[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"benign-paroxysmal-positional-vertigo-bppv\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:benign-paroxysmal-positional-vertigo-bppv":23},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,40,68,90],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":24,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100630768","association-between-benign-paroxysmal-positional-vertigo-and-vitamin-d-deficiency--100630768",false,"NCT07491965","Association Between Benign Paroxysmal Positional Vertigo and Vitamin D Deficiency .","Association Between Benign Paroxysmal Positional Vertigo and Vitamin D Deficiency ; Sohag University Hospital Experience.","Inclusion Criteria:\n\n* • Cases: Adults with a confirmed diagnosis of idiopathic BPPV based on positive Dix-Hallpike maneuver (nystagmus and vertigo lasting \\\u003C1 minute).\n\n  * Controls: Adults attending ENT clinic without history of vertigo or BPPV, confirmed by negative Dix-Hallpike test.\n\nExclusion Criteria:\n\n* Known causes of secondary vertigo (e.g., Meniere's disease, vestibular neuritis, central vertigo).\n\n  * Conditions affecting vitamin D metabolism (e.g., chronic kidney disease, malabsorption syndromes, hyperparathyroidism).\n  * Use of medications interfering with vitamin D levels (e.g., anticonvulsants, glucocorticoids) in the past 3 months.\n  * Pregnancy or lactation.\n  * Inability to provide consent.","ALL",{"count":18,"type":19},160,"ESTIMATED","OBSERVATIONAL","Association between Benign Paroxysmal Positional Vertigo and Vitamin D deficiency",[23],"Benign Paroxysmal Positional Vertigo (BPPV)",[25,26],"Vitamin D deficiency","Benign Paroxysmal Positional Vertigo","RECRUITING","2026-06-16",{"date":30,"type":31},"2026-06-18","ACTUAL",{"date":33,"type":31},"2026-04-01",{"date":35,"type":19},"2026-10-01",{"name":37,"class":38},"Sohag University","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":16,"minAge":47,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":55,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":39},"100601477","testing-the-epley-maneuver-for-treating-dizziness-in-the-emergency-department-100601477","NCT07111000","Testing the Epley Maneuver for Treating Dizziness in the Emergency Department","Evaluating the Efficacy of Epley Maneuver in the Treatment of Benign Paroxysmal Positional Vertigo in the Emergency Department: A Randomized Controlled Trial.","Inclusion Criteria\n\n* Age: above 18 years old\n* Patients presenting to the ED with symptoms of BPPV (single or recurrent episodes of vertigo lasting up to 2 minutes) and a positive DHT (episode of vertigo associated with torsional upbeating nystagmus) indicating a posterior semicircular canal BPPV.\n* Patients who are able to understand and provide a signed informed consent to participate in the study Exclusion Criteria\n* Severe cervical diseases (e.g., soft tissue disorders, cervical spondylosis, prolapsed intervertebral disks and severe rheumatoid arthritis with cervical instability …)\n* Unstable cardiovascular diseases (e.g., hemodynamically unstable, decompensated heart failure, acute myocardial infarction, decompensated valvular diseases, severe arrhythmias …)\n* Suspected vertebrobasilar diseases (e.g., cerebellar signs, vision changes, numbness or tingling in the extremities, slurred speech, changes in mental status, confusion …)\n* History of high-grade carotid stenosis\n* Recent (\\\u003C24 hours) intake of aminoglycosides, chemotherapeutic agents, cyclophosphamide, loop diuretics, or quinines\n* Patients with peripheral causes of vertigo other than BPPV (such as Meniere's disease or vestibular neuritis)\n* Patients with central causes of vertigo (vestibular migraine, Arnold Chiari malformation, history of CNS tumor(s), multiple sclerosis)\n* Patients with focal deficits on neurological exam\n* Patients with an episode of vertigo lasting more than 2 minutes\n* Patients with a negative DHT\n* Patients with pure horizontal or vertical nystagmus\n* Patients with lateral and anterior semicircular canals BPPV\n* Participants refusing to undergo Epley maneuver\n* Pregnancy beyond the 24th week of gestation","18 Years",{"count":49,"type":19},118,"INTERVENTIONAL",[52],"NA","The goal of this randomized controlled trial is to evaluate the efficacy of the Epley maneuver versus a sham maneuver in treating patients presenting to the emergency department (ED) with BPPV. The main questions that the study aims to answer are:\n\n* What is the mean difference in Dizziness Handicap Inventory (DHI) scores between patients receiving the Epley maneuver and those receiving the sham maneuver 3 days after enrollment?\n* What is the immediate response (using a 0-10-point Likert scale) of patients in each arm of the study?\n* What is the proportion of patients who, despite agreeing to participate, were unable to complete the full Epley maneuver due to symptom severity?\n\nResearchers will compare the Epley maneuver arm to the sham maneuver arm to see if the Epley maneuver is more effective in reducing BPPV symptoms.\n\nParticipants will:\n\n* Undergo either the Epley maneuver or a sham maneuver.\n* Complete the Dizziness Handicap Inventory (DHI) questionnaire at baseline and 3 days post-discharge.\n* Patients with insufficient improvement in the sham maneuver group will receive a rescue Epley maneuver.\n* Have their vertigo severity assessed using a 0-10 point Likert scale at baseline, immediately and post-maneuver.",[23],[56,57,58],"Epley","vertigo","bening paroxysmal positional vertigo","2026-05-06",{"date":61,"type":31},"2026-05-11",{"date":63,"type":31},"2024-08-01",{"date":65,"type":19},"2026-08-22",{"name":67,"class":38},"American University of Beirut Medical Center",{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":16,"minAge":75,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":78,"conditions":79,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":39},"100565555","prevalence-av-bppv-among-elderly-in-primary-care-100565555","NCT06643702","Prevalence av BPPV Among Elderly in Primary Care","Screening for Benign Paroxysmal Positional Vertigo in Primary Care Among Elderly Presenting With Dizziness, Imbalance, and Increased Tendency to Fall","Inclusion Criteria:\n\nPatients aged 65 years or older and present to the primary care clinic with one or several of the following:\n\n1. Acute, episodic, or chronic sensation of dizziness\u002Fvertigo.\n2. Subjective or objective imbalance during stance or movements.\n3. Presented with increased tendency of falls by exhibiting unintentional loss of balance resulting in a fall one or more times in the past 12 months.\n\nExclusion Criteria:\n\n1. Patients not meeting the above epidemiological and medical criteria described under \"Inclusion Criteria\".\n2. Patients presenting with pathologies in which head and neck movements\u002Fmanipulations are contraindicated, including (but not limited to): cervical instability, acute head and neck trauma, known cervical disk prolapse, Arnold-Chiari malformation, vascular pathologies such as carotid sinus syncope, vascular dissection and vertebrobasilarinsufficiency, including patients with paralysis as well as those with reduced mobility, in whom diagnostic maneuvers cannot be correctly performed.","65 Years",{"count":77,"type":19},115,"This study aims to investigate whether positional tests should be routinely performed on all elderly patients (65 years and older) presenting to primary care with symptoms of acute, episodic, or chronic dizziness or vertigo, unsteadiness, imbalance, and\u002For an increased tendency to fall in the past 12 months. Study aims to investigate whether diagnostic maneuvers should be performed regardless of the presence of conventional positional vertigo presentation associated with classical cases of benign paroxysmal positional vertigo (BPPV). Specifically, the study aims to identify \"hidden\" cases of BPPV and assess the potential benefits of clinical screening and initial treatment of BPPV in primary care setting thus improving the BPPV-related quality of life and reducing the risk of falls in the elderly population.",[23],"2024-10-24",{"date":82,"type":31},"2024-10-28",{"date":84,"type":31},"2024-10-16",{"date":86,"type":19},"2026-12",{"name":88,"class":89},"Region Stockholm","OTHER_GOV",{"id":91,"slug":92,"hasResults":11,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":4,"eligibilityCriteria":96,"healthyVolunteers":11,"sex":16,"minAge":97,"maxAge":75,"enrollmentInfo":98,"targetDuration":4,"studyType":50,"phases":100,"briefSummary":101,"conditions":102,"keywords":104,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":39},"100564139","effects-of-epleys-maneuver-versus-semont-plus-maneuver-combined-with-brandt-daroff-exercises-on-dizziness-and-quality-of-life-in-benign-paroxysmal-positional-vertigo-100564139","NCT06625281","Effects of Epleys Maneuver Versus Semont-Plus Maneuver Combined with Brandt-Daroff Exercises on Dizziness and Quality of Life in Benign Paroxysmal Positional Vertigo","Effects of Epleys Maneuver Versus Semont-Plus Maneuver Combined with Brandt-Daroff Exercises on Dizziness and Quality of Life in Benign Paroxysmal Positional Vertigo;","Inclusion Criteria:\n\n* Both genders\n* Positive Dix Hallpike test.\n* Patients diagnosed with Posterior canal Benign Paroxysmal Positional Vertigo.\n* Patients with recurrent episodes of dizziness.\n* Age group 20-65.\n* Positive Dix Hallpike Test\n\nExclusion Criteria:\n\n* Dix Hallpike test negative.\n* DHI Scale: 54+ Severe\n* Trauma\n* Ankylosing spondylitis\n* Cervical pathology-related dizziness\n* Spinal cord injury\n* Carotid stenosis\n* Other Vestibular pathologies (Meniere's disease, Vestibular hypofunction, Labyrinthitis","20 Years",{"count":99,"type":19},40,[52],"Vestibular hypofunction can result in symptoms consisting of dizziness, imbalance, and\u002For oscillopsia, gaze and gait instability, and impaired navigation and spatial orientation; thus, may negatively impact an individual\\'s quality of life, and ability to perform activities of daily living.\n\nBenign paroxysmal positional vertigo (BPPV) is the most common peripheral vestibular disorder which occurs with changing of the positions lying down, rolling over, climbing stairs, or looking up and down. The typical symptoms include dizziness, loss of balance, nystagmus, and nausea, limiting the daily activities of life and functional capacity.\n\nMuch research has been done to rule out the prime treatment for posterior canal-BPPV using vestibular rehabilitation therapy (VRT), Canalith repositioning maneuvers (CRM), and habituation exercises, but scarce literature renders the combination of maneuvers and exercises.\n\nThe current study will be used to determine and compare the effects of Epley\\'s maneuver Versus the Semont-Plus maneuver combined with Brandt-Daroff exercises on Dizziness and Quality of life in participants with pc-Benign paroxysmal positional vertigo. The participants having clinically diagnosed Posterior canal Benign paroxysmal positional vertigo (BPPV) will be selected in this study.\n\nThe outcome measure will be the Dizziness Handicap Inventory (DHI) to assess the Dizziness in participants and Vestibular activities and the participation measure (VAP) will assess the Quality of life. For such a randomized control trial a sample of 40 participants will be taken with 20 participants in each group will be included in the study. One group will undergo Epley's Maneuver and Brandt-daroff exercises and the second group will receive Semont-plus maneuver and Brandt-daroff exercises. Scores will be taken again after intervention. The study will be conducted over 1 year at Fauji Foundation Hospital and Foundation University Islamabad. Participants of interest would be approached and explained about the research. Informed written consent will be taken first. Recruited participants will be allocated to either of the groups through a convenient sampling method.\n\nAll outcome measurements would be performed first at baseline and then after the 6 weeks intervention period..",[103,23],"Dizziness",[105,106,26],"PhysicalTherapy","Vestibular Rehabilitation Therapy","2024-10-01",{"date":109,"type":31},"2024-10-03",{"date":111,"type":31},"2024-07-20",{"date":113,"type":19},"2024-12-20",{"name":115,"class":38},"Foundation University Islamabad"]