASE2","Bell's palsy, a peripheral facial nerve paresis, is the most common disorder of the facial nerve and one of the most common mononeuropathies.\n\nMany patients with Bell's palsy will develop some complications such as synkinesis, crocodile tears and 'sweating' of the ear while eating Commonly used medications to treat Bell's palsy is Corticosteroids Cerebrolysin stimulates the regeneration of the nervous tissue with protective action we aim to study the efficacy of cerebrolycin in Bell's palsy",[26],"2025-07-28",{"date":109,"type":31},"2025-07-31",{"date":111,"type":31},"2023-08-24",{"date":113,"type":20},"2026-02",{"name":115,"class":38},"October 6 University",{"id":117,"slug":118,"hasResults":11,"nctId":119,"briefTitle":120,"officialTitle":120,"acronym":4,"eligibilityCriteria":121,"healthyVolunteers":11,"sex":15,"minAge":122,"maxAge":16,"enrollmentInfo":123,"targetDuration":4,"studyType":21,"phases":125,"briefSummary":126,"conditions":127,"keywords":128,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":4},"100595106","effectiveness-of-electrical-stimulation-with-mime-therapy-versus-electrical-stimulation-with-proprioceptive-neuromuscular-facilitation-on-improving-facial-asymmetry-and-quality-of-life-in-patients-with-bells-palsy-100595106","NCT07028138","Effectiveness of Electrical Stimulation With Mime Therapy Versus Electrical Stimulation With Proprioceptive Neuromuscular Facilitation on Improving Facial Asymmetry and Quality of Life in Patients With Bell's Palsy","Inclusion Criteria:\n\n* Idiopathic Bell's Palsy Subacute and acute Bell's Palsy\n\nExclusion Criteria:\n\n* UMNL facial palsy patient Non-compliant patient Patient with any psychiatric issues Patients with Dental implants Patients with any Skin condition Patients with Stroke related Bell's Palsy","25 Years",{"count":124,"type":20},38,[23],"To compare the effect of electrical stimulation with mime therapy versus electrical stimulation with proprioceptive neuromuscular facilitation on improving facial asymmetry and quality of life in patients with Bell's palsy.",[26],[129,130],"PNF","ES","2025-06-11",{"date":133,"type":31},"2025-06-19",{"date":135,"type":20},"2025-08-28",{"date":137,"type":20},"2025-12-29",{"name":139,"class":38},"Shalamar Institute of Health Sciences",{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":145,"acronym":4,"eligibilityCriteria":146,"healthyVolunteers":11,"sex":15,"minAge":48,"maxAge":4,"enrollmentInfo":147,"targetDuration":4,"studyType":21,"phases":149,"briefSummary":150,"conditions":151,"keywords":152,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":39},"100575914","intradermal-acupuncture-and-self-rehabilitation-program-in-patients-with-severe-bells-palsy-100575914","NCT06778473","Intradermal Acupuncture and Self-rehabilitation Program in Patients With Severe Bell's Palsy","Effectiveness of Intradermal Acupuncture and Guided Self-rehabilitation Management Program for Severe Bell's Palsy Patients: a Randomized, Placebo-controlled, 2×2 Factorial Trial","Inclusion Criteria:\n\n* Patients diagnosed with Bell's palsy according to \"Clinical Practice Guideline: Bell's Palsy\" published by AAO-HNS in 2013;\n* First onset of Bell's palsy with only one side affected;\n* On the 10th day after the onset of palsy, HBGS score ranging from grade IV to VI;\n* According to the latest Chinese Guidelines for Bell's Palsy, within 72 hours of symptom onset for Bell's Palsy, oraling prednisolone 30mg qd for 5 days, followed by tapering to zero in decrements of 5 mg per day;\n* Adults aged 18 years of age or older (no limitation on gender).\n\nExclusion Criteria:\n\n* Facial paralysis caused by acoustic neuroma, otitis media, mastoiditis, mumps, Hunter's syndrome, cranial base meningitis, intracranial metastasis of cancer or multiple sclerosis;\n* Fear of intradermal acupuncture;\n* allergy to adhesive tape;\n* Severe allergic diseases, significant skin lesions, tumors, and severe or unstable internal diseases involving the cardiovascular, respiratory, endocrine, digestive, or hematological system;\n* Cognitive impairment, mental illness, contagious disease, pregnant and lactating;\n* Previously treated withintradermal acupuncture or participating in other clinical trial within 3 months.",{"count":148,"type":20},552,[23],"This study aims to assess the effect of intradermal acupuncture(IA) and guided self-rehabilitation management program(GRMP) (either single or combined) for patients with severe Bell's Palsy.",[26],[26,153,154],"Intradermal acupuncture","Self-rehabilitation","2025-04-27",{"date":157,"type":31},"2025-04-30",{"date":159,"type":31},"2025-03-24",{"date":161,"type":20},"2029-12-31",{"name":163,"class":38},"Zhangjiagang First People's Hospital",{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":170,"eligibilityCriteria":171,"healthyVolunteers":11,"sex":15,"minAge":172,"maxAge":173,"enrollmentInfo":174,"targetDuration":4,"studyType":21,"phases":176,"briefSummary":178,"conditions":179,"keywords":183,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":195},"100345745","phase-4-evaluation-of-cortisone-treatment-in-children-with-acute-facial-nerve-palsy-100345745","NCT03781700","Evaluation of Cortisone Treatment in Children With Acute Facial Nerve Palsy","The Facial Nerve Palsy And Cortisone Evaluation (FACE) Study in Children: A Randomized Double-blind, Placebo-controlled, Multicenter Trial","FACE","Inclusion Criteria:\n\n1. 1-17 years of age\n2. Acute peripheral unilateral facial nerve palsy\n3. Less than 72 hours since debut of symptoms\n4. Signed informed consent\n\nExclusion Criteria:\n\n1. Head trauma \\\u003C1 month\n2. Central or bilateral facial nerve palsy\n3. Malformations in head and neck\n4. Conditions not compatible with cortisone treatment (arterial hypertension, diabetes mellitus, psychiatric disorder, active or latent tuberculosis, intolerance of lactose)\n5. Current or past oncological diagnosis\n6. Other serious medical conditions (meningitis, encephalitis, stroke)\n7. Acute otitis media\n8. Signs of herpes simplex or varicella zoster infection (vesicles in the ear region)\n9. Pregnancy or breastfeeding\n10. Use of any systemic or inhaled steroids within 2 weeks prior onset of symptoms\n11. Immunization with live vaccine 1 month prior onset of symptoms\n12. Requirement of live vaccine within 2 months from start of experimental treatment (prednisolone or placebo)\n13. Evaluation of primary endpoint at 12 months not feasible for any reason\n14. Previously included into the FACE study","1 Year","17 Years",{"count":175,"type":20},500,[177],"PHASE4","Acute facial nerve palsy occur in 10-20\u002F100 000 children\u002Fyear in Sweden. About 20 % of these children will have persistent symptoms with excessive tear secretion, drooling and social problems due to asymmetry in the face. Studies on cortisone treatment to adult patients with acute facial nerve palsy have shown beneficial effects, but no studies with strong quality have been performed in children.\n\nInvestigators will perform a double-blind randomized placebo-controlled multicenter trial on children with acute facial nerve palsy. Participants will be recruited consecutively at 9-12 study centers in Sweden during 2019-2020. Oral cortisone (prednisolone) 1 mg\u002Fkg x 1 in 10 days (or placebo) will be started on admission. Clinical data, including recovery will be followed-up until 12 months.\n\nThe primary outcome is defined as total recovery of the facial nerve palsy, measured with the House-Brackmann scale (grade 1) at 12-months follow-up.\n\nThe overall purpose is to assess the utility of cortisone treatment given to children with acute facial nerve palsy in this study. If the total recovery rate is significantly improved in the prednisolone group as compared to the placebo group, prednisolone treatment will be introduced in clinical practice for children with acute facial nerve palsy in order to reduce the risk of persistent symptoms.",[180,181,182,26],"Facial Palsy","Facial Nerve Diseases","Borrelia Infection of Central Nervous System",[184,185],"Children","Paediatric","2025-02-20",{"date":188,"type":31},"2025-02-21",{"date":190,"type":31},"2019-05-03",{"date":192,"type":20},"2026-12-31",{"name":194,"class":38},"Dalarna County Council, Sweden",15,{"id":197,"slug":198,"hasResults":11,"nctId":199,"briefTitle":200,"officialTitle":200,"acronym":4,"eligibilityCriteria":201,"healthyVolunteers":202,"sex":15,"minAge":48,"maxAge":203,"enrollmentInfo":204,"targetDuration":205,"studyType":206,"phases":4,"briefSummary":207,"conditions":208,"keywords":210,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":214,"startDateStruct":216,"completionDateStruct":218,"leadSponsor":220,"locationsCount":222},"100573153","the-relationship-between-idiopathic-acute-peripheral-facial-paralysis-and-homocysteine-level-in-adult-patients-100573153","NCT06742580","The Relationship Between Idiopathic Acute Peripheral Facial Paralysis and Homocysteine Level in Adult Patients","Inclusion Criteria:\n\n\\- Patients admitted with acute facial paralysis\n\nExclusion Criteria:\n\n* Facial and ear trauma or tumor\n* İatrogenic\n* Cholesteatoma\n* Facial paralysis due to central nervous system diseases",true,"80 Years",{"count":76,"type":20},"2 Months","OBSERVATIONAL","In the etıology of Idıopathıc Acute Perıpheral Facıal Palsy, known as bell palsy, many causes have been descrıbed, such as specıfıc ımmune, ıchemıc, ınfectıous and heredıal factors. ın our study, we have observed the blood homocysteıne level that causes thrombotıc dısorders ın paralysıs patıents.",[209,26],"Facial Paralysis, Peripheral",[211,212,26],"Acute Peripheral Facial Paralysis","Homocysteine","2024-12-18",{"date":215,"type":31},"2024-12-19",{"date":217,"type":31},"2023-12-01",{"date":219,"type":20},"2025-08-04",{"name":221,"class":38},"Murat Akın",3,{"id":224,"slug":225,"hasResults":11,"nctId":226,"briefTitle":227,"officialTitle":228,"acronym":4,"eligibilityCriteria":229,"healthyVolunteers":11,"sex":15,"minAge":48,"maxAge":230,"enrollmentInfo":231,"targetDuration":4,"studyType":21,"phases":233,"briefSummary":234,"conditions":235,"keywords":236,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":241,"lastUpdatePostDateStruct":242,"startDateStruct":244,"completionDateStruct":246,"leadSponsor":248,"locationsCount":39},"100572388","laser-acupuncture-for-idiopathic-bells-palsy-100572388","NCT06732622","Laser Acupuncture for Idiopathic Bell's Palsy","Laser Acupuncture for Idiopathic Bell's Palsy: a Randomized Controlled Trial","Inclusion Criteria:\n\n* 1\\. Patients diagnosed with idiopathic Bell's Palsy 2.Patients were eligible if they were graded at House-Brackmann grade (HB) 3 or higher.\n\nExclusion Criteria:\n\n* 1\\. Serious mental illness or social problems, and neurological disorders, and systemic diseases, such as malignant tumors, and other serious consumptive diseases. 2. Planning for pregnancy, those in pregnancy, or those who were lactating. 3.Bell's Palsy patients who have a disease course of more than 8 weeks.","65 Years",{"count":232,"type":20},360,[23],"Bell's palsy is characterized by acute, unilateral onset that compromises function and esthetics, exerting a considerable impact on the social, professional, and psychological aspects of the lives of affected individuals. The objective of this study was to determine whether laser acupuncture therapy could relieve symptoms in patients with Bell's palsy.",[26],[237,238,239,240],"Bell's Palsy","Laser acupuncture","Photobiomodulation","RCT","2024-12-10",{"date":243,"type":31},"2024-12-13",{"date":245,"type":31},"2024-12-01",{"date":247,"type":20},"2026-06-01",{"name":249,"class":38},"Beijing Tongren Hospital",{"id":251,"slug":252,"hasResults":11,"nctId":253,"briefTitle":254,"officialTitle":255,"acronym":256,"eligibilityCriteria":257,"healthyVolunteers":11,"sex":15,"minAge":48,"maxAge":4,"enrollmentInfo":258,"targetDuration":4,"studyType":206,"phases":4,"briefSummary":260,"conditions":261,"keywords":262,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":267,"lastUpdatePostDateStruct":268,"startDateStruct":270,"completionDateStruct":272,"leadSponsor":274,"locationsCount":39},"100484044","screening-for-prognostic-biomarkers-of-severe-bells-palsy-in-adults-100484044","NCT05582915","Screening for Prognostic Biomarkers of Severe Bell's Palsy in Adults","Screening for Prognostic Biomarkers of Severe Bell's Palsy in Adults Using Proteomic Analysis by Quantitative Mass Spectroscopy","BIOFIPS","Inclusion Criteria:\n\n* Severe Bell's palsy (House-Brackmann more or equal to IV)\n* Disease developed between 5 and 15 days before V0 (after initial corticotherapy)\n* 18 years and older\n\nExclusion Criteria:\n\n* Facial palsy (central or peripheral) of a following cause suspected at V0:\n\nDiabetes, syphilis, HIV-1 or HIV-2 infection, Lyme disease, herpes zoster infection of the geniculate ganglion; Inflammatory or immune pathology, acute or chronic; Intracranial, parotid or facial nerve tumor; Craniofacial injury; Other peripheral neuropathy\n\n* Anti-inflammatoty, immunomodulating, immunosuppressive treatment\n* Contraindications for an MRI scan\n* Contraindications for a standard medical treatment: prednisone 1 mg per kg a day during 5 days and valaciclovir 3 g a day during 7 days\n* Contraindications for or an impossibility of facial physiotheraphy (2 times per week along with everyday self-theraphy)\n* Pregnancy or breastfeeding\n* Participation to another interventional study\n* Patient unaffiliated to French Social Security regime\n* Patients' refusal to consent to participation in the study\n* Person prived of liberty by judicial or administrative decision\n* Person protected by law (under guardianship or curatorship)\n* Person not able to understand the nature, the aim and the methodology of the study",{"count":259,"type":20},130,"Bell's palsy (idiopathic peripheral facial palsy) is the most common cause of facial palsy, which is related to the inflammation of the facial nerve, possibly induced by herpesvirus reactivation. Its first-line treatment comprises corticosteroids, antiviral therapy and physiotherapy. In most severe cases (grade IV to VI on House-Brackmann scale), facial motricity may remain altered or develop synkinesis or post-paralytic spasm, thus tremendously affecting quality of life. To avoid potential complications, surgical facial nerve decompression could be proposed. To date, however, there are no means to predict if Bell's palsy will evolve with any complications or if the patient will recover entirely. Thus, the invasive facial nerve decompression is equally proposed to subjects who will develop the consequences as well as to subjects able to restore without surgical treatment. This study proposes to search for prognostic blood biomarkers related to the Bell's palsy recovery pattern. Adult patients with severe Bell's palsy will be proposed to have a blood sampling for proteomic analysis in the early stage of the disease. Then 125 biomarkers on a Peptiquant™ kit will be analysed by mass spectrometry, and prognostic biomarkers will be selected regarding to the clinical recovery of Bell's palsy",[26],[56,263,264,265,266],"Proteomics","Biomarkers","Mass spectroscopy","Prognosis","2024-08-19",{"date":269,"type":31},"2024-08-20",{"date":271,"type":31},"2023-01-03",{"date":273,"type":20},"2026-07",{"name":275,"class":38},"University Hospital, Montpellier",{"id":277,"slug":278,"hasResults":11,"nctId":279,"briefTitle":280,"officialTitle":281,"acronym":4,"eligibilityCriteria":282,"healthyVolunteers":11,"sex":15,"minAge":283,"maxAge":284,"enrollmentInfo":285,"targetDuration":4,"studyType":21,"phases":287,"briefSummary":288,"conditions":289,"keywords":290,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":295,"lastUpdatePostDateStruct":296,"startDateStruct":298,"completionDateStruct":300,"leadSponsor":302,"locationsCount":39},"100551418","mime-therapy-with-and-without-neural-mobilization-in-bells-palsy-100551418","NCT06459830","Mime Therapy With and Without Neural Mobilization in Bell's Palsy.","Effects of Mime Therapy With and Without Neural Mobilization on Facial Symmetry, Synkinesis and Functional Abilities in Patients With Bell's Palsy.","Inclusion Criteria:\n\nIdiopathic bell's palsy. Age between 20 to 40 years. Both genders Sub-acute Bell's palsy lasting 3-6 months. Unilateral loss of facial weakness Intact taste sensation. House Brackman grade 4 and 5 (moderate to severe Bell's palsy)\n\nExclusion Criteria:\n\nFacial palsy recurrence. Patients with Diabetes, Hypertension, and any Auto-immune disorder. Chronic bell's palsy patients Patients with upper motor neuron lesions. Other cranial nerves problem. Pregnancy. Dental metal prosthesis. Facial surgery Skin allergy on face. Patients with Ear infection. Patients with Ear implants. Any neuro-degenerative disorder. Patients with Herpes zoster, Otitis media and Ramsay Hunt syndrome","20 Years","40 Years",{"count":286,"type":20},32,[23],"To determine the Effects of Mime Therapy with and without Neural Mobilization on Facial symmetry, Synkinesis and Functional abilities in Patients with Bell's Palsy.\n\nIt has been proven that Mime therapy is effective on activating muscles through articulation exercises, facial expression exercises, breathing exercises and facial massages which can alleviate synkinesis, enhance facial symmetry and promote facial functional abilities. On the other hand, facial neural mobilization has recently reported as a safe and effective adjunctive therapy for patients with Bell's palsy due to the facilitation of nerve gliding in the canal impacts by reducing nerve adherence dispersion of noxious inflammatory agents and increasing neural blood supply. So, by incorporating the Neural mobilization with Mime therapy, therapist may enhance overall facial symmetry, reduce the strain on the facial muscles and alleviate synkinesis. So, it may prove to be an upgraded treatment option for clinicians.",[26],[56,291,292,293,294],"Facial Asymmetry","Facial Paralysis","Mime therapy","Mobilization","2024-06-11",{"date":297,"type":31},"2024-06-14",{"date":299,"type":31},"2024-03-25",{"date":301,"type":20},"2024-12-15",{"name":303,"class":38},"Riphah International University",{"id":305,"slug":306,"hasResults":11,"nctId":307,"briefTitle":308,"officialTitle":308,"acronym":4,"eligibilityCriteria":309,"healthyVolunteers":11,"sex":15,"minAge":48,"maxAge":4,"enrollmentInfo":310,"targetDuration":4,"studyType":21,"phases":311,"briefSummary":312,"conditions":313,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":314,"lastUpdatePostDateStruct":315,"startDateStruct":317,"completionDateStruct":319,"leadSponsor":321,"locationsCount":4},"100532485","role-of-oral-steroid-alone-versus-oral-steroid-plus-intratympanic-steroid-injection-in-bells-palsy-100532485","NCT06213415","Role of Oral Steroid Alone Versus Oral Steroid Plus Intratympanic Steroid Injection in Bell's Palsy","Inclusion Criteria:\n\n* Mean Aged 18 years or more.\n\n  * Acute unilateral facial palsy without skin lesions which developed within a 72-hour period and is present for 21 days or less.\n  * Moderate to severe facial palsy \\[House-Brackmann grade IV or greater\\]\n\nExclusion Criteria:\n\n* Another cause of facial nerve paralysis that is not idiopathic.\n\n  * Otologic disease including otitis media, temporal bone fracture, a previous history of facial nerve palsy in either side, history of otologic surgery, and suspected Ramsay Hunt syndrome.\n  * Systemic disease including history of tuberculosis, history of head and neck cancer, other neurological disorders, recent use of ototoxic medications, liver or renal dysfunction, and other illnesses that would contraindicate the use of high-dose steroid therapy.\n  * Pregnancy",{"count":19,"type":20},[23],"intratympanic steroid injection bell's palsy",[26],"2024-01-09",{"date":316,"type":31},"2024-01-19",{"date":318,"type":20},"2024-02",{"date":320,"type":20},"2026-11",{"name":322,"class":38},"Assiut University"]