[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"benign-vocal-fold-lesions\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:benign-vocal-fold-lesions":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100616068","effect-of-prp-injection-on-voice-recovery-after-benign-vocal-fold-surgery-100616068",false,"NCT07300800","Effect of PRP Injection on Voice Recovery After Benign Vocal Fold Surgery","Evaluating The Efficacy of Platelet Rich Plasma on Voice Outcomes Following Surgical Removal of Benign Vocal Fold Lesions","* Inclusion Criteria:\n\n  \\* Adults aged 18 to 50 years\n\n  \\* Diagnosis of a benign vocal fold lesion, including: Vocal fold polyps Vocal fold cysts Vocal fold nodules\n\n  \\* Failure to respond to conservative management, including one or more of the following: Voice rest, voice therapy\n* Exclusion Criteria:\n\n  * Age younger than 18 years or above 50\n  * Medically unfit for surgery","ALL","18 Years","50 Years",{"count":20,"type":21},64,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to evaluate whether platelet-rich plasma (PRP) injections can improve voice outcomes after microlaryngosurgery in patients with benign vocal fold lesions. The main questions it aims to answer are:\n\nDoes postoperative PRP injection improve vocal quality compared to conventional surgery alone?\n\nDoes PRP injection reduce vocal fatigue and improve patients' voice-related quality of life?\n\nResearchers will compare 32 patients receiving PRP injections after surgical removal of lesions (intraoperative injection) to 32 patients undergoing conventional surgery without PRP to see if PRP enhances recovery and voice function.\n\nParticipants will:\n\nUndergo microlaryngosurgery to remove benign vocal fold lesions.\n\nReceive a PRP injection to the operated vocal fold and standard postoperative care.\n\nOr Standard postoperative care only.\n\nComplete voice assessments before surgery and at 1 and 3 months after surgery, including:\n\nAuditory perceptual evaluation (GRBAS scale) Videostroboscopy Acoustic and aerodynamic voice analysis Vocal Fatigue Index (VFI)\n\nAll participants will provide written consent and undergo standard preoperative assessments including medical history, ENT examination, laboratory tests, ECG, and anesthesia evaluation.",[27],"Benign Vocal Fold Lesions",[29,30,31],"vocal fold polyp","vocal fold nodules","vocal fold cyst","RECRUITING","2026-05-29",{"date":35,"type":36},"2026-06-01","ACTUAL",{"date":38,"type":36},"2025-03-04",{"date":40,"type":21},"2026-07-30",{"name":42,"class":43},"Beni-Suef University","OTHER"]